Works matching AU El-Azab, Adel S.

Results: 39

Antibacterial evaluation of 2-(6-Chloro-2-p-tolylquinazolin-4-ylthio) acetonitrile against pathogenic bacterial isolates with special reference to biofilm formation inhibition and anti-adherence properties.

Published in:

Journal of King Saud University - Science, 2024, v. 36, n. 8, p. N.PAG, doi. 10.1016/j.jksus.2024.103316

By:

Alasmari, Sultan Z.;
Makkawi, Mohammed H.;
Ahmad, Irfan;
Hakami, Abdulrahim R.;
Almehizia, Abdulrahman A.;
El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghazwani, Mohammed

Publication type:

Article

An Efficient Synthesis of Thioesters Via TFA-Catalyzed Reaction of Carboxylic Acid and Thiols: Remarkably Facile C–S Bond Formation.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2012, v. 187, n. 9, p. 1046, doi. 10.1080/10426507.2012.664220

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Synthesis of Some New Substituted 2-Mercaptoquinazoline Analogs as Potential Antimicrobial Agents.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2007, v. 182, n. 2, p. 333, doi. 10.1080/10426500600919207

By:

El-Azab, Adel S.

Publication type:

Article

Synthesis, Antitumor Activities, and Apoptosis-Inducing Activities of Schiff's Bases Incorporating Imidazolidine-2,4-dione Scaffold: Molecular Docking Studies and Enzymatic Inhibition Activities.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 4, p. 496, doi. 10.3390/ph18040496

By:

Alanazi, Fhdah S.;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Asiri, Hanadi H.;
Bakheit, Ahmed H.;
Al-Omary, Fatmah A.

Publication type:

Article

Crystal structure of 6-iodo-3-phenyl-2-propylquinazolin-4(3H)-one, C17H15IN2O.

Published in:

Zeitschrift für Kristallographie / New Crystal Structures, 2020, v. 235, n. 2, p. 489, doi. 10.1515/ncrs-2019-0788

By:

El-Azab, Adel S.;
Ghabbour, Hazem A.;
Abdel-Aziz, Alaa A.-M.;
Alkahtani, Hamad M.

Publication type:

Article

Crystal structure of (E)-N′-((4-aminophenyl)sulfonyl)-N,N-dimethylformimidamide, C9H13N3O2S.

Published in:

Zeitschrift für Kristallographie / New Crystal Structures, 2020, v. 235, n. 2, p. 483, doi. 10.1515/ncrs-2019-0781

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Ghabbour, Hazem A.;
Obaidullaha, Ahmad J.

Publication type:

Article

Hirshfeld Surface, Molecular Docking Study, Spectroscopic Characterization and NLO Profile of 2-Methoxy-4,6- Diphenylnicotinonitrile.

Published in:

ChemistrySelect, 2019, v. 4, n. 33, p. 9857, doi. 10.1002/slct.201902391

By:

Gökce, Halil;
Sert, Yusuf;
Alpaslan, Gökhan;
El-Azab, Adel S.;
Alanazi, Mohammed M.;
Al-Agamy, Mohamed H. M.;
Abdel-Aziz, Alaa A. -M.

Publication type:

Article

Structural, Spectroscopic, Electronic and Molecular Docking Studies on (11R,12 S)‐16‐Aminotetracyclo[6.6.2.02,7.09,14]hexadeca‐2(7),3,5,9(14),10,12‐hexaen‐15‐ol.

Published in:

ChemistrySelect, 2019, v. 4, n. 3, p. 825, doi. 10.1002/slct.201803732

By:

Kaya, Serdal;
Gökce, Halil;
El‐Azab, Adel S.;
Sert, Yusuf;
Alanazi, Mohammed M.;
Öztürk, Nuri;
Al‐Agamy, Mohamed H. M.;
Abdel‐Aziz, Alaa A.‐M.

Publication type:

Article

4‐[(1, 3‐Dioxoisoindolin‐2‐yl)methyl]benzenesulfonamide: Full Structural and Spectroscopic Characterization and Molecular Docking with Carbonic Anhydrase II.

