Works matching DE "RAPAMYCIN"

Results: 5000

Transplacental sirolimus: a new treatment strategy for life-threatening fetal cardiac rhabdomyomas—a case report.

Published in:

2025

By:

Uno, Kaname;
Nomura, Yoji;
Kawaguchi, Masahiro;
Ebina, Anna;
Imanishi, Rina;
Kawai, Satoru;
Hayakawa, Hiromi

Publication type:

Letter

CRISPRi screening identifies PIKfyve as a co‐therapeutic target for obinutuzumab.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 5, p. 1, doi. 10.1002/ctm2.70333

By:

Kim, Yerim;
Oh, Jinkyung;
Kim, Jeong Ryeol;
Lee, Donghyuk;
Kim, Joo Young

Publication type:

Article

Verjüngen statt Ersetzen -- ein Paradigmenwechsel in der Ästhetischen Medizin.

Published in:

Kosmetische Medizin + Ästhetische Chirurgie, 2025, v. 46, n. 2, p. 92

By:

Wollina, Uwe

Publication type:

Article

Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in systemic lupus erythematosus Open Access.

Published in:

Rheumatology, 2025, v. 64, n. 6, p. 3964, doi. 10.1093/rheumatology/keae662

By:

Ai, Minji;
Zhou, Xian;
Carrer, Michele;
Jafar-nejad, Paymaan;
Li, Yanfeng;
Gades, Naomi;
Alexander, Mariam;
Bautista-Vargas, Mario;
Duarte-García, Alí;
Zeng, Hu

Publication type:

Article

Rare Case of Tacrolimus-Induced Acute Pancreatitis in a Liver Transplant Recipient.

Published in:

ACG Case Reports Journal, 2025, v. 12, n. 5, p. 1, doi. 10.14309/crj.0000000000001659

By:

Prado, Renan;
Chatterjee, Arjun;
Zaalishvili, Zurabi;
Kundu, Rupayan;
Junna, Shilpa;
Sengupta, Shreya;
Zein, Nizar;
Mohiuddin, Syed A.

Publication type:

Article

The Bi-steric Inhibitor RMC-5552 Reduces mTORC1 Signaling and Growth in Lymphangioleiomyomatosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 72, n. 6, p. 643, doi. 10.1165/rcmb.2024-0242OC

By:

Evans, Jilly F.;
Ledwell, Owen A.;
Tang, Yan;
Rue, Ryan;
Mukhitov, Alexander R.;
Diesler, Rémi;
Lin, Susan M.;
Vanka, Kanth Swaroop;
Basil, Maria C.;
Cantu, Edward;
Henske, Elizabeth P.;
Krymskaya, Vera P.

Publication type:

Article

Editorial: The role of inflammation and immune control in digestive disease and therapeutic approaches.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1621130

By:

Wang, Zhaoyang;
Wang, Shuai

Publication type:

Article

Safety and efficacy of sirolimus combined with cyclosporine in primary membranous nephropathy: a randomized controlled trial.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04173-0

By:

Wang, Fang;
Yang, Chao;
Shu, Yue;
Lin, Cai-xia;
Yao, Yao;
Li, Yue;
Zhang, Yi-miao;
Wang, Xin;
Meng, Li-qiang;
Cheng, Xu-yang;
Liu, Gang;
Zhao, Ming-hui;
Cui, Zhao

Publication type:

Article

Novel Approaches in the Age of Targeted Therapy.

Published in:

Oncology (08909091), 2008, v. 22, n. 14, p. 1617

By:

Yao, James C.

Publication type:

Article

Drug Essentials mTOR Inhibitors.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 43

By:

Wilkes, Gail M.

Publication type:

Article

Evolving Role of Novel Targeted Agents in Renal Cell Carcinoma.

Published in:

Oncology (08909091), 2007, v. 21, n. 10, p. 1175

By:

Hutson, Thomas E.;
Figlin, Robert A.

Publication type:

Article

mTOR: restricted access.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 656, doi. 10.1038/nsmb.2610

By:

Larochelle, Stéphane

Publication type:

Article

What reimbursement for coronary revascularization with drug-eluting stents?

Published in:

2004

By:

Tarricone, Rosanna;
Marchetti, Monia;
Lamotte, Mark;
Annemans, Lieven;
de Jong, Peter

Publication type:

journal article

Beyond The Glutamate N-methyl D-aspartate Receptor in Major Depressive Disorder: The mTOR Signaling Pathway.

Published in:: Klinik Psikofarmakoloji Bulteni, 2011, v. 21, n. 1, p. 1, doi. 10.5350/kpb-bcp201121101
Publication type:: Article

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 4, p. 266, doi. 10.1038/nrmicro1855

By:

Buchkovich, Nicholas J.;
Yu, Yongjun;
Zampieri, Carisa A.;
Alwine, James C.

