Title

PPARα activation by fenofibrate ameliorates radiation‐induced skin injury.

Authors

Liu, P.; Yu, D.; Sheng, W.; Geng, F.; Zhang, J.; Zhang, S.

Abstract

PPAR activation by fenofibrate ameliorates radiation-induced skin injury Ionizing radiation induces cutaneous lipid remolding and skin adipocytes confer protection against radiation-induced skin injury. After 7 days, skin dermatitis and ulcers were relieved in the fenofibrate-treated skin but not in the saline-treated skin (Fig.

Subjects

RADIATION injuries; SKIN injuries; FENOFIBRATE; NUCLEAR receptors (Biochemistry); TOTAL body irradiation

Publication

Journal of the European Academy of Dermatology & Venereology, 2022, Vol 36, Issue 3, pe207

ISSN

0926-9959

Publication type

Academic Journal

DOI

10.1111/jdv.17745