Found: 29

Select item for more details and to access through your institution.

  • Two coffins and a funeral: early or late caspase activation determines two types of apoptosis induced by DNA damaging agents.

    Published in:
    Apoptosis, 2017, v. 22, n. 3, p. 421, doi. 10.1007/s10495-016-1337-z
    By:
    • Oropesa-Ávila, Manuel;
    • Cruz-Ojeda, Patricia;
    • Porcuna, Jesús;
    • Villanueva-Paz, Marina;
    • Fernández-Vega, Alejandro;
    • Mata, Mario;
    • Lavera, Isabel;
    • Rivero, Juan;
    • Luzón-Hidalgo, Raquel;
    • Álvarez-Córdoba, Mónica;
    • Cotán, David;
    • Zaderenko, Ana;
    • Cordero, Mario;
    • Sánchez-Alcázar, José
    Publication type:
    Article

  • Neurodegeneration, Mitochondria, and Antibiotics.

    Published in:
    Metabolites (2218-1989), 2023, v. 13, n. 3, p. 416, doi. 10.3390/metabo13030416
    By:
    • Suárez-Rivero, Juan M.;
    • López-Pérez, Juan;
    • Muela-Zarzuela, Inés;
    • Pastor-Maldonado, Carmen;
    • Cilleros-Holgado, Paula;
    • Gómez-Fernández, David;
    • Álvarez-Córdoba, Mónica;
    • Munuera-Cabeza, Manuel;
    • Talaverón-Rey, Marta;
    • Povea-Cabello, Suleva;
    • Suárez-Carrillo, Alejandra;
    • Piñero-Pérez, Rocío;
    • Reche-López, Diana;
    • Romero-Domínguez, José M.;
    • Sánchez-Alcázar, José Antonio
    Publication type:
    Article

  • Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives.

    Published in:
    2021
    By:
    • Álvarez-Córdoba, Mónica;
    • Talaverón-Rey, Marta;
    • Villalón-García, Irene;
    • Povea-Cabello, Suleva;
    • Suárez-Rivero, Juan M.;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Salas, Joaquín J.;
    • Sánchez-Alcázar, José A.
    Publication type:
    journal article

  • Polydatin and Nicotinamide Rescue the Cellular Phenotype of Mitochondrial Diseases by Mitochondrial Unfolded Protein Response (mtUPR) Activation.

    Published in:
    Biomolecules (2218-273X), 2024, v. 14, n. 5, p. 598, doi. 10.3390/biom14050598
    By:
    • Cilleros-Holgado, Paula;
    • Gómez-Fernández, David;
    • Piñero-Pérez, Rocío;
    • Romero Domínguez, José Manuel;
    • Talaverón-Rey, Marta;
    • Reche-López, Diana;
    • Suárez-Rivero, Juan Miguel;
    • Álvarez-Córdoba, Mónica;
    • Romero-González, Ana;
    • López-Cabrera, Alejandra;
    • Oliveira, Marta Castro De;
    • Rodríguez-Sacristan, Andrés;
    • Sánchez-Alcázar, José Antonio
    Publication type:
    Article

  • Mitochondrial Quality Control via Mitochondrial Unfolded Protein Response (mtUPR) in Ageing and Neurodegenerative Diseases.

    Published in:
    Biomolecules (2218-273X), 2023, v. 13, n. 12, p. 1789, doi. 10.3390/biom13121789
    By:
    • Cilleros-Holgado, Paula;
    • Gómez-Fernández, David;
    • Piñero-Pérez, Rocío;
    • Romero-Domínguez, Jose Manuel;
    • Reche-López, Diana;
    • López-Cabrera, Alejandra;
    • Álvarez-Córdoba, Mónica;
    • Munuera-Cabeza, Manuel;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Romero-González, Ana;
    • Sánchez-Alcázar, Jose Antonio
    Publication type:
    Article

  • Mitochondria and Antibiotics: For Good or for Evil?

    Published in:
    Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 1050, doi. 10.3390/biom11071050
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?

