Works by Affara, Nabeel A.

Results: 56

The Multicopy Gene Sly Represses the Sex Chromosomesin the Male Mouse Germline after Meiosis.

Published in:

PLoS Biology, 2009, v. 7, n. 11, p. 1, doi. 10.1371/journal.pbio.1000244

By:

Cocquet, Julie;
Ellis, Peter J. I.;
Yamauchi, Yasuhiro;
Mahadevaiah, Shantha K.;
Affara, Nabeel A.;
Ward, Monika A.;
Burgoyne, Paul S.

Publication type:

Article

Correction: A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse.

Published in:

2019

By:

Cocquet, Julie;
Ellis, Peter J. I.;
Mahadevaiah, Shantha K.;
Affara, Nabeel A.;
Vaiman, Daniel;
Burgoyne, Paul S.

Publication type:

Correction Notice

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling.

Published in:

Frontiers in Physiology, 2019, p. 1, doi. 10.3389/fphys.2019.01278

By:

Rathje, Claudia C.;
Randle, Suzanne J.;
Al Rawi, Sara;
Skinner, Benjamin M.;
Nelson, David E.;
Majumdar, Antara;
Johnson, Emma E. P.;
Bacon, Joanne;
Vlazaki, Myrto;
Affara, Nabeel A.;
Ellis, Peter J.;
Laman, Heike

Publication type:

Article

Expansion of the HSFY gene family in pig lineages.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1650-x

By:

Skinner, Benjamin M.;
Lachani, Kim;
Sargent, Carole A.;
Fengtang Yang;
Ellis, Peter;
Hunt, Toby;
Beiyuan Fu;
Louzada, Sandra;
Churcher, Carol;
Tyler-Smith, Chris;
Affara, Nabeel A.

Publication type:

Article

Expansion of the HSFY gene family in pig lineages

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 442, doi. 10.1186/s12864-015-1650-x

By:

Skinner, Benjamin M;
Lachani, Kim;
Sargent, Carole A;
Fengtang Yang;
Ellis, Peter;
Hunt, Toby;
Fu, Beiyuan;
Louzada, Sandra;
Churcher, Carol;
Tyler-Smith, Chris;
Affara, Nabeel A

Publication type:

Article

Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-49

By:

Ellis, Peter J. I.;
Morris, Tiffany J.;
Skinner, Benjamin M.;
Sargent, Carole A.;
Vickers, Mark H.;
Gluckman, Peter D.;
Gilmour, Stewart;
Affara, Nabeel A.

Publication type:

Article

Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds.

Published in:

BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-784

By:

Fowler, Katie E.;
Pong-Wong, Ricardo;
Bauer, Julien;
Clemente, Emily J.;
Reitter, Christopher P.;
Affara, Nabeel A.;
Waite, Stephen;
Walling, Grant A.;
Griffin, Darren K.

Publication type:

Article

The role of the Y chromosome in male infertility.

Published in:

Expert Reviews in Molecular Medicine, 2001, v. 3, n. 3, p. 1, doi. 10.1017/S1462399401002319

By:

Affara, Nabeel A.

Publication type:

Article

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 2, p. 351, doi. 10.1093/hmg/ddz192

By:

Ellis, Peter J I;
Clemente, Emily J;
Ball, Penny;
Touré, Aminata;
Ferguson, Lydia;
Turner, James M A;
Loveland, Kate L;
Affara, Nabeel A;
Burgoyne, Paul S

Publication type:

Article

The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis.

Published in:

BMC Molecular Biology, 2010, v. 11, p. 33, doi. 10.1186/1471-2199-11-33

By:

Lopes, Alexandra M.;
Miguel, Ricardo N.;
Sargent, Carole A.;
Ellis, Peter J.;
Amorim, António;
Affara, Nabeel A.

Publication type:

Article

Germline mutations in the Von Hippel-Lindau disease ( VHL) gene in families from North America, Europe, and Japan.

