Works by Aggarwal, Bharat B.

Results: 112

The Relationship Between Inflammation and Cancer Is Analogous to That Between Fuel and Fire.

Published in:

Oncology (08909091), 2011, v. 25, n. 5, p. 414

By:

AGGARWAL, BHARAT B.;
SUNG, BOKYUNG

Publication type:

Article

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon.

Published in:

Nature, 1985, v. 318, n. 6047, p. 665, doi. 10.1038/318665a0

By:

Aggarwal, Bharat B.;
Eessalu, Thomas E.;
Hass, Philip E.

Publication type:

Article

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity.

Published in:

Nature, 1984, v. 312, n. 5996, p. 721, doi. 10.1038/312721a0

By:

Gray, Patrick W.;
Aggarwal, Bharat B.;
Benton, Charles V.;
Bringman, Timothy S.;
Henzel, William J.;
Jarrett, Julie A.;
Leung, David W.;
Moffat, Barbara;
Ng, Peter;
Svedersky, Lloyd P.;
Palladino, Michael A.;
Nedwin, Glenn E.

Publication type:

Article

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin.

Published in:

Nature, 1984, v. 312, n. 5996, p. 724, doi. 10.1038/312724a0

By:

Pennica, Diane;
Nedwin, Glenn E.;
Hayflick, Joel S.;
Seeburg, Peter H.;
Derynck, Rik;
Palladino, Michael A.;
Kohr, William J.;
Aggarwal, Bharat B.;
Goeddel, David V.

Publication type:

Article

Signalling pathways of the TNF superfamily: a double-edged sword.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 9, p. 745, doi. 10.1038/nri1184

By:

Aggarwal, Bharat B.

Publication type:

Article

Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.02160

By:

Gupta, Subash Chandra;
Kunnumakkara, Ajaikumar B.;
Aggarwal, Sadhna;
Aggarwal, Bharat B.

Publication type:

Article

Characterization of human tumor necrosis factor produced by peripheral blood monocytes and its separation from lymphotoxin.

Published in:

International Journal of Cancer, 1985, v. 36, n. 1, p. 69, doi. 10.1002/ijc.2910360112

By:

Kelker, Hanna Chroboczek;
Oppenheim, Joel D.;
Stone-Wolff, Donna;
Henriksen-DeStefano, Dorothy;
Aggarwal, Bharat B.;
Stevenson, Henry C.;
Vilček, Jan

Publication type:

Article

Editorial: Balancing Tumor Necrosis Factor Receptor I and Tumor Necrosis Factor Receptor II Jointly for Joint Inflammation.

Published in:

Arthritis & Rheumatology, 2014, v. 66, n. 10, p. 2657, doi. 10.1002/art.38753

By:

Aggarwal, Bharat B.

Publication type:

Article

Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-κB and MAPK signalling.

Published in:

Cellular Microbiology, 2008, v. 10, n. 7, p. 1442, doi. 10.1111/j.1462-5822.2008.01137.x

By:

Iyer, Chandra;
Kosters, Astrid;
Sethi, Gautam;
Kunnumakkara, Ajaikumar B.;
Aggarwal, Bharat B.;
Versalovic, James

Publication type:

Article

Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family.

Published in:

Carcinogenesis, 2012, v. 33, n. 12, p. 2441, doi. 10.1093/carcin/bgs286

By:

Takahashi, Masanobu;
Sung, Bokyung;
Shen, Yan;
Hur, Keun;
Link, Alexander;
Boland, C. Richard;
Aggarwal, Bharat B.;
Goel, Ajay

Publication type:

Article

Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways.

Published in:

Carcinogenesis, 2011, v. 32, n. 9, p. 1372, doi. 10.1093/carcin/bgr032

By:

Prakobwong, Suksanti;
Gupta, Subash C.;
Kim, Ji Hye;
Sung, Bokyung;
Pinlaor, Porntip;
Hiraku, Yusuke;
Wongkham, Sopit;
Sripa, Banchob;
Pinlaor, Somchai;
Aggarwal, Bharat B.

Publication type:

Article

1′-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway.

Published in:

Carcinogenesis, 2011, v. 32, n. 6, p. 904, doi. 10.1093/carcin/bgr052

By:

Pang, Xiufeng;
Zhang, Li;
Lai, Li;
Chen, Jing;
Wu, Yuanyuan;
Yi, Zhengfang;
Zhang, Jian;
Qu, Weijing;
Aggarwal, Bharat B.;
Liu, Mingyao

Publication type:

Article

Nuclear Transcription Factor-kappaB in Hodgkin's Disease.

Published in:

Leukemia & Lymphoma, 2003, v. 44, n. 6, p. 929, doi. 10.1080/1042819031000067558

By:

Younes, Anas;
Garg, Amit;
Aggarwal, Bharat B.

