Title

Antibacterial Activity of Ethanolic Leaf Extract of Andrographis paniculata Nees (Acanthaceae) and Its Bioactive Compound Andrographolide.

Authors

Abubacker, M. N.; Vasantha, S.

Abstract

The present study mainly focuses on the potential antibacterial value of ethanol leaf extract of Andrographis paniculata against pathogenic bacteria Escherichia coli, Klebsiella peneumoniae, Proteus vulgaris and Streptococcus pneumoniae by disc diffusion method. Bioactive compound andrographolide was isolated from the leaf. The results revealed that the ethanol leaf extract and andrographolide compound are potent in inhibiting these bacteria and this work highlights that the inhibitory effect is on par with standard antibiotics.

Subjects

ANTIBACTERIAL agents; BIOACTIVE compounds; ETHANOL; TREATMENT effectiveness; TREATMENT of escherichia coli diseases; KLEBSIELLA pneumoniae; STREPTOCOCCUS pneumoniae; THERAPEUTICS

Publication

Drug Invention Today, 2010, Vol 2, Issue 10, p440

ISSN

0975-7619

Publication type

Academic Journal