The Influence of Different Levels of Acute Calorie Restriction on Several Hematological and Biochemical Parameters in Wistar Rats.

Mănălăchioae, Radu; Sarpataki, Orsolya; Prodan, Iulia; Sevastre, Bogdan; Marcus, Ioan

Calorie Restriction (CR) is a diet in which calorie intake is reduced, also defined as under-nutrition without malnutrition. In this experiment we used two levels of calorie restriction: 25% and 40% of calorie intake reduction than normal. We used 24 male Wistar rats, divided in 4 groups: ad libitum fed, 100% of normal calorie intake, 75% and 60% of normal calorie intake, for a period of 30 days. After harvesting the blood samples and hematological and biochemical analisys of the blood, we statistically interpreted them by calculating the mean, standard deviation, standard eror of the mean and "t' test (Student). After the statistical interpretation of the result, we concluded that acute mild and moderate CR did not have any negative effects on hematological and biochemical parameters comprised in this study. Moreover, it suggests beneficial effects regarding the fat and glucose metabolisms.

LOW-calorie diet; LABORATORY rats; ANIMAL feeding behavior; ANIMAL nutrition; HEMATOLOGY

Bulletin of the University of Agricultural Sciences & Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2011, Vol 68, Issue 1, p207

1843-5270

Academic Journal