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Application of combined omics platforms to accelerate biomedical discovery in diabesity.
- Published in:
- Annals of the New York Academy of Sciences, 2013, v. 1287, n. 1, p. 1, doi. 10.1111/nyas.12116
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- Publication type:
- Article
Reprogramming Cells to Make Insulin.
- Published in:
- Journal of the Endocrine Society, 2019, v. 3, n. 6, p. 1214, doi. 10.1210/js.2019-00040
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- Publication type:
- Article
Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes.
- Published in:
- Science Translational Medicine, 2023, v. 15, n. 681, p. 1, doi. 10.1126/scitranslmed.abq4126
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- Publication type:
- Article
Dopamine Receptors and Dopamine Transporter in Brain Function and Addictive Behaviors: Insights from Targeted Mouse Mutants.
- Published in:
- Developmental Neuroscience, 1998, v. 20, n. 2/3, p. 188, doi. 10.1159/000017313
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- Publication type:
- Article
Reversing pancreatic β-cell dedifferentiation in the treatment of type 2 diabetes.
- Published in:
- Experimental & Molecular Medicine EMM, 2023, v. 55, n. 8, p. 1652, doi. 10.1038/s12276-023-01043-8
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- Publication type:
- Article
Regulation of insulin-like growth facto-dependent myoblast differentiation by Foxo forkhead transcription factors.
- Published in:
- Journal of Cell Biology, 2003, v. 162, n. 4, p. 535, doi. 10.1083/jcb.200212107
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- Publication type:
- Article
Targeted Gene Mutations Define the Roles of Insulin and IGF-I Receptors in Mouse Embryonic Development.
- Published in:
- Journal of Pediatric Endocrinology & Metabolism, 1999, v. 12, n. 4, p. 475, doi. 10.1515/jpem.1999.12.4.475
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- Publication type:
- Article
Altered Central Nutrient Sensing in Male Mice Lacking Insulin Receptors in Glut4-Expressing Neurons.
- Published in:
- Endocrinology, 2019, v. 160, n. 9, p. 2038, doi. 10.1210/en.2019-00341
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- Publication type:
- Article
Effect of activating and inactivating mutations of G.
- Published in:
- Journal of Cellular Biochemistry, 1997, v. 64, n. 2, p. 242, doi. 10.1002/(SICI)1097-4644(199702)64:2<242::AID-JCB8>3.0.CO;2-X
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- Publication type:
- Article
Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36315-4
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- Publication type:
- Article
Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33008-2
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- Publication type:
- Article
Activation of the insulin receptor by an insulin mimetic peptide.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33274-0
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- Publication type:
- Article
Diabetes treatment by conversion of gut epithelial cells to insulin‐producing cells.
- Published in:
- Journal of Diabetes Investigation, 2024, v. 15, n. 7, p. 797, doi. 10.1111/jdi.14175
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- Publication type:
- Article
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay.
- Published in:
- EMBO Molecular Medicine, 2013, v. 5, n. 3, p. 441, doi. 10.1002/emmm.201201475
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- Publication type:
- Article
Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.
- Published in:
- PLoS ONE, 2021, v. 16, n. 11, p. 1, doi. 10.1371/journal.pone.0260526
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- Publication type:
- Article
Unraveling the mysteries of hepatic insulin signaling: deconvoluting the nuclear targets of insulin.
- Published in:
- Endocrine Journal, 2023, v. 70, n. 9, p. 851, doi. 10.1507/endocrj.EJ23-0150
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- Publication type:
- Article
Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR.
- Published in:
- EMBO Journal, 2000, v. 19, n. 5, p. 989, doi. 10.1093/emboj/19.5.989
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- Publication type:
- Article
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.
- Published in:
- 2016
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- Publication type:
- journal article
Proinsulin in Girls: Relationship to Obesity, Hyperinsulinemia, and Puberty.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 10, p. 4673, doi. 10.1210/jc.2001-011535
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- Publication type:
- Article
CLINICAL REVIEW 125: The Insulin Receptor and Its Cellular Targets.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 3, p. 972, doi. 10.1210/jcem.86.3.7306
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- Publication type:
- Article
Alain Ktorza, PhD.
- Published in:
- 2017
- By:
- Publication type:
- Other
The hyperstimulated β-cell: prelude to diabetes?
- Published in:
- Diabetes, Obesity & Metabolism, 2012, v. 14, p. iv, doi. 10.1111/j.1463-1326.2012.01693.x
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- Publication type:
- Article
β-Cell research – A decade of rapid growth.