Published in:

Human Mutation, 1996, v. 8, n. 4, p. 348, doi. 10.1002/(SICI)1098-1004(1996)8:4<348::AID-HUMU8>3.0.CO;2-3

By:

Zbar, Berton;
Kishida, Takeshi;
Chen, Fan;
Schmidt, Laura;
Maher, Eamonn R.;
Richards, Frances M.;
Crossey, Paul A.;
Webster, Andrew R.;
Affara, Nabeel A.;
Ferguson-Smith, Malcolm A.;
Brauch, Hiltrud;
Glavac, Damjan;
Neumann, Hartmut P.H.;
Tisherman, Sam;
Mulvihill, John J.;
Gross, David J.;
Shuin, Taro;
Whaley, Jean;
Seizinger, Berndt;
Kley, Nickolai

Publication type:

Article

Regions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region.

Published in:

BMC Genetics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2156-14-3

By:

Skinner, Benjamin M;
Lachani, Kim;
Sargent, Carole A;
Affara, Nabeel A

Publication type:

Article

Spermatogenesis and sex chromosome gene content: An evolutionary perspective.

Published in:

Human Fertility, 2006, v. 9, n. 1, p. 1, doi. 10.1080/14647270500230114

By:

Ellis, Peter J. I.;
Affara, Nabeel A.

Publication type:

Article

Inactivation of the von Hippel-Lindau ( VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: Evidence for a VHL-independent pathway in clear cell renal tumourigenesis.

Published in:

Genes, Chromosomes & Cancer, 1998, v. 22, n. 3, p. 200, doi. 10.1002/(SICI)1098-2264(199807)22:3<200::AID-GCC5>3.0.CO;2-#

By:

Clifford, Steven C.;
Prowse, Amanda H.;
Affara, Nabeel A.;
Buys, Charles H. C. M.;
Maher, Eamonn R.

Publication type:

Article

Sex and the single Y.

Published in:

BioEssays, 1991, v. 13, n. 9, p. 475, doi. 10.1002/bies.950130908

By:

Affara, Nabeel A.

Publication type:

Article

Karyomapping-a comprehensive means of simultaneous monogenic and cytogenetic PGD: comparison with standard approaches in real time for Marfan syndrome.

Published in:

2015

By:

Thornhill, Alan;
Handyside, Alan;
Ottolini, Christian;
Natesan, Senthil;
Taylor, Jon;
Sage, Karen;
Harton, Gary;
Cliffe, Kerry;
Affara, Nabeel;
Konstantinidis, Michalis;
Wells, Dagan;
Griffin, Darren

Publication type:

Report

Resource and hardware options for microarray-based experimentation.

Published in:

Briefings in Functional Genomics & Proteomics, 2003, v. 2, n. 1, p. 7, doi. 10.1093/bfgp/2.1.7

By:

Affara, Nabeel A.

Publication type:

Article

An algorithm for determining the origin of trisomy and the positions of chiasmata from SNP genotype data.

Published in:

Chromosome Research, 2011, v. 19, n. 2, p. 155, doi. 10.1007/s10577-010-9181-4

By:

Gabriel, Alem;
Hassold, Terry;
Thornhill, Alan;
Affara, Nabeel;
Handyside, Alan;
Griffin, Darren

Publication type:

Article

Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in the Gambia.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 9, p. 2086, doi. 10.1093/hmg/dds026

By:

Khulan, Batbayar;
Cooper, Wendy N.;
Skinner, Benjamin M.;
Bauer, Julien;
Owens, Stephen;
Prentice, Andrew M.;
Belteki, Gusztav;
Constancia, Miguel;
Dunger, David;
Affara, Nabeel A.

Publication type:

Article

Association of Sly with sex-linked gene amplification during mouse evolution: a side effect of genomic conflict in spermatids?

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 3010, doi. 10.1093/hmg/ddr204

By:

Ellis, Peter J.I.;
Bacon, Joanne;
Affara, Nabeel A.

Publication type:

Article

Transcriptional Profiling of Rats Subjected to Gestational Undernourishment: Implications for the Developmental Variations in Metabolic Traits.

Published in:

PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0007271

By:

Morris, Tiffany J.;
Vickers, Mark;
Gluckman, Peter;
Gilmour, Stewart;
Affara, Nabeel

Publication type:

Article

Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology.

Published in:

PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006524

By:

Ramos, Antonio M.;
Crooijmans, Richard P. M. A.;
Affara, Nabeel A.;
Amaral, Andreia J.;
Archibald, Alan L.;
Beever, Jonathan E.;
Bendixen, Christian;
Churcher, Carol;
Clark, Richard;
Dehais, Patrick;
Hansen, Mark S.;
Hedegaard, Jakob;
Zhi-Liang Hu;
Kerstens, Hindrik H.;
Law, Andy S.;
Megens, Hendrik-Jan;
Milan, Denis;
Nonneman10, Danny J.;
Rohrer, Gary A.;
Rothschild, Max F.

