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Histopathological and molecular features of late relapses in non-seminomas.
Published in:
BJU International, 2011, v. 107, n. 6, p. 936, doi. 10.1111/j.1464-410X.2010.09631.x
By:
- Mayer, Frank;
- Wermann, Hendrik;
- Albers, Peter;
- Stoop, Hans;
- Gillis, Ad J. M.;
- Hartmann, Jörg T.;
- Bokemeyer, C. Carsten;
- Oosterhuis, J. Wolter;
- Looijenga, Leendert H. J.;
- Honecker, Friedemann
Publication type:
Article
The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11774, doi. 10.3390/ijms222111774
By:
- Timmerman, Dennis M.;
- Eleveld, Thomas F.;
- Gillis, Ad J. M.;
- Friedrichs, Carlijn C.;
- Hillenius, Sanne;
- Remmers, Tessa L.;
- Sriram, Sruthi;
- Looijenga, Leendert H. J.
Publication type:
Article
Recurrence of a Mediastinal Germ-Cell Tumor as a Somatic-Type Malignancy: A Complex Case Report.
Published in:
2021
By:
- Hulsker, Caroline C. C.;
- Kranendonk, Mariëtte E. G.;
- Eleveld, Thomas F.;
- Gillis, Ad J. M.;
- van de Ven, Cornelis P.;
- van Eijkelenburg, Natasha K. A.;
- van der Kaaij, Niels P.;
- van der Steeg, Alida F. W.;
- Looijenga, Leendert H. J.
Publication type:
Case Study
Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 2, p. 258, doi. 10.3390/ijms20020258
By:
- Lobo, João;
- Gillis, Ad J. M.;
- Jerónimo, Carmen;
- Henrique, Rui;
- Looijenga, Leendert H. J.
Publication type:
Article
Role of gain of 12p in germ cell tumour development.
Published in:
APMIS, 2003, v. 111, n. 1, p. 161, doi. 10.1034/j.1600-0463.2003.11101201.x
By:
- LOOIJENGA, LEENDERT H. J;
- ZAFARANA, GAETANO;
- GRYGALEWICZ, BEATA;
- SUMMERSGILL, BRENDA;
- DEBIEC-RYCHTER, MARIA;
- VELTMAN, JORIS;
- SCHOENMAKERS, ERIC F. P. M;
- RODRIGUEZ, SANDRINE;
- JAFER, OSMAN;
- CLARK, JEREMY;
- VAN KESSEL, AD GEURTS;
- SHIPLEY, JANET;
- VAN GURP, RUUD J. H. L. M;
- GILLIS, AD J. M;
- OOSTERHUIS, J. WOLTER
Publication type:
Article
Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers.
Published in:
2020
By:
- Lobo, João;
- Gillis, Ad J. M.;
- van den Berg, Annette;
- Looijenga, Leendert H. J.
Publication type:
journal article
Chromosomes and Expression in Human Testicular Germ-Cell Tumors.
Published in:
Annals of the New York Academy of Sciences, 2007, v. 1120, p. 187, doi. 10.1196/annals.1411.000
By:
- LOOIJENGA, LEENDERT H. J.;
- GILLIS, AD. J. M.;
- STOOP, HANS J.;
- HERSMUS, REMKO;
- OOSTERHUIS, J. WOLTER
Publication type:
Article
Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence.
Published in:
Nature Communications, 2023, p. 1, doi. 10.1038/s41467-023-38378-9
By:
- Xu, Lin;
- Pierce, Joshua L.;
- Sanchez, Angelica;
- Chen, Kenneth S.;
- Shukla, Abhay A.;
- Fustino, Nicholas J.;
- Stuart, Sarai H.;
- Bagrodia, Aditya;
- Xiao, Xue;
- Guo, Lei;
- Krailo, Mark D.;
- Shaikh, Furqan;
- Billmire, Deborah F.;
- Pashankar, Farzana;
- Bestrashniy, Jessica;
- Oosterhuis, J. Wolter;
- Gillis, Ad J. M.;
- Xie, Yang;
- Teot, Lisa;
- Mora, Jaume
Publication type:
Article
Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0122146
By:
- Rijlaarsdam, Martin A.;
- Tax, David M. J.;
- Gillis, Ad J. M.;
- Dorssers, Lambert C. J.;
- Koestler, Devin C.;
- de Ridder, Jeroen;
- Looijenga, Leendert H. J.
