Works matching DE "DNA topoisomerases"
Results: 489
Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn‐BNP)‐Coupled Metagenomics.
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- Angewandte Chemie, 2024, v. 136, n. 17, p. 1, doi. 10.1002/ange.202317187
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Pharmacokinetic scaling of SJ-8029, a novel anticancer agent possessing microtubule and topoisomerase inhibiting activities, by species-invariant time methods.
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- Biopharmaceutics & Drug Disposition, 2003, v. 24, n. 5, p. 191, doi. 10.1002/bdd.352
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An insight into the evolution of introns in the <italic>gyrase A</italic> gene of plants.
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- Plant Systematics & Evolution, 2018, v. 304, n. 4, p. 521, doi. 10.1007/s00606-018-1503-6
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TOPO6: a nuclear single-copy gene for plant phylogenetic inference.
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- Plant Systematics & Evolution, 2016, v. 302, n. 2, p. 239, doi. 10.1007/s00606-015-1259-1
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- Article
Introduction of pharmacophore groups into bis(indol-1-yl)maleimides and 6H-pyrrolo[3,4: 2,3][1,4]diazepino[6,7,1-hi]-indolo-8,10(7H,9H)-diones.
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- Pharmaceutical Chemistry Journal, 2006, v. 40, n. 8, p. 435, doi. 10.1007/s11094-006-0147-y
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Genome mining reveals uncommon alkylpyrones as type III PKS products from myxobacteria.
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- Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 3/4, p. 319, doi. 10.1007/s10295-018-2105-6
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175. INDUCTION OF ALTERNATIVE SPLICING BY DNA TOPO ISOMERASE POISONING IN HUMAN CELLS.
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- 2003
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- Abstract
Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition and apoptosis induction.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2302920
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DNA topoisomerases as molecular targets for anticancer drugs.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1781, doi. 10.1080/14756366.2020.1821676
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Topoisomerases inhibition and DNA binding mode of daunomycin–oligoarginine conjugate.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1363, doi. 10.1080/14756366.2020.1780226
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N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 434, doi. 10.1080/14756366.2017.1419216
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Topoisomerase as target for antibacterial and anticancer drug discovery.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 3, p. 419, doi. 10.3109/14756366.2012.658785
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- Article
Cytotoxic evaluation of sarcodifurines A and B, two novel dihydrofuroquinolines from Sarcomelicope follicularis (Rutaceae).
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2008, v. 23, n. 5, p. 704, doi. 10.1080/14756360802208111
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DNA topoisomerase inhibitory activity and 3D-QSAR analysis of benzazoles.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2016, v. 62, p. 535
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- Article
Alleviatory efficacy of achillea millefolium L. in etoxazole-mediated toxicity in allium cepa L.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81586-6
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Composition of Transcription Machinery and Its Crosstalk with Nucleoid-Associated Proteins and Global Transcription Factors.
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- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 924, doi. 10.3390/biom11070924
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Inhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer Therapy.
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- Biomolecules (2218-273X), 2015, v. 5, n. 3, p. 1652, doi. 10.3390/biom5031652
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- Article
Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives.
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- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00274
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- Article
Immunohistochemical analysis of p16INK4a, p14ARF, p18INK4c, p21CIP1, p27KIP1 and p73 expression in 271 meningiomas correlation with tumor grade and clinical outcome.
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- International Journal of Cancer, 2003, v. 104, n. 6, p. 728, doi. 10.1002/ijc.11013
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DNA Topoisomerases Beyond the standard role.
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- Transcription (2154-1264), 2013, v. 5, p. 1, doi. 10.4161/trns.26598
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DNA Topoisomerases.
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- Transcription (2154-1264), 2013, v. 4, n. 5, p. 1, doi. 10.4161/trns.26598
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The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity.
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- PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0215696
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In vitro Quinolones Susceptibility Analysis of Chinese Mycoplasma bovis Isolates and their Phylogenetic Scenarios based upon QRDRs of DNA Topoisomerases Revealing a Unique Transition in ParC.
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- Pakistan Veterinary Journal, 2013, v. 33, n. 3, p. 364
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Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani
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- FEBS Letters, 2004, v. 565, n. 1-3, p. 81, doi. 10.1016/j.febslet.2004.03.078
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Kinetic analysis of human topoisomerase IIα and β DNA binding by surface plasmon resonance
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- FEBS Letters, 2003, v. 554, n. 1/2, p. 206, doi. 10.1016/S0014-5793(03)01172-4
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The SUMO pathway is required for selective degradation of DNA topoisomerase IIβ induced by a catalytic inhibitor ICRF-193<sup>1</sup><FN ID="FN1"><NO>1</NO>The DT40 cell line used here (Ubc9<sup>−/−/−</sup>tetUbc9) will be available from RIKEN Cell Bank (http://www.rtc.riken.go.jp/CELL/HTML/RIKEN_Cell_Bank.html) by specifying the RCB number (RCB 1845) and the cell line name (delta Ubc9+cUbc9-DT40).</FN>
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- FEBS Letters, 2003, v. 546, n. 2/3, p. 374, doi. 10.1016/S0014-5793(03)00637-9
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Human topoisomerase II-α is highly expressed in sinonasal-inverted papilloma, but not in inflammatory polyp.
