Title

Effects of Crude Extract of Poria cocos on the Tension of Jejunum and Cecum in Rabbits ia viiro.

Authors

Jun WANG; Yongshuai PENG; Fengsun WU; Jun HUO

Abstract

[ Objective] This study aimed to investigate the effects of crude extract of Poria cocos on intestina smooth muscle contraction of rabbits in vitro and reveal the related mechanism. [Method] With in vitro experimental method, using the tension of jejunal and ceca smooth muscle as an indicator, 3.75, 7.50, 15. 00, and 22.5 g/L crude extract of P. cocos were added into Tyrode's solution of jeeunum and cecum tissues of rabbits to observe the effects of crude extract of P. cocos on motion dynamics of jeeunum and cecum of rabbits. [Result] The addition of crude extract of P. cocos could inhibit the contraction of jee'una and cecal smooth muscle of rabbits in vitro, enhance contraction tension and relaxation tension, and reduce contraction amplitude. The effects were improved as the dose of crude extract of P. cocos increaed, displaying a dose-effect relationship. [Conclusion] This study provided theoretical bais for the clinical use of P. cocos.

Subjects

PORIA cocos; EDIBLE fungi; JEJUNUM; CECUM; RABBITS

Publication

Agricultural Biotechnology (2164-4993), 2015, Vol 4, Issue 5, p54

ISSN

2164-4993

Publication type

Academic Journal