Works by Abe, Ikuro

Results: 120

Lincosamide Antibiotics: Structure, Activity, and Biosynthesis.

Published in:

ChemBioChem, 2024, v. 25, n. 6, p. 1, doi. 10.1002/cbic.202300840

By:

Mori, Takahiro;
Abe, Ikuro

Publication type:

Article

Total Synthesis and Structural Revision of Kasumigamide, and Identification of a New Analogue.

Published in:

ChemBioChem, 2020, v. 21, n. 23, p. 3329, doi. 10.1002/cbic.202000409

By:

Kuranaga, Takefumi;
Matsuda, Kenichi;
Takaoka, Masachika;
Tachikawa, Chisato;
Sano, Ayae;
Itoh, Kosei;
Enomoto, Ayumu;
Fujita, Kei;
Abe, Ikuro;
Wakimoto, Toshiyuki

Publication type:

Article

A Tryptophan Prenyltransferase with Broad Substrate Tolerance from Bacillus subtilis subsp. natto.

Published in:

ChemBioChem, 2018, v. 19, n. 13, p. 1396, doi. 10.1002/cbic.201800174

By:

Sugita, Tomotoshi;
Okada, Masahiro;
Nakashima, Yu;
Tian, Tian;
Abe, Ikuro

Publication type:

Article

Chimeric Terpene Synthases Possessing both Terpene Cyclization and Prenyltransfer Activities.

Published in:

ChemBioChem, 2018, v. 19, n. 11, p. 1106, doi. 10.1002/cbic.201800120

By:

Mitsuhashi, Takaaki;
Abe, Ikuro

Publication type:

Article

Identification of Chimeric αβγ Diterpene Synthases Possessing both Type II Terpene Cyclase and Prenyltransferase Activities.

Published in:

ChemBioChem, 2017, v. 18, n. 21, p. 2104, doi. 10.1002/cbic.201700445

By:

Mitsuhashi, Takaaki;
Okada, Masahiro;
Abe, Ikuro

Publication type:

Article

Cover Feature: Identification of Chimeric αβγ Diterpene Synthases Possessing both Type II Terpene Cyclase and Prenyltransferase Activities (ChemBioChem 21/2017).

Published in:

ChemBioChem, 2017, v. 18, n. 21, p. 2080, doi. 10.1002/cbic.201700550

By:

Mitsuhashi, Takaaki;
Okada, Masahiro;
Abe, Ikuro

Publication type:

Article

Structural Diversification of Lyngbyatoxin A by Host-Dependent Heterologous Expression of the tleABC Biosynthetic Gene Cluster.

Published in:

ChemBioChem, 2016, v. 17, n. 15, p. 1407, doi. 10.1002/cbic.201600229

By:

Zhang, Lihan;
Hoshino, Shotaro;
Awakawa, Takayoshi;
Wakimoto, Toshiyuki;
Abe, Ikuro

Publication type:

Article

Biosynthesis of LL-Z1272β: Discovery of a New Member of NRPS-like Enzymes for Aryl-Aldehyde Formation.

Published in:

ChemBioChem, 2016, v. 17, n. 10, p. 904, doi. 10.1002/cbic.201600087

By:

Li, Chang;
Matsuda, Yudai;
Gao, Hao;
Hu, Dan;
Yao, Xin Sheng;
Abe, Ikuro

Publication type:

Article

Three Acyltetronic Acid Derivatives: Noncanonical Cryptic Polyketides from Aspergillus niger Identified by Genome Mining.

