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Polymodal K<sup>+</sup> channel modulation contributes to dual analgesic and anti-inflammatory actions of traditional botanical medicines.
- Published in:
- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06752-y
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- Article
A novel autism-associated KCNB1 mutation dramatically slows Kv2.1 potassium channel activation, deactivation and inactivation.
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- Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1438101
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- Article
Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice.
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- Cardiovascular Drugs & Therapy, 2024, v. 38, n. 2, p. 279, doi. 10.1007/s10557-022-07419-8
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- Article
Medicinal plant rosemary relaxes blood vessels by activating vascular smooth muscle KCNQ channels.
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- FASEB Journal, 2023, v. 37, n. 9, p. 1, doi. 10.1096/fj.202301132R
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- Article
The plant‐derived alkaloid aloperine prevents ischemia/reperfusion injury‐induced sudden cardiac death.
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- FASEB Journal, 2023, v. 37, n. 7, p. 1, doi. 10.1096/fj.202300253R
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- Article
Ancient medicinal plant rosemary contains a highly efficacious and isoform-selective KCNQ potassium channel opener.
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- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05021-8
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- Article
Behavioral and neuro-functional consequences of eliminating the KCNQ3 GABA binding site in mice.
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- Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1192628
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- Article
Native American ataxia medicines rescue ataxia-linked mutant potassium channel activity via binding to the voltage sensing domain.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38834-6
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- Article
Empagliflozin protects against renal ischemia/reperfusion injury in mice.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-24103-x
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- Article
KCNQ5 activation by tannins mediates vasorelaxant effects of barks used in Native American botanical medicine.
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- FASEB Journal, 2022, v. 36, n. 9, p. 1, doi. 10.1096/fj.202200724R
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- Article
How many SARS-CoV-2 "viroporins" are really ion channels?
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03669-2
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- Article
Case report: A novel loss-of-function pathogenic variant in the KCNA1 cytoplasmic N-terminus causing carbamazepine-responsive type 1 episodic ataxia.
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- Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.975849
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- Article
Protective effect of remote liver ischemic postconditioning on pulmonary ischemia and reperfusion injury in diabetic and non-diabetic rats.
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- PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0268571
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- Article
Activation of SGK1.1 Upregulates the M-current in the Presence of Epilepsy Mutations.
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- Frontiers in Molecular Neuroscience, 2021, v. 14, p. 1, doi. 10.3389/fnmol.2021.798261
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- Article
KCNQ and KCNE Isoform-Dependent Pharmacology Rationalizes Native American Dual Use of Specific Plants as Both Analgesics and Gastrointestinal Therapeutics.
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- Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.777057
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- Article
Empagliflozin protects the heart against ischemia/reperfusion-induced sudden cardiac death.
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- Cardiovascular Diabetology, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12933-021-01392-6
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- Article
Intergenerational trauma transmission is associated with brain metabotranscriptome remodeling and mitochondrial dysfunction.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02255-2
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- Article
The envelope protein of SARS‐CoV‐2 increases intra‐Golgi pH and forms a cation channel that is regulated by pH.
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- Journal of Physiology, 2021, v. 599, n. 11, p. 2851, doi. 10.1113/JP281037
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- Article
Fluorescence Fluctuation Spectroscopy enables quantification of potassium channel subunit dynamics and stoichiometry.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90002-2
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- Article
KCNQ5 Potassium Channel Activation Underlies Vasodilation by Tea.
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- Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2021, v. 55, p. 46, doi. 10.33594/00000033
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- Article
The Amyloid Precursor Protein C99 Fragment Modulates Voltage-Gated Potassium Channels.
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- Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2021, v. 55, p. 157, doi. 10.33594/000000397
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- Article
Hypochlorhydria reduces mortality in heart failure caused by Kcne2 gene deletion.
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- FASEB Journal, 2020, v. 34, n. 8, p. 10699, doi. 10.1096/fj.202000013RR
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- Article
Metabolomic and transcriptomic signatures of prenatal excessive methionine support nature rather than nurture in schizophrenia pathogenesis.
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- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01124-8
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- Article
The ubiquitous flavonoid quercetin is an atypical KCNQ potassium channel activator.
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- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-1089-8
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- Article
KCNQs: Ligand- and Voltage-Gated Potassium Channels.
