Works matching AU Hediger, Matthias A.

Results: 59

Expression cloning and characterization of a renal electrogenic Na/HCO3 cotransporter.

Published in:

Nature, 1997, v. 387, n. 6631, p. 409, doi. 10.1038/387409a0

By:

Romero, Michael F.;
Hediger, Matthias A.

Publication type:

Article

Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid.

Published in:

Nature, 1993, v. 366, n. 6455, p. 575, doi. 10.1038/366575a0

By:

Brown, Edward M.;
Gamba, Gerardo;
Riccardi, Daniela;
Lombardi, Michael;
Butters, Robert;
Kifor, Olga;
Sun, Adam;
Hediger, Matthias A.;
Lytton, Jonathan;
Hebert, Steven C.

Publication type:

Article

Primary structure and functional characterization of a high-affinity glutamate transporter.

Published in:

Nature, 1992, v. 360, n. 6403, p. 467, doi. 10.1038/360467a0

By:

Kanai, Yoshikatsu;
Hediger, Matthias A.

Publication type:

Article

Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation.

Published in:

Cancers, 2023, v. 15, n. 1, p. 203, doi. 10.3390/cancers15010203

By:

Sanchez-Collado, Jose;
Nieto-Felipe, Joel;
Jardin, Isaac;
Bhardwaj, Rajesh;
Berna-Erro, Alejandro;
Salido, Gines M.;
Smani, Tarik;
Hediger, Matthias A;
Lopez, Jose J.;
Rosado, Juan A.

Publication type:

Article

Orai1 Boosts SK3 Channel Activation.

Published in:

Cancers, 2021, v. 13, n. 24, p. 6357, doi. 10.3390/cancers13246357

By:

Tiffner, Adéla;
Hopl, Valentina;
Schober, Romana;
Sallinger, Matthias;
Grabmayr, Herwig;
Höglinger, Carmen;
Fahrner, Marc;
Lunz, Victoria;
Maltan, Lena;
Frischauf, Irene;
Krivic, Denis;
Bhardwaj, Rajesh;
Schindl, Rainer;
Hediger, Matthias A.;
Derler, Isabella

Publication type:

Article

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1.

Published in:

Molecular Oncology, 2021, v. 15, n. 10, p. 2782, doi. 10.1002/1878-0261.12999

By:

Kandasamy, Palanivel;
Zlobec, Inti;
Nydegger, Damian T.;
Pujol-Giménez, Jonai;
Bhardwaj, Rajesh;
Shirasawa, Senji;
Toshiyuki Tsunoda;
Hediger, Matthias A.

Publication type:

Article

Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism.

Published in:

Annals of Neurology, 2019, v. 85, n. 6, p. 921, doi. 10.1002/ana.25477

By:

Stergachis, Andrew B.;
Pujol‐Giménez, Jonai;
Gyimesi, Gergely;
Fuster, Daniel;
Albano, Giusppe;
Troxler, Marina;
Hediger, Matthias A.;
Picker, Jonathan;
Rodan, Lance H.;
Rosenberg, Paul A.;
Bergin, Ann;
Peters, Jurriaan;
El Achkar, Christelle Moufawad;
Harini, Chellamani;
Rotenberg, Alexander;
Manzi, Shannon

Publication type:

Article

Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism.

Published in:

2019

By:

Stergachis, Andrew B;
Pujol-Giménez, Jonai;
Gyimesi, Gergely;
Fuster, Daniel;
Albano, Giusppe;
Troxler, Marina;
Picker, Jonathan;
Rosenberg, Paul A;
Bergin, Ann;
Peters, Jurriaan;
El Achkar, Christelle Moufawad;
Harini, Chellamani;
Manzi, Shannon;
Rotenberg, Alexander;
Hediger, Matthias A;
Rodan, Lance H

Publication type:

journal article

Transporter-Mediated Drug Delivery.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1151, doi. 10.3390/molecules28031151

By:

Gyimesi, Gergely;
Hediger, Matthias A.

