Works matching AU Varmus, Harold

Results: 52

Progress toward Public Access to Science.

Published in:

PLoS Biology, 2008, v. 6, n. 4, p. e101, doi. 10.1371/journal.pbio.0060101

By:

Varmus, Harold

Publication type:

Article

Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion.

Published in:

PLoS Biology, 2007, v. 5, n. 10, p. e276, doi. 10.1371/journal.pbio.0050276

By:

Yi-Chieh Nancy Du;
Lewis, Brian C.;
Hanahan, Douglas;
Varmus, Harold

Publication type:

Article

Three decades of Wnts: a personal perspective on how a scientific field developed.

Published in:

EMBO Journal, 2012, v. 31, n. 12, p. 2670, doi. 10.1038/emboj.2012.146

By:

Nusse, Roel;
Varmus, Harold

Publication type:

Article

FGF-20 and DKK1 are transcriptional targets ofß-catenin and FGF-20 is implicated in cancer and development.

Published in:

EMBO Journal, 2005, v. 24, n. 1, p. 73, doi. 10.1038/sj.emboj.7600460

By:

Chamorro, Mario N.;
Schwartz, Donald R.;
Vonica, Alin;
Brivanlou, Ali H.;
Cho, Kathleen R.;
Varmus, Harold E.

Publication type:

Article

The Challenge of Making Laws on the Shifting Terrain of Science.

Published in:

Journal of Law, Medicine & Ethics, 2000, v. 28, n. 4, p. 46

By:

Varmus, Harold E.

Publication type:

Article

Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.

Published in:

BMC Immunology, 2001, v. 2, p. 3, doi. 10.1186/1471-2172-2-3

By:

Chamorro, Mario;
Czar, Michael J.;
Debnath, Jayanta;
Genhong Cheng;
Lenardo, Michael J.;
Varmus, Harold E.;
Schwartzberg, Pamela L.

Publication type:

Article

THE ORIGIN AND STRUCTURE OF ENDOGENOUS RETROVIRAL DNA.

Published in:

Annals of the New York Academy of Sciences, 1980, v. 354, n. 1, p. 379, doi. 10.1111/j.1749-6632.1980.tb27979.x

By:

Varmus, Harold E.;
Cohen, J. Craig;
Hughes, Stephen H.;
Majors, John;
Bishop, J. Michael

Publication type:

Article

Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain.

Published in:

PLoS Medicine, 2005, v. 2, n. 3, p. 225, doi. 10.1371/journal.pmed.0020073

By:

Pao, William;
Miller, Vincent A.;
Politi, Katerina A.;
Riely, Gregory J.;
Somwar, Romel;
Zakowski, Maureen F.;
Kris, Mark G.;
Varmus, Harold

Publication type:

Article

KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib.

Published in:

PLoS Medicine, 2005, v. 2, n. 1, p. 57, doi. 10.1371/journal.pmed.0020017

By:

Pao, William;
Wang, Theresa Y.;
Riely, Gregory J.;
Miller, Vincent A.;
Qiulu Pan;
Ladanyi, Marc;
Zakowski, Maureen F.;
Heelan, Robert T.;
Kris, Mark G.;
Varmus, Harold E.

Publication type:

Article

PLoS Medicine-- A Medical Journal for the Internet Age.

Published in:

PLoS Medicine, 2004, v. 1, n. 1, p. 002, doi. 10.1371/journal.pmed.0010031

By:

Eisen, Michael B.;
Brown, Patrick O.;
Varmus, Harold E.

Publication type:

Article

Science funding: Provocative questions in cancer research.

Published in:

2012

By:

Varmus, Harold;
Harlow, Ed

Publication type:

Opinion

Winning the arguments on Capitol Hill.

Published in:

2009

By:

Varmus, Harold

Publication type:

Book Review

Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus.

Published in:

Nature, 1975, v. 253, n. 5492, p. 507, doi. 10.1038/253507a0

By:

Guntaka, Ramareddy V.;
Mahy, Brian W. J.;
Bishop, J. Michael;
Varmus, Harold E.

Publication type:

Article

A comparative evaluation of β-catenin and plakoglobin signaling activity.

Published in:

Oncogene, 2000, v. 19, n. 50, p. 5720, doi. 10.1038/sj.onc.1203921

By:

Williams, Bart O;
Barish, Grant D;
Klymkowsky, Michael W;
Varmus, Harold E

Publication type:

Article

Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer.

Published in:

Oncogene, 2000, v. 19, n. 8, p. 1002, doi. 10.1038/sj.onc.1203273

By:

Li, Yi;
Hively, Wendy P;
Varmus, Harold E

Publication type:

Article

Development of a flexible and specific gene delivery system for production of murine tumor models.

Published in:

Oncogene, 1999, v. 18, n. 38, p. 5253, doi. 10.1038/sj.onc.1203087

By:

Fisher, Galen H;
Orsulic, Sandra;
Holland, Eric;
Hively, Wendy P;
Li, Yi;
Lewis, Brian C;
Williams, Bart O;
Varmus, Harold E

Publication type:

Article

Epstein-Barr Virus: An Important Vaccine Target for Cancer Prevention.

