Works by Accili, Domenico

Results: 116

Application of combined omics platforms to accelerate biomedical discovery in diabesity.

Published in:

Annals of the New York Academy of Sciences, 2013, v. 1287, n. 1, p. 1, doi. 10.1111/nyas.12116

By:

Kurland, Irwin J.;
Accili, Domenico;
Burant, Charles;
Fischer, Steven M.;
Kahn, Barbara B.;
Newgard, Christopher B.;
Ramagiri, Suma;
Ronnett, Gabriele V.;
Ryals, John A.;
Sanders, Mark;
Shambaugh, Joe;
Shockcor, John;
Gross, Steven S.

Publication type:

Article

Reprogramming Cells to Make Insulin.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 6, p. 1214, doi. 10.1210/js.2019-00040

By:

McKimpson, Wendy M;
Accili, Domenico

Publication type:

Article

Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation.

Published in:

PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0297555

By:

Watanabe, Hitoshi;
Asahara, Shun-ichiro;
Son, Jinsook;
McKimpson, Wendy M.;
de Cabo, Rafael;
Accili, Domenico

Publication type:

Article

Mechanisms of β cell failure in the pathogenesis of Type 2 diabetes.

Published in:

Drug Development Research, 2008, v. 69, n. 3, p. 111, doi. 10.1002/ddr.20234

By:

Accili, Domenico

Publication type:

Article

Regulation of insulin-like growth facto-dependent myoblast differentiation by Foxo forkhead transcription factors.

Published in:

Journal of Cell Biology, 2003, v. 162, n. 4, p. 535, doi. 10.1083/jcb.200212107

By:

Hribal, Marta L.;
Nakae, Jun;
Kitamura, Tadahiro;
Shutter, John R.;
Accili, Domenico

Publication type:

Article

Transgenic Mice to Study the Role of Dopamine Receptors in Cardiovascular Function.

Published in:

Clinical & Experimental Hypertension, 1997, v. 19, n. 1/2, p. 15, doi. 10.3109/10641969709080801

By:

Jose, Pedro A.;
Drago, John;
Accili, Domenico;
Eisner, Gilbert M.;
Felder, Robin A.

Publication type:

Article

Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 3, p. 441, doi. 10.1002/emmm.201201475

By:

Fiorentino, Loredana;
Cavalera, Michele;
Menini, Stefano;
Marchetti, Valentina;
Mavilio, Maria;
Fabrizi, Marta;
Conserva, Francesca;
Casagrande, Viviana;
Menghini, Rossella;
Pontrelli, Paola;
Arisi, Ivan;
D'Onofrio, Mara;
Lauro, Davide;
Khokha, Rama;
Accili, Domenico;
Pugliese, Giuseppe;
Gesualdo, Loreto;
Lauro, Renato;
Federici, Massimo

Publication type:

Article

Corrigendum: Structure-based prediction of protein-protein interactions on a genome-wide scale.

Published in:

Nature, 2013, v. 495, n. 7439, p. 127, doi. 10.1038/nature11977

By:

Zhang, Qiangfeng Cliff;
Petrey, Donald;
Deng, Lei;
Qiang, Li;
Shi, Yu;
Thu, Chan Aye;
Bisikirska, Brygida;
Lefebvre, Celine;
Accili, Domenico;
Hunter, Tony;
Maniatis, Tom;
Califano, Andrea;
Honig, Barry

Publication type:

Article

Structure-based prediction of protein-protein interactions on a genome-wide scale.

Published in:

Nature, 2012, v. 490, n. 7421, p. 556, doi. 10.1038/nature11503

By:

Zhang, Qiangfeng Cliff;
Petrey, Donald;
Deng, Lei;
Qiang, Li;
Shi, Yu;
Thu, Chan Aye;
Bisikirska, Brygida;
Lefebvre, Celine;
Accili, Domenico;
Hunter, Tony;
Maniatis, Tom;
Califano, Andrea;
Honig, Barry

Publication type:

Article

A note of caution on the Knockout Mouse Project.

Published in:

2004

By:

Accili, Domenico

Publication type:

Letter

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

Published in:

Nature Genetics, 2002, v. 32, n. 2, p. 245, doi. 10.1038/ng890

By:

Nakae, Jun;
Biggs, William H.;
Kitamura, Tadahiro;
Cavenee, Webster K.;
Wright, Christopher V.E.;
Arden, Karen C.;
Accili, Domenico

Publication type:

Article

Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.

Published in:

Nature Genetics, 1998, v. 20, n. 3, p. 294, doi. 10.1038/3112

By:

Lauro, Davide;
Kido, Yoshiaki;
Castle, Arthur L.;
Zarnowski, Mary-Jane;
Hayashi, Hideki;
Ebina, Yousuke;
Accili, Domenico

Publication type:

Article

The new biology of diabetes.