Publication type:

Article

Serum Cytokine Levels in Infectious Mononucleosis at Diagnosis and Convalescence.

Published in:

Leukemia & Lymphoma, 1998, v. 30, n. 5/6, p. 583, doi. 10.3109/10428199809057570

By:

Wright-Browne, Vance;
Schnee, Amanda M.;
Jenkins, Mark A.;
Thall, Peter F.;
Aggarwal, Bharat B.;
Talpaz, Moshe;
Estrov, Zeev

Publication type:

Article

RANKL Signaling and Osteoclastogenesis Is Negatively Regulated by Cardamonin

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064118

By:

Sung, Bokyung;
Prasad, Sahdeo;
Yadav, Vivek R.;
Gupta, Subash C.;
Reuter, Simone;
Yamamoto, Norio;
Murakami, Akira;
Aggarwal, Bharat B.

Publication type:

Article

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031318

By:

Checker, Rahul;
Sandur, Santosh K.;
Sharma, Deepak;
Patwardhan, Raghavendra S.;
Jayakumar, S.;
Kohli, Vineet;
Sethi, Gautam;
Aggarwal, Bharat B.;
Sainis, Krishna B.

Publication type:

Article

Boswellic Acid Suppresses Growth and Metastasis of Human Pancreatic Tumors in an Orthotopic Nude Mouse Model through Modulation of Multiple Targets.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026943

By:

Park, Byoungduck;
Prasad, Sahdeo;
Yadav, Vivek;
Bokyung Sung;
Aggarwal, Bharat B.

Publication type:

Article

Epidermal growth factor down-regulates the expression of neutrophil gelatinase-associated lipocalin (NGAL) through E-cadherin in pancreatic cancer cells.

Published in:

Cancer (0008543X), 2011, v. 117, n. 11, p. 2408, doi. 10.1002/cncr.25803

By:

Zhimin Tong;
Chakraborty, Subhankar;
Bokyung Sung;
Koolwal, Pooja;
Kaur, Sukhwinder;
Aggarwal, Bharat B.;
Mani, Sendurai A.;
Bresalier, Robert S.;
Batra, Surinder K.;
Guha, Sushovan

Publication type:

Article

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases.

Published in:

2017

By:

Kunnumakkara, Ajaikumar B;
Bordoloi, Devivasha;
Padmavathi, Ganesan;
Monisha, Javadi;
Roy, Nand Kishor;
Prasad, Sahdeo;
Aggarwal, Bharat B

Publication type:

journal article

Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers.

Published in:

2013

By:

Aggarwal, Bharat B;
Gupta, Subash C;
Sung, Bokyung

Publication type:

journal article

Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers.

Published in:

British Journal of Pharmacology, 2013, v. 169, n. 8, p. 1672, doi. 10.1111/bph.12131

By:

Aggarwal, Bharat B;
Gupta, Subash C;
Sung, Bokyung

Publication type:

Article

Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 7, p. 2127, doi. 10.1111/j.1476-5381.2011.01702.x

By:

Reuter, Simone;
Gupta, Subash C;
Phromnoi, Kanokkarn;
Aggarwal, Bharat B

Publication type:

Article

Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 3, p. 741, doi. 10.1111/j.1476-5381.2011.01603.x

By:

Yadav, Vivek R;
Prasad, Sahdeo;
Aggarwal, Bharat B

Publication type:

Article

Curcumin.

Published in:

Cancer Biology & Therapy, 2011, v. 11, n. 2, p. 236, doi. 10.4161/cbt.11.2.14405

By:

Yadav, Vivek R.;
Aggarwal, Bharat B.

Publication type:

Article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.

Published in:

Autophagy, 2021, v. 17, n. 1, p. 1, doi. 10.1080/15548627.2020.1797280

By:

Klionsky, Daniel J.;
Abdel-Aziz, Amal Kamal;
Abdelfatah, Sara;
Abdellatif, Mahmoud;
Abdoli, Asghar;
Abel, Steffen;
Abeliovich, Hagai;
Abildgaard, Marie H.;
Abudu, Yakubu Princely;
Acevedo-Arozena, Abraham;
Adamopoulos, Iannis E.;
Adeli, Khosrow;
Adolph, Timon E.;
Adornetto, Annagrazia;
Aflaki, Elma;
Agam, Galila;
Agarwal, Anupam;
Aggarwal, Bharat B.;
Agnello, Maria;
Agostinis, Patrizia

Publication type:

Article

Nuclear factor-κB (nf-κB) is frequently expressed in lung cancer and preneoplastic lesions.

Published in:

Cancer (0008543X), 2006, v. 107, n. 11, p. 2637, doi. 10.1002/cncr.22315

By:

Tang, Ximing;
Liu, Diane;
Shishodia, Shishir;
Ozburn, Natalie;
Behrens, Carmen;
Lee, J. Jack;
Hong, Waun Ki;
Aggarwal, Bharat B.;
Wistuba, Ignacio I.

