Works by Aghajanian, Carol


Results: 40
    1

    A novel representation of inter-site tumour heterogeneity from pre-treatment computed tomography textures classifies ovarian cancers by clinical outcome.

    Published in:
    2017
    By:
    • Vargas, Hebert;
    • Veeraraghavan, Harini;
    • Micco, Maura;
    • Nougaret, Stephanie;
    • Lakhman, Yulia;
    • Meier, Andreas;
    • Sosa, Ramon;
    • Soslow, Robert;
    • Levine, Douglas;
    • Weigelt, Britta;
    • Aghajanian, Carol;
    • Hricak, Hedvig;
    • Deasy, Joseph;
    • Snyder, Alexandra;
    • Sala, Evis;
    • Vargas, Hebert Alberto;
    • Meier, Andreas A;
    • Soslow, Robert A;
    • Levine, Douglas A
    Publication type:
    journal article
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    ERBB2 mutations define a subgroup of endometrial carcinomas associated with high tumor mutational burden and the microsatellite instability‐high (MSI‐H) molecular subtype.

    Published in:
    Molecular Oncology, 2024, v. 18, n. 10, p. 2356, doi. 10.1002/1878-0261.13698
    By:
    • Brodeur, Melica Nourmoussavi;
    • Selenica, Pier;
    • Ma, Weining;
    • Moufarrij, Sara;
    • Dagher, Christian;
    • Basili, Thais;
    • Abu‐Rustum, Nadeem R.;
    • Aghajanian, Carol;
    • Zhou, Qin;
    • Iasonos, Alexia;
    • Ellenson, Lora H.;
    • Weigelt, Britta;
    • Chui, M. Herman
    Publication type:
    Article
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    ERBB2 mutations define a subgroup of endometrial carcinomas associated with high tumor mutational burden and the microsatellite instability‐high (MSI‐H) molecular subtype.

    Published in:
    Molecular Oncology, 2024, v. 18, n. 10, p. 2356, doi. 10.1002/1878-0261.13698
    By:
    • Brodeur, Melica Nourmoussavi;
    • Selenica, Pier;
    • Ma, Weining;
    • Moufarrij, Sara;
    • Dagher, Christian;
    • Basili, Thais;
    • Abu‐Rustum, Nadeem R.;
    • Aghajanian, Carol;
    • Zhou, Qin;
    • Iasonos, Alexia;
    • Ellenson, Lora H.;
    • Weigelt, Britta;
    • Chui, M. Herman
    Publication type:
    Article
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    Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2).

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22582-6
    By:
    • Swisher, Elizabeth M.;
    • Kwan, Tanya T.;
    • Oza, Amit M.;
    • Tinker, Anna V.;
    • Ray-Coquard, Isabelle;
    • Oaknin, Ana;
    • Coleman, Robert L.;
    • Aghajanian, Carol;
    • Konecny, Gottfried E.;
    • O'Malley, David M.;
    • Leary, Alexandra;
    • Provencher, Diane;
    • Welch, Stephen;
    • Chen, Lee-may;
    • Wahner Hendrickson, Andrea E.;
    • Ma, Ling;
    • Ghatage, Prafull;
    • Kristeleit, Rebecca S.;
    • Dorigo, Oliver;
    • Musafer, Ashan
    Publication type:
    Article
    7

    Olaparib as treatment for platinum‐sensitive relapsed ovarian cancer by BRCA mutation and homologous recombination deficiency: Phase 2 LIGHT study final overall survival analysis.

    Published in:
    Cancer (0008543X), 2025, v. 131, n. 2, p. 1, doi. 10.1002/cncr.35707
    By:
    • Liu, Ying L.;
    • Mathews, Cara A.;
    • Simpkins, Fiona;
    • Cadoo, Karen A.;
    • Provencher, Diane;
    • McCormick, Colleen C.;
    • ElNaggar, Adam C.;
    • Altman, Alon D.;
    • Gilbert, Lucy;
    • Black, Destin;
    • Kabil, Nashwa;
    • Taylor, Rosie N.;
    • Barnicle, Alan;
    • Munley, Jiefen Y.;
    • Aghajanian, Carol
    Publication type:
    Article
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    Immunization of ovarian cancer patients with a synthetic Lewis.

