Works by Łażewska, Dorota

Results: 39

Selenium-Containing Agents Acting on Cancer—A New Hope?

Published in:

Pharmaceutics, 2023, v. 15, n. 1, p. 104, doi. 10.3390/pharmaceutics15010104

By:

Garbo, Sabrina;
Di Giacomo, Silvia;
Łażewska, Dorota;
Honkisz-Orzechowska, Ewelina;
Di Sotto, Antonella;
Fioravanti, Rossella;
Zwergel, Clemens;
Battistelli, Cecilia

Publication type:

Article

Dual Targeting Ligands—Histamine H 3 Receptor Ligands with Monoamine Oxidase B Inhibitory Activity—In Vitro and In Vivo Evaluation.

Published in:

Pharmaceutics, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/pharmaceutics14102187

By:

Łażewska, Dorota;
Siwek, Agata;
Olejarz-Maciej, Agnieszka;
Doroz-Płonka, Agata;
Wiktorowska-Owczarek, Anna;
Jóźwiak-Bębenista, Marta;
Reiner-Link, David;
Frank, Annika;
Sromek-Trzaskowska, Wioletta;
Honkisz-Orzechowska, Ewelina;
Królicka, Ewelina;
Stark, Holger;
Wieczorek, Marek;
Wagner, Waldemar;
Kieć-Kononowicz, Katarzyna;
Stasiak, Anna

Publication type:

Article

Alleviation of Autophagic Deficits and Neuroinflammation by Histamine H3 Receptor Antagonist E159 Ameliorates Autism-Related Behaviors in BTBR Mice.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 10, p. 1293, doi. 10.3390/ph17101293

By:

Thomas, Shilu Deepa;
Jayaprakash, Petrilla;
Marwan, Nurfirzana Z. H. J.;
Aziz, Ezzatul A. B. A.;
Kuder, Kamil;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

Effects of the DL76 Antagonist/Inverse Agonist of Histamine H 3 Receptors on Experimental Periodontitis in Rats: Morphological Studies.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 6, p. 792, doi. 10.3390/ph17060792

By:

Geremek, Mariusz;
Drozdzowska, Bogna;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Jochem, Jerzy

Publication type:

Article

Efficacy of the Multi-Target Compound E153 in Relieving Pain and Pruritus of Different Origins.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 10, p. 1481, doi. 10.3390/ph16101481

By:

Mogilski, Szczepan;
Kubacka, Monika;
Świerczek, Artur;
Wyska, Elżbieta;
Szczepańska, Katarzyna;
Sapa, Jacek;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota

Publication type:

Article

Chalcones as Potential Ligands for the Treatment of Parkinson's Disease.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 7, p. N.PAG, doi. 10.3390/ph15070847

By:

Królicka, Ewelina;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota

Publication type:

Article

Histamine H3 receptor antagonists/inverse agonists: a patent review (October 2017 – December 2023) documenting progress.

Published in:

Expert Opinion on Therapeutic Patents, 2025, v. 35, n. 3, p. 251, doi. 10.1080/13543776.2024.2446227

By:

Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Progress in the development of histamine H 3 receptor antagonists/inverse agonists: a patent review (2013-2017).

Published in:

Expert Opinion on Therapeutic Patents, 2018, v. 28, n. 3, p. 175, doi. 10.1080/13543776.2018.1424135

By:

Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

New developments around histamine H3 receptor antagonists/inverse agonists: a patent review (2010 - present).

Published in:

Expert Opinion on Therapeutic Patents, 2014, v. 24, n. 1, p. 89, doi. 10.1517/13543776.2014.848197

By:

Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

The Search for Histamine H4 Receptor Ligands with Anticancer Activity among Novel (Thio)urea Derivatives.

Published in:

ChemistrySelect, 2019, v. 4, n. 36, p. 10943, doi. 10.1002/slct.201902747

By:

Domínguez‐Álvarez, Enrique;
Łażewska, Dorota;
Szabó, Zsanett;
Hagenow, Stefanie;
Reiner, David;
Gajdács, Márió;
Spengler, Gabriella;
Stark, Holger;
Handzlik, Jadwiga;
Kieć‐Kononowicz, Katarzyna

Publication type:

Article

AR71, Histamine H 3 Receptor Ligand—In Vitro and In Vivo Evaluation (Anti-Inflammatory Activity, Metabolic Stability, Toxicity, and Analgesic Action).