Publication type:

Article

Curcumin‐induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IκB kinase and nuclear factor κB activity and are independent of the B‐Raf/mitogen‐activated/extracellular signal‐regulated protein kinase pathway and the Akt pathway

Published in:

Cancer (0008543X), 2005, v. 104, n. 4, p. 879

By:

Doris R. Siwak;
Shishir Shishodia;
Bharat B. Aggarwal;
Razelle Kurzrock

Publication type:

Article

Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis.

Published in:

2004

By:

Li, Lan;
Aggarwal, Bharat B;
Shishodia, Shishir;
Abbruzzese, James;
Kurzrock, Razelle

Publication type:

journal article

Nuclear factor-?B and I?B kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis.

Published in:

Cancer (0008543X), 2004, v. 101, n. 10, p. 2351

By:

Lan Li;
Bharat B. Aggarwal;
Shishir Shishodia;
James Abbruzzese;
Razelle Kurzrock

Publication type:

Article

Chronic diseases, inflammation, and spices: how are they linked?

Published in:

2018

By:

Kunnumakkara, Ajaikumar B.;
Sailo, Bethsebie L.;
Banik, Kishore;
Harsha, Choudhary;
Prasad, Sahdeo;
Gupta, Subash Chandra;
Bharti, Alok Chandra;
Aggarwal, Bharat B.

Publication type:

journal article

Targeting cell signaling pathways for drug discovery: An old lock needs a new key.

Published in:

Journal of Cellular Biochemistry, 2007, v. 102, n. 3, p. 580, doi. 10.1002/jcb.21500

By:

Aggarwal, Bharat B.;
Sethi, Gautam;
Baladandayuthapani, Veera;
Krishnan, Sunil;
Shishodia, Shishir

Publication type:

Article

Effect of cell cycle on the regulation of the cell surface and secreted forms of type I and type II human tumor necrosis factor receptors.

Published in:

Journal of Cellular Biochemistry, 1995, v. 59, n. 3, p. 303, doi. 10.1002/jcb.240590303

By:

Pocsik, Eva;
Mihalik, Rudolf;
Penzes, Maria;
Loetscher, Hansruedi;
Gallati, Harald;
Aggarwal, Bharat B.

Publication type:

Article

Cell density-dependent regulation of cell surface expression of two types of human tumor necrosis factor receptors and its effect on cellular response.

Published in:

Journal of Cellular Biochemistry, 1994, v. 54, n. 4, p. 453, doi. 10.1002/jcb.240540412

By:

Pocsik, Eva;
Mihalik, Rudolf;
Ali-Osman, Francis;
Aggarwal, Bharat B.

Publication type:

Article

Obituary: Madhu Sudan Kanungo, PhD (1927–2011).

Published in:

2012

By:

Koul, Omanand;
Aggarwal, Bharat B.;
Rath, Pramod C.

Publication type:

Obituary

Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets.

Published in:

International Journal of Cancer, 2012, v. 131, n. 3, p. E292, doi. 10.1002/ijc.26442

By:

Kunnumakkara, Ajaikumar B.;
Sung, Bokyung;
Ravindran, Jayaraj;
Diagaradjane, Parmeswaran;
Deorukhkar, Amit;
Dey, Sanjit;
Koca, Cemile;
Tong, Zhimin;
Gelovani, Juri G.;
Guha, Sushovan;
Krishnan, Sunil;
Aggarwal, Bharat B.

Publication type:

Article

Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers.

Published in:

International Journal of Cancer, 2012, v. 130, n. 9, p. 2176, doi. 10.1002/ijc.26251

By:

Yadav, Vivek R.;
Prasad, Sahdeo;
Sung, Bokyung;
Gelovani, Juri G.;
Guha, Sushovan;
Krishnan, Sunil;
Aggarwal, Bharat B.

Publication type:

Article

Butein, a tetrahydroxychalcone, suppresses cancer-induced osteoclastogenesis through inhibition of receptor activator of nuclear factor-kappaB ligand signaling.

Published in:

International Journal of Cancer, 2011, v. 129, n. 9, p. 2062, doi. 10.1002/ijc.25868

By:

Sung, Bokyung;
Cho, Sung-Gook;
Liu, Mingyao;
Aggarwal, Bharat B.

Publication type:

Article

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.

Published in:

International Journal of Cancer, 2011, v. 129, n. 1, p. 88, doi. 10.1002/ijc.25656

By:

Prakobwong, Suksanti;
Khoontawad, Jarinya;
Yongvanit, Puangrat;
Pairojkul, Chawalit;
Hiraku, Yusuke;
Sithithaworn, Paiboon;
Pinlaor, Porntip;
Aggarwal, Bharat B.;
Pinlaor, Somchai

Publication type:

Article

Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression.