Published in:

Science Translational Medicine, 2011, v. 3, n. 107, p. 1, doi. 10.1126/scitranslmed.3002878

By:

Cohen, Jeffrey I.;
Fauci, Anthony S.;
Varmus, Harold;
Nabel, Gary J.

Publication type:

Article

Integrating Cancer Control into Global Health.

Published in:

Science Translational Medicine, 2011, v. 3, n. 101, p. 1, doi. 10.1126/scitranslmed.3002321

By:

Varmus, Harold;
Trimble, Edward L.

Publication type:

Article

Genomic empowerment: the importance of public databases.

Published in:

Nature Genetics, 2003, v. 35, p. 3, doi. 10.1038/ng1186

By:

Varmus, Harold

Publication type:

Article

Genomic empowerment: the importance of public databases.

Published in:

Nature Genetics, 2002, v. 32, p. 3, doi. 10.1038/ng963

By:

Varmus, Harold

Publication type:

Article

Some Characteristics of Binding of Vitamin B12 by Normal Human Serum.

Published in:

Acta Haematologica, 1960, v. 23, n. 5, p. 287, doi. 10.1159/000206249

By:

Bertcher, Robert W.;
Meyer, Leo M.;
Varmus, Harold;
Mulzac, Claire

Publication type:

Article

Retroviruses and Oncogenes I (Nobel Lecture).

Published in:

Angewandte Chemie International Edition, 1990, v. 29, n. 7, p. 707, doi. 10.1002/anie.199007073

By:

Varmus, Harold E.

Publication type:

Article

The National Institutes of Health and clinical research: a progress report.

Published in:

Nature Medicine, 2000, v. 6, n. 11, p. 1201, doi. 10.1038/81282

By:

Nathan, David G.;
Varmus, Harold E.

Publication type:

Article

A protein knockdown strategy to study the function of β-catenin in tumorigenesis.

Published in:

BMC Molecular Biology, 2003, v. 4, p. 10, doi. 10.1186/1471-2199-4-10

By:

Feng Cong;
Jianxuan Zhang;
Pao, William;
Pengbo Zhou;
Varmus, Harold

Publication type:

Article

Deficiency of Pten accelerates mammary oncogenesis in MMTVWnt-1 transgenic mice.

Published in:

BMC Molecular Biology, 2001, v. 2, p. 1

By:

Yi Li;
Podsypanina, Podsy;
Xiufan Liu;
Crane, Allison;
Tan, Lee K.;
Parsons, Ramon;
Varmus, Harold E.

Publication type:

Article

Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors.

Published in:

BMC Cell Biology, 2003, v. 4, p. 4, doi. 10.1186/1471-2121-4-4

By:

Schweizer, Liang;
Varmus, Harold

Publication type:

Article

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.

Published in:

PLoS Genetics, 2016, v. 12, n. 10, p. 1, doi. 10.1371/journal.pgen.1006384

By:

Fei, Dennis Liang;
Motowski, Hayley;
Chatrikhi, Rakesh;
Prasad, Sameer;
Yu, Jovian;
Gao, Shaojian;
Kielkopf, Clara L.;
Bradley, Robert K.;
Varmus, Harold

Publication type:

Article

Why PLoS Became a Publisher.

Published in:

PLoS Biology, 2003, v. 1, n. 10, p. 1, doi. 10.1371/journal.pbio.0000036

By:

Brown, Patrick O;
Eisen, Michael B;
Varmus, Harold E

Publication type:

Article

Why PLoS Became a Publisher.

Published in:

PLoS Biology, 2003, v. 1, n. 1, p. 1, doi. 10.1371/journal.pbio.0000036

By:

Brown, Patrick O.;
Elsen, Michael B.;
Varmus, Harold E.

Publication type:

Article

Alfred P. Sloan prize. Viruses, genes, and cancer. I. The discovery of cellular oncogenes and their role in neoplasia.

Published in:

Cancer (0008543X), 1985, v. 55, n. 10, p. 2324, doi. 10.1002/1097-0142(19850515)55:10<2324::AID-CNCR2820551004>3.0.CO;2-A

By:

Varmus, Harold E.

Publication type:

Article

Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture.

Published in:

Nature, 1985, v. 316, n. 6024, p. 160, doi. 10.1038/316160a0

By:

Schwab, Manfred;
Varmus, Harold E.;
Bishop, J. Michael

Publication type:

Article

Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells.

Published in:

Nature, 1985, v. 315, n. 6017, p. 345, doi. 10.1038/315345a0

By:

Schwab, Manfred;
Ramsay, Gary;
Alitalo, Kari;
Varmus, Harold E.;
Bishop, J. Michael;
Martinsson, Tommy;
Levan, Goran;
Levan, Albert

Publication type:

Article

Molecular biology: Reverse transcriptase rides again.

Published in:

Nature, 1985, v. 314, n. 6012, p. 583, doi. 10.1038/314583a0

By:

Varmus, Harold E.

Publication type:

Article

Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc.

