Works by Abdel-Sayed, Philippe

Results: 39

Laboratory-Generated Autologous Skin Substitutes for Burn Treatment in Europe: Narrative Review, Experts' Opinion, and Legal Considerations.

Published in:

European Burn Journal (EBJ), 2025, v. 6, n. 2, p. 30, doi. 10.3390/ebj6020030

By:

Auxenfans, Celine;
Valencia, Rocio G.;
Abdel-Sayed, Philippe;
Alaminos, Miguel;
Brunet, Jean-François;
Campos, Fernando;
Chato-Astrain, Jesus;
Carmona, Gloria;
de Buys Roessingh, Anthony;
Droz-Georget, Stephanie;
Farkas, Melinda;
Fernandez Gonzalez, Ana;
Gönczi, Enikö;
Huss, Fredrik;
Hartmann, Bernd;
Heusi, Barbara;
Karström, Alexandra;
Moiemen, Naiem;
Sartoris, Giulia;
Spranger, Antje

Publication type:

Article

Process Optimization and Efficacy Assessment of Standardized PRP for Tendinopathies in Sports Medicine: Retrospective Study of Clinical Files and GMP Manufacturing Records in a Swiss University Hospital.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 4, p. 409, doi. 10.3390/bioengineering10040409

By:

Sebbagh, Patrick;
Hirt-Burri, Nathalie;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Gremeaux, Vincent;
Laurent, Alexis;
Applegate, Lee Ann;
Gremion, Gerald

Publication type:

Article

Current Status of PRP Manufacturing Requirements & European Regulatory Frameworks: Practical Tools for the Appropriate Implementation of PRP Therapies in Musculoskeletal Regenerative Medicine.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 3, p. 292, doi. 10.3390/bioengineering10030292

By:

Sebbagh, Patrick;
Cannone, Alessandro;
Gremion, Gerald;
Gremeaux, Vincent;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Michetti, Murielle;
Abdel-Sayed, Philippe;
Laurent, Alexis;
Wardé, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Back to the Cradle of Cytotherapy: Integrating a Century of Clinical Research and Biotechnology-Based Manufacturing for Modern Tissue-Specific Cellular Treatments in Switzerland.

Published in:

Bioengineering (Basel), 2021, v. 8, n. 12, p. 1, doi. 10.3390/bioengineering8120221

By:

Laurent, Alexis;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Laurent, Philippe;
Laurent, Elénie;
Michetti, Murielle;
de Buys Roessingh, Anthony;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Design optimization of bidirectional arterial perfusion cannula.

Published in:

2021

By:

Abdel-Sayed, Saad;
Ferrari, Enrico;
Abdel-Sayed, Philippe;
Wilhelm, Markus;
von Segesser, Ludwig-Karl;
Berdajs, Denis

Publication type:

journal article

Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calciumÂ signaling.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.72068

By:

Nasrollahzadeh, Naser;
Karami, Peyman;
Jian Wang;
Bagheri, Lida;
Yanheng Guo;
Abdel-Sayed, Philippe;
Laurent-Applegate, Lee;
Pioletti, Dominique P.

Publication type:

Article

Corrigendum: Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages.

Published in:

Scientific Reports, 2016, p. 23872, doi. 10.1038/srep23872

By:

Abdel-Sayed, Philippe;
Kaeppeli, Ariane;
Siriwardena, Thissa;
Darbre, Tamis;
Perron, Karl;
Jafari, Paris;
Reymond, Jean-Louis;
Pioletti, Dominique P.;
Applegate, Lee Ann

Publication type:

Article

Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages.

Published in:

Scientific Reports, 2016, p. 22020, doi. 10.1038/srep22020

By:

Abdel-Sayed, Philippe;
Kaeppli, Ariane;
Siriwardena, Thissa;
Darbre, Tamis;
Perron, Karl;
Jafari, Paris;
Reymond, Jean-Louis;
Pioletti, Dominique P.;
Applegate, Lee Ann

Publication type:

Article

Dual Functionalization of Hyaluronan Dermal Fillers with Vitamin B3: Efficient Combination of Bio-Stimulation Properties with Hydrogel System Resilience Enhancement.

