B-82 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest (THAPCA) and Cognitive Functioning: Case Studies.

Armstrong, P

Objective: Review of two cases of children who underwent THAPCA intervention following cardiac arrest and their cognitive functioning. The cases will attempt to demonstrate the outcome of use of THAPCA following cardiac arrest to improve neurocognitive outcomes. Method: Patient A (male) suffered cardiac arrest at 11 days of age and treated inpatient with THAPCA protocol. He presented with gross motor delay, did not sit unassisted until 9 months of age, and had three words at 12 months of age. Cognitive testing was administered at 14 months of age. Patient B (female) suffered a cardiac arrest at 2 months of age with 35 minutes of CPR and treated inpatient with THAPA protocol of cooling for 48 hours. Brain MRI was unremarkable. Cognitive testing was administered at 14 months of age. Results: Patients were administered the Mullen Scales of Early Learning per THAPCA cognitive protocol. Domains assessed were fine motor skills, visual reception skills, and receptive/expressive language skills. Patient A placed in the low average range with fine motor and visual reception skills and in the average range with receptive and expressive language skills. Patient B scored above average with fine motor, receptive/expressive language, and visual reception skills. Conclusion(s): The two cases illustrate cognitive outcomes following THAPCA intervention.

COGNITIVE ability; THERAPEUTIC hypothermia; COGNITION in children; MAGNETIC resonance imaging of the brain; HEALTH outcome assessment; CARDIAC arrest; THERAPEUTICS; MOTOR ability; PATIENTS

Archives of Clinical Neuropsychology, 2014, Vol 29, Issue 6, p567

0887-6177

Academic Journal

10.1093/arclin/acu038.170