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- Title
Inhibitory Effects of Three New Rutin Esters on Oxidative Modification of Lecithin Induced by Fe<sup>2 </sup>.
- Authors
DUAN Yu; DU Zong-liang; WU Da-cheng
- Abstract
Esterification of the hydroxyl groups of flavonoid glucosides by fatty acids is a possible way to improve the hydrophilic and antioxidant properties of flavonoid glucosides. The aim of the present work was to evaluate in vitro the antioxidant properties of three hew semisynthetic rutin derivatives, rutin-4′″-O-stearate (RS), rutin-4′″-O-laurate (RL) and rutin-4′″-O-caproate(RC), obtained by esterification of 4-OH in the rhamnose moiety. The antioxidant activities of rutin and the three esters were assessed using the content of thiobabiturirc acid reactive substances(TBARS) as index, and the inhibitory effects on oxidative modification of lecithin induced by Fe2 were compared. The results showed that three rutin esters could inhibit the oxidation and the role of both RL and RC were better than that of rutin; RC showed the highest efficiency. The findings demonstrated that the esterification of 4-OH in the rhamnose moiety may improve the antioxidant activity of rutin.
- Subjects
RUTIN; ESTERS; LECITHIN; ESTERIFICATION; FLAVONOIDS; GLUCOSIDES; FATTY acids; ANTIOXIDANTS
- Publication
Natural Product Research & Development, 2009, Vol 21, Issue 4, p586
- ISSN
1001-6880
- Publication type
Academic Journal