Published in:

Gels (2310-2861), 2024, v. 10, n. 6, p. 361, doi. 10.3390/gels10060361

By:

Porcello, Alexandre;
Chemali, Michèle;
Marques, Cíntia;
Scaletta, Corinne;
Lourenço, Kelly;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann;
Laurent, Alexis

Publication type:

Article

Ex Vivo Functional Benchmarking of Hyaluronan-Based Osteoarthritis Viscosupplement Products: Comprehensive Assessment of Rheological, Lubricative, Adhesive, and Stability Attributes.

Published in:

Gels (2310-2861), 2023, v. 9, n. 10, p. 808, doi. 10.3390/gels9100808

By:

Porcello, Alexandre;
Hadjab, Farid;
Ajouaou, Maryam;
Philippe, Virginie;
Martin, Robin;
Abdel-Sayed, Philippe;
Hirt-Burri, Nathalie;
Scaletta, Corinne;
Raffoul, Wassim;
Applegate, Lee Ann;
Allémann, Eric;
Jordan, Olivier;
Laurent, Alexis

Publication type:

Article

Pilot Clinical Safety and Efficacy Evaluation of a Topical 3% Tranexamic Acid Cream and Serum Protocol for Managing Facial Hyperpigmentation in Caucasian Patients.

Published in:

Cosmetics (2079-9284), 2024, v. 11, n. 5, p. 168, doi. 10.3390/cosmetics11050168

By:

Hsin, Sarah;
Lourenço, Kelly;
Porcello, Alexandre;
Marques, Cíntia;
Rodriguez, Clara;
Raffoul, Wassim;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Hadjab, Basste;
Applegate, Lee Ann;
Laurent, Alexis

Publication type:

Article

Medicalized Aesthetic Uses of Exosomes and Cell Culture-Conditioned Media: Opening an Advanced Care Era for Biologically Inspired Cutaneous Prejuvenation and Rejuvenation.

Published in:

Cosmetics (2079-9284), 2024, v. 11, n. 5, p. 154, doi. 10.3390/cosmetics11050154

By:

Rodriguez, Clara;
Porcello, Alexandre;
Chemali, Michèle;
Raffoul, Wassim;
Marques, Cíntia;
Scaletta, Corinne;
Lourenço, Kelly;
Abdel-Sayed, Philippe;
Applegate, Lee Ann;
Pelissier Vatter, Fanny;
Laurent, Alexis

Publication type:

Article

Optimized Manufacture of Lyophilized Dermal Fibroblasts for Next-Generation Off-the-Shelf Progenitor Biological Bandages in Topical Post-Burn Regenerative Medicine.

Published in:

Biomedicines, 2021, v. 9, n. 8, p. 1072, doi. 10.3390/biomedicines9081072

By:

Laurent, Alexis;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Michetti, Murielle;
Flahaut, Marjorie;
Simon, Jeanne-Pascale;
Roessingh, Anthony de Buys;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation.

Published in:

Biomedicines, 2021, v. 9, n. 4, p. 380, doi. 10.3390/biomedicines9040380

By:

Laurent, Alexis;
Abdel-Sayed, Philippe;
Grognuz, Anthony;
Scaletta, Corinne;
Hirt-Burri, Nathalie;
Michetti, Murielle;
de Buys Roessingh, Anthony S.;
Raffoul, Wassim;
Kronen, Peter;
Nuss, Katja;
von Rechenberg, Brigitte;
Applegate, Lee Ann;
Darwiche, Salim E.

Publication type:

Article

Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 2, p. 250, doi. 10.3390/biom11020250

By:

Laurent, Alexis;
Abdel-Sayed, Philippe;
Ducrot, Aurélie;
Hirt-Burri, Nathalie;
Scaletta, Corinne;
Jaccoud, Sandra;
Nuss, Katja;
de Buys Roessingh, Anthony S.;
Raffoul, Wassim;
Pioletti, Dominique;
von Rechenberg, Brigitte;
Applegate, Lee Ann;
Darwiche, Salim

Publication type:

Article

Human Platelet Lysate as an Alternative to Autologous Serum for Human Chondrocyte Clinical Use.