Published in:

ChemBioChem, 2014, v. 15, n. 11, p. 1578, doi. 10.1002/cbic.201402172

By:

Yang, Xiao‐Long;
Awakawa, Takayoshi;
Wakimoto, Toshiyuki;
Abe, Ikuro

Publication type:

Article

Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2021, v. 48, n. 3/4, p. 1, doi. 10.1093/jimb/kuab001

By:

Takayoshi Awakawa;
Barra, Lena;
Ikuro Abe

Publication type:

Article

Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2021, p. 1, doi. 10.1093/jimb/kuab001

By:

Awakawa, Takayoshi;
Barra, Lena;
Abe, Ikuro

Publication type:

Article

Introduction to the special issue: “Natural Product Discovery and Development in the Genomic Era: 2019”.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 3/4, p. 249, doi. 10.1007/s10295-019-02138-w

By:

Baltz, Richard H.;
Abe, Ikuro;
Kim, Eung-Soo;
Müller, Rolf;
Van Lanen, Steven G.;
Wright, Gerry

Publication type:

Article

Activation of silent biosynthetic pathways and discovery of novel secondary metabolites in actinomycetes by co-culture with mycolic acid-containing bacteria.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 3/4, p. 363, doi. 10.1007/s10295-018-2100-y

By:

Hoshino, Shotaro;
Onaka, Hiroyasu;
Abe, Ikuro

Publication type:

Article

Structure-function analysis of carrier protein-dependent 2-sulfamoylacetyl transferase in the biosynthesis of altemicidin.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-55265-z

By:

Zhu, Yuhao;
Mori, Takahiro;
Karasawa, Masayuki;
Shirai, Kohei;
Cheng, Wenjiao;
Terada, Tohru;
Awakawa, Takayoshi;
Abe, Ikuro

Publication type:

Article

Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases.

Published in:

Nature Chemistry, 2010, v. 2, n. 10, p. 858, doi. 10.1038/nchem.764

By:

Itoh, Takayuki;
Tokunaga, Kinya;
Matsuda, Yudai;
Fujii, Isao;
Abe, Ikuro;
Ebizuka, Yutaka;
Kushiro, Tetsuo

Publication type:

Article

Enzymatic Formation of Indolactam Scaffold by C−N Bond‐Forming Cytochrome P450 Oxidases in Teleocidin Biosynthesis.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 9, p. 2963, doi. 10.1002/chem.202003899

By:

Morita, Iori;
Mori, Takahiro;
Abe, Ikuro

Publication type:

Article

Structure‐Function Analysis of the S‐Glycosylation Reaction in the Biosynthesis of Lincosamide Antibiotics.

Published in:

Angewandte Chemie, 2023, v. 135, n. 29, p. 1, doi. 10.1002/ange.202304989

By:

Mori, Takahiro;
Sun, Xin;
Kadlcik, Stanislav;
Janata, Jiri;
Abe, Ikuro

Publication type:

Article

Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification.

Published in:

Angewandte Chemie, 2021, v. 133, n. 35, p. 19607, doi. 10.1002/ange.202107884

By:

Yang, Jiali;
Mori, Takahiro;
Wei, Xingxing;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article

Aziridine Formation by a Fe<sup>II</sup>/α‐Ketoglutarate Dependent Oxygenase and 2‐Aminoisobutyrate Biosynthesis in Fungi.

Published in:

Angewandte Chemie, 2021, v. 133, n. 29, p. 15961, doi. 10.1002/ange.202104644

By:

Bunno, Reito;
Awakawa, Takayoshi;
Mori, Takahiro;
Abe, Ikuro

Publication type:

Article

Innenrücktitelbild: One Polyketide Synthase, Two Distinct Products: Trans‐Acting Enzyme‐Controlled Product Divergence in Calbistrin Biosynthesis (Angew. Chem. 16/2021).

Published in:

Angewandte Chemie, 2021, v. 133, n. 16, p. 9227, doi. 10.1002/ange.202102305

By:

Tao, Hui;
Mori, Takahiro;
Wei, Xingxing;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article

One Polyketide Synthase, Two Distinct Products: Trans‐Acting Enzyme‐Controlled Product Divergence in Calbistrin Biosynthesis.

Published in:

Angewandte Chemie, 2021, v. 133, n. 16, p. 8933, doi. 10.1002/ange.202016525

By:

Tao, Hui;
Mori, Takahiro;
Wei, Xingxing;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article

Exploiting the Potential of Meroterpenoid Cyclases to Expand the Chemical Space of Fungal Meroterpenoids.

