Works matching DE "MATRIPTASE"

Results: 57

The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.

Published in:

Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-15415-4

By:

Wu, Shang-Ru;
Teng, Chen-Hsin;
Tu, Ya-Ting;
Ko, Chun-Jung;
Cheng, Tai-Shan;
Lan, Shao-Wei;
Lin, Hsin-Ying;
Lin, Hsin-Hsien;
Tu, Hsin-Fang;
Hsiao, Pei-Wen;
Huang, Hsiang-Po;
Chen, Chung-Hsin;
Lee, Ming-Shyue

Publication type:

Article

Matriptase-Induced Phosphorylation of MET is Significantly Associated with Poor Prognosis in Invasive Bladder Cancer; an Immunohistochemical Analysis.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3708, doi. 10.3390/ijms19123708

By:

Yamasaki, Koji;
Mukai, Shoichiro;
Nagai, Takahiro;
Nakahara, Kozue;
Fujii, Masato;
Terada, Naoki;
Ohno, Akinobu;
Sato, Yuichiro;
Toda, Yoshinobu;
Kataoka, Hiroaki;
Kamoto, Toshiyuki

Publication type:

Article

Whole-exome sequencing diagnosis of two autosomal recessive disorders in one family.

Published in:

British Journal of Dermatology, 2015, v. 172, n. 5, p. 1407, doi. 10.1111/bjd.13473

By:

Takeichi, T.;
Nanda, A.;
Aristodemou, S.;
McMillan, J.R.;
Lee, J.;
Akiyama, M.;
Al‐Ajmi, H.;
Simpson, M.A.;
McGrath, J.A.

Publication type:

Article

Expression of matriptase correlates with tumour progression and clinical prognosis in oral squamous cell carcinoma.

Published in:

Histopathology, 2014, v. 65, n. 1, p. 24, doi. 10.1111/his.12361

By:

Cheng, Ming‐Fang;
Huang, Mao‐Suan;
Lin, Chun‐Shu;
Lin, Li‐Han;
Lee, Herng‐Sheng;
Jiang, Jhih‐Cheng;
Hsia, Kan‐Tai

Publication type:

Article

Roles of CUB and LDL receptor class A domain repeats of a transmembrane serine protease matriptase in its zymogen activation.

Published in:

Journal of Biochemistry, 2013, v. 153, n. 1, p. 51, doi. 10.1093/jb/mvs118

By:

Inouye, Kuniyo;
Tomoishi, Marie;
Yasumoto, Makoto;
Miyake, Yuka;
Kojima, Kenji;
Tsuzuki, Satoshi;
Fushiki, Tohru

Publication type:

Article

Hepatocyte growth factor activator inhibitor type 1 inhibits protease activity and proteolytic activation of human airway trypsin-like protease.

Published in:

Journal of Biochemistry, 2012, v. 151, n. 2, p. 179, doi. 10.1093/jb/mvr131

By:

Kato, Minoru;
Hashimoto, Tomio;
Shimomura, Takeshi;
Kataoka, Hiroaki;
Ohi, Hideyuki;
Kitamura, Naomi

Publication type:

Article

Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis.

Published in:

PLoS Genetics, 2019, v. 15, n. 01, p. 1, doi. 10.1371/journal.pgen.1007882

By:

Drees, Leonard;
Königsmann, Tatiana;
Jaspers, Martin H. J.;
Pflanz, Ralf;
Riedel, Dietmar;
Schuh, Reinhard

Publication type:

Article

Expression and prognostic value of matriptase in ovarian serous adenocarcinoma.

