Title

The Role of Green Tea Extract on Inhibiting Porphyromonas gingivalis as a Major Periodontitis Pathogen: In Vitro Study.

Authors

Fajriani; Sartini, Sartini; Handayani, Hendrastuti; Putri, Dekarini Dwi

Abstract

Porphyromonas gingivalis is one of the anaerobic bacteria that are found in patients with periodontitis. Green tea catechins have antibacterial activity against several oral pathogenic bacteria. This study aimed to determine the ability of the green tea extract fraction to inhibit the growth of P. gingivalis. The green tea powder was extracted with hexane by maceration, then the insoluble fraction of the hexane was extracted using high-pressure extraction with water as a solvent ratio of 1:10. Antibacterial activity test was carried out by agar dilution method and agar diffusion disk using Mueller-Hinton Agar (MHA) media. The results showed that green tea extract had antibacterial activity against P. gingivalis with an inhibitory value of at least 0.5% (5mg / ml) and an average diameter of the zone of inhibition at a concentration of 4 mg/disc of 16.16 mm. This study concludes that green tea extract can be made in a dosage form to prevent periodontitis.

Subjects

GREEN tea; TEA extracts; PORPHYROMONAS gingivalis; AGAR; PERIODONTITIS; ANAEROBIC bacteria

Publication

Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 8, p152

ISSN

0975-8453

Publication type

Academic Journal