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 15, p. 8035, doi. 10.3390/ijms25158035

By:

Stasiak, Anna;
Honkisz-Orzechowska, Ewelina;
Gajda, Zbigniew;
Wagner, Waldemar;
Popiołek-Barczyk, Katarzyna;
Kuder, Kamil J.;
Latacz, Gniewomir;
Juszczak, Michał;
Woźniak, Katarzyna;
Karcz, Tadeusz;
Szczepańska, Katarzyna;
Jóźwiak-Bębenista, Marta;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota

Publication type:

Article

Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A 2A and Dual A 1 /A 2A Receptor Affinity.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13707, doi. 10.3390/ijms241813707

By:

Załuski, Michał;
Łażewska, Dorota;
Jaśko, Piotr;
Honkisz-Orzechowska, Ewelina;
Kuder, Kamil J.;
Brockmann, Andreas;
Latacz, Gniewomir;
Zygmunt, Małgorzata;
Kaleta, Maria;
Greser, Beril Anita;
Olejarz-Maciej, Agnieszka;
Jastrzębska-Więsek, Magdalena;
Vielmuth, Christin;
Müller, Christa E.;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced Amnesia in Mice.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12719, doi. 10.3390/ijms241612719

By:

Abdalla, Sabna;
Eissa, Nermin;
Jayaprakash, Petrilla;
Beiram, Rami;
Kuder, Kamil J.;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3996, doi. 10.3390/ijms21113996

By:

Eissa, Nermin;
Azimullah, Sheikh;
Jayaprakash, Petrilla;
Jayaraj, Richard L.;
Reiner, David;
Ojha, Shreesh K.;
Beiram, Rami;
Stark, Holger;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 10, p. 3411, doi. 10.3390/ijms21103411

By:

Łażewska, Dorota;
Olejarz-Maciej, Agnieszka;
Reiner, David;
Kaleta, Maria;
Latacz, Gniewomir;
Zygmunt, Małgorzata;
Doroz-Płonka, Agata;
Karcz, Tadeusz;
Frank, Annika;
Stark, Holger;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Role of Histamine H3 Receptor Antagonists on Intraocular Pressure Reduction in Rabbit Models of Transient Ocular Hypertension and Glaucoma.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 4, p. 981, doi. 10.3390/ijms20040981

By:

Lanzi, Cecilia;
Lucarini, Laura;
Durante, Mariaconcetta;
Sgambellone, Silvia;
Pini, Alessandro;
Catarinicchia, Stefano;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Stark, Holger;
Masini, Emanuela

Publication type:

Article

Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3386, doi. 10.3390/ijms19113386

By:

Alachkar, Alaa;
Łażewska, Dorota;
Latacz, Gniewomir;
Frank, Annika;
Siwek, Agata;
Lubelska, Annamaria;
Honkisz-Orzechowska, Ewelina;
Handzlik, Jadwiga;
Stark, Holger;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

Antinociceptive effects of novel histamine H3 and H4 receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse.

Published in:

2018

By:

Popiolek‐Barczyk, Katarzyna;
Łażewska, Dorota;
Latacz, Gniewomir;
Olejarz, Agnieszka;
Makuch, Wioletta;
Stark, Holger;
Kieć‐Kononowicz, Katarzyna;
Mika, Joanna;
Popiolek-Barczyk, Katarzyna;
Kieć-Kononowicz, Katarzyna

Publication type:

journal article

Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats

Published in:

Neuropsychiatric Disease & Treatment, 2019, v. 15, p. 531, doi. 10.2147/NDT.S193125

By:

Alachkar, Alaa;
Khan, Nadia;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31385-7

By:

Eissa, Nermin;
Jayaprakash, Petrilla;
Azimullah, Sheikh;
Ojha, Shreesh K.;
Al-Houqani, Mohammed;
Jalal, Fakhreya Y.;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 9, p. 1251, doi. 10.3390/biom10091251

By:

Eissa, Nermin;
Jayaprakash, Petrilla;
Stark, Holger;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

The lipophilicity estimation of 5-arylidene derivatives of (2-thio)hydantoin with antimycobacterial activity.

