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Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα.
- Published in:
- Nature Medicine, 2001, v. 7, n. 10, p. 1133, doi. 10.1038/nm1001-1133
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- Publication type:
- Article
Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling.
- Published in:
- 2011
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- Publication type:
- journal article
An energetic tale of AMPK-independent effects of metformin.
- Published in:
- 2010
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- Publication type:
- journal article
Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation.
- Published in:
- 2008
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- Publication type:
- journal article
Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.
- Published in:
- 2008
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- Publication type:
- journal article
Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis.
- Published in:
- 2005
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- Publication type:
- journal article
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury.
- Published in:
- Journal of Clinical Investigation, 2004, v. 114, n. 4, p. 495, doi. 10.1172/JCI200419297
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- Publication type:
- Article
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury.
- Published in:
- 2004
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- Publication type:
- journal article
Regulation of Gastric Acid Secretion by PKB/Akt2.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2010, v. 25, n. 6, p. 695, doi. 10.1159/000315089
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- Publication type:
- Article
Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.
- Published in:
- Science Signaling, 2015, v. 8, n. 376, p. 1, doi. 10.1126/scisignal.2005482
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- Publication type:
- Article
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration.
- Published in:
- Nature Medicine, 2012, v. 18, n. 6, p. 934, doi. 10.1038/nm.2744
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- Publication type:
- Article
Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
- Published in:
- Nature Medicine, 2012, v. 18, n. 3, p. 388, doi. 10.1038/nm.2686
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- Publication type:
- Article
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.
- Published in:
- Nature Medicine, 2011, v. 17, n. 1, p. 55, doi. 10.1038/nm.2277
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- Publication type:
- Article
Convergent evidence for impaired AKT1-GSK3ß signaling in schizophrenia.
- Published in:
- Nature Genetics, 2004, v. 36, n. 2, p. 131, doi. 10.1038/ng1296
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- Publication type:
- Article
Lipolysis: more than just a lipase.
- Published in:
- Journal of Cell Biology, 2003, v. 161, n. 6, p. 1011, doi. 10.1083/jcb.200306008
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- Publication type:
- Article
Tolerability, safety and pharmacodynamics of oral, small‐molecule glucagon‐like peptide‐1 receptor agonist danuglipron for type 2 diabetes: A 12‐week, randomized, placebo‐controlled, Phase 2 study comparing different dose‐escalation schemes
- Published in:
- Diabetes, Obesity & Metabolism, 2023, v. 25, n. 10, p. 2805, doi. 10.1111/dom.15168
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- Publication type:
- Article
mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0126240
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- Publication type:
- Article
Akt Deficiency Attenuates Muscle Size and Function but Not the Response to ActRIIB Inhibition.
- Published in:
- PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012707
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- Publication type:
- Article
Signaling Pathways Mediating Insulin-Stimulated Glucose Transport.
- Published in:
- Annals of the New York Academy of Sciences, 1999, v. 892, n. 1, p. 169, doi. 10.1111/j.1749-6632.1999.tb07795.x
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- Publication type:
- Article
Genomics: Drugs, diabetes and cancer.
- Published in:
- 2011
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- Publication type:
- Opinion
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1α transcription coactivator.
- Published in:
- 2007
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- Publication type:
- Letter
Efficacy and Safety of Oral Small Molecule Glucagon-Like Peptide 1 Receptor Agonist Danuglipron for Glycemic Control Among Patients With Type 2 Diabetes: A Randomized Clinical Trial.
- Published in:
- JAMA Network Open, 2023, v. 6, n. 5, p. e2314493, doi. 10.1001/jamanetworkopen.2023.14493
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- Publication type:
- Article
SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.91114
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- Publication type:
- Article
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila.
- Published in:
- Nature Cell Biology, 2001, v. 3, n. 6, p. 596, doi. 10.1038/35078571
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- Publication type:
- Article
Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.