Published in:

Oncology Letters, 2017, v. 13, n. 3, p. 1741, doi. 10.3892/ol.2017.5600

By:

MEI JI;
SHUNSHUANG LI;
YA XIE;
ZHAO ZHAO;
WEIZHONG CHANG;
YUE LI;
XINGHAN CHENG;
ZHUO WANG

Publication type:

Article

Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0183507

By:

Tseng, Chun-Che;
Jia, Bailing;
Barndt, Robert;
Gu, Yayun;
Chen, Chien-Yu;
Tseng, I-Chu;
Su, Sheng-Fang;
Wang, Jehng-Kang;
Johnson, Michael D.;
Lin, Chen-Yong

Publication type:

Article

Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167894

By:

Su, Hui Chen;
Liang, Yan A.;
Lai, Ying-Jung J.;
Chiu, Yi-Lin;
Barndt, Robert B.;
Shiao, Frank;
Chang, Hsiang-Hua D.;
Lu, Dajun D.;
Huang, Nanxi;
Tseng, Chun-Che;
Wang, Jehng-Kang;
Lee, Ming-Shyue;
Johnson, Michael D.;
Huang, Shih-Ming;
Lin, Chen-Yong

Publication type:

Article

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction.

Published in:

British Journal of Haematology, 2015, v. 168, n. 6, p. 891, doi. 10.1111/bjh.13225

By:

Wallace, Daniel F.;
Secondes, Eriza S.;
Rishi, Gautam;
Ostini, Lesa;
McDonald, Cameron J.;
Lane, Steven W.;
Vu, Therese;
Hooper, John D.;
Velasco, Gloria;
Ramsay, Andrew J.;
Lopez‐Otin, Carlos;
Subramaniam, V. Nathan

Publication type:

Article

A novel mutation in the CUB sequence of matriptase-2 ( TMPRSS6) is implicated in iron-resistant iron deficiency anaemia - response to Jaspers et al.

Published in:

British Journal of Haematology, 2013, v. 160, n. 4, p. 566, doi. 10.1111/bjh.12145

By:

Roetto, Antonella;
Porto, Graça

Publication type:

Article

Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency-Associated Developmental Defects by Preventing Matriptase Activation.

Published in:

PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002937

By:

Szabo, Roman;
Sales, Katiuchia Uzzun;
Kosa, Peter;
Shylo, Natalia A.;
Godiksen, Sine;
Hansen, Karina K.;
Friis, Stine;
Gutkind, J. Silvio;
Vogel, Lotte K.;
Hummler, Edith;
Camerer, Eric;
Bugge, Thomas H.

Publication type:

Article

Matriptase is highly upregulated in chronic lymphocytic leukemia and promotes cancer cell invasion.

Published in:

Leukemia (08876924), 2013, v. 27, n. 5, p. 1191, doi. 10.1038/leu.2012.289

By:

Gao, L;
Liu, M;
Dong, N;
Jiang, Y;
Lin, C-Y;
Huang, M;
Wu, D;
Wu, Q

Publication type:

Article

Correction: Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.

Published in:

2018

By:

Lee, Shiao-Pieng;
Kao, Chen-Yu;
Chang, Shun-Cheng;
Chiu, Yi-Lin;
Chen, Yen-Ju;
Chen, Ming-Hsing G.;
Chang, Chun-Chia;
Lin, Yu-Wen;
Chiang, Chien-Ping;
Wang, Jehng- Kang;
Lin, Chen-Yong;
Johnson, Michael D.

Publication type:

Correction Notice

Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis.

Published in:

2017

By:

Chuan-Jin Wu;
Xu Feng;
Michael Lu;
Morimura, Sohshi;
Udey, Mark C.;
Wu, Chuan-Jin;
Feng, Xu;
Lu, Michael

Publication type:

journal article

Overexpression of matriptase correlates with poor prognosis in esophageal squamous cell carcinoma.

Published in:

Virchows Archiv: European Journal of Pathology, 2014, v. 464, n. 1, p. 19, doi. 10.1007/s00428-013-1504-3

By:

Ha, Sang;
Kim, Ki;
Lee, Nam;
Kim, Moon;
Kim, Seok-Hyung

Publication type:

Article

Changing the selectivity profile – from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 89, doi. 10.3109/14756366.2016.1172574

By:

Maiwald, Alexander;
Hammami, Maya;
Wagner, Sebastian;
Heine, Andreas;
Klebe, Gerhard;
Steinmetzer, Torsten

Publication type:

Article

Interaction exists between matriptase inhibitors and intestinal epithelial cells.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 736, doi. 10.3109/14756366.2015.1060483

By:

Pászti-Gere, Erzsebet;
Barna, Réka Fanni;
Ujhelyi, Gabriella;
Steinmetzer, Torsten

Publication type:

Article

Matriptase processing of APLP1 ectodomain alters its homodimerization.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67005-6

By:

Lanchec, Erwan;
Désilets, Antoine;
Béliveau, François;
Fontaine-Carbonneau, Cloé;
Laniel, Andréanne;
Leduc, Richard;
Lavoie, Christine

Publication type:

Article

Author Correction: The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.

Published in:

2020

By:

Wu, Shang-Ru;
Teng, Chen-Hsin;
Tu, Ya-Ting;
Ko, Chun-Jung;
Cheng, Tai-Shan;
Lan, Shao-Wei;
Lin, Hsin-Ying;
Lin, Hsin-Hsien;
Tu, Hsin-Fang;
Hsiao, Pei-Wen;
Huang, Hsiang-Po;
Chen, Chung-Hsin;
Lee, Ming-Shyue

Publication type:

Correction Notice

Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis.

Published in:

Oncogene, 2012, v. 31, n. 32, p. 3679, doi. 10.1038/onc.2011.545

By:

Kosa, P;
Szabo, R;
Molinolo, A A;
Bugge, T H

Publication type:

Article

Decreased Hemojuvelin Protein Levels in Mask Mice Lacking Matriptase-2-Dependent Proteolytic Activity.

Published in:

Physiological Research, 2013, v. 62, n. 4, p. 405, doi. 10.33549/physiolres.932455

By:

FRÝDLOVÁ, J.;
Y. FUJIKURA;
VOKURKA, M.;
NEČAS, E.;
KRIJT, J.

Publication type:

Article

The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.

Published in:

Biological Chemistry, 2016, v. 397, n. 8, p. 777, doi. 10.1515/hsz-2015-0263

By:

Beckmann, Anna-Madeleine;
Glebov, Konstantin;
Walter, Jochen;
Merkel, Olaf;
Mangold, Martin;
Schmidt, Frederike;
Becker-Pauly, Christoph;
Gütschow, Michael;
Stirnberg, Marit

Publication type:

Article

Cell surface serine protease matriptase-2 suppresses fetuin-A/AHSG-mediated induction of hepcidin.

Published in:

Biological Chemistry, 2015, v. 396, n. 1, p. 81, doi. 10.1515/hsz-2014-0120

By:

Stirnberg, Marit;
Maurer, Eva;
Arenz, Katharina;
Babler, Anne;
Jahnen-Dechent, Willi;
Gütschow, Michael

Publication type:

Article

Matriptase-2 (TMPRSS6) is directly up-regulated by hypoxia inducible factor-1: identification of a hypoxia-responsive element in the TMPRSS6 promoter region.

Published in:

Biological Chemistry, 2012, v. 393, n. 6, p. 535, doi. 10.1515/hsz-2011-0221

By:

Maurer, Eva;
Gütschow, Michael;
Stirnberg, Marit

Publication type:

Article

The matriptase-prostasin proteolytic cascade in epithelial development and pathology.

Published in:

Cell & Tissue Research, 2013, v. 351, n. 2, p. 245, doi. 10.1007/s00441-012-1348-1

By:

Miller, Gregory;
List, Karin

Publication type:

Article

Decreasing the ratio of matriptase/HAI-1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 2, p. 1465, doi. 10.3892/mmr.2016.5435

By:

PENGMING SUN;
ZHONGQING JIANG;
XIAOFANG CHEN;
LIFANG XUE;
XIAODAN MAO;
GUANYU RUAN;
YIYI SONG;
MUSTEA, ALEXANDER

Publication type:

Article

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0152904

By:

Lai, Chih-Hsin;
Lai, Ying-Jung J.;
Chou, Feng-Pai;
Chang, Hsiang-Hua D.;
Tseng, Chun-Che;
Johnson, Michael D.;
Wang, Jehng-Kang;
Lin, Chen-Yong