Publication type:
Article
Seminoma and Embryonal Carcinoma Footprints Identified by Analysis of Integrated Genome-Wide Epigenetic and Expression Profiles of Germ Cell Cancer Cell Lines.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098330
By:
- van der Zwan, Yvonne G.;
- Rijlaarsdam, Martin A.;
- Rossello, Fernando J.;
- Notini, Amanda J.;
- de Boer, Suzan;
- Watkins, D. Neil;
- Gillis, Ad J. M.;
- Dorssers, Lambert C. J.;
- White, Stefan J.;
- Looijenga, Leendert H. J.
Publication type:
Article
Role of SOX2 in the Etiology of Embryonal Carcinoma, Based on Analysis of the NCCIT and NT2 Cell Lines.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0083585
By:
- Eini, Ronak;
- Stoop, Hans;
- Gillis, Ad J. M.;
- Biermann, Katharina;
- Dorssers, Lambert C. J.;
- Looijenga, Leendert H. J.
Publication type:
Article
12p-Amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH.
Published in:
Oncogene, 2003, v. 22, n. 48, p. 7695, doi. 10.1038/sj.onc.1207011
By:
- Zafarana, Gaetano;
- Grygalewicz, Beata;
- Gillis, Ad J M;
- Vissers, Lisenka E L M;
- van de Vliet, Walter;
- van Gurp, Ruud J H L M;
- Stoop, Hans;
- Debiec-Rychter, Maria;
- Oosterhuis, Jan Wolter;
- van Kessel, Ad Geurts;
- Schoenmakers, Eric F P M;
- Looijenga, Leendert H J;
- Veltman, Joris A
Publication type:
Article
Combining Hypermethylated RASSF1A Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients.
Published in:
Cancers, 2021, v. 13, n. 20, p. 5228, doi. 10.3390/cancers13205228
By:
- Lobo, João;
- van Zogchel, Lieke M. J.;
- Nuru, Mohammed G.;
- Gillis, Ad J. M.;
- van der Schoot, C. Ellen;
- Tytgat, Godelieve A. M.;
- Looijenga, Leendert H. J.
Publication type:
Article
Comparative Analyses of Liquid-Biopsy MicroRNA371a-3p Isolation Protocols for Serum and Plasma.
Published in:
Cancers, 2021, v. 13, n. 17, p. 4260, doi. 10.3390/cancers13174260
By:
- Timmerman, Dennis M.;
- Gillis, Ad J. M.;
- Mego, Michal;
- Looijenga, Leendert H. J.
Publication type:
Article
CRIPTO and miR-371a-3p Are Serum Biomarkers of Testicular Germ Cell Tumors and Are Detected in Seminal Plasma from Azoospermic Males.
Published in:
Cancers, 2020, v. 12, n. 3, p. 760, doi. 10.3390/cancers12030760
By:
- Spiller, Cassy M.;
- Lobo, João;
- Boellaard, Willem P. A.;
- Gillis, Ad J. M.;
- Bowles, Josephine;
- Looijenga, Leendert H. J.
Publication type:
Article
XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality.
Published in:
Cancers, 2019, v. 11, n. 9, p. 1385, doi. 10.3390/cancers11091385
By:
- Lobo, João;
- Nunes, Sandra P.;
- Gillis, Ad J. M.;
- Barros-Silva, Daniela;
- Miranda-Gonçalves, Vera;
- Berg, Annette van den;
- Cantante, Mariana;
- Guimarães, Rita;
- Henrique, Rui;
- Jerónimo, Carmen;
- Looijenga, Leendert H. J.