Published in:

ChemistrySelect, 2018, v. 3, n. 35, p. 10113, doi. 10.1002/slct.201802484

By:

Gökce, Halil;
Öztürk, Nuri;
Sert, Yusuf;
El‐Azab, Adel S.;
A. AlSaif, Nawaf;
Abdel‐Aziz, Alaa A.‐M.

Publication type:

Article

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1487, doi. 10.1080/14756366.2021.1946044

By:

Fares, Salma;
Selim, Khalid B.;
Goda, Fatma E.;
El-Sayed, Magda A. A.;
AlSaif, Nawaf A.;
Hefnawy, Mohamed M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.

Publication type:

Article

Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1520, doi. 10.1080/14756366.2021.1924698

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
AlSaif, Nawaf A.;
Obaidullah, Ahmad J.;
Al-Obaid, Abdulrahman M.;
Al-Suwaidan, Ibrahim A.

Publication type:

Article

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 733, doi. 10.1080/14756366.2020.1742117

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Bua, Silvia;
Nocentini, Alessio;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
El-Gendy, Manal A.;
Ahmed, Hany E. A.;
Supuran, Claudiu T.

Publication type:

Article

Synthesis, antitumor activity, and molecular docking study of 2-cyclopentyloxyanisole derivatives: mechanistic study of enzyme inhibition.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 744, doi. 10.1080/14756366.2020.1740695

By:

El-Husseiny, Walaa M.;
El-Sayed, Magda A.-A.;
El-Azab, Adel S.;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 598, doi. 10.1080/14756366.2020.1722121

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ahmed, Hany E. A.;
Bua, Sivia;
Nocentini, Alessio;
AlSaif, Nawaf A.;
Obaidullah, Ahmad J.;
Hefnawy, Mohamed M.;
Supuran, Claudiu T.

Publication type:

Article

Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 610, doi. 10.1080/14756366.2020.1722120

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
AlSaif, Nawaf A.;
Alanazi, Mohammed M.;
El-Gendy, Manal A.;
Obaidullah, Ahmad J.;
Alkahtani, Hamad M.;
Almehizia, Abdulrahman A.;
Al-Suwaidan, Ibrahim A.

Publication type:

Article

Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 989, doi. 10.1080/14756366.2018.1474878

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Abou-Zeid, Laila A.;
El-Husseiny, Walaa M.;
El_Morsy, Ahmad M.;
El-Gendy, Manal A.;
El-Sayed, Magda A.-A.

Publication type:

Article

Synthesis, antitumour and antioxidant activities of novel α,β-unsaturated ketones and related heterocyclic analogues: EGFR inhibition and molecular modelling study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 507, doi. 10.1080/14756366.2018.1434519

By:

El-Husseiny, Walaa M.;
El-Sayed, Magda A.-A.;
Abdel-Aziz, Naglaa I.;
El-Azab, Adel S.;
Ahmed, Esam R.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 199, doi. 10.1080/14756366.2017.1407926

By:

El-Sayed, Magda A.-A.;
El-Husseiny, Walaa M.;
Abdel-Aziz, Naglaa I.;
El-Azab, Adel S.;
Abuelizz, Hatem A.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 1229, doi. 10.1080/14756366.2017.1368504

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
Al-Gendy, Manal A.

Publication type:

Article

Synthesis, anticancer and apoptosis-inducing activities of quinazoline–isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 935, doi. 10.1080/14756366.2017.1344981

By:

El-Azab, Adel S.;
Al-Dhfyan, Abdullah;
Abdel-Aziz, Alaa A.-M.;
Abou-Zeid, Laila A.;
Alkahtani, Hamad M.;
Al-Obaid, Abdulrahman M.;
Al-Gendy, Manal A.

Publication type:

Article

Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 796, doi. 10.3109/14756366.2015.1069288

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Alanazi, Amer M.;
Asiri, Yousif A.;
Al-Suwaidan, Ibrahim A.;
Maarouf, Azza R.;
Ayyad, Rezk R.;
Shawer, Taghreed Z.