Published in:

Angewandte Chemie, 2020, v. 132, n. 52, p. 23980, doi. 10.1002/ange.202011171

By:

Mitsuhashi, Takaaki;
Barra, Lena;
Powers, Zachary;
Kojasoy, Volga;
Cheng, Andrea;
Yang, Feng;
Taniguchi, Yoshimasa;
Kikuchi, Takashi;
Fujita, Makoto;
Tantillo, Dean J.;
Porco, John A.;
Abe, Ikuro

Publication type:

Article

Biosynthesis of Biscognienyne B Involving a Cytochrome P450‐Dependent Alkynylation.

Published in:

Angewandte Chemie, 2020, v. 132, n. 32, p. 13633, doi. 10.1002/ange.202004364

By:

Lv, Jian‐Ming;
Gao, Yao‐Hui;
Zhao, Huan;
Awakawa, Takayoshi;
Liu, Ling;
Chen, Guo‐Dong;
Yao, Xin‐Sheng;
Hu, Dan;
Abe, Ikuro;
Gao, Hao

Publication type:

Article

Frontispiz: Exploiting a C–N Bond Forming Cytochrome P450 Monooxygenase for C–S Bond Formation.

Published in:

Angewandte Chemie, 2020, v. 132, n. 10, p. 1, doi. 10.1002/ange.202081062

By:

Morita, Iori;
Mori, Takahiro;
Mitsuhashi, Takaaki;
Hoshino, Shotaro;
Taniguchi, Yoshimasa;
Kikuchi, Takashi;
Nagae, Kei;
Nasu, Norihiro;
Fujita, Makoto;
Ohwada, Tomohiko;
Abe, Ikuro

Publication type:

Article

Exploiting a C–N Bond Forming Cytochrome P450 Monooxygenase for C–S Bond Formation.

Published in:

Angewandte Chemie, 2020, v. 132, n. 10, p. 4017, doi. 10.1002/ange.201916269

By:

Morita, Iori;
Mori, Takahiro;
Mitsuhashi, Takaaki;
Hoshino, Shotaro;
Taniguchi, Yoshimasa;
Kikuchi, Takashi;
Nagae, Kei;
Nasu, Norihiro;
Fujita, Makoto;
Ohwada, Tomohiko;
Abe, Ikuro

Publication type:

Article

Biomimetic Synthesis of Meroterpenoids by Dearomatization‐Driven Polycyclization.

Published in:

Angewandte Chemie, 2019, v. 131, n. 45, p. 16287, doi. 10.1002/ange.201910710

By:

Powers, Zachary;
Scharf, Adam;
Cheng, Andrea;
Yang, Feng;
Himmelbauer, Martin;
Mitsuhashi, Takaaki;
Barra, Lena;
Taniguchi, Yoshimasa;
Kikuchi, Takashi;
Fujita, Makoto;
Abe, Ikuro;
Porco, John A.

Publication type:

Article

Computational Studies on Biosynthetic Carbocation Rearrangements Leading to Quiannulatene: Initial Conformation Regulates Biosynthetic Route, Stereochemistry, and Skeleton Type.

Published in:

Angewandte Chemie, 2018, v. 130, n. 45, p. 14968, doi. 10.1002/ange.201807139

By:

Sato, Hajime;
Mitsuhashi, Takaaki;
Yamazaki, Mami;
Abe, Ikuro;
Uchiyama, Masanobu

Publication type:

Article

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27971-z

By:

Wang, Xiao-Hui;
Gao, Bo-Wen;
Nakashima, Yu;
Mori, Takahiro;
Zhang, Zhong-Xiu;
Kodama, Takeshi;
Lee, Yuan-E;
Zhang, Ze-Kun;
Wong, Chin-Piow;
Liu, Qian-Qian;
Qi, Bo-Wen;
Wang, Juan;
Li, Jun;
Liu, Xiao;
Abe, Ikuro;
Morita, Hiroyuki;
Tu, Peng-Fei;
Shi, She-Po

Publication type:

Article

Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27636-3

By:

Tao, Hui;
Mori, Takahiro;
Chen, Heping;
Lyu, Shuang;
Nonoyama, Akihito;
Lee, Shoukou;
Abe, Ikuro

