Title

Синтез та антимжробна активність водонерозчинних юнних рiдин з катiоном 1-алкiл-3-метилiмiдазолiю.

Authors

Hodyna, D. M.; Metelytsia, L. A.; Parkhomenko, V. I.; Rogalsky, S. P.

Abstract

Water-insoluble Ionic liquids based on 1-alkyl-3-methylimidazolium cation comprising C6, C8, C12 and C16 alkyl radicals and tetrafluoroborate anion have been synthesized. The antimicrobial activity of ionic liquids was investigated against test cultures, Staphylococcus aureus (ATCC-25923), Escherichia coli (ATCC-25922), Pseudomonas aeruginosa (ATCC-27853), Candida albicans (M 885 ATCC 10231) and clinical isolates, Candida albicans, Candida glabrata and Candida krusei. It was found that 1-dodecyl-3-methylimidazolium tetrafluoroborate possesses highest activity against bacteria and fungi in a concentration of 1.0%, while the salt with 1-hexyl-3-methylimidazolium cation didn't indicate any antimicrobial activity. The ionic liquid with 1-octyl-3-methylimidazolium cation showed selective antifungal activity.

Publication

Ukrainica Bioorganica Acta, 2014, Vol 12, Issue 1, p18

ISSN

1814-9758

Publication type

Academic Journal