Publication type:

Article

Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library.

Published in:

ChemMedChem, 2021, v. 16, n. 21, p. 3306, doi. 10.1002/cmdc.202100467

By:

Pujol‐Giménez, Jonai;
Poirier, Marion;
Bühlmann, Sven;
Schuppisser, Céline;
Bhardwaj, Rajesh;
Awale, Mahendra;
Visini, Ricardo;
Javor, Sacha;
Hediger, Matthias A.;
Reymond, Jean‐Louis

Publication type:

Article

Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 49, p. 14748, doi. 10.1002/anie.201507320

By:

Simonin, Céline;
Awale, Mahendra;
Brand, Michael;
van Deursen, Ruud;
Schwartz, Julian;
Fine, Michael;
Kovacs, Gergely;
Häfliger, Pascal;
Gyimesi, Gergely;
Sithampari, Abilashan;
Charles, Roch‐Philippe;
Hediger, Matthias A.;
Reymond, Jean‐Louis

Publication type:

Article

Iron transport: emerging roles in health and disease.

Published in:

Biochemistry & Cell Biology, 2002, v. 80, n. 5, p. 679, doi. 10.1139/o02-159

By:

Goswami, Tapasree;
Rolfs, Andreas;
Hediger, Matthias A

Publication type:

Article

Investigation of the Inhibitory Effects of the Benzodiazepine Derivative, 5-BDBD on P2X4 Purinergic Receptors by two Complementary Methods.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2013, v. 32, n. 1, p. 11, doi. 10.1159/000350119

By:

Balázs, Bernadett;
Dankó, Tamás;
Kovács, Gergely;
Köles, László;
Hediger, Matthias a.;
Zsembery, Ákos

Publication type:

Article

Structure, regulation and physiological roles of urea transporters.

Published in:

1996

By:

Hediger, Matthias A.;
Smith, Craig P.;
Guofeng You;
Wen-Sen Lee;
Kanai, Yoshikatsu;
Shayakul, Chairat;
Hediger, M A;
Smith, C P;
You, G;
Lee, W S;
Kanai, Y;
Shayakul, C

Publication type:

journal article

New view at C.

Published in:

Nature Medicine, 2002, v. 8, n. 5, p. 445, doi. 10.1038/nm0502-445

By:

Hediger, Matthias A.

Publication type:

Article

Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method.

Published in:

Angewandte Chemie, 2015, v. 127, n. 49, p. 14961, doi. 10.1002/ange.201507320

By:

Simonin, Céline;
Awale, Mahendra;
Brand, Michael;
van Deursen, Ruud;
Schwartz, Julian;
Fine, Michael;
Kovacs, Gergely;
Häfliger, Pascal;
Gyimesi, Gergely;
Sithampari, Abilashan;
Charles, Roch ‐ Philippe;
Hediger, Matthias A.;
Reymond, Jean ‐ Louis

Publication type:

Article

Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application.

Published in:

Pflügers Archiv: European Journal of Physiology, 2020, v. 472, n. 9, p. 1177, doi. 10.1007/s00424-020-02433-x

By:

Gyimesi, Gergely;
Pujol-Giménez, Jonai;
Kanai, Yoshikatsu;
Hediger, Matthias A.

Publication type:

Article

The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.912277

By:

Verouti, Sophia N.;
Pujol-Giménez, Jonai;
Bermudez-Lekerika, Paola;
Scherler, Laeticia;
Bhardwaj, Rajesh;
Thomas, Aurélien;
Lenglet, Sébastien;
Siegrist, Mark;
Hofstetter, Willy;
Fuster, Daniel G.;
Hediger, Matthias A.;
Escher, Geneviève;
Vogt, Bruno

Publication type:

Article

The Less Well-Known Little Brothers: The SLC9B/NHA Sodium Proton Exchanger Subfamily—Structure, Function, Regulation and Potential Drug-Target Approaches.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.898508

By:

Anderegg, Manuel A.;
Gyimesi, Gergely;
Ho, Tin Manh;
Hediger, Matthias A.;
Fuster, Daniel G.

