Works matching AU Abdel-Aziz, Alaa A-M.

Results: 35

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin.

Published in:

Molecules, 2022, v. 27, n. 1, p. 90, doi. 10.3390/molecules27010090

By:

Abdalla, Ashraf N.;
Di Stefano, Miriana;
Poli, Giulio;
Tuccinardi, Tiziano;
Bader, Ammar;
Vassallo, Antonio;
Abdallah, Mohamed E.;
El-Readi, Mahmoud Zaki;
Refaat, Bassem;
Algarni, Alanood S.;
Ahmad, Rizwan;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Alqathama, Aljawharah

Publication type:

Article

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2220, doi. 10.3390/molecules25092220

By:

Abdalla, Ashraf N.;
Abdallah, Mohamed E.;
Aslam, Akhmed;
Bader, Ammar;
Vassallo, Antonio;
Tommasi, Nunziatina De;
Malki, Waleed H.;
Gouda, Ahmed M.;
Mukhtar, Mohammed H.;
El-Readi, Mahmoud Zaki;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Tylkowski, Bartosz;
Bajek, Anna;
Roszkowski, Krzysztof

Publication type:

Article

Hirshfeld Surface, Molecular Docking Study, Spectroscopic Characterization and NLO Profile of 2-Methoxy-4,6- Diphenylnicotinonitrile.

Published in:

ChemistrySelect, 2019, v. 4, n. 33, p. 9857, doi. 10.1002/slct.201902391

By:

Gökce, Halil;
Sert, Yusuf;
Alpaslan, Gökhan;
El-Azab, Adel S.;
Alanazi, Mohammed M.;
Al-Agamy, Mohamed H. M.;
Abdel-Aziz, Alaa A. -M.

Publication type:

Article

Structural, Spectroscopic, Electronic and Molecular Docking Studies on (11R,12 S)‐16‐Aminotetracyclo[6.6.2.02,7.09,14]hexadeca‐2(7),3,5,9(14),10,12‐hexaen‐15‐ol.

Published in:

ChemistrySelect, 2019, v. 4, n. 3, p. 825, doi. 10.1002/slct.201803732

By:

Kaya, Serdal;
Gökce, Halil;
El‐Azab, Adel S.;
Sert, Yusuf;
Alanazi, Mohammed M.;
Öztürk, Nuri;
Al‐Agamy, Mohamed H. M.;
Abdel‐Aziz, Alaa A.‐M.

Publication type:

Article

4‐[(1, 3‐Dioxoisoindolin‐2‐yl)methyl]benzenesulfonamide: Full Structural and Spectroscopic Characterization and Molecular Docking with Carbonic Anhydrase II.

Published in:

ChemistrySelect, 2018, v. 3, n. 35, p. 10113, doi. 10.1002/slct.201802484

By:

Gökce, Halil;
Öztürk, Nuri;
Sert, Yusuf;
El‐Azab, Adel S.;
A. AlSaif, Nawaf;
Abdel‐Aziz, Alaa A.‐M.

Publication type:

Article

Crystal, molecular structure, and conformational preferences of 3-(2-(4-morpholinophenyl)-2-oxoethyl)-5,5-diphenylimidazolidine-2,4-dione.

Published in:

Molecular Crystals & Liquid Crystals, 2016, v. 631, n. 1, p. 144, doi. 10.1080/15421406.2016.1149027

By:

Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
El-Azab, Adel S.;
Khalil, Nasr Y.;
Fun, Hoong-Kun;
El-Sherbeny, Magda A.

Publication type:

Article

Crystal structure of 6-iodo-3-phenyl-2-propylquinazolin-4(3H)-one, C17H15IN2O.

Published in:

Zeitschrift für Kristallographie / New Crystal Structures, 2020, v. 235, n. 2, p. 489, doi. 10.1515/ncrs-2019-0788

By:

El-Azab, Adel S.;
Ghabbour, Hazem A.;
Abdel-Aziz, Alaa A.-M.;
Alkahtani, Hamad M.

Publication type:

Article

Crystal structure of (E)-N′-((4-aminophenyl)sulfonyl)-N,N-dimethylformimidamide, C9H13N3O2S.

Published in:

Zeitschrift für Kristallographie / New Crystal Structures, 2020, v. 235, n. 2, p. 483, doi. 10.1515/ncrs-2019-0781

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Ghabbour, Hazem A.;
Obaidullaha, Ahmad J.

Publication type:

Article

Synthesis and In Vitro Anticancer Activity of Novel 4-Aryl-3-(4-methoxyphenyl)-1-phenyl-1 H -pyrazolo[3,4- b ]pyridines Arrest Cell Cycle and Induce Cell Apoptosis by Inhibiting CDK2 and/or CDK9.

