Title

Polyhexamethylene biguanide versus saline on microbial load in wounds: a systematic review protocol.

Authors

Garcia, Priscila Gleice Mariano; Pessanha, Fernanda Soares; Pires, Bruna Maiara Ferreira Barreto; de Oliveira, Beatriz Guitton Renaud Baptista

Abstract

Objective: To analyze the effectiveness of polyhexamethylene biguanide (PHMB) compared to saline on the microbial load of wounds. Method: Systematic review protocol, built according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) and the Joanna Briggs Institute's (JBI) methodology. Studies will be evaluated by two independent researchers in the following databases: Latin America and the Caribbean Literature on Health Sciences (LILACS), Nursing Database (BDENF), Medical Literature Analysis and Retrieval System Online (MEDLINE), and Excerpta Medica Database (Embase). Studies published in Portuguese, English, or Spanish will be included, and the search will not be restricted by publication date. Animal or in vitro studies, reviews, letters to the editor, and case studies will be excluded. After selecting studies, data extraction will take place systematically, and the corresponding records will be presented in a narrative and tabular way.

Subjects

SYSTEMATIC reviews; ANTI-infective agents; PHYSIOLOGIC salines; WOUND care; MICROBIAL contamination

Publication

Online Brazilian Journal of Nursing, 2023, Vol 22, p10

ISSN

1676-4285

Publication type

Academic Journal