Comparing the Effect of Dextrose and Oxytocin to Reduce Postpartum Haemorrhage: Randomised Controlled Trial.

SUHRABI, ZAINAB; AKBARI, MALIHE; TAGHINEJAD, HAMID; AZAMI, GOLNAZ

Introduction: Post-partum haemorrhage is a leading cause of maternal mortality and morbidity worldwide. There are different management procedures adopted for the treatment of postpartum haemorrhage. Aim: To evaluate the efficacy of dextrose in Post-partum Haemorrhage (PPH) and compare it with Oxytocin (a conventional method). Materials and Methods: A two-arm randomised controlled trial was conducted among 120 pregnant women admitted to the delivery room of the Obstetric and Gynaecological Unit of a Teaching Hospital. Participants were randomised to receive either 20 unit of oxytocin in 1000 mL ringer lactate solution (routine administration, control group) or 200 mL of 10% dextrose solution (intervention group). The primary outcome measured in this study was amount of blood loss. The outcome was assessed at 1 hour and 2 hours. Data were analysed using SPSS version 22.0, chi-square and student's t-tests. Authors used expected maximisation to handle missing data to enable an intention-to-treat analysis. Results: At baseline, the groups were homogeneous in regards to socio-demographic variables. The average blood loss was significantly lower in the intervention group (dextrose 10%) compared to the control group (oxytocin) (p<0.05). Conclusion: Administering of dextrose 10% to pregnant women at the third stage of labour was associated with lower postpartum haemorrhage than oxytocin.

OXYTOCIN; DEXTROSE; PHYSIOLOGIC salines; MATERNAL mortality; PREGNANT women

Journal of Clinical & Diagnostic Research, 2019, Vol 13, Issue 7, p9

0973-709X

Academic Journal

10.7860/JCDR/2019/35479.12987