Publication type:

Article

The Primary Structure of the Mesophilic Lactate Dehydrogenase from Bacillus subtilis.

Published in:

Biological Chemistry, 1986, v. 367, n. 2, p. 891

By:

HEDIGER, Matthias A.;
FRANK, Gerhard;
ZUBER, Herbert

Publication type:

Article

CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells.

Published in:

Journal of Physiology, 2004, v. 557, n. 1, p. 121, doi. 10.1113/jphysiol.2004.062653

By:

Kahr, Heike;
Schindl, Rainer;
Fritsch, Reinhard;
Heinze, Barbara;
Hofbauer, Michael;
Hack, Marlene E.;
Mörtelmaier, Manuel A.;
Groschner, Klaus;
Peng, Ji-Bin;
Takanaga, Hitomi;
Hediger, Matthias A.;
Romanin, Christoph

Publication type:

Article

Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond.

Published in:

Journal of Physiology, 2003, v. 551, n. 3, p. 729, doi. 10.1111/j.1469-7793.2003.00729.x

By:

Peng, Ji-Bin;
Brown, Edward M.;
Hediger, Matthias A.

Publication type:

Article

Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93552-7

By:

Havukainen, Sami;
Pujol-Giménez, Jonai;
Valkonen, Mari;
Westerholm-Parvinen, Ann;
Hediger, Matthias A.;
Landowski, Christopher P.

Publication type:

Article

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter.

Published in:

1999

By:

Trotti, Davide;
Rolfs, Andreas;
Danbolt, Niels C.;
Brown, Robert H.;
Hediger, Matthias A.

Publication type:

Correction Notice

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter.

Published in:

Nature Neuroscience, 1999, v. 2, n. 5, p. 427, doi. 10.1038/8091

By:

Trotti, Davide;
Rolfs, Andreas;
Danbolt, Niels C.;
Brown, Robert H.;
Hediger, Matthias A.

Publication type:

Article

Systematic in silico discovery of novel solute carrier-like proteins from proteomes.

Published in:

PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0271062

By:

Gyimesi, Gergely;
Hediger, Matthias A.

Publication type:

Article

Chemical Inhibitors of the Calcium Entry Channel TRPV6.

Published in:

Pharmaceutical Research, 2011, v. 28, n. 2, p. 322, doi. 10.1007/s11095-010-0249-9

By:

Landowski, Christopher;
Bolanz, Katrin;
Suzuki, Yoshiro;
Hediger, Matthias

Publication type:

Article

Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5604, doi. 10.3390/ijms21165604

By:

Schild, Achille;
Bhardwaj, Rajesh;
Wenger, Nicolas;
Tscherrig, Dominic;
Kandasamy, Palanivel;
Dernič, Jan;
Baur, Roland;
Peinelt, Christine;
Hediger, Matthias A.;
Lochner, Martin

Publication type:

Article

Vitamin D.

Published in:

Annals of the New York Academy of Sciences, 2007, v. 1116, p. 340, doi. 10.1196/annals.1402.070

By:

CHRISTAKOS, SYLVIA;
DHAWAN, PUNEET;
BENN, BRYAN;
PORTA, ANGELA;
HEDIGER, MATTHIAS;
OH, GOO T.;
JEUNG, EUI‐BAE;
ZHONG, YAN;
AJIBADE, DARE;
DHAWAN, KOPAL;
JOSHI, SNEHA

Publication type:

Article

Gateway to a long life?

Published in:

Nature, 2002, v. 417, n. 6887, p. 393, doi. 10.1038/417393a

By:

Hediger, Matthias A.