Published in:

Molecules, 2023, v. 28, n. 17, p. 6428, doi. 10.3390/molecules28176428

By:

Almansour, Basma S.;
Binjubair, Faizah A.;
Abdel-Aziz, Alaa A.-M.;
Al-Rashood, Sara T.

Publication type:

Article

Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 1, p. 120, doi. 10.3390/molecules28010120

By:

Alkahtani, Hamad M.;
Zen, Amer Alhaj;
Obaidullah, Ahmad J.;
Alanazi, Mohammed M.;
Almehizia, Abdulrahman A.;
Ansari, Siddique Akber;
Aleanizy, Fadilah Sfouq;
Alqahtani, Fulwah Yahya;
Aldossari, Rana M.;
Algamdi, Raghad Abdullah;
Al-Rasheed, Lamees S.;
Abdel-Hamided, Sami G.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.

Publication type:

Article

Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.

Published in:

Molecules, 2022, v. 27, n. 22, p. 7703, doi. 10.3390/molecules27227703

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
Bua, Silvia;
Nocentini, Alessio;
Alkahtani, Hamad M.;
Alsaif, Nawaf A.;
Al-Agamy, Mohamed H. M.;
Supuran, Claudiu T.

Publication type:

Article

Molecular docking, DFT and antiproliferative properties of 4‐(3,4‐dimethoxyphenyl)−3‐(4‐methoxyphenyl)−1‐phenyl‐1H‐pyrazolo[3,4‐b]pyridine as potent anticancer agent with CDK2 and PIM1 inhibition potency

Published in:

Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70009

By:

Binjubair, Faizah A.;
Almansour, Basma S.;
Ziedan, Noha I.;
Abdel‐Aziz, Alaa A.‐M.;
Al‐Rashood, Sara T.;
Elgohary, Mohamed K.;
Elkotamy, Mahmoud S.;
Abdel‐Aziz, Hatem A.

Publication type:

Article

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1487, doi. 10.1080/14756366.2021.1946044

By:

Fares, Salma;
Selim, Khalid B.;
Goda, Fatma E.;
El-Sayed, Magda A. A.;
AlSaif, Nawaf A.;
Hefnawy, Mohamed M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.

Publication type:

Article

Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1520, doi. 10.1080/14756366.2021.1924698

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
AlSaif, Nawaf A.;
Obaidullah, Ahmad J.;
Al-Obaid, Abdulrahman M.;
Al-Suwaidan, Ibrahim A.

Publication type:

Article

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 733, doi. 10.1080/14756366.2020.1742117

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Bua, Silvia;
Nocentini, Alessio;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
El-Gendy, Manal A.;
Ahmed, Hany E. A.;
Supuran, Claudiu T.

Publication type:

Article

Synthesis, antitumor activity, and molecular docking study of 2-cyclopentyloxyanisole derivatives: mechanistic study of enzyme inhibition.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 744, doi. 10.1080/14756366.2020.1740695

By:

El-Husseiny, Walaa M.;
El-Sayed, Magda A.-A.;
El-Azab, Adel S.;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 598, doi. 10.1080/14756366.2020.1722121

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ahmed, Hany E. A.;
Bua, Sivia;
Nocentini, Alessio;
AlSaif, Nawaf A.;
Obaidullah, Ahmad J.;
Hefnawy, Mohamed M.;
Supuran, Claudiu T.

Publication type:

Article

Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 610, doi. 10.1080/14756366.2020.1722120

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
El-Gendy, Manal A.;
Obaidullah, Ahmad J.;
Alkahtani, Hamad M.;
Almehizia, Abdulrahman A.;
Al-Suwaidan, Ibrahim A.

Publication type:

Article

Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 989, doi. 10.1080/14756366.2018.1474878

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Abou-Zeid, Laila A.;
El-Husseiny, Walaa M.;
El_Morsy, Ahmad M.;
El-Gendy, Manal A.;
El-Sayed, Magda A.-A.

Publication type:

Article

Synthesis, antitumour and antioxidant activities of novel α,β-unsaturated ketones and related heterocyclic analogues: EGFR inhibition and molecular modelling study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 507, doi. 10.1080/14756366.2018.1434519

By:

El-Husseiny, Walaa M.;
El-Sayed, Magda A.-A.;
Abdel-Aziz, Naglaa I.;
El-Azab, Adel S.;
Ahmed, Esam R.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 199, doi. 10.1080/14756366.2017.1407926

By:

El-Sayed, Magda A.-A.;
El-Husseiny, Walaa M.;
Abdel-Aziz, Naglaa I.;
El-Azab, Adel S.;
Abuelizz, Hatem A.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 1229, doi. 10.1080/14756366.2017.1368504

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
Al-Gendy, Manal A.