Publication type:

Article

Synthesis, antitumor and antimicrobial activity of some new 6-methyl-3-phenyl-4(3 H )-quinazolinone analogues: in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 721, doi. 10.3109/14756366.2015.1060482

By:

Alanazi, Amer M.;
Abdel-Aziz, Alaa A.-M.;
Shawer, Taghreed Z.;
Ayyad, Rezk R.;
Al-Obaid, Abdulrahman M.;
Al-Agamy, Mohamed H. M.;
Maarouf, Azza R.;
El-Azab, Adel S.

Publication type:

Article

Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4(3H)quinazolinone analogues.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 1, p. 78, doi. 10.3109/14756366.2015.1004059

By:

Al-Suwaidan, Ibrahim A.;
Abdel-Aziz, Alaa A.-M.;
Shawer, Taghreed Z.;
Ayyad, Rezk R.;
Alanazi, Amer M.;
El-Morsy, Ahmad M.;
Mohamed, Menshawy A.;
Abdel-Aziz, Naglaa I.;
El-Sayed, Magda A.-A.;
El-Azab, Adel S.

Publication type:

Article

Antitumor evaluation and molecular docking study of substituted 2-benzylidenebutane-1,3-dione, 2-hydrazonobutane-1,3-dione and trifluoromethyl-1H-pyrazole analogues.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 4, p. 679, doi. 10.3109/14756366.2014.960863

By:

Al-Suwaidan, Ibrahim A.;
Abdel-Aziz, Naglaa I.;
El-Azab, Adel S.;
El-Sayed, Magda A.-A.;
Alanazi, Amer M.;
El-Ashmawy, Mahmoud B.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 1, p. 81, doi. 10.3109/14756366.2014.880696

By:

Abdel-Aziz, Alaa A-M.;
El-Azab, Adel S.;
Ekinci, Deniz;
Şentürk, Murat;
Supuran, Claudiu T.

Publication type:

Article

Crystal, molecular structure, and conformational preferences of 3-(2-(4-morpholinophenyl)-2-oxoethyl)-5,5-diphenylimidazolidine-2,4-dione.

Published in:

Molecular Crystals & Liquid Crystals, 2016, v. 631, n. 1, p. 144, doi. 10.1080/15421406.2016.1149027

By:

Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
El-Azab, Adel S.;
Khalil, Nasr Y.;
Fun, Hoong-Kun;
El-Sherbeny, Magda A.

Publication type:

Article

AMANTADINE AMIDES PRODRUGS AS HEPATIC DELIVERY SYSTEMS TO ENHANCE ITS ACTIVITY AGAINST HCV.

Published in:

Digest Journal of Nanomaterials & Biostructures (DJNB), 2011, v. 6, n. 4, p. 1675

By:

Aboul-Fadl, Tarek;
Sheha, Mahmoud M.;
El-Azab, Adel S.;
Abdel-Aziz, Hatem A.

Publication type:

Article

Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0212048

By:

Al-Shehri, Mona M.;
El-Azab, Adel S.;
El-Gendy, Manal A.;
Hamidaddin, Mohammed A.;
Darwish, Ibrahim A.

Publication type:

Article

Synthesis and Conformational Analysis of Sterically Congested (4R)-(--)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations.

Published in:

Journal of Chemistry, 2014, p. 1, doi. 10.1155/2014/173902

By:

Al-Swaidan, Ibrahim A.;
El-Azab, Adel S.;
Alanazi, Amer M.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

An Alternative Route for Synthesis of Chiral 4-Substituted 1-Arenesulfonyl-2-imidazolidinones: Unusual Utility of (4S,5S)- and (4R,5R)-4,5-Dimethoxy-2-imidazolidinones and X-Ray Crystallography.

Published in:

Journal of Chemistry, 2013, p. 1, doi. 10.1155/2013/349519

By:

Al-Swaidan, Ibrahim A.;
Alanazi, Amer M.;
El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

Antitumor Activity and Multi-Target Mechanism of Phenolic Schiff Bases Bearing Methanesulfonamide Fragments: Cell Cycle Analysis and a Molecular Modeling Study.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13621, doi. 10.3390/ijms252413621

By:

Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Brogi, Simone;
Ayyad, Rezk R.;
Al-Suwaidan, Ibrahim A.;
Hefnawy, Mohamed

Publication type:

Article

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography.

