Works by Agar, Nathalie

Results: 35

Predicting Prostate Cancer Directly from Tissue Images using Deep Learning on Mass Spectrometry Imaging and Whole Slide Imaging Data.
Published in:
2022
By:
- Haque, Md Inzamam Ul;
- Mukherjee, Debangshu;
- Stopka, Sylwia A.;
- Agar, Nathalie Y.R.;
- Hinkle, Jacob;
- Ovchinnikova, Olga S.
Publication type:
Abstract
Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00318-5
By:
- Basu, Sankha S.;
- Stopka, Sylwia A.;
- Abdelmoula, Walid M.;
- Randall, Elizabeth C.;
- Gimenez-Cassina Lopez, Begoña;
- Regan, Michael S.;
- Calligaris, David;
- Lu, Fake F.;
- Norton, Isaiah;
- Mallory, Melissa A.;
- Santagata, Sandro;
- Dillon, Deborah A.;
- Golshan, Mehra;
- Agar, Nathalie Y. R.
Publication type:
Article
Unique Intradural Inflammatory Mass Containing Precipitated Morphine: Confirmatory Analysis by LESA‐MS and MALDI‐MS.
Published in:
2018
By:
- Kim, Alexander J.;
- Basu, Sankha;
- Glass, Carolyn;
- Ross, Edgar L.;
- Agar, Nathalie;
- He, Qing;
- Calligaris, David
Publication type:
Case Study
Mass spectrometry methods and mathematical PK/PD model for decision tree-guided covalent drug development.
Published in:
Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56985-6
By:
- Hossain, Md Amin;
- Brahme, Rutali R.;
- Miller, Brandon C.;
- Amin, Jakal;
- de Barros, Marcela;
- Schneider, Jaime L.;
- Auclair, Jared R.;
- Mattos, Carla;
- Wang, Qingping;
- Agar, Nathalie Y. R.;
- Greenblatt, David J.;
- Manetsch, Roman;
- Agar, Jeffrey N.
Publication type:
Article
Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics.
Published in:
Nature Protocols, 2018, v. 13, n. 12, p. 2827, doi. 10.1038/s41596-018-0066-x
By:
- Bergmann, Sonja;
- Lawler, Sean E.;
- Qu, Yuan;
- Fadzen, Colin M.;
- Wolfe, Justin M.;
- Regan, Michael S.;
- Pentelute, Bradley L.;
- Agar, Nathalie Y. R.;
- Cho, Choi-Fong
Publication type:
Article
Discrimination of Human Astrocytoma Subtypes by Lipid Analysis Using Desorption Electrospray Ionization Imaging Mass Spectrometry.
Published in:
Angewandte Chemie International Edition, 2010, v. 49, n. 34, p. 5953, doi. 10.1002/anie.201001452
By:
- Eberlin, Livia S.;
- Dill, Allison L.;
- Golby, Alexandra J.;
- Ligon, Keith L.;
- Wiseman, Justin M.;
- Cooks, R. Graham;
- Agar, Nathalie Y. R.
Publication type:
Article
Mass spectrometry imaging as a tool for surgical decision-making.
Published in:
Journal of Mass Spectrometry, 2013, v. 48, n. 11, p. 1178, doi. 10.1002/jms.3295
By:
- Calligaris, David;
- Norton, Isaiah;
- Feldman, Daniel R.;
- Ide, Jennifer L.;
- Dunn, Ian F.;
- Eberlin, Livia S.;
- Graham Cooks, R.;
- Jolesz, Ferenc A.;
- Golby, Alexandra J.;
- Santagata, Sandro;
- Agar, Nathalie Y.
Publication type:
Article
massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation.
Published in:
Bioinformatics, 2022, v. 38, n. 7, p. 2015, doi. 10.1093/bioinformatics/btac032
By:
- Abdelmoula, Walid M;
- Stopka, Sylwia A;
- Randall, Elizabeth C;
- Regan, Michael;
- Agar, Jeffrey N;
- Sarkaria, Jann N;
- Wells, William M;
- Kapur, Tina;
- Agar, Nathalie Y R
Publication type:
Article
Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022.