    Published in:
    Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071611
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Reche-López, Diana;
    • Cilleros-Holgado, Paula;
    • Piñero-Pérez, Rocío;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • From Mitochondria to Atherosclerosis: The Inflammation Path.

    Published in:
    Biomedicines, 2021, v. 9, n. 3, p. 258, doi. 10.3390/biomedicines9030258
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Sánchez-Alcázar, José A.;
    • Orekhov, Alexander N.
    Publication type:
    Article

  • Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases.

    Published in:
    Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.862085
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • Romero-González, Ana;
    • Gómez-Fernandez, David;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Emerging Roles of Apoptotic Microtubules During the Execution Phase of Apoptosis.

    Published in:
    Cytoskeleton, 2015, v. 72, n. 9, p. 435, doi. 10.1002/cm.21254
    By:
    • Oropesa Ávila, Manuel;
    • Fernández Vega, Alejandro;
    • Garrido Maraver, Juan;
    • Villanueva Paz, Marina;
    • De Lavera, Isabel;
    • De La Mata, Mario;
    • Cordero, Mario D.;
    • Alcocer Gómez, Elizabet;
    • Delgado Pavón, Ana;
    • Álvarez Córdoba, Mónica;
    • Cotán, David;
    • Sánchez‐Alcázar, José Antonio
    Publication type:
    Article

  • Pantothenate and L-Carnitine Supplementation Improves Pathological Alterations in Cellular Models of KAT6A Syndrome.

    Published in:
    Genes, 2022, v. 13, n. 12, p. 2300, doi. 10.3390/genes13122300
    By:
    • Munuera-Cabeza, Manuel;
    • Álvarez-Córdoba, Mónica;
    • Suárez-Rivero, Juan M.;
    • Povea-Cabello, Suleva;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Reche-López, Diana;
    • Cilleros-Holgado, Paula;
    • Piñero-Pérez, Rocío;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Precision Medicine in Rare Diseases.

    Published in:
    Diseases, 2020, v. 8, n. 4, p. 42, doi. 10.3390/diseases8040042
    By:
    • Villalón-García, Irene;
    • Álvarez-Córdoba, Mónica;
    • Suárez-Rivero, Juan Miguel;
    • Povea-Cabello, Suleva;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Sánchez-Alcázar, José Antonio
    Publication type:
    Article

  • Mitochondrial Dynamics in Mitochondrial Diseases.

    Published in:
    Diseases, 2017, v. 5, n. 1, p. 1, doi. 10.3390/diseases5010001
    By:
    • Suárez-Rivero, Juan M.;
    • Villanueva-Paz, Marina;
    • de la Cruz-Ojeda, Patricia;
    • de la Mata, Mario;
    • Cotán, David;
    • Oropesa-Ávila, Manuel;
    • de Lavera, Isabel;
    • Álvarez-Córdoba, Mónica;
    • Luzón-Hidalgo, Raquel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • A Multi-Target Pharmacological Correction of a Lipoyltransferase LIPT1 Gene Mutation in Patient-Derived Cellular Models.

    Published in:
    Antioxidants, 2024, v. 13, n. 8, p. 1023, doi. 10.3390/antiox13081023
    By:
    • Gómez-Fernández, David;
    • Romero-González, Ana;
    • Suárez-Rivero, Juan M.;
    • Cilleros-Holgado, Paula;
    • Álvarez-Córdoba, Mónica;
    • Piñero-Pérez, Rocío;
    • Romero-Domínguez, José Manuel;
    • Reche-López, Diana;
    • López-Cabrera, Alejandra;
    • Ibáñez-Mico, Salvador;
    • Castro de Oliveira, Marta;
    • Rodríguez-Sacristán, Andrés;
    • González-Granero, Susana;
    • García-Verdugo, José Manuel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies.

    Published in:
    Antioxidants, 2023, v. 12, n. 12, p. 2023, doi. 10.3390/antiox12122023
    By:
    • Piñero-Pérez, Rocío;
    • López-Cabrera, Alejandra;
    • Álvarez-Córdoba, Mónica;
    • Cilleros-Holgado, Paula;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Gómez-Fernández, David;
    • Reche-López, Diana;
    • Romero-González, Ana;
    • Romero-Domínguez, José Manuel;
    • de Pablos, Rocío M.;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels.