- Published in:
- Diabetes, Obesity & Metabolism, 2009, v. 11, p. iv, doi. 10.1111/j.1463-1326.2009.01143.x
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- Publication type:
- Article
Structural Organization of the Murine D<sub>3</sub> Dopamine Receptor Gene.
- Published in:
- Journal of Neurochemistry, 1995, v. 64, n. 2, p. 482, doi. 10.1046/j.1471-4159.1995.64020482.x
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- Publication type:
- Article
Corrigendum: Structure-based prediction of protein-protein interactions on a genome-wide scale.
- Published in:
- Nature, 2013, v. 495, n. 7439, p. 127, doi. 10.1038/nature11977
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- Publication type:
- Article
Structure-based prediction of protein-protein interactions on a genome-wide scale.
- Published in:
- Nature, 2012, v. 490, n. 7421, p. 556, doi. 10.1038/nature11503
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- Publication type:
- Article
Mutations in insulin-receptor gene in insulin-resistant patients.
- Published in:
- 1990
- By:
- Publication type:
- journal article
MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis.
- Published in:
- Diabetes, 2023, v. 72, n. 12, p. 1781, doi. 10.2337/db23-0314
- By:
- Publication type:
- Article
Susumu Seino, MD, DMSci (1948–2021): A Pioneer in the Biology of Insulin Secretion.
- Published in:
- 2022
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- Publication type:
- Obituary
PPARγ Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment.
- Published in:
- 2020
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- Publication type:
- journal article
2071-P: C2CD4A, Pancreatic Beta-Cell Function, and Type 2 Diabetes Susceptibility.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2071-P
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- Publication type:
- Article
Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes.
- Published in:
- Diabetes, 2019, v. 68, n. 6, p. 1156, doi. 10.2337/db18-1236
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- Publication type:
- Article
Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in Mice.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.
- Published in:
- Nature Communications, 2016, v. 7, n. 8, p. 12631, doi. 10.1038/ncomms12631
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- Publication type:
- Article
Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.
- Published in:
- Nature Communications, 2014, v. 5, n. 10, p. 5190, doi. 10.1038/ncomms6190
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- Publication type:
- Article
FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures.
- Published in:
- Nature Communications, 2014, v. 5, n. 6, p. 4242, doi. 10.1038/ncomms5242
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- Publication type:
- Article
Hepatic FoxO1 Integrates Glucose Utilization and Lipid Synthesis through Regulation of Chrebp O-Glycosylation.
- Published in:
- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047231
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- Publication type:
- Article
InsR/FoxO1 Signaling Curtails Hypothalamic POMC Neuron Number.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031487
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- Publication type:
- Article
Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.
- Published in:
- Nature Medicine, 2013, v. 19, n. 8, p. 1054, doi. 10.1038/nm.3259
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- Publication type:
- Article
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.
- Published in:
- Nature Medicine, 2011, v. 17, n. 8, p. 961, doi. 10.1038/nm.2378
- By:
- Publication type:
- Article
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake.
- Published in:
- Nature Medicine, 2009, v. 15, n. 10, p. 1195, doi. 10.1038/nm.2026
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- Publication type:
- Article
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake.
- Published in:
- Nature Medicine, 2006, v. 12, n. 5, p. 534, doi. 10.1038/nm1392
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- Publication type:
- Article
The tangled path to glucose production.
- Published in:
- Nature Medicine, 2006, v. 12, n. 1, p. 33, doi. 10.1038/nm0106-33
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- Publication type:
- Article
Turning up the heat in the fat cell.
- Published in:
- Nature Medicine, 2004, v. 10, n. 11, p. 1168, doi. 10.1038/nm1104-1168
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- Publication type:
- Article
A note of caution on the Knockout Mouse Project.
- Published in:
- 2004
- By:
- Publication type:
- Letter
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.
- Published in:
- Nature Genetics, 2002, v. 32, n. 2, p. 245, doi. 10.1038/ng890
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- Publication type:
- Article
Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.
- Published in:
- Nature Genetics, 1998, v. 20, n. 3, p. 294, doi. 10.1038/3112
- By:
- Publication type:
- Article
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1a interaction.
- Published in:
- Nature, 2003, v. 423, n. 6939, p. 550, doi. 10.1038/nature01667
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- Publication type:
- Article