Published in:
Clinical Breast Cancer, 2020, v. 20, n. 2, p. 145, doi. 10.1016/j.clbc.2019.07.011
By:
- Freedman, Rachel A.;
- Gelman, Rebecca S.;
- Agar, Nathalie Y. R.;
- Santagata, Sandro;
- Randall, Elizabeth C.;
- Lopez, Begona Gimenez-Cassina;
- Connolly, Roisin M.;
- Dunn, Ian F.;
- Van Poznak, Catherine H.;
- Aitders, Carey K.;
- Melisko, Michelle E.;
- Silvestri, Kelly;
- Cotter, Christine M.;
- Componeschi, Kathryn P.;
- Marte, Juan M.;
- Moy, Beverly;
- Blackwell, Kimberly L.;
- Puhalla, Shannon L.;
- Ibrahim, Nuhad;
- Moynihan, Timothy J.
Publication type:
Article
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32430-w
By:
- Coy, Shannon;
- Wang, Shu;
- Stopka, Sylwia A.;
- Lin, Jia-Ren;
- Yapp, Clarence;
- Ritch, Cecily C.;
- Salhi, Lisa;
- Baker, Gregory J.;
- Rashid, Rumana;
- Baquer, Gerard;
- Regan, Michael;
- Khadka, Prasidda;
- Cole, Kristina A.;
- Hwang, Jaeho;
- Wen, Patrick Y.;
- Bandopadhayay, Pratiti;
- Santi, Mariarita;
- De Raedt, Thomas;
- Ligon, Keith L.;
- Agar, Nathalie Y. R.
Publication type:
Article
Peak learning of mass spectrometry imaging data using artificial neural networks.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25744-8
By:
- Abdelmoula, Walid M.;
- Lopez, Begona Gimenez-Cassina;
- Randall, Elizabeth C.;
- Kapur, Tina;
- Sarkaria, Jann N.;
- White, Forest M.;
- Agar, Jeffrey N.;
- Wells, William M.;
- Agar, Nathalie Y. R.
Publication type:
Article
Protein Aggregation and Protein Instability Govern Familial Amyotrophic Lateral Sclerosis Patient Survival.
Published in:
PLoS Biology, 2008, v. 6, n. 7, p. e170, doi. 10.1371/journal.pbio.0060170
By:
- Wang, Qi;
- Johnson, Joshua L.;
- Agar, Nathalie Y. R;
- Agar, Jeffrey N.
Publication type:
Article
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
Published in:
Proteomics, 2014, v. 14, n. 10, p. 1152, doi. 10.1002/pmic.201300450
By:
- Auclair, Jared R.;
- Salisbury, Joseph P.;
- Johnson, Joshua L.;
- Petsko, Gregory A.;
- Ringe, Dagmar;
- Bosco, Daryl A.;
- Agar, Nathalie Y. R.;
- Santagata, Sandro;
- Durham, Heather D.;
- Agar, Jeffrey N.
Publication type:
Article
Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging.
Published in:
Scientific Reports, 2013, p. 1, doi. 10.1038/srep02859
By:
- Xiaohui Liu;
- Ide, Jennifer L.;
- Norton, Isaiah;
- Marchionni, Mark A.;
- Ebling, Maritza C.;
- Lan Y. Wang;
- Davis, Erin;
- Sauvageot, Claire M.;
- Kesari, Santosh;
- Kellersberger, Katherine A.;
- Easterling, Michael L.;
- Santagata, Sandro;
- Stuart, Darrin D.;
- Alberta, John;
- Agar, Jeffrey N.;
- Stiles, Charles D.;
- Agar, Nathalie Y. R.
