Title

Synthesis, Characterization, and Antioxidant Activity of Phloretin Isonicotinyl Hydrazone.

Authors

Li Jing; Yu Yan-ying; Cao Shu-wen

Abstract

To improve the biological activity of phloretin, a novel hydrazone was synthesis with phloretin and isoniazid, and the target compound was characterized by UV, IR, ¹H NMR, 13C NMR and elemental analysis, respectively. Reducing power, DPPH and ABTS ⋅ radical scavenging assays were carried out to evaluate the antioxidant and free radical scavenging abilities of phloretin and its hydrazone. The results showed that the antioxidant and free radical scavenging abilities of hydrazone was stronger than phloretin.

Subjects

ANTIOXIDANTS; PHENOLS; ORGANIC synthesis; HYDRAZONES; NUCLEAR magnetic resonance spectroscopy; FREE radicals; CHEMICAL reduction

Publication

Natural Product Research & Development, 2011, Vol 23, Issue 5, p824

ISSN

1001-6880

Publication type

Academic Journal