Publication type:

Article

Synthesis, anticancer and apoptosis-inducing activities of quinazoline–isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 935, doi. 10.1080/14756366.2017.1344981

By:

El-Azab, Adel S.;
Al-Dhfyan, Abdullah;
Abdel-Aziz, Alaa A.-M.;
Abou-Zeid, Laila A.;
Alkahtani, Hamad M.;
Al-Obaid, Abdulrahman M.;
Al-Gendy, Manal A.

Publication type:

Article

Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 796, doi. 10.3109/14756366.2015.1069288

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Alanazi, Amer M.;
Asiri, Yousif A.;
Al-Suwaidan, Ibrahim A.;
Maarouf, Azza R.;
Ayyad, Rezk R.;
Shawer, Taghreed Z.

Publication type:

Article

Synthesis, antitumor and antimicrobial activity of some new 6-methyl-3-phenyl-4(3 H )-quinazolinone analogues: in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 721, doi. 10.3109/14756366.2015.1060482

By:

Alanazi, Amer M.;
Abdel-Aziz, Alaa A.-M.;
Shawer, Taghreed Z.;
Ayyad, Rezk R.;
Al-Obaid, Abdulrahman M.;
Al-Agamy, Mohamed H. M.;
Maarouf, Azza R.;
El-Azab, Adel S.

Publication type:

Article

Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4(3H)quinazolinone analogues.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 1, p. 78, doi. 10.3109/14756366.2015.1004059

By:

Al-Suwaidan, Ibrahim A.;
Abdel-Aziz, Alaa A.-M.;
Shawer, Taghreed Z.;
Ayyad, Rezk R.;
Alanazi, Amer M.;
El-Morsy, Ahmad M.;
Mohamed, Menshawy A.;
Abdel-Aziz, Naglaa I.;
El-Sayed, Magda A.-A.;
El-Azab, Adel S.

Publication type:

Article

Antitumor evaluation and molecular docking study of substituted 2-benzylidenebutane-1,3-dione, 2-hydrazonobutane-1,3-dione and trifluoromethyl-1H-pyrazole analogues.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 4, p. 679, doi. 10.3109/14756366.2014.960863

By:

Al-Suwaidan, Ibrahim A.;
Abdel-Aziz, Naglaa I.;
El-Azab, Adel S.;
El-Sayed, Magda A.-A.;
Alanazi, Amer M.;
El-Ashmawy, Mahmoud B.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 1, p. 81, doi. 10.3109/14756366.2014.880696

By:

Abdel-Aziz, Alaa A-M.;
El-Azab, Adel S.;
Ekinci, Deniz;
Şentürk, Murat;
Supuran, Claudiu T.

Publication type:

Article

Antitumor Activity and Multi-Target Mechanism of Phenolic Schiff Bases Bearing Methanesulfonamide Fragments: Cell Cycle Analysis and a Molecular Modeling Study.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13621, doi. 10.3390/ijms252413621

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Brogi, Simone;
Ayyad, Rezk R.;
Al-Suwaidan, Ibrahim A.;
Hefnawy, Mohamed

Publication type:

Article

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography.

Published in:

Journal of Chemistry, 2021, p. 1, doi. 10.1155/2021/6612177

By:

El-Azab, Adel S.;
Khalil, Nasr Y.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Antibacterial evaluation of 2-(6-Chloro-2-p-tolylquinazolin-4-ylthio) acetonitrile against pathogenic bacterial isolates with special reference to biofilm formation inhibition and anti-adherence properties.

Published in:

Journal of King Saud University - Science, 2024, v. 36, n. 8, p. N.PAG, doi. 10.1016/j.jksus.2024.103316

By:

Alasmari, Sultan Z.;
Makkawi, Mohammed H.;
Ahmad, Irfan;
Hakami, Abdulrahim R.;
Almehizia, Abdulrahman A.;
El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghazwani, Mohammed

Publication type:

Article

An Efficient Synthesis of Thioesters Via TFA-Catalyzed Reaction of Carboxylic Acid and Thiols: Remarkably Facile C–S Bond Formation.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2012, v. 187, n. 9, p. 1046, doi. 10.1080/10426507.2012.664220

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Synthesis, Antitumor Activities, and Apoptosis-Inducing Activities of Schiff's Bases Incorporating Imidazolidine-2,4-dione Scaffold: Molecular Docking Studies and Enzymatic Inhibition Activities.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 4, p. 496, doi. 10.3390/ph18040496

By:

Alanazi, Fhdah S.;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Asiri, Hanadi H.;
Bakheit, Ahmed H.;
Al-Omary, Fatmah A.

Publication type:

Article

Synthesis and Conformational Analysis of Sterically Congested (4R)-(--)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations.