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- Frontiers in Physiology, 2020, v. 11, p. 1, doi. 10.3389/fphys.2020.00583
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- Article
Potassium channels act as chemosensors for solute transporters.
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- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0820-9
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- Article
In silico re-engineering of a neurotransmitter to activate KCNQ potassium channels in an isoform-specific manner.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0648-3
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- Article
Cilantro leaf harbors a potent potassium channel-activating anticonvulsant.
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- FASEB Journal, 2019, v. 33, n. 10, p. 1, doi. 10.1096/fj.201900485R
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- Article
The KCNE2 potassium channel β subunit is required for normal lung function and resilience to ischemia and reperfusion injury.
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- FASEB Journal, 2019, v. 33, n. 9, p. 9762, doi. 10.1096/fj.201802519R
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- Article
KCNQ1 rescues TMC1 plasma membrane expression but not mechanosensitive channel activity.
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- Journal of Cellular Physiology, 2019, v. 234, n. 8, p. 13361, doi. 10.1002/jcp.28013
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- Article
Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular K<sub>V</sub> currents and predisposes to ventricular arrhythmia.
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- FASEB Journal, 2019, v. 33, n. 2, p. 2537, doi. 10.1096/fj.201800502R
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- Article
AKT and ERK1/2 activation via remote ischemic preconditioning prevents Kcne2‐dependent sudden cardiac death.
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- Physiological Reports, 2019, v. 7, n. 3, p. N.PAG, doi. 10.14814/phy2.13957
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- Article
Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06339-2
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- Article
Remote ischemic preconditioning STAT3-dependently ameliorates pulmonary ischemia/reperfusion injury.
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- PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0196186
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- Article
Direct neurotransmitter activation of voltage-gated potassium channels.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04266-w
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- Article
Chansporter complexes in cell signaling.
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- FEBS Letters, 2017, v. 591, n. 17, p. 2556, doi. 10.1002/1873-3468.12755
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- Article
β Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation.
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- Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00646
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- Article
KCNQ-SMIT complex formation facilitates ion channel-solute transporter cross talk.
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- FASEB Journal, 2017, v. 31, n. 7, p. 2828, doi. 10.1096/fj.201601334R
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- Article
Targeted deletion of Kcne3 impairs skeletal muscle function in mice.
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- FASEB Journal, 2017, v. 31, n. 7, p. 2937, doi. 10.1096/fj.201600965RR
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- Article
Kcne2 deletion impairs insulin secretion and causes type 2 diabetes mellitus.
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- FASEB Journal, 2017, v. 31, n. 6, p. 2674, doi. 10.1096/fj.201601347
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- Article
β Subunits Functionally Differentiate Human Kv4.3 Potassium Channel Splice Variants.
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- Frontiers in Physiology, 2017, v. 8, p. 1, doi. 10.3389/fphys.2017.00066
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- Article
Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4.
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- Scientific Reports, 2016, p. 38412, doi. 10.1038/srep38412
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- Article
Kcne4 Deletion Sex-Dependently Alters Vascular Reactivity.
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- Journal of Vascular Research, 2016, v. 53, n. 3-4, p. 138, doi. 10.1159/000449060
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- Article
Channel-transporter complexes: an emerging theme in cell signaling.
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- 2016
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- Publication type:
- Opinion
Remote Liver Ischemic Preconditioning Protects against Sudden Cardiac Death via an ERK/GSK-3β-Dependent Mechanism.
- Published in:
- PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165123
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- Article
Novel exon 1 protein‐coding regions N‐terminally extend human KCNE3 and KCNE4.
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- FASEB Journal, 2016, v. 30, n. 8, p. 2959, doi. 10.1096/fj.201600467R
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- Article
Kcne2 deletion attenuates acute post-ischaemia/ reperfusion myocardial infarction.
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- Cardiovascular Research, 2016, v. 110, n. 2, p. 227, doi. 10.1093/cvr/cvw048
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- Article
Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia.
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- Scientific Reports, 2016, p. 23118, doi. 10.1038/srep23118
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- Article
Kcne4 deletion sex- and age-specifically impairs cardiac repolarization in mice.
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- FASEB Journal, 2016, v. 30, n. 1, p. 360, doi. 10.1096/fj.15-278754
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- Article
Ion Channels under the Sun.
- Published in:
- FASEB Journal, 2014, v. 28, n. 5, p. 1957, doi. 10.1096/fj.14-0501ufm
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- Article