Publication type:
Article
Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness.
Published in:
Cancer Cell International, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12935-020-01458-7
By:
- Schmidtova, Silvia;
- Dorssers, Lambert C. J.;
- Kalavska, Katarina;
- Gillis, Ad J. M.;
- Oosterhuis, J. Wolter;
- Stoop, Hans;
- Miklikova, Svetlana;
- Kozovska, Zuzana;
- Burikova, Monika;
- Gercakova, Katarina;
- Durinikova, Erika;
- Chovanec, Michal;
- Mego, Michal;
- Kucerova, Lucia;
- Looijenga, Leendert H. J.
Publication type:
Article
Diagnosis of testicular carcinoma in situ'(intratubular and microinvasive)' seminoma and embryonal carcinoma using direct enzymatic alkaline phosphatase reactivity on frozen histological sections.
Published in:
Histopathology, 2011, v. 58, n. 3, p. 440, doi. 10.1111/j.1365-2559.2011.03767.x
By:
- Stoop, Hans;
- Kirkels, Wim;
- Dohle, Gert R.;
- Gillis, Ad J. M.;
- den Bakker, Michael A;
- Biermann, Katharina;
- Oosterhuis, Wolter;
- Looijenga, Leendert H. J.
Publication type:
Article
Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development.
Published in:
2019
By:
- Dorssers, Lambert C. J.;
- Gillis, Ad J. M.;
- Stoop, Hans;
- van Marion, Ronald;
- Nieboer, Marleen M.;
- van Riet, Job;
- van de Werken, Harmen J. G.;
- Oosterhuis, J. Wolter;
- de Ridder, Jeroen;
- Looijenga, Leendert H. J.
Publication type:
journal article
A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours.
Published in:
2016
By:
- Murray, Matthew J;
- Bell, Emma;
- Raby, Katie L;
- Rijlaarsdam, Martin A;
- Gillis, Ad J M;
- Looijenga, Leendert H J;
- Brown, Helen;
- Destenaves, Benoit;
- Nicholson, James C;
- Coleman, Nicholas
Publication type:
journal article
Further characterization of the first seminoma cell line TCam-2.
Published in:
Genes, Chromosomes & Cancer, 2008, v. 47, n. 3, p. 185, doi. 10.1002/gcc.20520
By:
- de Jong, Jeroen;
- Stoop, Hans;
- Gillis, Ad J. M.;
- Hersmus, Remko;
- van Gurp, Ruud J. H. L. M.;
- van de Geijn, Gert-Jan M.;
- van Drunen, Ellen;
- Beverloo, H. Berna;
- Schneider, Dominik T.;
- Sherlock, Jon K.;
- Baeten, John;
- Kitazawa, Sohei;
- van Zoelen, E. Joop;
- van Roozendaal, Kees;
- Oosterhuis, J. Wolter;
- Looijenga, Leendert H. J.
Publication type:
Article
IGF2/H19 imprinting analysis of human germ cell tumors (GCTs) using the methylation‐sensitive single‐nucleotide primer extension method reflects the origin of GCTs in different stages of primordial germ cell development.
Published in:
Genes, Chromosomes & Cancer, 2005, v. 44, n. 3, p. 256, doi. 10.1002/gcc.20237
By:
- Sonja Sievers;
- Katayoun Alemazkour;
- Susanne Zahn;
- Elizabeth J. Perlman;
- Ad J. M. Gillis;
- Leendert H. J. Looijenga;
- Ulrich Göbel;
- Dominik T. Schneider
Publication type:
Article
Origin and biology of a testicular wilms' tumor.
Published in:
Genes, Chromosomes & Cancer, 1994, v. 11, n. 2, p. 126, doi. 10.1002/gcc.2870110209
By:
- Gillis, Ad J. M.;
- Oosterhuis, J. Wolter;
- Schipper, Magriet E. I.;
- Barten, E. J.;
- Van Berlo, Romy;
- Van Gurp, Ruud J. H. L. M.;
- Abraham, Mary;
- Saunders, Grady F.;
- Looijenga, Leendert H. J.