Published in:

International Journal of Cancer, 2011, v. 129, n. 1, p. 23, doi. 10.1002/ijc.25966

By:

Park, Byoungduck;
Sung, Bokyung;
Yadav, Vivek R.;
Cho, Sung-Gook;
Liu, Mingyao;
Aggarwal, Bharat B.

Publication type:

Article

Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.

Published in:

International Journal of Cancer, 2010, v. 127, n. 2, p. 257, doi. 10.1002/ijc.25041

By:

Harikumar, Kuzhuvelil B.;
Kunnumakkara, Ajaikumar B.;
Sethi, Gautam;
Diagaradjane, Parmeswaran;
Anand, Preetha;
Pandey, Manoj K.;
Gelovani, Juri;
Krishnan, Sunil;
Guha, Sushovan;
Aggarwal, Bharat B.

Publication type:

Article

Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.

Published in:

International Journal of Cancer, 2010, v. 127, n. 2, p. 282, doi. 10.1002/ijc.25059

By:

Pandey, Manoj K.;
Sung, Bokyung;
Aggarwal, Bharat B.

Publication type:

Article

Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.

Published in:

International Journal of Cancer, 2009, v. 125, n. 9, p. 2187, doi. 10.1002/ijc.24593

By:

Kunnumakkara, Ajaikumar B.;
Diagaradjane, Parmeswaran;
Anand, Preetha;
Kuzhuvelil, Harikumar B.;
Deorukhkar, Amit;
Gelovani, Juri;
Guha, Sushovan;
Krishnan, Sunil;
Aggarwal, Bharat B.

Publication type:

Article

Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-κB ligand through modulation of NF-κB pathway.

Published in:

International Journal of Cancer, 2008, v. 123, n. 8, p. 1733, doi. 10.1002/ijc.23745

By:

Ahn, Kwang Seok;
Sethi, Gautam;
Chaturvedi, Madan M.;
Aggarwal, Bharat B.

Publication type:

Article

Expression of NF-κB parallels COX-2 expression in oral precancer and cancer: Association with smokeless tobacco.

Published in:

International Journal of Cancer, 2007, v. 120, n. 12, p. 2545, doi. 10.1002/ijc.22657

By:

Sawhney, Meenakshi;
Rohatgi, Nidhi;
Kaur, Jatinder;
Shishodia, Shishir;
Sethi, Gautam;
Gupta, Siddhartha D.;
Deo, Suryanaryana V. S.;
Shukla, Nootan K.;
Aggarwal, Bharat B.;
Ralhan, Ranju

Publication type:

Article

Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0186993

By:

Buhrmann, Constanze;
Popper, Bastian;
Aggarwal, Bharat B.;
Shakibaei, Mehdi

Publication type:

Article

Is curcumin bioavailability a problem in humans: lessons from clinical trials.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2019, v. 15, n. 9, p. 705, doi. 10.1080/17425255.2019.1650914

By:

Kunnumakkara, Ajaikumar B.;
Harsha, Choudhary;
Banik, Kishore;
Vikkurthi, Rajesh;
Sailo, Bethsebie L.;
Bordoloi, Devivasha;
Gupta, Subash C.;
Aggarwal, Bharat B.

Publication type:

Article

Resveratrol addiction: To die or not to die.

Published in:

Molecular Nutrition & Food Research, 2009, v. 53, n. 1, p. 115, doi. 10.1002/mnfr.200800148

By:

Shakibaei, Mehdi;
Harikumar, Kuzhuvelil B.;
Aggarwal, Bharat B.

Publication type:

Article

Multi-targeted therapy by curcumin: how spicy is it?

Published in:

Molecular Nutrition & Food Research, 2008, v. 52, n. 9, p. 1010, doi. 10.1002/mnfr.200700354

By:

Goel, Ajay;
Jhurani, Sonia;
Aggarwal, Bharat B.

Publication type:

Article

Targeting Inflammatory Pathways by Dietary Agents For Prevention and Therapy of Cancer.

Published in:

Journal of Food & Drug Analysis, 2012, v. 20, p. 231

By:

Bharat B. Aggarwal;
Sahdeo Prasad;
Vivek R. Yadav;
Byoungduck Park;
Ji Hye Kim;
Subash C. Gupta;
Seong Woo Yoon;
Afsaneh Lavasanifar;
Bokyung Sung

Publication type:

Article

Adenosine suppresses activation of nuclear factor-?B selectively induced by tumor necrosis factor in different cell types.

Published in:

Oncogene, 2003, v. 22, n. 8, p. 1206, doi. 10.1038/sj.onc.1206184

By:

Majumdar, Sekhar;
Aggarwal, Bharat B

Publication type:

Article