Publication type:

Article

Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148540

By:

Frýdlová, Jana;
Přikryl, Petr;
Truksa, Jaroslav;
Falke, Lucas L.;
Du, Xin;
Gurieva, Iuliia;
Vokurka, Martin;
Krijt, Jan

Publication type:

Article

Inhibition of Matriptase Activity Results in Decreased Intestinal Epithelial Monolayer Integrity In Vitro.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141077

By:

Pászti-Gere, E.;
McManus, S.;
Meggyesházi, N.;
Balla, P.;
Gálfi, P.;
Steinmetzer, T.

Publication type:

Article

N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132163

By:

Lai, Ying-Jung J.;
Chang, Hsiang-Hua D.;
Lai, Hongyu;
Xu, Yuan;
Shiao, Frank;
Huang, Nanxi;
Li, Linpei;
Lee, Ming-Shyue;
Johnson, Michael D.;
Wang, Jehng-Kang;
Lin, Chen-Yong

Publication type:

Article

Matriptase Autoactivation Is Tightly Regulated by the Cellular Chemical Environments.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093899

By:

Wang, Jehng-Kang;
Teng, I-Jou;
Lo, Ting-Jen;
Moore, Sean;
Yeo, Yee Hui;
Teng, Yun-Chung;
Kaul, Malvika;
Chen, Chiann-Chyi;
Zuo, Annie Hong;
Chou, Fen-Pai;
Yang, Xiaoyu;
Tseng, I-Chu;
Johnson, Michael D.;
Lin, Chen-Yong

Publication type:

Article

Human Cancer Cells Retain Modest Levels of Enzymatically Active Matriptase Only in Extracellular Milieu following Induction of Zymogen Activation.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092244

By:

Chu, Li-Ling;
Xu, Yuan;
Yang, Jie-Ru;
Hu, Yi-An;
Chang, Hsiang-Hua;
Lai, Hong-Yu;
Tseng, Chun-Che;
Wang, Hue-Yu;
Johnson, Michael D.;
Wang, Jehng-Kang;
Lin, Chen-Yong

Publication type:

Article

Matriptase Deletion Initiates a Sjögren’s Syndrome-Like Disease in Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0082852

By:

Yin, Hongen;
Kosa, Peter;
Liu, Xibao;
Swaim, William D.;
Lai, Zhennan;
Cabrera-Perez, Javier;
Di Pasquale, Giovanni;
Ambudkar, Indu S.;
Bugge, Thomas H.;
Chiorini, John A.

Publication type:

Article

Antithrombin Regulates Matriptase Activity Involved in Plasmin Generation, Syndecan Shedding, and HGF Activation in Keratinocytes

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062826

By:

Chen, Ya-Wen;
Xu, Zhenghong;
Baksh, Adrienne N. H.;
Wang, Jehng-Kang;
Chen, Chiu-Yuan;
Swanson, Richard;
Olson, Steve T.;
Kataoka, Hiroaki;
Johnson, Michael D.;
Lin, Chen-Yong

Publication type:

Article

Diversity of Matriptase Expression Level and Function in Breast Cancer.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034182

By:

Welman, Arkadiusz;
Sproul, Duncan;
Mullen, Peter;
Muir, Morwenna;
Kinnaird, Andrew R.;
Harrison, David J.;
Faratian, Dana;
Brunton, Valerie G.;
Frame, Margaret C.

Publication type:

Article

Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival.

Published in:

PLoS Genetics, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pgen.1004470

By:

Szabo, Roman;
Peters, Diane E.;
Kosa, Peter;
Camerer, Eric;
Bugge, Thomas H.

Publication type:

Article

Matriptase-2 inhibits HECV motility and tubule formation in vitro and tumour angiogenesis in vivo.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 375, n. 1/2, p. 207, doi. 10.1007/s11010-012-1544-z

By:

Webb, Siobhan;
Sanders, Andrew;
Mason, Malcolm;
Jiang, Wen

Publication type:

Article

The role of TMPRSS6/matriptase-2 in iron regulation and anemia.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00114

By:

Chia-Yu Wang;
Meynard, Delphine;
Lin, Herbert Y.;
Camaschella, Clara

Publication type:

Article

A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2.