Publication type:
Article
Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15623, doi. 10.1038/ncomms15623
By:
- Cho, Choi-Fong;
- Wolfe, Justin M.;
- Fadzen, Colin M.;
- Calligaris, David;
- Hornburg, Kalvis;
- Chiocca, E. Antonio;
- Agar, Nathalie Y. R.;
- Pentelute, Bradley L.;
- Lawler, Sean E.
Publication type:
Article
Multimodal imaging for improved diagnosis and treatment of cancers.
Published in:
Cancer (0008543X), 2015, v. 121, n. 6, p. 817, doi. 10.1002/cncr.29012
By:
- Tempany, Clare M. C.;
- Jayender, Jagadeesan;
- Kapur, Tina;
- Bueno, Raphael;
- Golby, Alexandra;
- Agar, Nathalie;
- Jolesz, Ferenc A.
Publication type:
Article
A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma.
Published in:
Neuro-Oncology, 2019, v. 21, n. 9, p. 1150, doi. 10.1093/neuonc/noz089
By:
- Pak, Ekaterina;
- MacKenzie, Ethan L;
- Zhao, Xuesong;
- Pazyra-Murphy, Maria F;
- Park, Paul M C;
- Wu, Lei;
- Shaw, Daniel L;
- Addleson, Emily C;
- Cayer, Suzanne S;
- Lopez, Begoña G-C;
- Agar, Nathalie Y R;
- Rubin, Lee L;
- Qi, Jun;
- Merk, Daniel J;
- Segal, Rosalind A
Publication type:
Article
ACTR-14. PHASE I STUDY OF AZD1775 WITH RADIATION THERAPY (RT) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM) AND EVALUATION OF INTRATUMORAL DRUG DISTRIBUTION (IDD) IN PATIENTS WITH RECURRENT GBM.
Published in:
Neuro-Oncology, 2018, v. 20, p. vi13, doi. 10.1093/neuonc/noy148.048
By:
- Alexander, Brian;
- Supko, Jeffrey;
- Agar, Nathalie;
- Ahluwalia, Manmeet;
- Desai, Arati;
- Dietrich, Jorg;
- Kaley, Thomas;
- Peereboom, David;
- Takebe, Naoko;
- Desideri, Serena
Publication type:
Article
Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data.
Published in:
Neuro-Oncology, 2018, v. 20, n. 2, p. 184, doi. 10.1093/neuonc/nox175
By:
- Sarkaria, Jann N.;
- Hu, Leland S.;
- Parney, Ian F.;
- Pafundi, Deanna H.;
- Brinkmann, Debra H.;
- Laack, Nadia N.;
- Giannini, Caterina;
- Burns, Terence C.;
- Kizilbash, Sani H.;
- Laramy, Janice K.;
- Swanson, Kristin R.;
- Kaufmann, Timothy J.;
- Brown, Paul D.;
- Agar, Nathalie Y. R.;
- Galanis, Evanthia;
- Buckner, Jan C.;
- Elmquist, William F.
Publication type:
Article
A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.
Published in:
Neuro-Oncology, 2017, v. 19, n. 6, p. 774, doi. 10.1093/neuonc/now261
By:
- Yu Sun;
- Alberta, John A.;
- Pilarz, Catherine;
- Calligaris, David;
- Chadwick, Emily J.;
- Ramkissoon, Shakti H.;
- Ramkissoon, Lori A.;
- Garcia, Veronica Matia;
- Mazzola, Emanuele;
- Goumnerova, Liliana;
- Kane, Michael;
- Zhan Yao;
- Kieran, Mark W.;
- Ligon, Keith L.;
- Hahn, William C.;
- Garraway, Levi A.;
- Rosen, Neal;
- Gray, Nathanael S.;
- Agar, Nathalie Y.;
- Buhrlage, Sara J.
Publication type:
Article
Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy.