    Published in:
    International Journal of Cancer, 2000, v. 87, n. 1, p. 79, doi. 10.1002/1097-0215(20000701)87:1<79::AID-IJC12>3.0.CO;2-L
    By:
    • Sabbatini, Paul J.;
    • Kudryashov, Valery;
    • Ragupathi, Govindaswami;
    • Danishefsky, Samuel J.;
    • Livingston, Philip O.;
    • Bornmann, William;
    • Spassova, Maria;
    • Zatorski, Andrzej;
    • Spriggs, David;
    • Aghajanian, Carol;
    • Soignet, Steven;
    • Peyton, Madeline;
    • O'Flaherty, Catherine;
    • Curtin, John;
    • Lloyd, Kenneth O.
    Publication type:
    Article
    12

    Patterns of genomic instability in > 2000 patients with ovarian cancer across six clinical trials evaluating olaparib.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01413-5
    By:
    • Barnicle, Alan;
    • Ray-Coquard, Isabelle;
    • Rouleau, Etienne;
    • Cadoo, Karen;
    • Simpkins, Fiona;
    • Aghajanian, Carol;
    • Leary, Alexandra;
    • Poveda, Andrés;
    • Lheureux, Stephanie;
    • Pujade-Lauraine, Eric;
    • You, Benoit;
    • Ledermann, Jonathan;
    • Matulonis, Ursula;
    • Gourley, Charlie;
    • Timms, Kirsten M.;
    • Lai, Zhongwu;
    • Hodgson, Darren R.;
    • Elks, Cathy E.;
    • Dearden, Simon;
    • Egile, Coumaran
    Publication type:
    Article
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    A phase I, open-label, two-stage study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the oral AKT inhibitor GSK2141795 in patients with solid tumors.

    Published in:
    Investigational New Drugs, 2018, v. 36, n. 6, p. 1016, doi. 10.1007/s10637-018-0591-z
    By:
    • Aghajanian, Carol;
    • Bell-McGuinn, Katherine M.;
    • Burris, Howard A.;
    • Siu, Lillian L.;
    • Stayner, Lee-Ann;
    • Wheler, Jennifer J.;
    • Hong, David S.;
    • Kurkjian, Carla;
    • Pant, Shubham;
    • Santiago-Walker, Ademi;
    • Gauvin, Jennifer L.;
    • Antal, Joyce M.;
    • Opalinska, Joanna B.;
    • Morris, Shannon R.;
    • Infante, Jeffrey R.
    Publication type:
    Article
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    Maintenance treatment with rucaparib for recurrent ovarian carcinoma in ARIEL3, a randomized phase 3 trial: The effects of best response to last platinum‐based regimen and disease at baseline on efficacy and safety.

    Published in:
    Cancer Medicine, 2021, v. 10, n. 20, p. 7162, doi. 10.1002/cam4.4260
    By:
    • Oaknin, Ana;
    • Oza, Amit M.;
    • Lorusso, Domenica;
    • Aghajanian, Carol;
    • Dean, Andrew;
    • Colombo, Nicoletta;
    • Weberpals, Johanne I.;
    • Clamp, Andrew R.;
    • Scambia, Giovanni;
    • Leary, Alexandra;
    • Holloway, Robert W.;
    • Amenedo Gancedo, Margarita;
    • Fong, Peter C.;
    • Goh, Jeffrey C.;
    • O'Malley, David M.;
    • Armstrong, Deborah K.;
    • Banerjee, Susana;
    • García‐Donas, Jesus;
    • Swisher, Elizabeth M.;
    • Cameron, Terri
    Publication type:
    Article
    20

    Phase 2 study of LY3023414 in patients with advanced endometrial cancer harboring activating mutations in the PI3K pathway.

    Published in:
    2020
    By:
    • Rubinstein, Maria M.;
    • Hyman, David M.;
    • Caird, Imogen;
    • Won, Helen;
    • Soldan, Krysten;
    • Seier, Kenneth;
    • Iasonos, Alexia;
    • Tew, William P.;
    • O'Cearbhaill, Roisin E.;
    • Grisham, Rachel N.;
    • Hensley, Martee L.;
    • Troso‐Sandoval, Tiffany;
    • Sabbatini, Paul;
    • Guillen, Joyce;
    • Selcuklu, S. Duygu;
    • Zimel, Catherine;
    • Torrisi, Jean;
    • Aghajanian, Carol;
    • Makker, Vicky;
    • Troso-Sandoval, Tiffany
    Publication type:
    journal article
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    Phase I Study of a Multivalent WT1 Peptide Vaccine (Galinpepimut-S) in Combination with Nivolumab in Patients with WT1-Expressing Ovarian Cancer in Second or Third Remission.

