Title

Estimation of Red Blood Cell Parameters and Serum Prohepcidin Level in Generalised Chronic Periodontitis Patients before and after Non-Surgical Periodontal therapy.

Authors

D., Vandana; Anand, Nithya; Deepika, Kalicheti; Gita, Bagavad; Paddmanaban, Preethe; Ramya

Abstract

Background: The Anaemia of chronic disease (ACD) is a prevalent, poorly understood condition that afflicts patients with a wide variety of diseases, including infections, malignancies and rheumatologic disorders. Materials and Method: 40 patients 20-65 years of age with chronic periodontitis were assessed before and after periodontal therapy for Hb, ESR, Erythrocyte count, MCV, MCH, MCHC and PROHEPCIDIN (ELISA). Results: A significant (p<.000) increase in RBC (4.581) and Hb (12.77) values were estimated after SRP compared to baseline. Prohepcidin levels decreased insignificantly after SRP. Tailed t test results shows significant correlation at the 0.01 level between RBC parameters but no significance between probing depth or prohepcidin values with RBC parameters. Conclusion: The results conclude that reduction in periodontal inflammation by scaling and root planning improves RBC count and hemoglobin level significantly Prohepcidin levels decreases with periodontal treatment but rather insignificantly.

Subjects

TOOTH root planing; ERYTHROCYTES; AGGRESSIVE periodontitis; SERUM; PERIODONTITIS

Publication

Indian Journal of Public Health Research & Development, 2019, Vol 10, Issue 11, p3285

ISSN

0976-0245

Publication type

Academic Journal

DOI

10.5958/0976-5506.2019.04430.9