Published in:

Biomedical Chromatography, 2007, v. 21, n. 3, p. 291, doi. 10.1002/bmc.755

By:

Łażewska, Dorota;
Maludziński, Piotr;
Szymańska, Ewa;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Anti-inflammatory effects of new human histamine H3 receptor ligands with flavonoid structure on BV-2 neuroinflammation.

Published in:

Inflammation Research, 2023, v. 72, n. 2, p. 181, doi. 10.1007/s00011-022-01658-z

By:

Honkisz-Orzechowska, Ewelina;
Popiołek-Barczyk, Katarzyna;
Linart, Zuzanna;
Filipek-Gorzała, Jadwiga;
Rudnicka, Anna;
Siwek, Agata;
Werner, Tobias;
Stark, Holger;
Chwastek, Jakub;
Starowicz, Katarzyna;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota

Publication type:

Article

Aryl-1,3,5-triazine ligands of histamine H receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide.

Published in:

Inflammation Research, 2017, v. 66, n. 1, p. 79, doi. 10.1007/s00011-016-0997-z

By:

Mogilski, Szczepan;
Kubacka, Monika;
Łażewska, Dorota;
Więcek, Małgorzata;
Głuch-Lutwin, Monika;
Tyszka-Czochara, Małgorzata;
Bukowska-Strakova, Karolina;
Filipek, Barbara;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Reproductive and fetal toxicity studies of histamine H3 receptor antagonist DL76 used in mice to prevent maximal electroshock-induced seizure.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1364353

By:

Bastaki, Salim M.;
Abdulrazzaq, Yousef M.;
Zidan, Marwan Abdelrahim;
Shafiullah, Mohamed;
Alaryani, Saif Ghdayer;
Alnuaimi, Fatima Awad;
Adeghate, Ernest;
Mohsin, Sahar;
Akour, Amal;
Siwek, Agata;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem

Publication type:

Article

Cunninghamella as a Microbiological Model for Metabolism of Histamine H Receptor Antagonist 1-[3-(4- tert-Butylphenoxy)propyl]piperidine.

Published in:

Applied Biochemistry & Biotechnology, 2012, v. 168, n. 6, p. 1584, doi. 10.1007/s12010-012-9880-8

By:

Pękala, Elżbieta;
Kubowicz, Paulina;
Łażewska, Dorota

Publication type:

Article

Convenient way of synthesis and crystal structure of 1-[(5-chloro-1 H-indol-2-yl)carbonyl]-4-methylpiperazine, a histamine H4 receptor antagonist.

Published in:

Heterocyclic Communications, 2011, v. 17, n. 5/6, p. 207, doi. 10.1515/HC.2011.035

By:

Łażewska, Dorota;
Karolak-Wojciechowska, Janina;
Kolesińska, Beata;
Kamiński, Zbigniew;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Dual-Acting Diether Derivatives of Piperidine and Homopiperidine with Histamine H3 Receptor Antagonistic and Anticholinesterase Activity.

Published in:

Archiv der Pharmazie, 2012, v. 345, n. 8, p. 591, doi. 10.1002/ardp.201200018

By:

Bajda, Marek;
Kuder, Kamil J.;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Więckowska, Anna;
Ignasik, Michalina;
Guzior, Natalia;
Jończyk, Jakub;
Malawska, Barbara

Publication type:

Article

Uncovering the Power of GPR18 Signalling: How RvD2 and Other Ligands Could Have the Potential to Modulate and Resolve Inflammation in Various Health Disorders.

Published in:

Molecules, 2024, v. 29, n. 6, p. 1258, doi. 10.3390/molecules29061258

By:

Honkisz-Orzechowska, Ewelina;
Łażewska, Dorota;
Baran, Grzegorz;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Trisubstituted 1,3,5-Triazines as Histamine H 4 Receptor Antagonists with Promising Activity In Vivo.

Published in:

Molecules, 2023, v. 28, n. 10, p. 4199, doi. 10.3390/molecules28104199

By:

Olejarz-Maciej, Agnieszka;
Mogilski, Szczepan;
Karcz, Tadeusz;
Werner, Tobias;
Kamińska, Katarzyna;
Kupczyk, Jarosław;
Honkisz-Orzechowska, Ewelina;
Latacz, Gniewomir;
Stark, Holger;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota

Publication type:

Article

Multitargeting Histamine H 3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives.