Published in:

Pharmaceuticals (14248247), 2018, v. 11, n. 2, p. 49, doi. 10.3390/ph11020049

By:

Mangold, Martin;
Gütschow, Michael;
Stirnberg, Marit

Publication type:

Article

Matriptase Regulates Proliferation and Early, but Not Terminal, Differentiation of Human Keratinocytes.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 2, p. 405, doi. 10.1038/jid.2013.320

By:

Chen, Ya-Wen;
Wang, Jehng-Kang;
Chou, Fen-Pai;
Wu, Bai-Yao;
Hsiao, Hui-Chung;
Chiu, Han;
Xu, Zhonghong;
Baksh, Adrienne N.H.;
Shi, Galen;
Kaul, Malvika;
Barndt, Robert;
Shanmugam, Victoria K;
Johnson, Michael D;
Lin, Chen-Yong

Publication type:

Article

Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2.

Published in:

Biochemical Journal, 2013, v. 450, n. 3, p. 583, doi. 10.1042/BJ20121518

By:

MAURER, Eva;
GÜTSCHOW, Michael;
STIRNBERG, Marit

Publication type:

Article

From prediction to experimental validation: desmoglein 2 is a functionally relevant substrate of matriptase in epithelial cells and their reciprocal relationship is important for cell adhesion.

Published in:

Biochemical Journal, 2012, v. 447, n. 1, p. 61, doi. 10.1042/BJ20111432

By:

WADHAWAN, Vinita;
KOLHE, Yogesh A.;
SANGITH, Nikhil;
GAUTAM, Amit Kumar Singh;
VENKATRAMAN, Prasanna

Publication type:

Article

Recombinant hepatocyte growth factor activator inhibitor 1: expression in Drosophila S2 cells, purification and crystallization.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2017, v. 73, n. 1, p. 45, doi. 10.1107/S2053230X16020082

By:

Liu, Min;
Yuan, Cai;
Jiang, Yunbin;
Jiang, Longguang;
Huang, Mingdong

Publication type:

Article

Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors.

Published in:

Oncogene, 2015, v. 34, n. 35, p. 4664, doi. 10.1038/onc.2014.391

By:

Sales, K U;
Friis, S;
Abusleme, L;
Moutsopoulos, N M;
Bugge, T H

Publication type:

Article

Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis.

Published in:

Oncogene, 2015, v. 34, n. 3, p. 346, doi. 10.1038/onc.2013.563

By:

Sales, K U;
Friis, S;
Konkel, J E;
Godiksen, S;
Hatakeyama, M;
Hansen, K K;
Rogatto, S R;
Szabo, R;
Vogel, L K;
Chen, W;
Gutkind, J S;
Bugge, T H

Publication type:

Article

HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase.

Published in:

Oncogene, 2014, v. 33, n. 38, p. 4643, doi. 10.1038/onc.2013.412

By:

C-H Tsai;
C-H Teng;
Y-T Tu;
T-S Cheng;
S-R Wu;
C-J Ko;
H-Y Shyu;
S-W Lan;
H-P Huang;
S-F Tzeng;
MD Johnson;
C-Y Lin;
P-W Hsiao;
M-S Lee

Publication type:

Article

Spotlights on our sister journals: ChemCatChem 12/2016.

Published in:: ChemCatChem, 2016, v. 8, n. 12, p. 1994, doi. 10.1002/cctc.201681213
Publication type:: Article

Is the acronym IRIDA acceptable for slow responders to iron in the presence of TMPRSS6 mutations?

Published in:

Turkish Journal of Pediatrics, 2013, v. 55, n. 5, p. 479

By:

Yılmaz-Keskin, Ebru;
Sal, Ertan;
de Falco, Luigia;
Bruno, Mariasole;
Iolascon, Achille;
Koçak, Ülker;
Yenicesu, İdil

Publication type:

Article