Publication type:

Article

Expression Levels and Clinical Significance of WEE1 and mTOR in Triple-Negative Breast Cancer.

Published in:

Indian Journal of Surgery, 2025, v. 87, n. 1, p. 142, doi. 10.1007/s12262-024-04123-9

By:

Zu, Caixia;
Chang, Donghua;
Shu, Yile;
Wu, Leijuan;
Liu, Fei

Publication type:

Article

Deciphering the role of rapamycin in modulating decidual senescence: implications for decidual remodeling and implantation failure.

Published in:

Journal of Assisted Reproduction & Genetics, 2024, v. 41, n. 9, p. 2441, doi. 10.1007/s10815-024-03207-5

By:

Kendirci-Katirci, Remziye;
Sati, Leyla;
Celik-Ozenci, Ciler

Publication type:

Article

Altered expression of activator proteins that control follicle reserve after ovarian tissue cryopreservation/transplantation and primordial follicle loss prevention by rapamycin.

Published in:

Journal of Assisted Reproduction & Genetics, 2020, v. 37, n. 9, p. 2119, doi. 10.1007/s10815-020-01875-7

By:

Celik, Soner;
Ozkavukcu, Sinan;
Celik-Ozenci, Ciler

Publication type:

Article

mTOR inhibitor sirolimus negatively impacts in vitro fertilization outcomes.

Published in:

Journal of Assisted Reproduction & Genetics, 2019, v. 36, n. 5, p. 947, doi. 10.1007/s10815-019-01439-4

By:

Wald, Kaitlyn;
Cakmak, Hakan;
Noel, Martha

Publication type:

Article

Assessment of mTOR pathway molecules during implantation in rats.

Published in:

Biotechnic & Histochemistry, 2017, v. 92, n. 6, p. 450, doi. 10.1080/10520295.2017.1350749

By:

Ekizceli, G.;
Inan, S.;
Oktem, G.;
Onur, E.;
Ozbilgin, K.

Publication type:

Article

Dysregulated expression of the key effectors of the mammalian target of rapamycin signalling pathway in cutaneous papillomas of dogs.

Published in:

Veterinary & Comparative Oncology, 2019, v. 17, n. 4, p. 522, doi. 10.1111/vco.12516

By:

Sanz Ressel, Berenice L.;
Massone, Adriana R.;
Barbeito, Claudio G.

Publication type:

Article

Comparative analysis of MAPK and PI3K/AKT pathway activation and inhibition in human and canine melanoma.

Published in:

Veterinary & Comparative Oncology, 2015, v. 13, n. 3, p. 288, doi. 10.1111/vco.12044

By:

Fowles, J. S.;
Denton, C. L.;
Gustafson, D. L.

Publication type:

Article

High Incidence of Ovarian Cysts in Women Receiving mTOR Inhibitors After Renal Transplantation.

Published in:

Journal of Women's Health (15409996), 2018, v. 27, n. 3, p. 394, doi. 10.1089/jwh.2017.6451

By:

Bachmann, Friederike;
Glander, Petra;
Budde, Klemens;
Bachmann, Cornelia

Publication type:

Article

A Bioorthogonal Small-Molecule-Switch System for Controlling Protein Function in Live Cells.

Published in:

Angewandte Chemie, 2014, v. 126, n. 38, p. 10213, doi. 10.1002/ange.201403463

By:

Liu, Peng;
Calderon, Abram;
Konstantinidis, Georgios;
Hou, Jian;
Voss, Stephanie;
Chen, Xi;
Li, Fu;
Banerjee, Soumya;
Hoffmann, Jan-Erik;
Theiss, Christiane;
Dehmelt, Leif;
Wu, Yao-Wen

Publication type:

Article

Rapidly Reversible Manipulation of Molecular Activity with Dual Chemical Dimerizers.

Published in:

Angewandte Chemie, 2013, v. 125, n. 25, p. 6578, doi. 10.1002/ange.201301219

By:

Lin, Yu-Chun;
Nihongaki, Yuta;
Liu, Tzu-Yu;
Razavi, Shiva;
Sato, Moritoshi;
Inoue, Takanari

Publication type:

Article

Oligogalacturonides inhibit growth and induce changes in S6K phosphorylation in maize ( Zea mays L. var. Chalqueño).

Published in:

Plant Growth Regulation, 2012, v. 67, n. 2, p. 151, doi. 10.1007/s10725-012-9672-8

By:

Peña-Uribe, Cesar;
García-Pineda, Ernesto;
Beltrán-Peña, Elda;
Reyes de la Cruz, Homero

Publication type:

Article

A double inducible cell ablation system for eliminating senescent astrocytes via apoptosis.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09297-9

By:

Wang, Xiaoling;
Deng, Yuxin;
Xiao, Yan;
Wang, Fan;
Tang, Zhi;
Qi, Xiaolan

Publication type:

Article

Two mTOR inhibitors, rapamycin and Torin 1, differentially regulate iron-induced generation of mitochondrial ROS.