Published in:

Diabetologia, 2015, v. 58, n. 11, p. 2459, doi. 10.1007/s00125-015-3722-5

By:

Pajvani, Utpal;
Accili, Domenico

Publication type:

Article

Erratum to: The new biology of diabetes.

Published in:

2015

By:

Pajvani, Utpal;
Accili, Domenico

Publication type:

Erratum

Dopamine Receptors and Dopamine Transporter in Brain Function and Addictive Behaviors: Insights from Targeted Mouse Mutants.

Published in:

Developmental Neuroscience, 1998, v. 20, n. 2/3, p. 188, doi. 10.1159/000017313

By:

Drago, John;
Padungchaichot, Poolpol;
Accili, Domenico;
Fuchs, Sara

Publication type:

Article

Targeted Gene Mutations Define the Roles of Insulin and IGF-I Receptors in Mouse Embryonic Development.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 1999, v. 12, n. 4, p. 475, doi. 10.1515/jpem.1999.12.4.475

By:

Accili, Domenico;
Nakae, Jun;
Kim, Jane J.;
Park, Byung-Chul;
Rother, Kristina I.

Publication type:

Article

Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.

Published in:

Nature Medicine, 2013, v. 19, n. 8, p. 1054, doi. 10.1038/nm.3259

By:

Pajvani, Utpal B;
Qiang, Li;
Kangsamaksin, Thaned;
Kitajewski, Jan;
Ginsberg, Henry N;
Accili, Domenico

Publication type:

Article

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.

Published in:

Nature Medicine, 2011, v. 17, n. 8, p. 961, doi. 10.1038/nm.2378

By:

Pajvani, Utpal B.;
Shawber, Carrie J.;
Samuel, Varman T.;
Birkenfeld, Andreas L.;
Shulman, Gerald I.;
Kitajewski, Jan;
Accili, Domenico

Publication type:

Article

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake.

Published in:

Nature Medicine, 2009, v. 15, n. 10, p. 1195, doi. 10.1038/nm.2026

By:

Plum, Leona;
Lin, Hua V.;
Dutia, Roxanne;
Tanaka, Jun;
Aizawa, Kumiko S.;
Matsumoto, Michihiro;
Kim, Andrea J.;
Cawley, Niamh X.;
Paik, Ji-Hye;
Y. Peng Loh;
DePinho, Ronald A.;
Wardlaw, Sharon L.;
Accili, Domenico

Publication type:

Article

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake.

Published in:

Nature Medicine, 2006, v. 12, n. 5, p. 534, doi. 10.1038/nm1392

By:

Kitamura, Tadahiro;
Yun Feng;
Ido Kitamura, Yukari;
Chua, Streamson C.;
Xu, Allison W.;
Barsh, Gregory S.;
Rossetti, Luciano;
Accili, Domenico

Publication type:

Article

The tangled path to glucose production.

Published in:

Nature Medicine, 2006, v. 12, n. 1, p. 33, doi. 10.1038/nm0106-33

By:

Matsumoto, Michihiro;
Accili, Domenico

Publication type:

Article

Turning up the heat in the fat cell.

Published in:

Nature Medicine, 2004, v. 10, n. 11, p. 1168, doi. 10.1038/nm1104-1168

By:

Accili, Domenico;
Valenti, Luca

Publication type:

Article

Mutations in insulin-receptor gene in insulin-resistant patients.

Published in:

1990

By:

Taylor, Simeon I.;
Kadowaki, Takahi;
Kadowaki, Hiroko;
Accili, Domenico;
Cama, Alessandro;
McKeon, Catherine;
Taylor, S I;
Kadowaki, T;
Kadowaki, H;
Accili, D;
Cama, A;
McKeon, C

Publication type:

journal article

MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis.

Published in:

Diabetes, 2023, v. 72, n. 12, p. 1781, doi. 10.2337/db23-0314

By:

Park, Junhee;
Hall, Catherine;
Hubbard, Brandon;
LaMoia, Traci;
Gaspar, Rafael;
Nasiri, Ali;
Li, Fang;
Zhang, Hanrui;
Kim, Jiyeon;
Haeusler, Rebecca A.;
Accili, Domenico;
Shulman, Gerald I.;
Yu, Hongtao;
Choi, Eunhee

Publication type:

Article

Susumu Seino, MD, DMSci (1948–2021): A Pioneer in the Biology of Insulin Secretion.

Published in:

2022

By:

Accili, Domenico;
Bell, Graeme I.;
Thorens, Bernard

Publication type:

Obituary

PPARγ Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment.