Published in:

Journal of Chemistry, 2021, p. 1, doi. 10.1155/2021/6612177

By:

El-Azab, Adel S.;
Khalil, Nasr Y.;
Abdel-Aziz, Alaa A.-M.

Publication type:

Article

A Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of the Dopamine Receptor Antagonist LE300 and Its N-methyl Metabolite in Plasma: Application to a Pharmacokinetic Study.

Published in:

Molecules, 2023, v. 28, n. 4, p. 1553, doi. 10.3390/molecules28041553

By:

Hefnawy, Mohamed M.;
Attwa, Mohamed W.;
Alzamil, Adeeba A.;
El-Gendy, Manal A.;
El-Azab, Adel S.;
Jardan, Yousef A. Bin;
El-Gamal, Ali A.

Publication type:

Article

Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 1, p. 120, doi. 10.3390/molecules28010120

By:

Alkahtani, Hamad M.;
Zen, Amer Alhaj;
Obaidullah, Ahmad J.;
Alanazi, Mohammed M.;
Almehizia, Abdulrahman A.;
Ansari, Siddique Akber;
Aleanizy, Fadilah Sfouq;
Alqahtani, Fulwah Yahya;
Aldossari, Rana M.;
Algamdi, Raghad Abdullah;
Al-Rasheed, Lamees S.;
Abdel-Hamided, Sami G.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.

Publication type:

Article

A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma—Application to a Pharmacokinetic Study

Published in:

Molecules, 2023, v. 28, n. 1, p. 79, doi. 10.3390/molecules28010079

By:

Hefnawy, Mohamed M.;
Alanazi, Mohammed M.;
Al-Hossaini, Abdullah M.;
Alnasser, Abdulaziz I.;
El-Azab, Adel S.;
Jardan, Yousef A. Bin;
Attwa, Mohamed W.;
El-Gendy, Manal A.

Publication type:

Article

Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.

Published in:

Molecules, 2022, v. 27, n. 22, p. 7703, doi. 10.3390/molecules27227703

By:

El-Azab, Adel S.;
Abdel-Aziz, Alaa A.-M.;
Ghabbour, Hazem A.;
Bua, Silvia;
Nocentini, Alessio;
Alkahtani, Hamad M.;
Alsaif, Nawaf A.;
Al-Agamy, Mohamed H. M.;
Supuran, Claudiu T.

Publication type:

Article

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin.

Published in:

Molecules, 2022, v. 27, n. 1, p. 90, doi. 10.3390/molecules27010090

By:

Abdalla, Ashraf N.;
Di Stefano, Miriana;
Poli, Giulio;
Tuccinardi, Tiziano;
Bader, Ammar;
Vassallo, Antonio;
Abdallah, Mohamed E.;
El-Readi, Mahmoud Zaki;
Refaat, Bassem;
Algarni, Alanood S.;
Ahmad, Rizwan;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Alqathama, Aljawharah

Publication type:

Article

Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies.

Published in:

Molecules, 2021, v. 26, n. 10, p. 2992, doi. 10.3390/molecules26102992

By:

Altamimi, Abdulmalik S.;
El-Azab, Adel S.;
Abdelhamid, Sami G.;
Alamri, Mubarak A.;
Bayoumi, Ashraf H.;
Alqahtani, Safar M.;
Alabbas, Alhumaidi B.;
Altharawi, Ali I.;
Alossaimi, Manal A.;
Mohamed, Menshawy A.;
Gauld, James

Publication type:

Article

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2220, doi. 10.3390/molecules25092220

By:

Abdalla, Ashraf N.;
Abdallah, Mohamed E.;
Aslam, Akhmed;
Bader, Ammar;
Vassallo, Antonio;
Tommasi, Nunziatina De;
Malki, Waleed H.;
Gouda, Ahmed M.;
Mukhtar, Mohammed H.;
El-Readi, Mahmoud Zaki;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Tylkowski, Bartosz;
Bajek, Anna;
Roszkowski, Krzysztof

Publication type:

Article

Works matching AU El-Azab, Adel S.