Publication type:
Article
Testicular germ cell tumors of adults show deletions of chromosomal bands 11 p13 and 11p15.5, but no abnormalities within the zinc-finger regions and exons 2 and 6 of the wilms' Tumor 1 Gene.
Published in:
Genes, Chromosomes & Cancer, 1994, v. 9, n. 3, p. 153, doi. 10.1002/gcc.2870090302
By:
- Looijenga, Leendert H. J.;
- Gillis, Ad J. M.;
- Oosterhuis, J. Wolter;
- Abraham, Mary;
- Sunders, Grady F.
Publication type:
Article
Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas.
Published in:
PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003384
By:
- Basten, Sander G.;
- Davis., Erica E.;
- Gillis., Ad J. M.;
- van Rooijen, Ellen;
- Stoop, Hans;
- Babala, Nikolina;
- Logister, Ive;
- Heath, Zachary G.;
- Jonges, Trudy N.;
- Katsanis, Nicholas;
- Voest, Emile E.;
- van Eeden, Freek J.;
- Medema, Rene H.;
- Ketting, René F.;
- Schulte-Merker, Stefan;
- Looijenga, Leendert H. J.;
- Giles, Rachel H.
Publication type:
Article
miMsg: a target enrichment algorithm for predicted miR–mRNA interactions based on relative ranking of matched expression data.
Published in:
Bioinformatics, 2013, v. 29, n. 13, p. 1638, doi. 10.1093/bioinformatics/btt246
By:
- Rijlaarsdam, Martin A.;
- Rijlaarsdam, David J.;
- Gillis, Ad J. M.;
- Dorssers, Lambert C. J.;
- Looijenga, Leendert H. J.
Publication type:
Article
The platelet-derived growth factor α-receptor 1.5 kb transcript: Target for molecular detection of testicular germ cell tumours of adolescents and adults.
Published in:
APMIS, 1998, v. 106, n. 1-6, p. 207, doi. 10.1111/j.1699-0463.1998.tb01337.x
By:
- OOSTERHUIS, J. WOLTER;
- GILLIS, AD J. M.;
- ROOZENDAAL, CORNELIUS E. P.;
- ZOELEN, EVERARDUS J. J.;
- LOOIJENGA, LEENDERT H. J.
Publication type:
Article
Genomic imprinting in testicular germ cell tumours.
Published in:
APMIS, 1998, v. 106, n. 1-6, p. 187, doi. 10.1111/j.1699-0463.1998.tb01335.x
By:
- LOOIJENGA, LEENDERT H. J.;
- VERKERK, ANNEMIEKE J. M. H.;
- DEKKER, MARJOLEIN C.;
- GURP, RUUD J. H. L. M.;
- GILLIS, AD J. M.;
- OOSTERHUIS, J. WOLTER
Publication type:
Article
Serum microRNA profiles in athyroid patients on and off levothyroxine therapy.
Published in:
PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0194259
By:
- Massolt, Elske T.;
- Chaker, Layal;
- Visser, Theo J.;
- Gillis, Ad J. M.;
- Dorssers, Lambert C. J.;
- Beukhof, Carolien M.;
- Kam, Boen L. R.;
- Franssen, Gaston J.;
- Brigante, Giulia;
- van Ginhoven, Tessa M.;
- Visser, W. Edward;
- Looijenga, Leendert H. J.;
- Peeters, Robin P.
Publication type:
Article
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline.
Published in:
PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0178169
By:
- Giannoulatou, Eleni;
- Maher, Geoffrey J.;
- Ding, Zhihao;
- Gillis, Ad J. M.;
- Dorssers, Lambert C. J.;
- Hoischen, Alexander;
- Rajpert-De Meyts, Ewa;
- null, null;
- McVean, Gilean;
- Wilkie, Andrew O. M.;
- Looijenga, Leendert H. J.;
- Goriely, Anne
Publication type:
Article

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