Title

Extraction of ecdysteron-80 from Serratula coronata L. and assessment of its pharmacological action. Part I. Adaptogenic, gastroprotective, thermoprotective, and antihypoxic activity.

Authors

Punegov, V. V.; Sychov, R. L.; Zainullin, V. G.; Fedorov, V. N.; Punegova, N. V.

Abstract

A method for extracting ecdysteroids from Serratula coronata L. for the new phytopreparation Edcysterone-80 is proposed. Experiments on white rats established that this preparation has pronounced adaptogenic, antihypoxic, gastroprotective, and thermoprotective properties. Results of this study can be applied both in basic research and in the development of production technology for the new pharmaceutical preparation based on ecdysteroids of Serratula coronata.

Subjects

STEROIDS; PHARMACOLOGY; DRUGS; EXTRACTION (Chemistry); CHEMICAL properties

Publication

Pharmaceutical Chemistry Journal, 2008, Vol 42, Issue 8, p446

ISSN

0091-150X

Publication type

Academic Journal

DOI

10.1007/s11094-008-0159-x