    Published in:
    Orphanet Journal of Rare Diseases, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13023-023-02687-5
    By:
    • Talaverón-Rey, Marta;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Povea-Cabello, Suleva;
    • Suárez-Rivero, Juan M.;
    • Gómez-Fernández, David;
    • Romero-González, Ana;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Cilleros-Holgado, Paula;
    • Reche-López, Diana;
    • Piñero-Pérez, Rocío;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Therapeutic approach with commercial supplements for pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels.

    Published in:
    2022
    By:
    • Álvarez-Córdoba, Mónica;
    • Reche-López, Diana;
    • Cilleros-Holgado, Paula;
    • Talaverón-Rey, Marta;
    • Villalón-García, Irene;
    • Povea-Cabello, Suleva;
    • Suárez-Rivero, Juan M.;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Piñero-Pérez, Rocío;
    • Sánchez-Alcázar, José A.
    Publication type:
    journal article

  • UPR<sup>mt</sup> activation improves pathological alterations in cellular models of mitochondrial diseases.

    Published in:
    2022
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Reche-López, Diana;
    • Cilleros-Holgado, Paula;
    • Piñero-Perez, Rocío;
    • Sánchez-Alcázar, José A.
    Publication type:
    journal article

  • Coenzyme Q 10 Analogues: Benefits and Challenges for Therapeutics.

    Published in:
    Antioxidants, 2021, v. 10, n. 2, p. 236, doi. 10.3390/antiox10020236
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Munuera-Cabeza, Manuel;
    • Suárez-Carrillo, Alejandra;
    • Talaverón-Rey, Marta;
    • Sánchez-Alcázar, José A.;
    • Motterlini, Roberto
    Publication type:
    Article

  • Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration.

    Published in:
    Neural Regeneration Research, 2023, v. 18, n. 6, p. 1196, doi. 10.4103/1673-5374.358614
    By:
    • Villalón-García, Irene;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Talaverón-Rey, Marta;
    • Suárez-Rivero, Juan M.;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Reche-López, Diana;
    • Cilleros-Holgado, Paula;
    • Piñero-Pérez, Rocío;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients' Brain in a Dish.

    Published in:
    Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.610764
    By:
    • Povea-Cabello, Suleva;
    • Villanueva-Paz, Marina;
    • Suárez-Rivero, Juan M.;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Talaverón-Rey, Marta;
    • Suárez-Carrillo, Alejandra;
    • Munuera-Cabeza, Manuel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Coenzyme Q<sub>10</sub> partially restores pathological alterations in a macrophage model of Gaucher disease.

    Published in:
    2017
    By:
    • de la Mata, Mario;
    • Cotán, David;
    • Oropesa-Ávila, Manuel;
    • Villanueva-Paz, Marina;
    • de Lavera, Isabel;
    • Álvarez-Córdoba, Mónica;
    • Luzón-Hidalgo, Raquel;
    • Suárez-Rivero, Juan M.;
    • Tiscornia, Gustavo;
    • Sánchez-Alcázar, José A.
    Publication type:
    journal article

  • Coenzyme Q 10 : Novel Formulations and Medical Trends.

    Published in:
    International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8432, doi. 10.3390/ijms21228432
    By:
    • Pastor-Maldonado, Carmen J.;
    • Suárez-Rivero, Juan M.;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Munuera-Cabeza, Manuel;
    • Suárez-Carrillo, Alejandra;
    • Talaverón-Rey, Marta;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Atherosclerosis and Coenzyme Q10.

    Published in:
    International Journal of Molecular Sciences, 2019, v. 20, n. 20, p. 5195, doi. 10.3390/ijms20205195
    By:
    • Suárez-Rivero, Juan M.;
    • Pastor-Maldonado, Carmen J.;
    • de la Mata, Mario;
    • Villanueva-Paz, Marina;
    • Povea-Cabello, Suleva;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Suárez-Carrillo, Alejandra;
    • Talaverón-Rey, Marta;
    • Munuera, Manuel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis.