Published in:

BioMetals, 2017, v. 30, n. 6, p. 975, doi. 10.1007/s10534-017-0059-1

By:

Huang, Hui;
Chen, Jun;
Lu, Huiru;
Zhou, Mengxue;
Chai, Zhifang;
Hu, Yi

Publication type:

Article

Clinical trials and future potential of targeted therapy for ovarian cancer.

Published in:

International Journal of Clinical Oncology, 2012, v. 17, n. 5, p. 430, doi. 10.1007/s10147-012-0459-8

By:

Itamochi, Hiroaki;
Kigawa, Junzo

Publication type:

Article

Weekly administration of temsirolimus for heavily pretreated patients with clear cell carcinoma of the ovary: a report of six cases.

Published in:

International Journal of Clinical Oncology, 2011, v. 16, n. 5, p. 605, doi. 10.1007/s10147-010-0177-z

By:

Takano, Masashi;
Kikuchi, Yoshihiro;
Kudoh, Kazuya;
Goto, Tomoko;
Furuya, Kenichi;
Kikuchi, Ryoko;
Kita, Tsunekazu;
Fujiwara, Keiichi;
Shiozawa, Tanri;
Aoki, Daisuke

Publication type:

Article

Effects of the mTOR inhibitor sirolimus in patients with hepatocellular and cholangiocellular cancer.

Published in:

International Journal of Clinical Oncology, 2008, v. 13, n. 1, p. 66, doi. 10.1007/s10147-007-0733-3

By:

Rizell, Magnus;
Andersson, Mats;
Cahlin, Christian;
Hafström, Larsolof;
Olausson, Michael;
Lindnér, Per

Publication type:

Article

Antiaging effects of bioactive molecules isolated from plants and fungi.

Published in:

Medicinal Research Reviews, 2019, v. 39, n. 5, p. 1515, doi. 10.1002/med.21559

By:

Martel, Jan;
Ojcius, David M.;
Ko, Yun‐Fei;
Chang, Chih‐Jung;
Young, John D.

Publication type:

Article

Management of Complex Pulmonary Vein Stenosis at Altitude Combining Comprehensive Percutaneous Interventional Treatment with Sirolimus, Pulmonary Hypertension Medications and Intraluminal Imaging with Optical Coherence Tomography.

Published in:

Pediatric Cardiology, 2023, v. 44, n. 5, p. 1125, doi. 10.1007/s00246-023-03102-3

By:

Shorofsky, Michael J.;
Morgan, Gareth J.;
Mejia, Ernesto;
Rodriguez, Salvador A.;
Greene, Megan;
Sheaks, Paige;
Ivy, Dunbar;
Zablah, Jenny E.

Publication type:

Article

Serum Sirolimus Levels After Implantation of Third Generation Drug Eluting Cobalt Chromium Coronary Stent in Ductus Arteriosus in Neonates with Duct-Dependent Pulmonary Circulation.

Published in:

Pediatric Cardiology, 2020, v. 41, n. 7, p. 1354, doi. 10.1007/s00246-020-02381-4

By:

Sivakumar, Kothandam;
Pavithran, Sreeja;
Sonawane, Bhushan;
Rajendran, Monica;
Ramasamy, Rajeshkumar

Publication type:

Article

Is it necessary to investigate rapamycin-modulated autophagy during the development of experimental osteoporosis in female rat?

Published in:

2016

By:

Xu, M.-H.;
Li, X.;
Yuan, F.-L.

Publication type:

Letter

Rapamycin induces Smad activity in prostate cancer cell lines.

Published in:

Urological Research, 2003, v. 30, n. 6, p. 380, doi. 10.1007/s00240-002-0282-1

By:

van der Poel, H.G.;
Hanrahan, C.;
Zhong, H.;
Simons, J.W.

Publication type:

Article

m-TOR inhibitors and risk of Pneumocystis pneumonia after solid organ transplantation: a systematic review and meta-analysis.

Published in:

European Journal of Clinical Pharmacology, 2019, v. 75, n. 11, p. 1471, doi. 10.1007/s00228-019-02730-0

By:

Ghadimi, Maryam;
Mohammadpour, Zinat;
Dashti-Khavidaki, Simin;
Milajerdi, Alireza

Publication type:

Article

The evaluation of potential pharmacokinetic interaction between sirolimus and tacrolimus in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 4, p. 835, doi. 10.1007/s00228-012-1407-2

By:

Tortorici, Michael;
Parks, Virginia;
Matschke, Kyle;
Korth-Bradley, Joan;
Patat, Alain

Publication type:

Article

Repeat-dose sirolimus pharmacokinetics and pharmacodynamics in patients with hepatic allografts.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 5, p. 589, doi. 10.1007/s00228-011-1172-7

By:

Reichen, Jürg;
Stickel, Felix;
Bhattacharya, Indranil;
Matschke, Kyle;
Maller, Eric;
Korth-Bradley, Joan

Publication type:

Article

The pharmacokinetics of Biolimus A9 after elution from the BioMatrix II stent in patients with coronary artery disease: The Stealth PK Study.