Published in:

Molecules, 2023, v. 28, n. 5, p. 2349, doi. 10.3390/molecules28052349

By:

Łażewska, Dorota;
Kaleta, Maria;
Zaręba, Paula;
Godyń, Justyna;
Dubiel, Mariam;
Honkisz-Orzechowska, Ewelina;
Doroz-Płonka, Agata;
Więckowska, Anna;
Stark, Holger;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

New Triazine Derivatives as Serotonin 5-HT 6 Receptor Ligands.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1108, doi. 10.3390/molecules28031108

By:

Łażewska, Dorota;
Więcek, Małgorzata;
Satała, Grzegorz;
Chałupnik, Paulina;
Żesławska, Ewa;
Honkisz-Orzechowska, Ewelina;
Tarasek, Monika;
Latacz, Gniewomir;
Nitek, Wojciech;
Szymańska, Ewa;
Handzlik, Jadwiga

Publication type:

Article

Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.

Published in:

Molecules, 2023, v. 28, n. 1, p. 238, doi. 10.3390/molecules28010238

By:

Godyń, Justyna;
Zaręba, Paula;
Stary, Dorota;
Kaleta, Maria;
Kuder, Kamil J.;
Latacz, Gniewomir;
Mogilski, Szczepan;
Reiner-Link, David;
Frank, Annika;
Doroz-Płonka, Agata;
Olejarz-Maciej, Agnieszka;
Sudoł-Tałaj, Sylwia;
Nolte, Tobias;
Handzlik, Jadwiga;
Stark, Holger;
Więckowska, Anna;
Malawska, Barbara;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota;
Bajda, Marek

Publication type:

Article

Biphenylalkoxyamine Derivatives–Histamine H 3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.

Published in:

Molecules, 2021, v. 26, n. 12, p. 3580, doi. 10.3390/molecules26123580

By:

Łażewska, Dorota;
Zaręba, Paula;
Godyń, Justyna;
Doroz-Płonka, Agata;
Frank, Annika;
Reiner-Link, David;
Bajda, Marek;
Stary, Dorota;
Mogilski, Szczepan;
Olejarz-Maciej, Agnieszka;
Kaleta, Maria;
Stark, Holger;
Malawska, Barbara;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1575, doi. 10.3390/molecules25071575

By:

Alachkar, Alaa;
Azimullah, Sheikh;
Lotfy, Mohamed;
Adeghate, Ernest;
Ojha, Shreesh K.;
Beiram, Rami;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem;
Plech, Tomasz

Publication type:

Article

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4472, doi. 10.3390/molecules24244472

By:

Lubelska, Annamaria;
Latacz, Gniewomir;
Jastrzębska-Więsek, Magdalena;
Kotańska, Magdalena;
Kurczab, Rafał;
Partyka, Anna;
Marć, Małgorzata Anna;
Wilczyńska, Daria;
Doroz-Płonka, Agata;
Łażewska, Dorota;
Wesołowska, Anna;
Kieć-Kononowicz, Katarzyna;
Handzlik, Jadwiga;
Sánchez-Murcia, Pedro A.;
Gigante, Alba;
Pérez, Víctor Sebastián

Publication type:

Article

The Neuroprotective Effects of Histamine H3 Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in Rats.

Published in:

Molecules, 2019, v. 24, n. 22, p. 4106, doi. 10.3390/molecules24224106

By:

Alachkar, Alaa;
Azimullah, Sheikh;
Ojha, Shreesh K.;
Beiram, Rami;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Sadek, Bassem;
Bak, Istvan;
Kiss, Attila;
Lekli, Istvan

Publication type:

Article

Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT6 Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.

Published in:

Molecules, 2018, v. 23, n. 10, p. 2529, doi. 10.3390/molecules23102529

By:

Kurczab, Rafał;
Ali, Wesam;
Łażewska, Dorota;
Kotańska, Magdalena;
Jastrzębska-Więsek, Magdalena;
Satała, Grzegorz;
Więcek, Małgorzata;
Lubelska, Annamaria;
Latacz, Gniewomir;
Partyka, Anna;
Starek, Małgorzata;
Dąbrowska, Monika;
Wesołowska, Anna;
Jacob, Claus;
Kieć-Kononowicz, Katarzyna;
Handzlik, Jadwiga

Publication type:

Article

The Synthesis of 1,3,5-triazine Derivatives and JNJ7777120 Analogues with Histamine H4 Receptor Affinity and Their Interaction with PTEN Promoter.