Publication type:

Article

Origin and phylogenetic status of the local Ashanti Dwarf pig (ADP) of Ghana based on genetic analysis.

Published in:

BMC Genomics, 2017, v. 18, p. 1, doi. 10.1186/s12864-017-3536-6

By:

Osei-Amponsah, Richard;
Skinner, Benjamin M.;
Adjei, Dennis O.;
Bauer, Julien;
Larson, Greger;
Affara, Nabeel A.;
Sargent, Carole A.

Publication type:

Article

A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse.

Published in:

PLoS Genetics, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pgen.1002900

By:

Cocquet, Julie;
Ellis, Peter J. I.;
Mahadevaiah, Shantha K.;
Affara, Nabeel A.;
Vaiman, Daniel;
Burgoyne, Paul S.

Publication type:

Article

Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA.

Published in:

FASEB Bioadvances, 2021, v. 3, n. 4, p. 205, doi. 10.1096/fba.2020-00101

By:

Quilter, Claire R.;
Harvey, Kerry M.;
Bauer, Julien;
Skinner, Benjamin M.;
Gomez, Maria;
Shrivastava, Manu;
Doel, Andrew M.;
Drammeh, Saikou;
Dunger, David B.;
Moore, Sophie E.;
Ong, Ken K.;
Prentice, Andrew M.;
Bernstein, Robin M.;
Sargent, Carole A.;
Affara, Nabeel A.

Publication type:

Article

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 18, p. 2705, doi. 10.1093/hmg/ddi304

By:

Ellis, Peter J.I.;
Clemente, Emily J.;
Ball, Penny;
Touré, Aminata;
Ferguson, Lydia;
Turner, James M.A.;
Loveland, Kate L.;
Affara, Nabeel A.;
Burgoyne, Paul S.

Publication type:

Article

The mouse Y chromosome interval necessary for spermatogonial proliferation is gene dense with syntenic homology to the human AZFa region.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 11, p. 1713, doi. 10.1093/hmg/7.11.1713

By:

Mazeyrat, Sophie;
Saut, Noëmie;
Sargent, Carole A.;
Grimmond, Sean;
Longepied, Guy;
Ehrmann, Ingrid E.;
Ellis, Pamela S.;
Greenfield, Andy;
Affara, Nabeel A.;
Mitchell, Michael J.

Publication type:

Article

Characterization of genes encoding translation initiation factor eIF-2γ in mouse and human: sex chromosome localization, escape from X-inactivation and evolution.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 11, p. 1725, doi. 10.1093/hmg/7.11.1725

By:

Ehrmann, Ingrid E.;
Ellis, Pamela S.;
Mazeyrat, Sophie;
Duthie, Sarah;
Brockdorff, Neil;
Mattei, Marie G.;
Gavin, Marc A.;
Affara, Nabeel A.;
Brown, Graeme M.;
Simpson, Elizabeth;
Mitchell, Michael J.;
Scott, Diane M.

Publication type:

Article

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxr[sup b] interval of the mouse Y chromosome of the Dffry gene.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 1, p. 97, doi. 10.1093/hmg/7.1.97

By:

Brown, Graeme M.;
Furlong, Robert A.;
Sargent, Carole A.;
Erickson, Robert P.;
Longepied, Guy;
Mitchell, Michael;
Jones, Michael H.;
Hargreave, Timothy B.;
Cooke, Howard J.;
Affara, Nabeel A.

Publication type:

Article

Genetic Predisposition to Phaeochromocytoma: Analysis of Candidate Genes GDNF, RET and VHL.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 7, p. 1051, doi. 10.1093/hmg/6.7.1051

By:

Woodward, Emma R.;
Eng, Charis;
McMahon, Rob;
Voutilainen, Raimo;
Affara, Nabeel A.;
Ponder, Bruce A. J.;
Maher, Eamonn R.

Publication type:

Article

The Drosophila Developmental Gene Fat Facets Has a Human Homologue in Xp11.4 Which Escapes X-inactivation and Has Related Sequences on Yq11.2.