    Published in:
    International Journal of Molecular Sciences, 2017, v. 18, n. 11, p. 2393, doi. 10.3390/ijms18112393
    By:
    • Povea-Cabello, Suleva;
    • Oropesa-Ávila, Manuel;
    • de la Cruz-Ojeda, Patricia;
    • Villanueva-Paz, Marina;
    • de la Mata, Mario;
    • Suárez-Rivero, Juan Miguel;
    • Álvarez-Córdoba, Mónica;
    • Villalón-García, Irene;
    • Cotán, David;
    • Ybot-González, Patricia;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation.

    Published in:
    Molecular Neurobiology, 2019, v. 56, n. 5, p. 3638, doi. 10.1007/s12035-018-1333-0
    By:
    • Álvarez-Córdoba, Mónica;
    • Fernández Khoury, Aida;
    • Villanueva-Paz, Marina;
    • Gómez-Navarro, Carmen;
    • Villalón-García, Irene;
    • Suárez-Rivero, Juan M.;
    • Povea-Cabello, Suleva;
    • de la Mata, Mario;
    • Cotán, David;
    • Talaverón-Rey, Marta;
    • Pérez-Pulido, Antonio J.;
    • Salas, Joaquín J.;
    • Pérez-Villegas, Eva Mª;
    • Díaz-Quintana, Antonio;
    • Armengol, José A.;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • Patient-Derived Cellular Models for Polytarget Precision Medicine in Pantothenate Kinase-Associated Neurodegeneration.

    Published in:
    Pharmaceuticals (14248247), 2023, v. 16, n. 10, p. 1359, doi. 10.3390/ph16101359
    By:
    • Álvarez-Córdoba, Mónica;
    • Talaverón-Rey, Marta;
    • Povea-Cabello, Suleva;
    • Cilleros-Holgado, Paula;
    • Gómez-Fernández, David;
    • Piñero-Pérez, Rocío;
    • Reche-López, Diana;
    • Munuera-Cabeza, Manuel;
    • Suárez-Carrillo, Alejandra;
    • Romero-González, Ana;
    • Romero-Domínguez, Jose Manuel;
    • López-Cabrera, Alejandra;
    • Armengol, José Ángel;
    • Sánchez-Alcázar, José Antonio
    Publication type:
    Article

  • Antioxidants Prevent Iron Accumulation and Lipid Peroxidation, but Do Not Correct Autophagy Dysfunction or Mitochondrial Bioenergetics in Cellular Models of BPAN.

    Published in:
    International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14576, doi. 10.3390/ijms241914576
    By:
    • Suárez-Carrillo, Alejandra;
    • Álvarez-Córdoba, Mónica;
    • Romero-González, Ana;
    • Talaverón-Rey, Marta;
    • Povea-Cabello, Suleva;
    • Cilleros-Holgado, Paula;
    • Piñero-Pérez, Rocío;
    • Reche-López, Diana;
    • Gómez-Fernández, David;
    • Romero-Domínguez, José Manuel;
    • Munuera-Cabeza, Manuel;
    • Díaz, Antonio;
    • González-Granero, Susana;
    • García-Verdugo, José Manuel;
    • Sánchez-Alcázar, José A.
    Publication type:
    Article

  • mtUPR Modulation as a Therapeutic Target for Primary and Secondary Mitochondrial Diseases.

    Published in:
    International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1482, doi. 10.3390/ijms24021482
    By:
    • Cilleros-Holgado, Paula;
    • Gómez-Fernández, David;
    • Piñero-Pérez, Rocío;
    • Reche-López, Diana;
    • Álvarez-Córdoba, Mónica;
    • Munuera-Cabeza, Manuel;
    • Talaverón-Rey, Marta;
    • Povea-Cabello, Suleva;
    • Suárez-Carrillo, Alejandra;
    • Romero-González, Ana;
    • Suárez-Rivero, Juan Miguel;
    • Romero-Domínguez, Jose Manuel;
    • Sánchez-Alcázar, Jose Antonio
    Publication type:
    Article