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Title: IS DEEP BRAIN STIMULATION A VIABLE TREATMENT FOR SUBSTANCE-RELATED ADDICTION?
Authors: Guzzi, Giusy; Lavano, Angelo; Lavano, Serena Marianna; Marotta, Rosa
Abstract: For the ability to modulate the activity of dysregulated networks Deep Brain Stimulation (DBS) of areas involved in reward system and motivational states may have a potential application in addiction despite risks associated with its invasiveness. To date nucleus accumbens core (NAcc) appares to be the most effective target but also anteromedial portion of subthalamic nucleus (STN) and lateral hypothalamus (LH) are studied for clinical purposes. The choice of the target may vary based on the form of addiction: NAcc in alcohol and opiate addiction and STN in cocaine addict patients. Additional studies are still necessary to establish effectiveness and safety of DBS in addiction.
Subjects: DEEP brain stimulation; THERAPEUTICS; ADDICTIONS; SUBTHALAMIC nucleus; NUCLEUS accumbens
Publication: Romanian Journal of Neurology, 2019, Vol 18, Issue 1, p5
ISSN: 1843-8148
Publication type: Academic Journal
DOI: 10.37897/rjn.2019.1.1

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IS DEEP BRAIN STIMULATION A VIABLE TREATMENT FOR SUBSTANCE-RELATED ADDICTION?