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Clinical Potential of Kinase Inhibitors in Combination with Immune Checkpoint Inhibitors for the Treatment of Solid Tumors.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2608, doi. 10.3390/ijms22052608
By:
- Ahn, Ryuhjin;
- Ursini-Siegel, Josie;
- West, A. Phillip
Publication type:
Article
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23396-2
By:
- Totten, Stephanie P.;
- Im, Young Kyuen;
- Cepeda Cañedo, Eduardo;
- Najyb, Ouafa;
- Nguyen, Alice;
- Hébert, Steven;
- Ahn, Ryuhjin;
- Lewis, Kyle;
- Lebeau, Benjamin;
- La Selva, Rachel;
- Sabourin, Valérie;
- Martínez, Constanza;
- Savage, Paul;
- Kuasne, Hellen;
- Avizonis, Daina;
- Santos Martínez, Nancy;
- Chabot, Catherine;
- Aguilar-Mahecha, Adriana;
- Goulet, Marie-Line;
- Dankner, Matthew
Publication type:
Article
p66ShcA functions as a contextual promoter of breast cancer metastasis.
Published in:
2020
By:
- Lewis, Kyle;
- Kiepas, Alex;
- Hudson, Jesse;
- Senecal, Julien;
- Ha, Jacqueline R.;
- Voorand, Elena;
- Annis, Matthew G.;
- Sabourin, Valerie;
- Ahn, Ryuhjin;
- La Selva, Rachel;
- Tabariès, Sébastien;
- Hsu, Brian E.;
- Siegel, Matthew J.;
- Dankner, Matthew;
- Canedo, Eduardo Cepeda;
- Lajoie, Mathieu;
- Watson, Ian R.;
- Brown, Claire M.;
- Siegel, Peter M.;
- Ursini-Siegel, Josie
Publication type:
journal article
Antigen presentation deficiency, mesenchymal differentiation, and resistance to immunotherapy in the murine syngeneic CT2A tumor model.
Published in:
Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2023.1297932
By:
- Iorgulescu, J. Bryan;
- Ruthen, Neil;
- Ryuhjin Ahn;
- Panagioti, Eleni;
- Gokhale, Prafulla C.;
- Neagu, Martha;
- Speranza, Maria C.;
- Eschle, Benjamin K.;
- Soroko, Kara M.;
- Piranlioglu, Raziye;
- Datta, Meenal;
- Krishnan, Shanmugarajan;
- Yates, Kathleen B.;
- Baker, Gregory J.;
- Jain, Rakesh K.;
- Suvà, Mario L.;
- Neuberg, Donna;
- White, Forest M.;
- Chiocca, E. Antonio;
- Freeman, Gordon J.
Publication type:
Article
The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14638, doi. 10.1038/ncomms14638
By:
- Ahn, Ryuhjin;
- Sabourin, Valérie;
- Bolt, Alicia M.;
- Hébert, Steven;
- Totten, Stephanie;
- De Jay, Nicolas;
- Festa, Maria Carolina;
- Young, Yoon Kow;
- Im, Young Kyuen;
- Pawson, Tony;
- Koromilas, Antonis E.;
- Muller, William J.;
- Mann, Koren K.;
- Kleinman, Claudia L.;
- Ursini-Siegel, Josie
Publication type:
Article

Found: 5

Clinical Potential of Kinase Inhibitors in Combination with Immune Checkpoint Inhibitors for the Treatment of Solid Tumors.

STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.

p66ShcA functions as a contextual promoter of breast cancer metastasis.

Antigen presentation deficiency, mesenchymal differentiation, and resistance to immunotherapy in the murine syngeneic CT2A tumor model.

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.