Publication type:

Article

CaT1 manifests the pore properties of the calcium-release-activated calcium channel.

Published in:

Nature, 2001, v. 410, n. 6829, p. 705, doi. 10.1038/35070596

By:

Lixia Yue;
Ji-Bin Peng;
Hediger, Matthias A.;
Clapham, David E.

Publication type:

Article

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.

Published in:

Nature, 1999, v. 401, n. 6751, p. 383, doi. 10.1038/43910

By:

Chen, Xing-Zhen;
Vassilev, Peter M.;
Basora, Nuria;
Peng, Ji-Bin;
Nomura, Hideki;
Segal, Yoav;
Brown, Edward M.;
Reeders, Stephen T.;
Hediger, Matthias A.;
Zhou, Jing

Publication type:

Article

A family of mammalian Na+-dependent L-ascorbic acid transporters.

Published in:

Nature, 1999, v. 399, n. 6731, p. 70, doi. 10.1038/19986

By:

Tsukaguchi, Hiroyasu;
Tokui, Taro;
Mackenzie, Bryan;
Berger, Urs V.;
Xing-Zhen Chen;
Yangxi Wang;
Brubaker, Richard F.;
Hediger, Matthias A.

Publication type:

Article

Metal ion transporters in mammals: structure, function and pathological implications.

Published in:

Journal of Physiology, 1999, v. 518, n. 1, p. 1, doi. 10.1111/j.1469-7793.1999.0001r.x

By:

Rolfs, Andreas;
Hediger, Matthias A.

Publication type:

Article

Calcium Channel TRPV6 Is Involved in Murine Maternal--Fetal Calcium Transport.

Published in:

Journal of Bone & Mineral Research, 2008, v. 23, n. 8, p. 1249, doi. 10.1359/jbmr.080314

By:

Suzuki, Yoshiro;
Kovacs, Christopher S.;
Takanaga, Hitomi;
Ji-Bin Peng;
Landowski, Christopher P.;
Hediger, Matthias A.

Publication type:

Article

Marked Disturbance of Calcium Homeostasis in Mice With Targeted Disruption of the Trpv6 Calcium Channel Gene.

Published in:

Journal of Bone & Mineral Research, 2007, v. 22, n. 2, p. 274, doi. 10.1359/JBMR.061110

By:

Bianco, Suzy D. C.;
Ji-Bin Peng;
Takanaga, Hitomi;
Suzuki, Yoshiro;
Crescenzi, Alessandra;
Kos, Claudine H.;
Liyan Zhuang;
Freeman, Michael R.;
Gouveia, Cecilia H. A.;
Jiangping Wu;
Hongyu Luo;
Mauro, Theodora;
Brown, Edward M.;
Hediger, Matthias A.

Publication type:

Article

Functional characterization of a highly specific l-arabinose transporter from Trichoderma reesei.

Published in:

Microbial Cell Factories, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12934-021-01666-4

By:

Havukainen, Sami;
Pujol-Giménez, Jonai;
Valkonen, Mari;
Hediger, Matthias A.;
Landowski, Christopher P.

Publication type:

Article

Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 11, p. 1613, doi. 10.1093/hmg/ddn048

By:

Suzuki, Yoshiro;
Pasch, Andreas;
Bonny, Olivier;
Mohaupt, Markus G.;
Hediger, Matthias A.;
Frey, Felix J.

Publication type:

Article

Applications of the Microscale Thermophoresis Binding Assay in COVID-19 Research.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 7, p. 1432, doi. 10.3390/v15071432

By:

Nydegger, Damian T.;
Pujol-Giménez, Jonai;
Kandasamy, Palanivel;
Vogt, Bruno;
Hediger, Matthias A.

Publication type:

Article

Expression, Purification, and Structural Insights for the Human Uric Acid Transporter, GLUT9, Using the Xenopus laevis Oocytes System.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0108852

By:

Clémençon, Benjamin;
Lüscher, Benjamin P.;
Fine, Michael;
Baumann, Marc U.;
Surbek, Daniel V.;
Bonny, Olivier;
Hediger, Matthias A.