Published in:

2020

By:

Liu, Longhua;
Fan, Lihong;
Chan, Michelle;
Kraakman, Michael J.;
Yang, Jing;
Fan, Yong;
Aaron, Nicole;
Wan, Qianfen;
Carrillo-Sepulveda, Maria Alicia;
Tall, Alan R.;
Tabas, Ira;
Accili, Domenico;
Qiang, Li

Publication type:

journal article

2071-P: C2CD4A, Pancreatic Beta-Cell Function, and Type 2 Diabetes Susceptibility.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2071-P

By:

KUO, TAIYI;
ACCILI, DOMENICO

Publication type:

Article

Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes.

Published in:

Diabetes, 2019, v. 68, n. 6, p. 1156, doi. 10.2337/db18-1236

By:

Liheng Wang;
Qiongming Liu;
Takumi Kitamoto;
Junjie Hou;
Jun Qin;
Accili, Domenico

Publication type:

Article

Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes.

Published in:

2019

By:

Wang, Liheng;
Liu, Qiongming;
Kitamoto, Takumi;
Hou, Junjie;
Qin, Jun;
Accili, Domenico

Publication type:

journal article

Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture.

Published in:

2018

By:

Accili, Domenico

Publication type:

journal article

Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in Mice.

Published in:

2017

By:

Emi Ishida;
Kim-Muller, Ja Young;
Accili, Domenico;
Ishida, Emi

Publication type:

journal article

Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.

Published in:

2016

By:

Vazirani, Reema P.;
Verma, Akanksha;
Sadacca, L. Amanda;
Buckman, Melanie S.;
Picatoste, Belen;
Beg, Muheeb;
Torsitano, Christopher;
Bruno, Joanne H.;
Patel, Rajesh T.;
Simonyte, Kotryna;
Camporez, Joao P.;
Moreira, Gabriela;
Falcone, Domenick J.;
Accili, Domenico;
Elemento, Olivier;
Shulman, Gerald I.;
Kahn, Barbara B.;
McGraw, Timothy E.

Publication type:

journal article

Homozygosity for a null allele of the insulin receptor gene in a patient with leprechaunism.

Published in:

Human Mutation, 1995, v. 6, n. 1, p. 17, doi. 10.1002/humu.1380060105

By:

Hone, Jennifer;
Accili, Domenico;
Psiachou, Helen;
Alghband-Zadeh, Jamie;
Mitton, Sally;
Wertheimer, Efrat;
Sinclair, Leonard;
Taylor, Simeon I.

Publication type:

Article

Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes.

Published in:

Science Translational Medicine, 2023, v. 15, n. 681, p. 1, doi. 10.1126/scitranslmed.abq4126

By:

Watanabe, Hitoshi;
Du, Wen;
Son, Jinsook;
Sui, Lina;
Asahara, Shun-ichiro;
Kurland, Irwin J.;
Kuo, Taiyi;
Kitamoto, Takumi;
Miyachi, Yasutaka;
de Cabo, Rafael;
Accili, Domenico

Publication type:

Article

Vitamin D and COVID-19.

Published in:

European Journal of Endocrinology, 2020, v. 183, n. 5, p. 133, doi. 10.1530/EJE-20-0665

By:

Bilezikian, John P.;
Bikle, Daniel;
Hewison, Martin;
Lazaretti-Castro, Marise;
Formenti, Anna Maria;
Gupta, Aakriti;
Madhavan, Mahesh V.;
Nair, Nandini;
Babalyan, Varta;
Hutchings, Nicholas;
Napoli, Nicola;
Accili, Domenico;
Binkley, Neil;
Landry, Donald W.;
Giustina, Andrea

Publication type:

Article

Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study.

Published in:

Respiratory Research, 2012, v. 13, n. 9, p. 1, doi. 10.1186/1465-9921-13-79

By:

Wallace, Alison M.;
Mercer, Becky A.;
He, Jianqing;
Foronjy, Robert F.;
Accili, Domenico;
Sandford, Andrew J.;
Paré, Peter D.;
D'Armiento, Jeanine M.`

Publication type:

Article

Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study.

Published in:

2012

By:

Wallace, Alison M;
Mercer, Becky A;
He, Jianqing;
Foronjy, Robert F;
Accili, Domenico;
Sandford, Andrew J;
Paré, Peter D;
D'Armiento, Jeanine M

Publication type:

journal article

Reversing pancreatic β-cell dedifferentiation in the treatment of type 2 diabetes.

Published in:

Experimental & Molecular Medicine EMM, 2023, v. 55, n. 8, p. 1652, doi. 10.1038/s12276-023-01043-8

By:

Son, Jinsook;
Accili, Domenico

Publication type:

Article

Mutations in the Insulin Receptor Gene in Patients with Genetic Syndromes of Insulin Resistance and Acanthosis Nigricans.

