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Results: 28

An Aryl Hydrocarbon Receptor Odyssey to the Shores of Toxicology: The Deichmann Lecture, International Congress of Toxicology-XI.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 5, doi. 10.1093/toxsci/kfm096
Publication type:
Article
Tesaglitazar, a PPAR{alpha}/{gamma} Agonist, Induces Interstitial Mesenchymal Cell DNA Synthesis and Fibrosarcomas in Subcutaneous Tissues in Rats.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 63, doi. 10.1093/toxsci/kfm094
By:
- Heike Hellmold;
- Hui Zhang;
- Ulf Andersson;
- Bo Blomgren;
- Tom Holland;
- Anna-Lena Berg;
- Marie Elebring;
- Niclas Sjögren;
- Krister Bamberg;
- Björn Dahl;
- Rolf Westerberg;
- Birgitta Dillner;
- Jonathan Tugwood;
- Ruth Roberts;
- Erik Lundholm;
- German Camejo;
- Inger Skånberg;
- John Evans
Publication type:
Article
Persistent Binding of Ligands to the Aryl Hydrocarbon Receptor.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 99
By:
- Jessica E. Bohonowych;
- Michael S. Denison
Publication type:
Article
Predicting Age-Appropriate Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically Based Pharmacokinetic Modeling.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 43, doi. 10.1093/toxsci/kfm082
By:
- Chester E. Rodriguez;
- Deirdre A. Mahle;
- Jeff M. Gearhart;
- David R. Mattie;
- John C. Lipscomb;
- Robert S. Cook;
- Hugh A. Barton
Publication type:
Article
Dysgenesis and Histological Changes of Genitals and Perturbations of Gene Expression in Male Rats after In Utero Exposure to Antiandrogen Mixtures.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 87
By:
- Stine Broeng Metzdorff;
- Majken Dalgaard;
- Sofie Christiansen;
- Marta Axelstad;
- Ulla Hass;
- Maria Kristina Kiersgaard;
- Martin Scholze;
- Andreas Kortenkamp;
- Anne Marie Vinggaard
Publication type:
Article
Arsenic as an Endocrine Disruptor: Effects of Arsenic on Estrogen Receptor-Mediated Gene Expression In Vivo and in Cell Culture.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 75, doi. 10.1093/toxsci/kfm013
By:
- Jennifer C. Davey;
- Jack E. Bodwell;
- Julie A. Gosse;
- Joshua W. Hamilton
Publication type:
Article
Elevation of 8-Hydroxydeoxyguanosine in DNA from Isolated Mouse Lung Cells Following In Vivo Treatment with Aflatoxin B1.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 57, doi. 10.1093/toxsci/kfm073
By:
- Katherine A. Guindon;
- Leanne L. Bedard;
- Thomas E. Massey
Publication type:
Article
Uniform Procedure of 1H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 286, doi. 10.1093/toxsci/kfm077
By:
- Willem G. E. J. Schoonen;
- Cathelijne P. A. M. Kloks;
- Jan-Peter H. T. M. Ploemen;
- Martin J. Smit;
- Pieter Zandberg;
- G. Jean Horbach;
- Jan-Remt Mellema;
- Carol Thijssen-vanZuylen;
- Albert C. Tas;
- Joop H. J. van Nesselrooij;
- Jack T. W. E. Vogels
Publication type:
Article
Migration of Intradermally Injected Quantum Dots to Sentinel Organs in Mice.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 249, doi. 10.1093/toxsci/kfm074
By:
- Neera V. Gopee;
- Dean W. Roberts;
- Peggy Webb;
- Christy R. Cozart;
- Paul H. Siitonen;
- Alan R. Warbritton;
- William W. Yu;
- Vicki L. Colvin;
- Nigel J. Walker;
- Paul C. Howard
Publication type:
Article
Rodent Carcinogenicity Profile of the Antidiabetic Dual PPAR {alpha} and {gamma} Agonist Muraglitazar.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 258, doi. 10.1093/toxsci/kfm083
By:
- Sarah H. Tannehill-Gregg;
- Thomas P. Sanderson;
- Daniel Minnema;
- Richard Voelker;
- Borge Ulland;
- Samuel M. Cohen;
- Lora L. Arnold;
- Beth E. Schilling;
- C. Robbie Waites;
- Mark A. Dominick
Publication type:
Article
Protection against Chromium (VI)-Induced Oxidative Stress and Apoptosis by Nrf2. Recruiting Nrf2 into the Nucleus and Disrupting the Nuclear Nrf2/Keap1 Association.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 298
By:
- Xiaoqing He;
- Gary X. Lin;
- Michael G. Chen;
- Jennifer X. Zhang;
- Qiang Ma
Publication type:
Article
Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part IV: A Strategy in Genotoxicity Testing in Drug Development: Some Examples.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 39, doi. 10.1093/toxsci/kfm056
By:
- Elisabeth Lorge;
- Véronique Gervais;
- Nathalie Becourt-Lhote;
- Catherine Maisonneuve;
- Jean-Luc Delongeas;
- Nancy Claude
Publication type:
Article
Sensitivity of 1H NMR Analysis of Rat Urine in Relation to Toxicometabonomics. Part I: Dose-Dependent Toxic Effects of Bromobenzene and Paracetamol.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 271
By:
- Willem G. E. J. Schoonen;
- Cathelijne P. A. M. Kloks;
- Jan-Peter H. T. M. Ploemen;
- G. Jean Horbach;
- Martin J. Smit;
- Pieter Zandberg;
- Jan-Remt Mellema;
- Carol Thijssen-van Zuylen;
- Albert C. Tas;
- Joop H. J. van Nesselrooij;
- Jack T. W. E. Vogels
Publication type:
Article