Published in:

Cartilage, 2021, v. 13, p. 509S, doi. 10.1177/19476035211035433

By:

Philippe, Virginie;
Laurent, Alexis;
Abdel-Sayed, Philippe;
Hirt-Burri, Nathalie;
Ann Applegate, Lee;
Martin, Robin

Publication type:

Article

Primary Chondroprogenitors: Standardized & Versatile Allogeneic Cytotherapeutics.

Published in:

Encyclopedia, 2023, v. 3, n. 2, p. 622, doi. 10.3390/encyclopedia3020045

By:

Laurent, Alexis;
Jeannerat, Annick;
Peneveyre, Cédric;
Scaletta, Corinne;
Philippe, Virginie;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Martin, Robin;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Primary Progenitor Tenocytes: Cytotherapeutics and Cell-Free Derivatives.

Published in:

Encyclopedia, 2023, v. 3, n. 1, p. 340, doi. 10.3390/encyclopedia3010021

By:

Laurent, Alexis;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Biotechnology and Cytotherapeutics: The Swiss Progenitor-Cell Transplantation Program.

Published in:

Encyclopedia, 2022, v. 2, n. 1, p. 336, doi. 10.3390/encyclopedia2010021

By:

Laurent, Alexis;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Michetti, Murielle;
de Buys Roessingh, Anthony;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Industrial Biotechnology Conservation Processes: Similarities with Natural Long-Term Preservation of Biological Organisms.

Published in:

BioTech, 2023, v. 12, n. 1, p. 15, doi. 10.3390/biotech12010015

By:

Laurent, Alexis;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 3, p. 201, doi. 10.3390/ph14030201

By:

Al-Dourobi, Karim;
Laurent, Alexis;
Deghayli, Lina;
Flahaut, Marjorie;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Michetti, Murielle;
Waselle, Laurent;
Simon, Jeanne-Pascale;
El Ezzi, Oumama;
Raffoul, Wassim;
Applegate, Lee Ann;
Hirt-Burri, Nathalie;
Roessingh, Anthony S de Buys;
Hanawa, Takehisa

Publication type:

Article

Corrigendum to: Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.

Published in:

2021

By:

Chemali, Michèle;
Laurent, Alexis;
Scaletta, Corinne;
Waselle, Laurent;
Simon, Jeanne-Pascale;
Michetti, Murielle;
Brunet, Jean-François;
Flahaut, Marjorie;
Hirt-Burri, Nathalie;
Raffoul, Wassim;
Applegate, Lee Ann;
Roessingh, Anthony S de Buys;
Abdel-Sayed, Philippe;
de Buys Roessingh, Anthony S

Publication type:

corrected article

Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.

Published in:

2021

By:

Chemali, Michèle;
Laurent, Alexis;
Scaletta, Corinne;
Waselle, Laurent;
Simon, Jeanne-Pascale;
Michetti, Murielle;
Brunet, Jean-François;
Flahaut, Marjorie;
Hirt-Burri, Nathalie;
Raffoul, Wassim;
Applegate, Lee Ann;
Roessingh, Anthony S de Buys;
Abdel-Sayed, Philippe;
de Buys Roessingh, Anthony S

Publication type:

journal article

Comparison of radial deformability of stent posts of different aortic bioprostheses†.

Published in:

Interactive Cardiovascular & Thoracic Surgery, 2013, v. 16, n. 2, p. 129, doi. 10.1093/icvts/ivs457

By:

Kalejs, Martins;
Lacis, Romans;
Kasyanov, Vladimir;
Ozolanta, Iveta;
Abdel Sayed, Philippe;
Stradins, Peteris;
von Segesser, Ludwig Karl

Publication type:

Article

Sustainable Primary Cell Banking for Topical Compound Cytotoxicity Assays: Protocol Validation on Novel Biocides and Antifungals for Optimized Burn Wound Care.

Published in:

European Burn Journal (EBJ), 2024, v. 5, n. 3, p. 249, doi. 10.3390/ebj5030024

By:

Liao, Zhifeng;
Laurent, Nicolas;
Hirt-Burri, Nathalie;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Luo, Shengkang;
Krysan, Damian J.;
Laurent, Alexis;
Applegate, Lee Ann

Publication type:

Article

Retrospective Analysis of Autologous Chondrocyte-Based Cytotherapy Production for Clinical Use: GMP Process-Based Manufacturing Optimization in a Swiss University Hospital.