Published in:

Chemical Biology & Drug Design, 2016, v. 88, n. 2, p. 254, doi. 10.1111/cbdd.12752

By:

Latacz, Gniewomir;
Kechagioglou, Petros;
Papi, Rigini;
Łażewska, Dorota;
Więcek, Małgorzata;
Kamińska, Katarzyna;
Wencel, Przemysław;
Karcz, Tadeusz;
Schwed, Johannes S.;
Stark, Holger;
Kyriakidis, Dimitrios A.;
Kieć ‐ Kononowicz, Katarzyna

Publication type:

Article

Works by Łażewska, Dorota

Selenium-Containing Agents Acting on Cancer—A New Hope?

Dual Targeting Ligands—Histamine H 3 Receptor Ligands with Monoamine Oxidase B Inhibitory Activity—In Vitro and In Vivo Evaluation.

Alleviation of Autophagic Deficits and Neuroinflammation by Histamine H3 Receptor Antagonist E159 Ameliorates Autism-Related Behaviors in BTBR Mice.

Effects of the DL76 Antagonist/Inverse Agonist of Histamine H 3 Receptors on Experimental Periodontitis in Rats: Morphological Studies.

Efficacy of the Multi-Target Compound E153 in Relieving Pain and Pruritus of Different Origins.

Chalcones as Potential Ligands for the Treatment of Parkinson's Disease.

Histamine H<sub>3</sub> receptor antagonists/inverse agonists: a patent review (October 2017 – December 2023) documenting progress.

Progress in the development of histamine H 3 receptor antagonists/inverse agonists: a patent review (2013-2017).

New developments around histamine H<sub>3</sub> receptor antagonists/inverse agonists: a patent review (2010 - present).

The Search for Histamine H<sub>4</sub> Receptor Ligands with Anticancer Activity among Novel (Thio)urea Derivatives.

AR71, Histamine H 3 Receptor Ligand—In Vitro and In Vivo Evaluation (Anti-Inflammatory Activity, Metabolic Stability, Toxicity, and Analgesic Action).

Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A 2A and Dual A 1 /A 2A Receptor Affinity.

The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced Amnesia in Mice.

The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice.

Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors.

Role of Histamine H3 Receptor Antagonists on Intraocular Pressure Reduction in Rabbit Models of Transient Ocular Hypertension and Glaucoma.

Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats.

Antinociceptive effects of novel histamine H<sub>3</sub> and H<sub>4</sub> receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse.

Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats

The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.

Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism.

The lipophilicity estimation of 5-arylidene derivatives of (2-thio)hydantoin with antimycobacterial activity.

Anti-inflammatory effects of new human histamine H<sub>3</sub> receptor ligands with flavonoid structure on BV-2 neuroinflammation.

Aryl-1,3,5-triazine ligands of histamine H receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide.

Reproductive and fetal toxicity studies of histamine H3 receptor antagonist DL76 used in mice to prevent maximal electroshock-induced seizure.

Cunninghamella as a Microbiological Model for Metabolism of Histamine H Receptor Antagonist 1-[3-(4- tert-Butylphenoxy)propyl]piperidine.

Convenient way of synthesis and crystal structure of 1-[(5-chloro-1 H-indol-2-yl)carbonyl]-4-methylpiperazine, a histamine H<sub>4</sub> receptor antagonist.

Dual-Acting Diether Derivatives of Piperidine and Homopiperidine with Histamine H<sub>3</sub> Receptor Antagonistic and Anticholinesterase Activity.

Uncovering the Power of GPR18 Signalling: How RvD2 and Other Ligands Could Have the Potential to Modulate and Resolve Inflammation in Various Health Disorders.

Trisubstituted 1,3,5-Triazines as Histamine H 4 Receptor Antagonists with Promising Activity In Vivo.

Multitargeting Histamine H 3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives.

New Triazine Derivatives as Serotonin 5-HT 6 Receptor Ligands.

Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.

Biphenylalkoxyamine Derivatives–Histamine H 3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats.

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.

The Neuroprotective Effects of Histamine H3 Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in Rats.

Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT6 Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.

The Synthesis of 1,3,5-triazine Derivatives and JNJ7777120 Analogues with Histamine H<sub>4</sub> Receptor Affinity and Their Interaction with PTEN Promoter.