Antibacterial evaluation of 2-(6-Chloro-2-p-tolylquinazolin-4-ylthio) acetonitrile against pathogenic bacterial isolates with special reference to biofilm formation inhibition and anti-adherence properties.

An Efficient Synthesis of Thioesters Via TFA-Catalyzed Reaction of Carboxylic Acid and Thiols: Remarkably Facile C–S Bond Formation.

Synthesis of Some New Substituted 2-Mercaptoquinazoline Analogs as Potential Antimicrobial Agents.

Synthesis, Antitumor Activities, and Apoptosis-Inducing Activities of Schiff's Bases Incorporating Imidazolidine-2,4-dione Scaffold: Molecular Docking Studies and Enzymatic Inhibition Activities.

Crystal structure of 6-iodo-3-phenyl-2-propylquinazolin-4(3H)-one, C<sub>17</sub>H<sub>15</sub>IN<sub>2</sub>O.

Crystal structure of (E)-N′-((4-aminophenyl)sulfonyl)-N,N-dimethylformimidamide, C<sub>9</sub>H<sub>13</sub>N<sub>3</sub>O<sub>2</sub>S.

Hirshfeld Surface, Molecular Docking Study, Spectroscopic Characterization and NLO Profile of 2-Methoxy-4,6- Diphenylnicotinonitrile.

Structural, Spectroscopic, Electronic and Molecular Docking Studies on (11R,12 S)‐16‐Aminotetracyclo[6.6.2.0<sup>2,7</sup>.0<sup>9,14</sup>]hexadeca‐2(7),3,5,9(14),10,12‐hexaen‐15‐ol.

4‐[(1, 3‐Dioxoisoindolin‐2‐yl)methyl]benzenesulfonamide: Full Structural and Spectroscopic Characterization and Molecular Docking with Carbonic Anhydrase II.

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study.

Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study.

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.

Synthesis, antitumor activity, and molecular docking study of 2-cyclopentyloxyanisole derivatives: mechanistic study of enzyme inhibition.

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors.

Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study.

Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies.

Synthesis, antitumour and antioxidant activities of novel α,β-unsaturated ketones and related heterocyclic analogues: EGFR inhibition and molecular modelling study.

Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study.

Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues.

Synthesis, anticancer and apoptosis-inducing activities of quinazoline–isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies.

Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.

Synthesis, antitumor and antimicrobial activity of some new 6-methyl-3-phenyl-4(3 H )-quinazolinone analogues: in silico studies.

Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4(3H)quinazolinone analogues.

Antitumor evaluation and molecular docking study of substituted 2-benzylidenebutane-1,3-dione, 2-hydrazonobutane-1,3-dione and trifluoromethyl-1H-pyrazole analogues.

Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors.

Crystal, molecular structure, and conformational preferences of 3-(2-(4-morpholinophenyl)-2-oxoethyl)-5,5-diphenylimidazolidine-2,4-dione.

AMANTADINE AMIDES PRODRUGS AS HEPATIC DELIVERY SYSTEMS TO ENHANCE ITS ACTIVITY AGAINST HCV.

Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib.

Synthesis and Conformational Analysis of Sterically Congested (4R)-(--)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations.

An Alternative Route for Synthesis of Chiral 4-Substituted 1-Arenesulfonyl-2-imidazolidinones: Unusual Utility of (4S,5S)- and (4R,5R)-4,5-Dimethoxy-2-imidazolidinones and X-Ray Crystallography.

Antitumor Activity and Multi-Target Mechanism of Phenolic Schiff Bases Bearing Methanesulfonamide Fragments: Cell Cycle Analysis and a Molecular Modeling Study.

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography.

A Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of the Dopamine Receptor Antagonist LE300 and Its N-methyl Metabolite in Plasma: Application to a Pharmacokinetic Study.

Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors.

A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma—Application to a Pharmacokinetic Study

Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin.

Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies.

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.