Publication type:

Article

C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26585-1

By:

Mori, Takahiro;
Kumano, Takuto;
He, Haibing;
Watanabe, Satomi;
Senda, Miki;
Moriya, Toshio;
Adachi, Naruhiko;
Hori, Sanae;
Terashita, Yuzu;
Kawasaki, Masato;
Hashimoto, Yoshiteru;
Awakawa, Takayoshi;
Senda, Toshiya;
Abe, Ikuro;
Kobayashi, Michihiko

Publication type:

Article

Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24685-6

By:

Mori, Takahiro;
Zhai, Rui;
Ushimaru, Richiro;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article

Novel type III polyketide synthases from Aloe arborescens.

Published in:

FEBS Journal, 2009, v. 276, n. 8, p. 2391, doi. 10.1111/j.1742-4658.2009.06971.x

By:

Mizuuchi, Yuusuke;
Shi, She-Po;
Wanibuchi, Kiyofumi;
Kojima, Akiko;
Morita, Hiroyuki;
Noguchi, Hiroshi;
Abe, Ikuro

Publication type:

Article

An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata.

Published in:

FEBS Journal, 2007, v. 274, n. 4, p. 1073, doi. 10.1111/j.1742-4658.2007.05656.x

By:

Wanibuchi, Kiyofumi;
Ping Zhang;
Abe, Tsuyoshi;
Morita, Hiroyuki;
Kohno, Toshiyuki;
Chen, Guoshen;
Noguchi, Hiroshi;
Abe, Ikuro

Publication type:

Article

Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase.

Published in:

FEBS Journal, 2006, v. 273, n. 1, p. 208, doi. 10.1111/j.1742-4658.2005.05059.x

By:

Abe, Ikuro;
Watanabe, Tatsuya;
Lou, Weiwei;
Noguchi, Hiroshi

Publication type:

Article

Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 2, p. 395, doi. 10.1172/JCI20797

By:

Mori, Masayuki;
Li, Guixin;
Abe, Ikuro;
Nakayama, Jun;
Guo, Zhanjun;
Sawashita, Jinko;
Ugawa, Tohru;
Nishizono, Shoko;
Serikawa, Tadao;
Higuchi, Keiichi;
Shumiya, Seigo

Publication type:

Article

Reconstitution of Polyketide-Derived Meroterpenoid Biosynthetic Pathway in Aspergillus oryzae.

Published in:

Journal of Fungi, 2021, v. 7, n. 6, p. 1, doi. 10.3390/jof7060486

By:

Takayoshi Awakawa;
Ikuro Abe

Publication type:

Article

Expression, purification and crystallization of a plant polyketide cyclase from Cannabis sativa.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 12, p. 1470, doi. 10.1107/S2053230X15020385

By:

Yang, Xinmei;
Matsui, Takashi;
Mori, Takahiro;
Taura, Futoshi;
Noguchi, Hiroshi;
Abe, Ikuro;
Morita, Hiroyuki

Publication type:

Article

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164468

By:

Nakashima, Yu;
Egami, Yoko;
Kimura, Miki;
Wakimoto, Toshiyuki;
Abe, Ikuro

Publication type:

Article

Structure-function analysis of 2-sulfamoylacetic acid synthase in altemicidin biosynthesis.

Published in:

Journal of Antibiotics, 2025, v. 78, n. 3, p. 149, doi. 10.1038/s41429-024-00798-0

By:

Mori, Takahiro;
Sakurada, Kosuke;
Awakawa, Takayoshi;
He, Haibin;
Ushimaru, Richiro;
Abe, Ikuro

Publication type:

Article

Biosynthetic studies on teleocidins in Streptomyces.

Published in:

Journal of Antibiotics, 2018, v. 71, n. 9, p. 763, doi. 10.1038/s41429-018-0069-4

By:

Abe, Ikuro

Publication type:

Article

Umezawamides, new bioactive polycyclic tetramate macrolactams isolated from a combined-culture of Umezawaea sp. and mycolic acid-containing bacterium.