Published in:

Journal of Investigative Dermatology, 1992, v. 98, n. 6, p. 77S, doi. 10.1111/1523-1747.ep12462281

By:

Accili, Domenico;
Barbetti, Fabrizio;
Cama, Alessandro;
Kadowaki, Hiroko;
Kadowaki, Takashi;
Imano, Eiichi;
Levy-Toledano, Rachel;
Taylor, Simeon I.

Publication type:

Article

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR.

Published in:

EMBO Journal, 2000, v. 19, n. 5, p. 989, doi. 10.1093/emboj/19.5.989

By:

Nakae, Jun;
Barr, Valarie;
Accili, Domenico

Publication type:

Article

Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.

Published in:

Journal of Cell Biology, 2024, v. 223, n. 10, p. 1, doi. 10.1083/jcb.202305093

By:

McKimpson, Wendy M.;
Spiegel, Sophia;
Mukhanova, Maria;
Kraakman, Michael;
Wen Du;
Takumi Kitamoto;
Junjie Yu;
Zhaobin Deng;
Pajvani, Utpal;
Accili, Domenico

Publication type:

Article

Hypoglycemia Secondary to Sulfonylurea Ingestion in a Patient with End Stage Renal Disease: Results from a 72-Hour Fast.

Published in:

Case Reports in Endocrinology, 2015, p. 1, doi. 10.1155/2015/742781

By:

Abraham, Alice;
Rubin, Mishaela;
Accili, Domenico;
Bilezikian, John P.;
Pajvani, Utpal B.

Publication type:

Article

Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.

Published in:

Nature Communications, 2016, v. 7, n. 8, p. 12631, doi. 10.1038/ncomms12631

By:

Kim-Muller, Ja Young;
Fan, Jason;
Kim, Young Jung R.;
Lee, Seung-Ah;
Ishida, Emi;
Blaner, William S.;
Accili, Domenico

Publication type:

Article

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

Published in:

Nature Communications, 2014, v. 5, n. 10, p. 5190, doi. 10.1038/ncomms6190

By:

Haeusler, Rebecca A.;
Hartil, Kirsten;
Vaitheesvaran, Bhavapriya;
Arrieta-Cruz, Isabel;
Knight, Colette M.;
Cook, Joshua R.;
Kammoun, Helene L.;
Febbraio, Mark A.;
Gutierrez-Juarez, Roger;
Kurland, Irwin J.;
Accili, Domenico

Publication type:

Article

FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures.

Published in:

Nature Communications, 2014, v. 5, n. 6, p. 4242, doi. 10.1038/ncomms5242

By:

Bouchi, Ryotaro;
Foo, Kylie S.;
Hua, Haiqing;
Tsuchiya, Kyoichiro;
Ohmura, Yoshiaki;
Sandoval, P. Rodrigo;
Ratner, Lloyd E.;
Egli, Dieter;
Leibel, Rudolph L.;
Accili, Domenico

Publication type:

Article

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

Published in:

PLoS ONE, 2021, v. 16, n. 11, p. 1, doi. 10.1371/journal.pone.0260526

By:

Miyachi, Yasutaka;
Kuo, Taiyi;
Son, Jinsook;
Accili, Domenico

Publication type:

Article

Altered Central Nutrient Sensing in Male Mice Lacking Insulin Receptors in Glut4-Expressing Neurons.

Published in:

Endocrinology, 2019, v. 160, n. 9, p. 2038, doi. 10.1210/en.2019-00341

By:

Ren, Hongxia;
Vieira-de-Abreu, Adriana;
Yan, Shijun;
Reilly, Austin M;
Chan, Owen;
Accili, Domenico

Publication type:

Article

Effect of activating and inactivating mutations of G.

Published in:

Journal of Cellular Biochemistry, 1997, v. 64, n. 2, p. 242, doi. 10.1002/(SICI)1097-4644(199702)64:2<242::AID-JCB8>3.0.CO;2-X

By:

Gordeladze, Jan Oxholm;
Høvik, Kjerstin Elisabeth;
Merendino, John Jack;
Hermouet, Sylvie;
Gutkind, Silvio;
Accili, Domenico

Publication type:

Article

New Insights into the Integrated Physiology of Insulin Action.

Published in:

Reviews in Endocrine & Metabolic Disorders, 2004, v. 5, n. 2, p. 143

By:

Yukari Kitamura;
Domenico Accili

Publication type:

Article

Testis determination requires insulin receptor family function in mice.

Published in:

Nature, 2003, v. 426, n. 6964, p. 291, doi. 10.1038/nature02059

By:

Nef, Serge;
Verma-Kurvari, Sunita;
Merenmies, Jussi;
Vassalli, Jean-Dominique;
Efstratiadis, Argiris;
Accili, Domenico;
Parada, Luis F.

Publication type:

Article