Published in:

Cells (2073-4409), 2022, v. 11, n. 6, p. 1016, doi. 10.3390/cells11061016

By:

Philippe, Virginie;
Laurent, Alexis;
Hirt-Burri, Nathalie;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Schneebeli, Valentine;
Michetti, Murielle;
Brunet, Jean-François;
Applegate, Lee Ann;
Martin, Robin

Publication type:

Article

Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative Medicine.

Published in:

Cells (2073-4409), 2021, v. 10, n. 10, p. 2526, doi. 10.3390/cells10102526

By:

Laurent, Alexis;
Abdel-Sayed, Philippe;
Hirt-Burri, Nathalie;
Scaletta, Corinne;
Michetti, Murielle;
de Buys Roessingh, Anthony;
Raffoul, Wassim;
Applegate, Lee Ann

Publication type:

Article

Effect of blood viscosity on the performance of virtually wall-less venous cannulas.

Published in:

Perfusion, 2020, v. 35, n. 5, p. 393, doi. 10.1177/0267659119885514

By:

Abdel-Sayed, Saad;
Abdel-Sayed, Philippe;
Berdaj, Denis;
Ferrari, Enrico;
Halbe, Maximilian;
von Segesser, Ludwig Karl;
Maisano, Francesco

Publication type:

Article

In Vitro Evaluation and Clinical Effects of a Regenerative Complex with Non-Cross-Linked Hyaluronic Acid and a High-Molecular-Weight Polynucleotide for Periorbital Treatment.

Published in:

Polymers (20734360), 2025, v. 17, n. 5, p. 638, doi. 10.3390/polym17050638

By:

Abuyousif, Hanadi Sami;
Porcello, Alexandre;
Cerrano, Marco;
Marques, Cíntia;
Scaletta, Corinne;
Lourenço, Kelly;
Abdel-Sayed, Philippe;
Chemali, Michèle;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann;
Laurent, Alexis E.

Publication type:

Article

Banked Primary Progenitor Cells for Allogeneic Intervertebral Disc (IVD) Therapy: Preclinical Qualification and Functional Optimization within a Cell Spheroid Formulation Process.

Published in:

Pharmaceutics, 2024, v. 16, n. 10, p. 1274, doi. 10.3390/pharmaceutics16101274

By:

Jeannerat, Annick;
Peneveyre, Cédric;
Jaccoud, Sandra;
Philippe, Virginie;
Scaletta, Corinne;
Hirt-Burri, Nathalie;
Abdel-Sayed, Philippe;
Martin, Robin;
Applegate, Lee Ann;
Pioletti, Dominique P.;
Laurent, Alexis

Publication type:

Article

Cutaneous Cell Therapy Manufacturing Timeframe Rationalization: Allogeneic Off-the-Freezer Fibroblasts for Dermo-Epidermal Combined Preparations (DE-FE002-SK2) in Burn Care.

Published in:

Pharmaceutics, 2023, v. 15, n. 9, p. 2334, doi. 10.3390/pharmaceutics15092334

By:

Chen, Xi;
Laurent, Alexis;
Liao, Zhifeng;
Jaccoud, Sandra;
Abdel-Sayed, Philippe;
Flahaut, Marjorie;
Scaletta, Corinne;
Raffoul, Wassim;
Applegate, Lee Ann;
Hirt-Burri, Nathalie

Publication type:

Article

Autologous and Allogeneic Cytotherapies for Large Knee (Osteo)Chondral Defects: Manufacturing Process Benchmarking and Parallel Functional Qualification.

Published in:

Pharmaceutics, 2023, v. 15, n. 9, p. 2333, doi. 10.3390/pharmaceutics15092333

By:

Philippe, Virginie;
Jeannerat, Annick;
Peneveyre, Cédric;
Jaccoud, Sandra;
Scaletta, Corinne;
Hirt-Burri, Nathalie;
Abdel-Sayed, Philippe;
Raffoul, Wassim;
Darwiche, Salim;
Applegate, Lee Ann;
Martin, Robin;
Laurent, Alexis

Publication type:

Article

Bio-Enhanced Neoligaments Graft Bearing FE002 Primary Progenitor Tenocytes: Allogeneic Tissue Engineering & Surgical Proofs-of-Concept for Hand Ligament Regenerative Medicine.