Published in:

Nature, 1984, v. 308, n. 5956, p. 288, doi. 10.1038/308288a0

By:

Schwab, Manfred;
Varmus, Harold E.;
Bishop, J. Michael;
Grzeschik, Karl-Heinz;
Naylor, Susan L.;
Sakaguchi, Alan Y.;
Brodeur, Garrett;
Trent, Jeffrey

Publication type:

Article

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15.

Published in:

Nature, 1984, v. 307, n. 5947, p. 131, doi. 10.1038/307131a0

By:

Nusse, Roel;
van Ooyen, Albert;
Cox, David;
Fung, Yuen Kai T.;
Varmus, Harold

Publication type:

Article

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.

Published in:

Nature, 1983, v. 305, n. 5931, p. 245, doi. 10.1038/305245a0

By:

Schwab, Manfred;
Alitalo, Kari;
Klempnauer, Karl-Heinz;
Varmus, Harold E.;
Bishop, J. Michael;
Gilbert, Fred;
Brodeur, Garrett;
Goldstein, Milton;
Trent, Jeffrey

Publication type:

Article

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas.

Published in:

Nature, 1982, v. 295, n. 5846, p. 209, doi. 10.1038/295209a0

By:

Payne, Gregory S.;
Bishop, J. Michael;
Varmus, Harold E.

Publication type:

Article

Addressing the Growing International Challenge of Cancer: A Multinational Perspective.

Published in:

Science Translational Medicine, 2013, v. 5, n. 175, p. 1, doi. 10.1126/scitranslmed.3005899

By:

Varmus, Harold;
Kumar, Harpal S.

Publication type:

Article

Casein kinase 2 associates with and phosphorylates Dishevelled.

Published in:

EMBO Journal, 1997, v. 16, n. 11, p. 3089, doi. 10.1093/emboj/16.11.3089

By:

Willert, Karl;
Brink, Marcel;
Wodarz, Andreas;
Varmus, Harold;
Nusse, Roel

Publication type:

Article

NIH funds support more than a researcher's own lab.

Published in:

2008

By:

Varmus, Harold

Publication type:

Letter

DOK2 Inhibits EGFR-Mutated Lung Adenocarcinoma.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079526

By:

Berger, Alice H.;
Chen, Ming;
Morotti, Alessandro;
Janas, Justyna A.;
Niki, Masaru;
Bronson, Roderick T.;
Taylor, Barry S.;
Ladanyi, Marc;
Van Aelst, Linda;
Politi, Katerina;
Varmus, Harold E.;
Pandolfi, Pier Paolo

Publication type:

Article

Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors.

Published in:

PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0006932

By:

Yi-Chieh Nancy Du;
Klimstra, David S.;
Varmus, Harold

Publication type:

Article

Nucleotide sequences at host-proviral junctions for mouse mammary tumour virus.

Published in:

Nature, 1981, v. 289, n. 5795, p. 253, doi. 10.1038/289253a0

By:

Majors, John E.;
Varmus, Harold E.

Publication type:

Article

Endogenous mammary tumour virus DNA varies among wild mice and segregates during inbreeding.

Published in:

Nature, 1979, v. 278, n. 5703, p. 418, doi. 10.1038/278418a0

By:

Cohen, J. Craig;
Varmus, Harold E.

Publication type:

Article

Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma.

Published in:

eLife, 2015, p. 1, doi. 10.7554/eLife.06907

By:

Unni, Arun M.;
Lockwood, William W.;
Zejnullahu, Kreshnik;
Shih-Queen Lee-Lin;
Varmus, Harold

Publication type:

Article

The Absence of p53 Promotes Metastasis in a Novel Somatic Mouse Model for Hepatocellular Carcinoma.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 4, p. 1228, doi. 10.1128/MCB.25.4.1228-1237.2005

By:

Lewis, Brian C.;
Klimstra, David S.;
Socci, Nicholas D.;
Xu, Su;
Koutcher, Jason A.;
Varmus, Harold E.

Publication type:

Article

Casein Kinase I∊ Modulates the Signaling Specificities of Dishevelled.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 5, p. 2000, doi. 10.1128/MCB.24.5.2000-2011.2004

By:

Cong, Feng;
Schweizer, Liang;
Varmus, Harold

Publication type:

Article

Requirement for a Nuclear Function of β-Catenin in Wnt Signaling.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 23, p. 8462, doi. 10.1128/MCB.23.23.8462-8470.2003

By:

Feng Cong, Carol W.;
Liang Schweizer;
Chamorro, Mario;
Varmus, Harold

Publication type:

Article

CLOSING THOUGHTS.

Published in:

Oncology (08909091), 2007, v. 21, n. 11, p. 1408

By:

Zerhouni, Elias A.;
Niederhuber, John E.;
Raghavan, Derek;
Ettinger, David S.;
Rosen, Steve;
Tempero, Margaret;
Varmus, Harold;
Davidson, Nancy;
Vogelstein, Bert

Publication type:

Article

Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting.

Published in:

Nature, 1989, v. 337, n. 6205, p. 364, doi. 10.1038/337364a0

By:

Chang, Lung-Ji;
Pryciak, Peter;
Ganem, Don;
Varmus, Harold E.

Publication type:

Article