    Published in:
    Cancers, 2023, v. 15, n. 5, p. 1458, doi. 10.3390/cancers15051458
    By:
    • Manning-Geist, Beryl L.;
    • Gnjatic, Sacha;
    • Aghajanian, Carol;
    • Konner, Jason;
    • Kim, Sarah H.;
    • Sarasohn, Debra;
    • Soldan, Krysten;
    • Tew, William P.;
    • Sarlis, Nicholas J.;
    • Zamarin, Dmitriy;
    • Kravetz, Sara;
    • Laface, Ilaria;
    • Rasalan-Ho, Teresa;
    • Qi, Jingjing;
    • Wong, Phillip;
    • Sabbatini, Paul J.;
    • O'Cearbhaill, Roisin E.
    Publication type:
    Article
    27

    Machine learning-based prediction of microsatellite instability and high tumor mutation burden from contrast-enhanced computed tomography in endometrial cancers.

    Published in:
    Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-72475-9
    By:
    • Veeraraghavan, Harini;
    • Friedman, Claire F.;
    • DeLair, Deborah F.;
    • Ninčević, Josip;
    • Himoto, Yuki;
    • Bruni, Silvio G.;
    • Cappello, Giovanni;
    • Petkovska, Iva;
    • Nougaret, Stephanie;
    • Nikolovski, Ines;
    • Zehir, Ahmet;
    • Abu-Rustum, Nadeem R.;
    • Aghajanian, Carol;
    • Zamarin, Dmitriy;
    • Cadoo, Karen A.;
    • Diaz, Luis A.;
    • Leitao, Mario M.;
    • Makker, Vicky;
    • Soslow, Robert A.;
    • Mueller, Jennifer J.
    Publication type:
    Article
    28

    Phase II, 2‐stage, 2‐arm, PIK3CA mutation stratified trial of MK‐2206 in recurrent endometrial cancer.

    Published in:
    International Journal of Cancer, 2020, v. 147, n. 2, p. 413, doi. 10.1002/ijc.32783
    By:
    • Myers, Andrea P.;
    • Konstantinopoulos, Panagiotis A.;
    • Barry, William T.;
    • Luo, Weixiu;
    • Broaddus, Russell R.;
    • Makker, Vicky;
    • Drapkin, Ronny;
    • Liu, Joyce;
    • Doyle, Austin;
    • Horowitz, Neil S.;
    • Meric‐Bernstam, Funda;
    • Birrer, Michael;
    • Aghajanian, Carol;
    • Coleman, Robert L.;
    • Mills, Gordon B.;
    • Cantley, Lewis C.;
    • Matulonis, Ursula A.;
    • Westin, Shannon N.
    Publication type:
    Article
    29

    Tumor Inhibition by Enzalutamide in a Xenograft Model of Ovarian Cancer.

    Published in:
    Cancer Investigation, 2016, v. 34, n. 10, p. 517, doi. 10.1080/07357907.2016.1242598
    By:
    • Park, Brian Y.;
    • Grisham, Rachel N.;
    • den Hollander, Bjørnar;
    • Thapi, Dharmarao;
    • Berman, Tara;
    • de Stanchina, Elisa;
    • Zhou, Qin;
    • Iyer, Gopa;
    • Aghajanian, Carol;
    • Spriggs, David R.
    Publication type:
    Article
    30

    Better Therapeutic Trials in Ovarian Cancer.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 4, p. 1, doi. 10.1093/jnci/dju029
    By:
    • Bookman, Michael A.;
    • Gilks, C. Blake;
    • Kohn, Elise C.;
    • Kaplan, Karen O.;
    • Huntsman, David;
    • Aghajanian, Carol;
    • Birrer, Michael J.;
    • Ledermann, Jonathan A.;
    • Oza, Amit M.;
    • Swenerton, Kenneth D.
    Publication type:
    Article
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    Guidelines and selection criteria for secondary cytoreductive surgery in patients with recurrent, platinum‐sensitive epithelial ovarian carcinomaPresented at the 36th Annual Meeting of the Society of Gynecologic Oncologists, Miami Beach, Florida, March 19–23, 2005.

    Published in:
    Cancer (0008543X), 2006, v. 106, n. 9, p. 1933
    By:
    • Dennis S. Chi;
    • Kristina McCaughty;
    • John P. Diaz;
    • Jae Huh;
    • Sarah Schwabenbauer;
    • Amanda J. Hummer;
    • Ennapadam S. Venkatraman;
    • Carol Aghajanian;
    • Yukio Sonoda;
    • Nadeem R. Abu‐Rustum;
    • Richard R. Barakat
    Publication type:
    Article
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