Title

In Vitro Antioxidant Evaluation of Some Mannich Bases which Contain Bis-1,2,4 -Triazole Derivative.

Authors

Parlak, Akif Evren; Karatepe, Mustafa; Koparır, Metin; Dastan, Sevgi Durna; Alayunt, Naci Omer; Ulas, Mustafa; Keser, Serhat; Celik, Sait

Abstract

This study aims to examine the antioxidant effects of some Mannich bases containing bis-1, 2, 4 triazole, which are synthesized afresh. The antioxidant activities of the derivatives were measured using different methods in this study, including reducing power capacity, metal chelating activity, superoxide anion radicals scavenging activity, H2O2 scavenging activity and hydroxyl radical scavenging. As a result, derivatives had efficient antioxidant and free radical scavenging activity when compared to ascorbic acid, BHT and α-tocopherol as associated antioxidants.

Subjects

ANTIOXIDANTS; MANNICH bases; TRIAZOLE derivatives; TRIAZOLES synthesis; CHELATION; HYDROXYL group; VITAMIN C

Publication

Journal of the Chemical Society of Pakistan, 2015, Vol 37, Issue 6, p1192

ISSN

0253-5106

Publication type

Academic Journal