- Published in:
- Nature Cell Biology, 1999, v. 1, n. 8, p. 500, doi. 10.1038/70293
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- Publication type:
- Article
Akt2 and SGK3 are both determinants of postnatal hair follicle development.
- Published in:
- FASEB Journal, 2009, v. 23, n. 9, p. 3193, doi. 10.1096/fj.08-123729
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- Publication type:
- Article
Hepatic Gi signaling regulates whole-body glucose homeostasis.
- Published in:
- 2018
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- Publication type:
- journal article
mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion.
- Published in:
- 2017
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- Publication type:
- journal article
Retraction: Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.
- Published in:
- Nature Immunology, 2014, v. 15, n. 10, p. 996, doi. 10.1038/ni0910-996
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- Publication type:
- Article
Natural and inducible T<sub>H</sub>17 cells are regulated differently by Akt and mTOR pathways.
- Published in:
- Nature Immunology, 2013, v. 14, n. 6, p. 611, doi. 10.1038/ni.2607
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- Publication type:
- Article
SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding.
- Published in:
- Nature Communications, 2016, v. 7, n. 7, p. 12180, doi. 10.1038/ncomms12180
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- Publication type:
- Article
Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo.
- Published in:
- Nature Communications, 2015, v. 6, n. 5, p. 7078, doi. 10.1038/ncomms8078
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- Publication type:
- Article
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.
- Published in:
- Nature Communications, 2014, v. 5, n. 8, p. 4535, doi. 10.1038/ncomms5535
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- Publication type:
- Article
Regulation of Glucose and Lipid Metabolism by Akt/PKB.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A44, doi. 10.1096/fasebj.21.5.a44-e
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- Publication type:
- Article
PGC-1α gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle.
- Published in:
- FASEB Journal, 2005, v. 19, n. 14, p. 2072, doi. 10.1096/fj.05-3993fje
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- Publication type:
- Article
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
- Published in:
- Nature, 2004, v. 428, n. 6982, p. 569, doi. 10.1038/nature02440
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- Publication type:
- Article
Dialogue between muscle and fat.
- Published in:
- Nature, 2001, v. 409, n. 6821, p. 672, doi. 10.1038/35055643
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- Publication type:
- Article
A Role for Akt2 in Cardiac Morphology but not Non-Insulin Stimulated Glucose Transport in Glut4 Knockout Mice.
- Published in:
- Diabetes, 2007, v. 56, p. A328
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- Publication type:
- Article
Coupling of Oxidative Metabolism to Muscular Work in Healthy and Insulin Resistant Conscious Mice: Role of AMPK Signaling.
- Published in:
- Diabetes, 2007, v. 56, p. A63
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- Publication type:
- Article
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
- Published in:
- Nature, 2013, v. 494, n. 7436, p. 256, doi. 10.1038/nature11808
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- Publication type:
- Article
Differential regulation of Akt/protein kinase B isoforms during cell cycle progression
- Published in:
- FEBS Letters, 2009, v. 583, n. 4, p. 685, doi. 10.1016/j.febslet.2009.01.005
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- Publication type:
- Article
Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function.
- Published in:
- Hippocampus, 2012, v. 22, n. 2, p. 230, doi. 10.1002/hipo.20887
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- Publication type:
- Article
Addressing unmet needs for people with cancer cachexia: recommendations from a multistakeholder workshop.
- Published in:
- Journal of Cachexia, Sarcopenia & Muscle, 2022, v. 13, n. 2, p. 1418, doi. 10.1002/jcsm.12910
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- Publication type:
- Article
A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice.
- Published in:
- Human Molecular Genetics, 2011, v. 20, n. 5, p. 988, doi. 10.1093/hmg/ddq544
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- Publication type:
- Article
Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase-Dependent Pathway That Is Impaired With Obesity.
- Published in:
- Diabetes, 2009, v. 58, n. 4, p. 829, doi. 10.2337/db08-0659
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- Publication type:
- Article