Published in:

Journal of Chemistry, 2014, p. 1, doi. 10.1155/2014/173902

By:

Al-Swaidan, Ibrahim A.;
El-Azab, Adel S.;
Alanazi, Amer M.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

An Alternative Route for Synthesis of Chiral 4-Substituted 1-Arenesulfonyl-2-imidazolidinones: Unusual Utility of (4S,5S)- and (4R,5R)-4,5-Dimethoxy-2-imidazolidinones and X-Ray Crystallography.

Published in:

Journal of Chemistry, 2013, p. 1, doi. 10.1155/2013/349519

By:

Al-Swaidan, Ibrahim A.;
Alanazi, Amer M.;
El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Works matching AU Abdel-Aziz, Alaa A-M.

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin.

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.

Hirshfeld Surface, Molecular Docking Study, Spectroscopic Characterization and NLO Profile of 2-Methoxy-4,6- Diphenylnicotinonitrile.

Structural, Spectroscopic, Electronic and Molecular Docking Studies on (11R,12 S)‐16‐Aminotetracyclo[6.6.2.0<sup>2,7</sup>.0<sup>9,14</sup>]hexadeca‐2(7),3,5,9(14),10,12‐hexaen‐15‐ol.

4‐[(1, 3‐Dioxoisoindolin‐2‐yl)methyl]benzenesulfonamide: Full Structural and Spectroscopic Characterization and Molecular Docking with Carbonic Anhydrase II.

Crystal, molecular structure, and conformational preferences of 3-(2-(4-morpholinophenyl)-2-oxoethyl)-5,5-diphenylimidazolidine-2,4-dione.

Crystal structure of 6-iodo-3-phenyl-2-propylquinazolin-4(3H)-one, C<sub>17</sub>H<sub>15</sub>IN<sub>2</sub>O.

Crystal structure of (E)-N′-((4-aminophenyl)sulfonyl)-N,N-dimethylformimidamide, C<sub>9</sub>H<sub>13</sub>N<sub>3</sub>O<sub>2</sub>S.

Synthesis and In Vitro Anticancer Activity of Novel 4-Aryl-3-(4-methoxyphenyl)-1-phenyl-1 H -pyrazolo[3,4- b ]pyridines Arrest Cell Cycle and Induce Cell Apoptosis by Inhibiting CDK2 and/or CDK9.

Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors.

Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.

Molecular docking, DFT and antiproliferative properties of 4‐(3,4‐dimethoxyphenyl)−3‐(4‐methoxyphenyl)−1‐phenyl‐1H‐pyrazolo[3,4‐b]pyridine as potent anticancer agent with CDK2 and PIM1 inhibition potency

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study.

Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study.

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.

Synthesis, antitumor activity, and molecular docking study of 2-cyclopentyloxyanisole derivatives: mechanistic study of enzyme inhibition.

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors.

Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study.

Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies.

Synthesis, antitumour and antioxidant activities of novel α,β-unsaturated ketones and related heterocyclic analogues: EGFR inhibition and molecular modelling study.

Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study.

Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues.

Synthesis, anticancer and apoptosis-inducing activities of quinazoline–isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies.

Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.

Synthesis, antitumor and antimicrobial activity of some new 6-methyl-3-phenyl-4(3 H )-quinazolinone analogues: in silico studies.

Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4(3H)quinazolinone analogues.

Antitumor evaluation and molecular docking study of substituted 2-benzylidenebutane-1,3-dione, 2-hydrazonobutane-1,3-dione and trifluoromethyl-1H-pyrazole analogues.

Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors.

Antitumor Activity and Multi-Target Mechanism of Phenolic Schiff Bases Bearing Methanesulfonamide Fragments: Cell Cycle Analysis and a Molecular Modeling Study.

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography.

Antibacterial evaluation of 2-(6-Chloro-2-p-tolylquinazolin-4-ylthio) acetonitrile against pathogenic bacterial isolates with special reference to biofilm formation inhibition and anti-adherence properties.

An Efficient Synthesis of Thioesters Via TFA-Catalyzed Reaction of Carboxylic Acid and Thiols: Remarkably Facile C–S Bond Formation.

Synthesis, Antitumor Activities, and Apoptosis-Inducing Activities of Schiff's Bases Incorporating Imidazolidine-2,4-dione Scaffold: Molecular Docking Studies and Enzymatic Inhibition Activities.

Synthesis and Conformational Analysis of Sterically Congested (4R)-(--)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations.

An Alternative Route for Synthesis of Chiral 4-Substituted 1-Arenesulfonyl-2-imidazolidinones: Unusual Utility of (4S,5S)- and (4R,5R)-4,5-Dimethoxy-2-imidazolidinones and X-Ray Crystallography.