Published in:

Journal of Antibiotics, 2018, v. 71, n. 7, p. 653, doi. 10.1038/s41429-018-0040-4

By:

Hoshino, Shotaro;
Wong, Chin Piow;
Ozeki, Masahiro;
Zhang, Huiping;
Hayashi, Fumiaki;
Awakawa, Takayoshi;
Asamizu, Shumpei;
Onaka, Hiroyasu;
Abe, Ikuro

Publication type:

Article

Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823.

Published in:

Journal of Antibiotics, 2015, v. 68, n. 5, p. 342, doi. 10.1038/ja.2014.147

By:

Hoshino, Shotaro;
Zhang, Lihan;
Awakawa, Takayoshi;
Wakimoto, Toshiyuki;
Onaka, Hiroyasu;
Abe, Ikuro

Publication type:

Article

Alkylresorcinol Synthases Expressed in Sorghum bicolor Root Hairs Play an Essential Role in the Biosynthesis of the Allelopathic Benzoquinone Sorgoleone.

Published in:

Plant Cell, 2010, v. 22, n. 3, p. 867, doi. 10.1105/tpc.109.072397

By:

Cook, Daniel;
Rimando, Agnes M.;
Clemente, Thomas E.;
Schröder, Joachim;
Dayan, Franck E.;
Nanayakkara, N.P. Dhammika;
Pan, Zhiqiang;
Noonan, Brice P.;
Fishbein, Mark;
Abe, Ikuro;
Duke, Stephen O.;
Baerson, Scott R.

Publication type:

Article

A New Monoterpene from the Rhizomes of Alpinia galanga and Its Anti‐Vpr Activity.

Published in:

Chemistry & Biodiversity, 2021, v. 18, n. 10, p. 1, doi. 10.1002/cbdv.202100401

By:

Nam Hoang, Nhat;
Kodama, Takeshi;
Nwet Win, Nwet;
Prema;
Minh Do, Kiep;
Abe, Ikuro;
Morita, Hiroyuki

Publication type:

Article

Discovery of (±)‐Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 26, p. 1, doi. 10.1002/anie.202403963

By:

Meng, Ling‐Hong;
Awakawa, Takayoshi;
Li, Xiao‐Ming;
Quan, Zhiyang;
Yang, Sui‐Qun;
Wang, Bin‐Gui;
Abe, Ikuro

Publication type:

Article

Structure‐Function Analysis of the S‐Glycosylation Reaction in the Biosynthesis of Lincosamide Antibiotics.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 29, p. 1, doi. 10.1002/anie.202304989

By:

Mori, Takahiro;
Sun, Xin;
Kadlcik, Stanislav;
Janata, Jiri;
Abe, Ikuro

Publication type:

Article

Structural Basis for Isomerization Reactions in Fungal Tetrahydroxanthone Biosynthesis and Diversification.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 35, p. 19458, doi. 10.1002/anie.202107884

By:

Yang, Jiali;
Mori, Takahiro;
Wei, Xingxing;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article

Aziridine Formation by a Fe<sup>II</sup>/α‐Ketoglutarate Dependent Oxygenase and 2‐Aminoisobutyrate Biosynthesis in Fungi.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 29, p. 15827, doi. 10.1002/anie.202104644

By:

Bunno, Reito;
Awakawa, Takayoshi;
Mori, Takahiro;
Abe, Ikuro

Publication type:

Article

Inside Back Cover: One Polyketide Synthase, Two Distinct Products: Trans‐Acting Enzyme‐Controlled Product Divergence in Calbistrin Biosynthesis (Angew. Chem. Int. Ed. 16/2021).

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 16, p. 9143, doi. 10.1002/anie.202102305

By:

Tao, Hui;
Mori, Takahiro;
Wei, Xingxing;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article

One Polyketide Synthase, Two Distinct Products: Trans‐Acting Enzyme‐Controlled Product Divergence in Calbistrin Biosynthesis.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 16, p. 8851, doi. 10.1002/anie.202016525

By:

Tao, Hui;
Mori, Takahiro;
Wei, Xingxing;
Matsuda, Yudai;
Abe, Ikuro

Publication type:

Article