Published in:

European Journal of Clinical Pharmacology, 2011, v. 67, n. 4, p. 389, doi. 10.1007/s00228-010-0895-1

By:

Ostojic, Miodrag;
Perisic, Zoran;
Sagic, Dragan;
Jung, Robert;
Zhang, Yan-Ling;
Bendrick-Peart, Jamie;
Betts, Ronald;
Christians, Uwe

Publication type:

Article

Differentiation of innovator versus generic cyclosporine via a drug interaction on sirolimus.

Published in:

European Journal of Clinical Pharmacology, 2006, v. 62, n. 5, p. 361, doi. 10.1007/s00228-006-0109-z

By:

Kovarik, John M.;
Noe, Adele;
Yibin Wang;
Mueller, Irene;
DeNucci, Gilberto;
Schmouder, Robert L.

Publication type:

Article

A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 91, n. 5, p. 1389, doi. 10.1007/s00253-011-3348-6

By:

Won Seok Jung;
Young Ji Yoo;
Je Won Park;
Sung Ryeol Park;
Ah Reum Han;
Yeon Hee Ban;
Eun Ji Kim;
Kim, Eunji;
Yeo Joon Yoon

Publication type:

Article

Methylglyoxal activates Gcn2 to phosphorylate eIF2α independently of the TOR pathway in Saccharomyces cerevisiae.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 86, n. 6, p. 1887, doi. 10.1007/s00253-009-2411-z

By:

Nomura, Wataru;
Maeta, Kazuhiro;
Kita, Keiko;
Izawa, Shingo;
Inoue, Yoshiharu

Publication type:

Article

Generation of high-yield rapamycin-producing strains through protoplasts-related techniques.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 83, n. 3, p. 507, doi. 10.1007/s00253-009-1918-7

By:

Chen, Xiyang;
Wei, Peilian;
Fan, Limei;
Yang, Dong;
Zhu, Xiangchen;
Shen, Wenhe;
Xu, Zhinan;
Cen, Peilin

Publication type:

Article

Growth of Streptomyces hygroscopicus in rotating-wall bioreactor under simulated microgravity inhibits rapamycin production.

Published in:

Applied Microbiology & Biotechnology, 2000, v. 54, n. 1, p. 33, doi. 10.1007/s002539900303

By:

Fang, A.;
Pierson, D. L.;
Mishra, S. K.;
Demain, A. L.

Publication type:

Article

Valine supplementation during late pregnancy in gilts increases colostral protein synthesis through stimulating mTOR signaling pathway in mammary cells.

Published in:

Amino Acids, 2019, v. 51, n. 10-12, p. 1547, doi. 10.1007/s00726-019-02790-7

By:

Che, Long;
Xu, Mengmeng;
Gao, Kaiguo;
Wang, Li;
Yang, Xuefen;
Wen, Xiaolu;
Xiao, Hao;
Jiang, Zongyong;
Wu, De

Publication type:

Article

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion.

Published in:

Amino Acids, 2018, v. 50, n. 10, p. 1377, doi. 10.1007/s00726-018-2613-8

By:

Huseinovic, Angelina;
Dekker, Stefan J.;
Boogaard, Bob;
Vermeulen, Nico. P. E.;
Kooter, Jan M.;
Vos, J. Chris

Publication type:

Article

N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways.

Published in:

Amino Acids, 2017, v. 49, n. 12, p. 1915, doi. 10.1007/s00726-017-2389-2

By:

Yi, Dan;
Hou, Yongqing;
Xiao, Hang;
Wang, Lei;
Zhang, Yue;
Chen, Hongbo;
Wu, Tao;
Ding, Binying;
Hu, Chien-An;
Wu, Guoyao

Publication type:

Article

Rag GTPase in amino acid signaling.

Published in:

Amino Acids, 2016, v. 48, n. 4, p. 915, doi. 10.1007/s00726-016-2171-x

By:

Kim, Joungmok;
Kim, Eunjung

Publication type:

Article

Chronic activation of mTOR complex 1 by branched chain amino acids and organ hypertrophy.

Published in:

Amino Acids, 2015, v. 47, n. 6, p. 1167, doi. 10.1007/s00726-015-1944-y

By:

Neishabouri, S.;
Hutson, S.;
Davoodi, J.

Publication type:

Article