Title

Clinical study on the influence of phloroglucinol on plasma angiotensin II and D-Dimer index in patients with severe pregnancy-induced hypertension.

Authors

Liang Ai; Xinzhi Lan; Limin Wang; Yanjie Xu; Bin Zhang

Abstract

To observe the effect of phloroglucinol on plasma angiotensin II and D-dimer index when it was applied to patients with severe pregnancy-induced hypertension. 212 cases of severe pregnancy-induced hypertension patients diagnosed clinically were selected to be randomly divided into the research group and the control group. The research groups were given phloroglucinol, while the control group were given magnesium sulfate. The plasma angiotensin II and D-dimer index in patients were detected before treatment and after 7 days respectively with statistical analysis of results. The diffidence after treatment was statistically significant (P0.05). It showed that the research group could reduce the plasma D-dimer and angiotensin II index in severe pregnancy-induced hypertension patients, and its effect was significantly better than the control group, according to the plasma D-dimer and angiotensin II index changes in patients, it indicated that it was effective of phloroglucinol treatment for patients with pregnancy-induced hypertension disease and superior to the western medicine conventional treatment, worth clinical promotion.

Subjects

HYPERTENSION in pregnancy; PHLOROGLUCINOL; ANGIOTENSIN II; FIBRIN fragment D; MAGNESIUM sulfate; QUANTITATIVE research; THERAPEUTICS

Publication

Pakistan Journal of Pharmaceutical Sciences, 2016, Vol 29, p1375

ISSN

1011-601X

Publication type

Academic Journal