Published in:

Human Molecular Genetics, 1996, v. 5, n. 11, p. 1695, doi. 10.1093/hmg/5.11.1695

By:

Jones, Michael H.;
Furlong, Robert A.;
Burkin, Heather;
Jennifer Chalmers, I.;
Brown, Graeme M.;
Khwaja, Omar;
Affara, Nabeel A.

Publication type:

Article

Molecular analysis of de novo germline mutations in the von Hippel-Lindau disease gene.

Published in:

Human Molecular Genetics, 1995, v. 4, n. 11, p. 2139

By:

Richards, Frances M.;
Payne, Stewart J.;
Zbar, Berton;
Affara, Nabeel A.;
Ferguson-Smith, Malcolm A.;
Maher, Eamonn R.

Publication type:

Article

Somatic mutations of the von Hippel — Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma.

Published in:

Human Molecular Genetics, 1994, v. 3, n. 12, p. 2169

By:

Foster, Keith;
Prowse, Amanda;
van den Berg, Anke;
Fleming, Stewart;
Hulsbeek, Miriam M.F.;
Crossey, Paul A.;
Richards, Frances M.;
Cairns, Paul;
Affara, Nabeel A.;
Ferguson-Smith, Malcolm A.;
Buys, Charles H.CM.;
Maher, Eamonn R.

Publication type:

Article

The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.

Published in:

Human Molecular Genetics, 1994, v. 3, n. 8, p. 1317

By:

Sargent, Carole A.;
Young, Craig;
Marsh, Sharon;
Ferguson-Smith, Malcolm A.;
Affara, Nabeel A.

Publication type:

Article

Molecular genetic analysis of the 3p — syndrome.

Published in:

Human Molecular Genetics, 1994, v. 3, n. 6, p. 903

By:

Phipps, Maude E.;
Latif, Farida;
Prowse, Amanda;
Payne, Stewart J.;
Dietz-Band, Jeanne;
Leversha, Margaret;
Affara, Nabeel A.;
Moore, Anthony T.;
Tolmie, John;
Schinzel, Albert;
Lerman, Michael I.;
Ferguson-Smith, Malcolm A.;
Maher, Eamonn R.

Publication type:

Article

Detailed mapping of germline deletions of the von Hippel—Lindau disease tumour suppressor gene.

Published in:

Human Molecular Genetics, 1994, v. 3, n. 4, p. 595

By:

Richards, Frances M.;
Crossey, Paul A.;
Phlpps, Maude E.;
Foster, Keith;
Latif, Farida;
Evans, Gareth;
Sampson, Julian;
Lerman, Michael I.;
Zbar, Berton;
Affara, Nabeel A.;
Ferguson-Smith, Malcolm A.;
Maher, Eamonn R.

Publication type:

Article

Mapping the Von Hippel — Lindau disease tumour suppressor gene: identification of germline deletions by pulsed field gel electrophoresis.

Published in:

Human Molecular Genetics, 1993, v. 2, n. 7, p. 879

By:

Richards, Frances M.;
Phipps, Maude E.;
Latlf, Farida;
Yao, Masahlro;
Crossey, Paul A.;
Foster, Kelth;
Llnehan, W. Marston;
Affara, Nabeel A.;
Lerman, Michael I.;
Zbar, Berton;
Ferguson-Smith, Malcolm A.;
Maher, Eamonn R.

Publication type:

Article

Analysis of the SRY gene in 22 sex-reversed XY females identifies four new point mutations in the conserved DNA binding domain.

Published in:

Human Molecular Genetics, 1993, v. 2, n. 6, p. 785

By:

Affara, Nabeel A.;
Chalmers, I.Jennifer;
Ferguson-Smith, Malcolm A.

Publication type:

Article

Four dinucleotide repeat polymorphisms on chromosome 9 (D9S143–146).

Published in:

Human Molecular Genetics, 1992, v. 1, n. 6, p. 447

By:

Furlong, Robert A.;
Lyall, Jon E.W.;
Lush, Michael J.;
Affara, Nabeel A.;
Ferguson-Smith, Malcolm A.

Publication type:

Article

A molecular deletion map of the Y chromosome long arm defining X and autosomal homologous regions and the localisation of the HYA locus to the proximal region of the Yq euchromatin.

