Title

Antimicrobial activity of ethanolic, methanolic and hot aqueous extract of Punica granatum peel.

Authors

Panchal, Poonam; Mittal, Suchita; Dixit, Praveen K.

Abstract

The main objective of the study is to evaluate antibacterial activity of Punica granatum pericarp (peel) extracts (hot aqueous, methanolic and ethanolic) against E. coli and P. aeruginosa, using Zone of Inhibition (ZOI) and Minimum Inhibitory Concentration (MIC) method. Hot aqueous, methanolic and ethanolic extracts of P. granatum pericap showed an average inhibitory zone diameter of 21.5, 22.5 and 23mm respectively which indicates that ethanolic extract showed best result having ZOI greater than that of the standard antibiotic Tetracycline (20.1mm) against E. coli while hot aqueous, methanolic and ethanolic extracts of P. granatum pericap showed an average inhibitory zone diameter of 21, 23.5 and 25.5mm respectively which indicates that ethanolic extract showed best result having ZOI greater than that of the standard antibiotic Tetracycline (22.5 mm) against P. aeruginosa. P. granatum peel has MIC of 0.312 μg/ml against E. coli and 0.421 μg/ml against P. aeruginosa. Data revealed that ethanolic extract of P. granatum peel has shown highest antimicrobial activity as compared to other extracts.

Subjects

ANTI-infective agents; BIOCIDES; TETRACYCLINE; FOODBORNE diseases; ESCHERICHIA coli

Publication

International Journal of Pharmacy & Life Sciences, 2013, Vol 4, Issue 8, p2905

ISSN

0976-7126

Publication type

Academic Journal