Title

Growth Promoting Activity of Crude Protein Extract of Ruminant Placental Peptides.

Authors

Sami, Amtul Jamil; Ali, Muhammad; Shakoori, Abdul Rauf

Abstract

The placenta is a rich source of the peptide hormones, to cater the needs of the body during pregnancy, leading to a huge surge of physiological changes. It has been reported that the mammalian placenta produced placental growth hormone (during the last two trimesters replacing the normal growth hormone). Fresh placental tissue from Bubalus bubalis, Bos indicus and Capra hircus were collected and the total soluble proteins were extracted after washing and homogenizing in buffer pH 9.5. Total soluble proteins were isolated with ammonium sulfate after adjusting the at pH 8.0. The isolated peptide/protein extract from all the ruminant placentae were tested for growth promoting activity. It was found that administration of placental protein extract resulted in increase in the body weight and dimensions of the long bones, compared with the control subjects. It was also noticed that bubaline placental extract enhanced the growth at a higher rate compared with those of goat and cow.

Subjects

PEPTIDE hormones; CATTLE growth; PREGNANCY in mammals; ZEBUS; PLACENTA

Publication

Pakistan Journal of Zoology, 2014, Vol 46, Issue 2, p580

ISSN

0030-9923

Publication type

Academic Journal