A Method to Integrate Benchmark Dose Estimates with Genomic Data to Assess the Functional Effects of Chemical Exposure.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 240, doi. 10.1093/toxsci/kfm092
By:
- Russell S. Thomas;
- Bruce C. Allen;
- Andy Nong;
- Longlong Yang;
- Edilberto Bermudez;
- Harvey J. Clewell;
- Melvin E. Andersen
Publication type:
Article
Alterations in Gene Expression and Testosterone Synthesis in the Testes of Male Rats Exposed to Perfluorododecanoic Acid.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 206, doi. 10.1093/toxsci/kfm070
By:
- Zhimin Shi;
- Hongxia Zhang;
- Yang Liu;
- Muqi Xu;
- Jiayin Dai
Publication type:
Article
Manganese Induces Oxidative Impairment in Cultured Rat Astrocytes.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 198, doi. 10.1093/toxsci/kfm095
By:
- Dejan Milatovic;
- Zhaobao Yin;
- Ramesh C. Gupta;
- Marta Sidoryk;
- Jan Albrecht;
- Judy L. Aschner;
- Michael Aschner
Publication type:
Article
Systemic Translocation of Particulate Matter-Associated Metals Following a Single Intratracheal Instillation in Rats.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 231, doi. 10.1093/toxsci/kfm088
By:
- J. Grace Wallenborn;
- John K. McGee;
- Mette C. Schladweiler;
- Allen D. Ledbetter;
- Urmila P. Kodavanti
Publication type:
Article
Cyclophosphamide-Induced Apoptosis in COV434 Human Granulosa Cells Involves Oxidative Stress and Glutathione Depletion.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 216, doi. 10.1093/toxsci/kfm087
By:
- Miyun Tsai-Turton;
- Brian T. Luong;
- Youming Tan;
- Ulrike Luderer
Publication type:
Article
Polybrominated Diphenyl Ethers and ortho-Substituted Polychlorinated Biphenyls as Neuroendocrine Disruptors of Vasopressin Release: Effects during Physiological Activation In Vitro and Structure-Activity Relationships.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 178, doi. 10.1093/toxsci/kfm086
By:
- Cary G. Coburn;
- Margarita C. Currás-Collazo;
- Prasada Rao S. Kodavanti
Publication type:
Article
Adult Hippocampal Neural Stem/Progenitor Cells In Vitro Are Vulnerable to the Mycotoxin Ochratoxin-A.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 187, doi. 10.1093/toxsci/kfm093
By:
- Vasyl Sava;
- Adriana Velasquez;
- Shijie Song;
- Juan Sanchez-Ramos
Publication type:
Article
Evaluating the NMDA-Glutamate Receptor as a Site of Action for Toluene, In Vivo.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 159, doi. 10.1093/toxsci/kfm080
By:
- Ambuja S. Bale;
- Meredith D. Jackson;
- Quentin Todd Krantz;
- Vernon A. Benignus;
- Philip J. Bushnell;
- Timothy J. Shafer;
- William K. Boyes
Publication type:
Article
Styrene Induced Alterations in Biomarkers of Exposure and Effects in the Cochlea: Mechanisms of Hearing Loss.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 167, doi. 10.1093/toxsci/kfm078
By:
- Guang-Di Chen;
- Lai-Har Chi;
- Paul J. Kostyniak;
- Donald Henderson
Publication type:
Article
Effects of Low Concentrations of Arsenic on the Innate Immune System of the Zebrafish (Danio Rerio).
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 118, doi. 10.1093/toxsci/kfm072
By:
- Akshata S. Nayak;
- Christopher R. Lage;
- Carol H. Kim
Publication type:
Article
An L-Tyrosine Derivative and PPAR{gamma} Agonist, GW7845, Activates a Multifaceted Caspase Cascade in Bone Marrow B Cells.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 125
By:
- Jennifer J. Schlezinger;
- Jessica K. Emberley;
- Stephanie L. Bissonnette;
- David H. Sherr
Publication type:
Article
Arsenic: Extension of its Endocrine Disruption Potential to Interference with Estrogen Receptor-Mediated Signaling.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 1, doi. 10.1093/toxsci/kfm111
By:
- Walter H. Watson;
- James D. Yager
Publication type:
Article
Comparison of Estimated Dietary Intake of Acrylamide with Hemoglobin Adducts of Acrylamide and Glycidamide.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 110, doi. 10.1093/toxsci/kfm091
By:
- Thomas Bjellaas;
- Pelle T. Olesen;
- Henrik Frandsen;
- Margaretha Haugen;
- Linn H. Stølen;
- Jan E. Paulsen;
- Jan Alexander;
- Elsa Lundanes;
- Georg Becher
Publication type:
Article
Ketamine-Induced Neuronal Cell Death in the Perinatal Rhesus Monkey.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 145, doi. 10.1093/toxsci/kfm084
By:
- William Slikker;
- Xiaoju Zou;
- Charlotte E. Hotchkiss;
- Rebecca L. Divine;
- Natalya Sadovova;
- Nathan C. Twaddle;
- Daniel R. Doerge;
- Andrew C. Scallet;
- Tucker A. Patterson;
- Joseph P. Hanig;
- Merle G. Paule;
- Cheng Wang
Publication type:
Article
Microsomal Expoxide Hydrolase Is Required for 7,12-Dimethylbenz[a]anthracene (DMBA)-Induced Immunotoxicity in Mice.
Published in:
Toxicological Sciences, 2007, v. 98, n. 1, p. 137, doi. 10.1093/toxsci/kfm089
By:
- Jun Gao;
- Fredine T. Lauer;
- Leah A. Mitchell;
- Scott W. Burchiel
Publication type:
Article