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- Journal of Cellular & Molecular Medicine, 2008, v. 12, n. 5a, p. 1551, doi. 10.1111/j.1582-4934.2008.00381.x
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In front of and behind the replication fork: bacterial type IIA topoisomerases.
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- Cellular & Molecular Life Sciences, 2010, v. 67, n. 12, p. 2001, doi. 10.1007/s00018-010-0299-5
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RecQ helicases and topoisomerases: components of a conserved complex for the regulation of genetic recombination.
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- Cellular & Molecular Life Sciences, 2001, v. 58, n. 7, p. 894, doi. 10.1007/PL00000909
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In vitro cross-resistance to nucleoside analogues and inhibitors of topoisomerase 1 and 2 in acute myeloid leukemia.
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- Annals of Hematology, 2008, v. 87, n. 1, p. 27, doi. 10.1007/s00277-007-0361-z
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Decatenation of DNA circles by FtsK-dependent Xer site-specific recombination.
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- EMBO Journal, 2003, v. 22, n. 23, p. 6399
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Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X a-satellite array.
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- EMBO Journal, 2002, v. 21, n. 19, p. 5269, doi. 10.1093/emboj/cdf511
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Multiple roles of Spo11 in meiotic chromosome behavior.
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- EMBO Journal, 2000, v. 19, n. 11, p. 2739, doi. 10.1093/emboj/19.11.2739
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Core histone N-termini play an essential role in mitotic chromosome condensation.
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- EMBO Journal, 2000, v. 19, n. 3, p. 379, doi. 10.1093/emboj/19.3.379
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The essential role of yeast topoisomerase III in meiosis depends on recombination.
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- EMBO Journal, 1999, v. 18, n. 6, p. 1701, doi. 10.1093/emboj/18.6.1701
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Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.
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- EMBO Journal, 1999, v. 18, n. 5, p. 1397, doi. 10.1093/emboj/18.5.1397
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Yeast telomeric sequences function as chromosomal anchorage points in vivo.
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- EMBO Journal, 1997, v. 16, n. 3, p. 523, doi. 10.1093/emboj/16.3.523
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Structure of NaeI?DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement.
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- Nature Structural Biology, 2001, v. 8, n. 8, p. 665, doi. 10.1038/90366
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A DNA acrobat.
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- Nature Structural Biology, 2001, v. 8, n. 7, p. 583, doi. 10.1038/89607
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Enzymes that push DNA around.
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- Nature Structural Biology, 1999, v. 6, n. 10, p. 900
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A Flp-nick system to study repair of a single protein-bound nick in vivo.
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- Nature Methods, 2009, v. 6, n. 10, p. 753, doi. 10.1038/nmeth.1372
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Topoisomerases I and III inhibit R-loop formation to prevent unregulated replication in the chromosomal Ter region of Escherichia coli.
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- PLoS Genetics, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.pgen.1007668
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The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates.
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- PLoS Genetics, 2018, v. 14, n. 9, p. 1, doi. 10.1371/journal.pgen.1007674
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Functional Expression of a DNA-Topoisomerase IB from Cryptosporidium parvum.
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- Journal of Biomedicine & Biotechnology, 2009, p. 1, doi. 10.1155/2009/837608
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Inhibition of DNA Topoisomerase II in Living Cells Stimulates Illegitimate Recombination.
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- Doklady Biochemistry & Biophysics, 2005, v. 405, n. 1-6, p. 423, doi. 10.1007/s10628-005-0130-7
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Human genome-derived TOP1 matrix attachment region enhances transgene expression in the transfected CHO cells.
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- Biotechnology Letters, 2019, v. 41, n. 6/7, p. 701, doi. 10.1007/s10529-019-02673-7
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Prediction of noncovalent Drug/DNA interaction using computational docking models: Studies with over 1350 launched drugs.
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- Environmental & Molecular Mutagenesis, 2013, v. 54, n. 8, p. 668, doi. 10.1002/em.21796
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Redox state alters anti-cancer effects of wedelolactone.
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- Environmental & Molecular Mutagenesis, 2012, v. 53, n. 7, p. 515, doi. 10.1002/em.21712
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Possible Structural and Functional Determinants Contributing to the Clastogenicity of Pharmaceuticals.
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- Environmental & Molecular Mutagenesis, 2010, v. 51, n. 8/9, p. 800, doi. 10.1002/em.20626
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First total synthesis of the (±)-2-methoxy-6-heptadecynoic acid and related 2-methoxylated analogs as effective inhibitors of the Leishmania topoisomerase IB enzyme.
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- Pure & Applied Chemistry, 2012, v. 84, n. 9, p. 1867, doi. 10.1351/PAC-CON-11-10-21
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