Published in:
Science Translational Medicine, 2013, v. 5, n. 201, p. 1, doi. 10.1126/scitranslmed.3005954
By:
- Minbiao Ji;
- Orringer, Daniel A.;
- Freudiger, Christian W.;
- Ramkissoon, Shakti;
- Xiaohui Liu;
- Lau, Darryl;
- Golby, Alexandra J.;
- Norton, Isaiah;
- Hayashi, Marika;
- Agar, Nathalie Y. R.;
- Young, Geoffrey S.;
- Spino, Cathie;
- Santagata, Sandro;
- Camelo-Piragua, Sandra;
- Ligon, Keith L.;
- Sagher, Oren;
- Xie, X. Sunney
Publication type:
Article
Rapid discrimination of pediatric brain tumors by mass spectrometry imaging.
Published in:
Journal of Neuro-Oncology, 2018, v. 140, n. 2, p. 269, doi. 10.1007/s11060-018-2978-2
By:
- Clark, Amanda R.;
- Calligaris, David;
- Regan, Michael S.;
- Pomeranz Krummel, Daniel;
- Agar, Jeffrey N.;
- Kallay, Laura;
- MacDonald, Tobey;
- Schniederjan, Matthew;
- Santagata, Sandro;
- Pomeroy, Scott L.;
- Agar, Nathalie Y. R.;
- Sengupta, Soma
Publication type:
Article
Subjective Fatigue, Mental Effort, and Attention Deficits After Severe Traumatic Brain Injury.
Published in:
Neurorehabilitation & Neural Repair, 2009, v. 23, n. 9, p. 939, doi. 10.1177/1545968309340327
By:
- Belmont, Angelique;
- Agar, Nathalie;
- Azouvi, Philippe
Publication type:
Article
Genomic profile of human meningioma cell lines.
Published in:
PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0178322
By:
- Mei, Yu;
- Bi, Wenya Linda;
- Greenwald, Noah F.;
- Agar, Nathalie Y.;
- Beroukhim, Rameen;
- Dunn, Gavin P.;
- Dunn, Ian F.
Publication type:
Article
DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology.
Published in:
Neuro-Oncology, 2024, v. 26, n. 8, p. 1367, doi. 10.1093/neuonc/noae072
By:
- Rahman, Rifaquat;
- Shi, Diana D;
- Reitman, Zachary J;
- Hamerlik, Petra;
- Groot, John F de;
- Haas-Kogan, Daphne A;
- D'Andrea, Alan D;
- Sulman, Erik P;
- Tanner, Kirk;
- Agar, Nathalie Y R;
- Sarkaria, Jann N;
- Tinkle, Christopher L;
- Bindra, Ranjit S;
- Mehta, Minesh P;
- Wen, Patrick Y
Publication type:
Article
Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC-ESI-MS-MS.
Published in:
Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 20, p. 5989, doi. 10.1007/s00216-015-8803-2
By:
- Kertesz, Vilmos;
- Calligaris, David;
- Feldman, Daniel;
- Changelian, Armen;
- Laws, Edward;
- Santagata, Sandro;
- Agar, Nathalie;
- Berkel, Gary
Publication type:
Article
Discrimination of Human Astrocytoma Subtypes by Lipid Analysis Using Desorption Electrospray Ionization Imaging Mass Spectrometry.
Published in:
Angewandte Chemie, 2010, v. 122, n. 34, p. 6089, doi. 10.1002/ange.201001452
By:
- Eberlin, Livia S.;
- Dill, Allison L.;
- Golby, Alexandra J.;
- Ligon, Keith L.;
- Wiseman, Justin M.;
- Cooks, R. Graham;
- Agar, Nathalie Y. R.
Publication type:
Article
Rapid MALDI mass spectrometry imaging for surgical pathology.
Published in:
NPJ Precision Oncology, 2019, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41698-019-0089-y
By:
- Basu, Sankha S.;
- Regan, Michael S.;
- Randall, Elizabeth C.;
- Abdelmoula, Walid M.;
- Clark, Amanda R.;
- Gimenez-Cassina Lopez, Begoña;
- Cornett, Dale S.;
- Haase, Andreas;
- Santagata, Sandro;
- Agar, Nathalie Y. R.