Published in:

Pharmaceutics, 2023, v. 15, n. 7, p. 1873, doi. 10.3390/pharmaceutics15071873

By:

Jeannerat, Annick;
Meuli, Joachim;
Peneveyre, Cédric;
Jaccoud, Sandra;
Chemali, Michèle;
Thomas, Axelle;
Liao, Zhifeng;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Hirt-Burri, Nathalie;
Applegate, Lee Ann;
Raffoul, Wassim;
Laurent, Alexis

Publication type:

Article

Thermo-Responsive Hyaluronan-Based Hydrogels Combined with Allogeneic Cytotherapeutics for the Treatment of Osteoarthritis.

Published in:

Pharmaceutics, 2023, v. 15, n. 5, p. 1528, doi. 10.3390/pharmaceutics15051528

By:

Porcello, Alexandre;
Gonzalez-Fernandez, Paula;
Jeannerat, Annick;
Peneveyre, Cédric;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann;
Allémann, Eric;
Laurent, Alexis;
Jordan, Olivier

Publication type:

Article

Retrospectives on Three Decades of Safe Clinical Experience with Allogeneic Dermal Progenitor Fibroblasts: High Versatility in Topical Cytotherapeutic Care.

Published in:

Pharmaceutics, 2023, v. 15, n. 1, p. 184, doi. 10.3390/pharmaceutics15010184

By:

Laurent, Alexis;
Rey, Marina;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Michetti, Murielle;
Flahaut, Marjorie;
Raffoul, Wassim;
de Buys Roessingh, Anthony;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article

Combination of Hyaluronan and Lyophilized Progenitor Cell Derivatives: Stabilization of Functional Hydrogel Products for Therapeutic Management of Tendinous Tissue Disorders.

Published in:

Pharmaceutics, 2021, v. 13, n. 12, p. 2196, doi. 10.3390/pharmaceutics13122196

By:

Laurent, Alexis;
Porcello, Alexandre;
Fernandez, Paula Gonzalez;
Jeannerat, Annick;
Peneveyre, Cédric;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Hirt-Burri, Nathalie;
Michetti, Murielle;
de Buys Roessingh, Anthony;
Raffoul, Wassim;
Allémann, Eric;
Jordan, Olivier;
Applegate, Lee Ann

Publication type:

Article

Manufacturing Process Development for Bison bison Organ-Specific Lyophilized Extracts: Formulation and Benchmarking of Antioxidant Activities for Nutraceutical Preparations.

Published in:

Nutraceuticals (1661-3821), 2025, v. 5, n. 1, p. 6, doi. 10.3390/nutraceuticals5010006

By:

Porcello, Alexandre;
Girardet, Kim;
Hadjab, Basste;
Lourenço, Kelly;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Hirt-Burri, Nathalie;
Applegate, Lee Ann;
Laurent, Alexis E.

Publication type:

Article

Mechanistic Insights into the Multiple Functions of Niacinamide: Therapeutic Implications and Cosmeceutical Applications in Functional Skincare Products.

Published in:

Antioxidants, 2024, v. 13, n. 4, p. 425, doi. 10.3390/antiox13040425

By:

Marques, Cíntia;
Hadjab, Farid;
Porcello, Alexandre;
Lourenço, Kelly;
Scaletta, Corinne;
Abdel-Sayed, Philippe;
Hirt-Burri, Nathalie;
Applegate, Lee Ann;
Laurent, Alexis

Publication type:

Article

Lyophilized Progenitor Tenocyte Extracts: Sterilizable Cytotherapeutic Derivatives with Antioxidant Properties and Hyaluronan Hydrogel Functionalization Effects.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 163, doi. 10.3390/antiox12010163

By:

Laurent, Alexis;
Porcello, Alexandre;
Jeannerat, Annick;
Peneveyre, Cédric;
Coeur, Agathe;
Abdel-Sayed, Philippe;
Scaletta, Corinne;
Michetti, Murielle;
de Buys Roessingh, Anthony;
Jordan, Olivier;
Allémann, Eric;
Raffoul, Wassim;
Hirt-Burri, Nathalie;
Applegate, Lee Ann

Publication type:

Article