Publication type:

Article

Expression, Purification and Low-Resolution Structure of Human Vitamin C Transporter SVCT1 (SLC23A1).

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076427

By:

Boggavarapu, Rajendra;
Jeckelmann, Jean-Marc;
Harder, Daniel;
Schneider, Philipp;
Ucurum, Zöhre;
Hediger, Matthias;
Fotiadis, Dimitrios

Publication type:

Article

Frog Oocytes to Unveil the Structure and Supramolecular Organization of Human Transport Proteins.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0021901

By:

Bergeron, Marc J.;
Boggavarapu, Rajendra;
Meury, Marcel;
Ucurum, Zöhre;
Caron, Luc;
Isenring, Paul;
Hediger, Matthias A.;
Fotiadis, Dimitrios

Publication type:

Article

Differential distribution of the glutamate transporters GLT-1 and GLAST in tanycytes of the third ventricle.

Published in:

Journal of Comparative Neurology, 2001, v. 433, n. 1, p. 101, doi. 10.1002/cne.1128

By:

Berger, Urs V.;
Hediger, Matthias A.

Publication type:

Article

Distribution of the glutamate transporters GLAST and GLT-1 in rat circumventricular organs, meninges, and dorsal root ganglia.

Published in:

Journal of Comparative Neurology, 2000, v. 421, n. 3, p. 385, doi. 10.1002/(SICI)1096-9861(20000605)421:3<385::AID-CNE7>3.0.CO;2-S

By:

Berger, Urs V.;
Hediger, Matthias A.

Publication type:

Article

Molecular genetics of cystinuria: Mutation analysis of SLC3A1 and evidence for another gene in the Type I (silent) phenotype.

Published in:

Kidney International, 1998, v. 54, n. 1, p. 48, doi. 10.1046/j.1523-1755.1998.00956.x

By:

Saadi, Irfan;
Xing-Zhen Chen;
Hediger, Matthias;
Ong, Patricia;
Pereira, Perpetual;
Goodyear, Paul;
Rozen, Rima

Publication type:

Article

Divalent metal-ion transporter DMT1 mediates both H+ -coupled Fe2+ transport and uncoupled fluxes.

Published in:

Pflügers Archiv: European Journal of Physiology, 2006, v. 451, n. 4, p. 544, doi. 10.1007/s00424-005-1494-3

By:

Mackenzie, Bryan;
Ujwal, M. L.;
Min-Hwang Chang;
Romero, Michael F.;
Hediger, Matthias A.

Publication type:

Article

Sodium-dependent ascorbic acid transporter family SLC23.

Published in:

Pflügers Archiv: European Journal of Physiology, 2004, v. 447, n. 5, p. 677, doi. 10.1007/s00424-003-1104-1

By:

Takanaga, Hitomi;
Mackenzie, Bryan;
Hediger, Matthias A.

Publication type:

Article

The SLC14 gene family of urea transporters.

Published in:

Pflügers Archiv: European Journal of Physiology, 2004, v. 447, n. 5, p. 603, doi. 10.1007/s00424-003-1124-x

By:

Shayakul, Chairat;
Hediger, Matthias A.

Publication type:

Article

SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1.

Published in:

Pflügers Archiv: European Journal of Physiology, 2004, v. 447, n. 5, p. 571, doi. 10.1007/s00424-003-1141-9

By:

Mackenzie, Bryan;
Hediger, Matthias A.

Publication type:

Article

The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects.

Published in:

Pflügers Archiv: European Journal of Physiology, 2004, v. 447, n. 5, p. 469, doi. 10.1007/s00424-003-1146-4

By:

Kanai, Yoshikatsu;
Hediger, Matthias A.

Publication type:

Article