Published in:

Human Molecular Genetics, 1992, v. 1, n. 6, p. 379

By:

O'Reilly, Amanda J.;
Affara, Nabeel A.;
Simpson, Elizabeth;
Chandler, Phillip;
Goulmy, Els;
Ferguson-Smith, Malcolm A.

Publication type:

Article

Automated Nuclear Cartography Reveals Conserved Sperm Chromosome Territory Localization across 2 Million Years of Mouse Evolution.

Published in:

Genes, 2019, v. 10, n. 2, p. 109, doi. 10.3390/genes10020109

By:

Skinner, Benjamin Matthew;
Bacon, Joanne;
Rathje, Claudia Cattoni;
Larson, Erica Lee;
Kopania, Emily Emiko Konishi;
Good, Jeffrey Martin;
Affara, Nabeel Ahmed;
Ellis, Peter James Ivor

Publication type:

Article

Transcriptional changes in response to Xchromosome dosage in the mouse: implicationsfor X inactivation and the molecular basis of TurnerSyndrome.

Published in:

BMC Genomics, 2010, v. 11, p. 82, doi. 10.1186/1471-2164-11-82

By:

Lopes, Alexandra M.;
Burgoyne, Paul S.;
Ojarikre, Andrew;
Bauer, Julien;
Sargent, Carole A.;
Amorim, António;
Affara, Nabeel A.

Publication type:

Article

Loss of TSLC1 Causes Male Infertility Due to a Defect at the Spermatid Stage of Spermatogenesis.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 9, p. 21, doi. 10.1128/MCB.26.9.3595-3609.2006

By:

Van der Weyden, Louise;
Arends, Mark J.;
Chausiaux, Oriane E.;
Ellis, Peter J.;
Lange, Ulrike C.;
Surani, M. Azim;
Affara, Nabeel;
Murakami, Yoshinori;
Adams, David J.;
Bradley, Allan

Publication type:

Article

Two novel mouse genes mapped to chromosome Yp are expressed specifically in spermatids.

Published in:

Mammalian Genome, 2009, v. 20, n. 4, p. 193, doi. 10.1007/s00335-009-9175-8

By:

Ferguson, Lydia;
Ellis, Peter J. I.;
Affara, Nabeel A.

Publication type:

Article

Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis.

Published in:

Mammalian Genome, 2006, v. 17, n. 9, p. 956, doi. 10.1007/s00335-006-0029-3

By:

Clemente, Emily J.;
Furlong, Robert A.;
Loveland, Kate L.;
Affara, Nabeel A.

Publication type:

Article

A comparative analysis of the pig, mouse, and human PCDHX genes.

Published in:

Mammalian Genome, 2004, v. 15, n. 4, p. 296, doi. 10.1007/s00335-003-3034-9

By:

Blanco-Arias, Patricia;
Sargent, Carole A.;
Affara, Nabeel A.

Publication type:

Article

Protocadherin X (PCDHX) and Y (PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.

Published in:

Mammalian Genome, 2004, v. 15, n. 1, p. 41, doi. 10.1007/s00335-003-3028-7

By:

Blanco-Arias, Patricia;
Sargent, Carole A.;
Affara, Nabeel A.

Publication type:

Article

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

Published in:

Mammalian Genome, 2003, v. 14, n. 7, p. 437, doi. 10.1007/s00335-002-3068-4

By:

Hall, Nicola M.;
Brown, Graeme M.;
Furlong, Robert A.;
Sargent, Carole A.;
Mitchell, Michael;
Rocha, Dominique;
Affara, Nabeel A.

Publication type:

Article

A mapping and evolutionary study of porcine sex chromosome gene.

Published in:

Mammalian Genome, 2002, v. 13, n. 10, p. 588, doi. 10.1007/s00335-002-3026-1

By:

Quilter, Claire R.;
Blott, Sarah C.;
Mileham, Alan J.;
Affara, Nabeel A.;
Sargent, Carole A.;
Griffin, Darren K.

Publication type:

Article

The human-specific Yp11.2/Xq21.3 homology block encodes a potentially functional testis-specific TGIF-like retroposon.

Published in:

Mammalian Genome, 2002, v. 13, n. 8, p. 463, doi. 10.1007/s00335-002-3010-9

By:

Blanco-Arias, Patricia;
Sargent, Carole A.;
Affara, Nabeel A.

Publication type:

Article