Publication type:
Article
Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers.
Published in:
PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0261803
By:
- Stopka, Sylwia A.;
- van der Reest, Jiska;
- Abdelmoula, Walid M.;
- Ruiz, Daniela F.;
- Joshi, Shakchhi;
- Ringel, Alison E.;
- Haigis, Marcia C.;
- Agar, Nathalie Y. R.
Publication type:
Article
Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells.
Published in:
EMBO Molecular Medicine, 2012, v. 4, n. 9, p. 952, doi. 10.1002/emmm.201101094
By:
- Rodriguez, Noah;
- Yang, Junzheng;
- Hasselblatt, Kathleen;
- Liu, Shubai;
- Zhou, Yilan;
- Rauh-Hain, Jose A.;
- Ng, Shu-Kay;
- Choi, Pui-Wah;
- Fong, Wing-Ping;
- Agar, Nathalie Y. R.;
- Welch, William R.;
- Berkowitz, Ross S.;
- Ng, Shu-Wing
Publication type:
Article
The dentate gyrus differentially metabolizes glucose and alternative fuels during rest and stimulation.
Published in:
Journal of Neurochemistry, 2024, v. 168, n. 5, p. 533, doi. 10.1111/jnc.16004
By:
- York, Elisa M.;
- Miller, Anne;
- Stopka, Sylwia A.;
- Martínez-François, Juan Ramón;
- Hossain, Md Amin;
- Baquer, Gerard;
- Regan, Michael S.;
- Agar, Nathalie Y. R.;
- Yellen, Gary
Publication type:
Article
Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling.
Published in:
Cell Communication & Signaling, 2017, v. 15, p. 1, doi. 10.1186/s12964-017-0189-7
By:
- Yu Mei;
- Ziming Du;
- Changchen Hu;
- Greenwald, Noah F.;
- Abedalthagafi, Malak;
- Agar, Nathalie Y. R.;
- Dunn, Gavin P.;
- Bi, Wenya Linda;
- Santagata, Sandro;
- Dunn, Ian F.
Publication type:
Article
WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models.
Published in:
Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad066
By:
- Conage-Pough, Jason E;
- Stopka, Sylwia A;
- Oh, Ju-Hee;
- Mladek, Ann C;
- Burgenske, Danielle M;
- Regan, Michael S;
- Baquer, Gerard;
- Decker, Paul A;
- Carlson, Brett L;
- Bakken, Katrina K;
- Zhang, Jinqiang;
- Liu, Lily;
- Sun, Claire;
- Mu, Zhihua;
- Zhong, Wei;
- Tran, Nhan L;
- Elmquist, William F;
- Agar, Nathalie Y R;
- Sarkaria, Jann N;
- White, Forest M
Publication type:
Article
Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts.
Published in:
Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac130
By:
- Porath, Kendra A.;
- Regan, Michael S.;
- Griffith, Jessica I.;
- Jain, Sonia;
- Stopka, Sylwia A.;
- Burgenske, Danielle M.;
- Bakken, Katrina K.;
- Carlson, Brett L.;
- Decker, Paul A.;
- Vaubel, Rachael A.;
- Dragojevic, Sonja;
- Mladek, Ann C.;
- Connors, Margaret A.;
- Zeng Hu;
- Lihong He;
- Kitange, Gaspar J.;
- Gupta, Shiv K.;
- Feldsien, Thomas M.;
- Lefebvre, Didier R.;
- Agar, Nathalie Y. R.
Publication type:
Article
Structural Characterization of Pandoraea pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0052550
By:
- Colbert, Christopher L.;
- Agar, Nathalie Y. R.;
- Kumar, Pravindra;
- Chakko, Mathew N.;
- Sinha, Sangita C.;
- Powlowski, Justin B.;
- Eltis, Lindsay D.;
- Bolin, Jeffrey T.
Publication type:
Article