Works matching DE "SIGMA-1 receptor"
Results: 105
Disruptions in serotonin- and kynurenine pathway metabolism in post-COVID: biomarkers and treatment.
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- Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1532383
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- Article
SA4503 Mitigates Adriamycin-Induced Nephropathy via Sigma-1 Receptor in Animal and Cell-Based Models.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 172, doi. 10.3390/ph18020172
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- Article
Sigma-1 receptor activation attenuates DOX-induced cardiotoxicity by alleviating endoplasmic reticulum stress and mitochondrial calcium overload via PERK and IP3R-VDAC1-MCU signaling pathways.
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- Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00617-y
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- Article
Dextromethorphan/bupropion in major depressive disorder: a profile of its use.
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- Drugs & Therapy Perspectives, 2023, v. 39, n. 8, p. 270, doi. 10.1007/s40267-023-01009-w
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- Article
Interaction of Afobazole with Sigma-1 Receptors in the Mouse Brain.
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- Pharmaceutical Chemistry Journal, 2015, v. 49, n. 1, p. 7, doi. 10.1007/s11094-015-1212-1
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- Article
Interaction of 2-mercaptobenzimidazole derivatives with sigma-1 receptors.
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- Pharmaceutical Chemistry Journal, 2012, v. 46, n. 6, p. 334, doi. 10.1007/s11094-012-0793-1
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- Article
Sigma receptor type 1 gene variation in a group of Polish patients with Alzheimer's disease and mild cognitive impairment.
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- 2007
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- Publication type:
- Journal Article
A systematic review and meta-analysis, investigating dose and time of fluvoxamine treatment efficacy for COVID-19 clinical deterioration, death, and Long-COVID complications.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-64260-9
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- Article
Sigma-1 Receptor Modulates CFA-Induced Inflammatory Pain via Sodium Channels in Small DRG Neurons.
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- Biomolecules (2218-273X), 2025, v. 15, n. 1, p. 73, doi. 10.3390/biom15010073
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- Article
Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain.
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- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00678
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- Article
Ligands Exert Biased Activity to Regulate Sigma 1 Receptor Interactions With Cationic TRPA1, TRPV1, and TRPM8 Channels.
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- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00634
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- Publication type:
- Article
Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression.
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- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00017
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- Article
The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells.
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- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00423
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- Publication type:
- Article
NMDA Receptors Are Upregulated and Trafficked to the Plasma Membrane after Sigma-1 Receptor Activation in the Rat Hippocampus.
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- Journal of Neuroscience, 2014, v. 34, n. 34, p. 11325, doi. 10.1523/JNEUROSCI.0458-14.2014
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- Article
Point Mutation in Sigma-1 Receptor Inhibits Neuronal Cell Differentiation.
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- FASEB Journal, 2007, v. 21, n. 6, p. A992
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- Article
Ayahuasca and its interaction with the sigma-1 receptor: a potential treatment for COVID-19.
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- Brazilian Journal of Psychiatry / Revista Brasileira de Psiquiatria, 2022, v. 44, n. 4, p. 465, doi. 10.47626/1516-4446-2022-2541
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- Article
Stalking in clinical psychiatry: when the doctor becomes the victim.
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- Brazilian Journal of Psychiatry / Revista Brasileira de Psiquiatria, 2022, v. 44, n. 4, p. 464, doi. 10.47626/1516-4446-2022-2464
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- Publication type:
- Article
Sigma-1 receptor antagonist haloperidol attenuates Ca responses induced by glutoxim and molixan in macrophages.
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- Doklady Biochemistry & Biophysics, 2017, v. 472, n. 1, p. 74, doi. 10.1134/S1607672917010227
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- Publication type:
- Article
Induction of Hypothermic Conditions Associated with Increased Micronuclei Formation in Sigma-1 Receptor Knockout Mice after Administration of the Antipsychotic Compound E-5842.
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- Environmental & Molecular Mutagenesis, 2008, v. 49, n. 9, p. 727, doi. 10.1002/em.20428
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- Publication type:
- Article
New Long-Term Data Suggest Continued Blarcamesine Efficacy in Alzheimer Disease Up to 4 Years.
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- Patient Care (Online), 2025, p. 1
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- Publication type:
- Article
Normalization of Calcium Balance in Striatal Neurons in Huntington's Disease: Sigma 1 Receptor as a Potential Target for Therapy.
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- Biochemistry (00062979), 2021, v. 86, n. 4, p. 471, doi. 10.1134/S0006297921040076
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- Article
Sigma 1 receptor modulators as a new weapon against multiple sclerosis.
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- BioDiscovery, 2017, p. 1, doi. 10.3897/biodiscovery.20.e14565
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- Publication type:
- Article
Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([<sup>124</sup>I]IPAG).
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- 2020
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- Publication type:
- journal article
Cutamesine Overcomes REM Sleep Deprivation-Induced Memory Loss: Relationship to Sigma-1 Receptor Occupancy.
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- Molecular Imaging & Biology, 2015, v. 17, n. 3, p. 364, doi. 10.1007/s11307-014-0808-2
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- Publication type:
- Article
Altered Sigma-1 Receptor Expression in Two Animal Models of Cognitive Impairment.
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- Molecular Imaging & Biology, 2015, v. 17, n. 2, p. 231, doi. 10.1007/s11307-014-0780-x
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- Publication type:
- Article
Analysis of Sigma-1 Receptor Antagonist BD1047 Effect on Upregulating Proteins in HIV-1-Infected Macrophages Exposed to Cocaine Using Quantitative Proteomics.
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- Biomedicines, 2024, v. 12, n. 9, p. 1934, doi. 10.3390/biomedicines12091934
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- Publication type:
- Article
The Sigma-1 Receptor Exacerbates Cardiac Dysfunction Induced by Obstructive Nephropathy: A Role for Sexual Dimorphism.
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- Biomedicines, 2024, v. 12, n. 8, p. 1908, doi. 10.3390/biomedicines12081908
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- Publication type:
- Article
The role of 5-HTergic neuron activation in the rapid antidepressant-like effects of hypidone hydrochloride (YL-0919) in mice.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1428485
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- Publication type:
- Article
Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist.
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- Psychopharmacology, 2009, v. 205, n. 2, p. 327, doi. 10.1007/s00213-009-1548-x
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- Publication type:
- Article
N, N-Dimethyltryptamine, a natural hallucinogen, ameliorates Alzheimer's disease by restoring neuronal Sigma-1 receptor-mediated endoplasmic reticulum-mitochondria crosstalk.
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- Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01462-3
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- Publication type:
- Article
4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies.
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- Chemistry Central Journal, 2016, v. 10, p. 1, doi. 10.1186/s13065-016-0200-1
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- Publication type:
- Article
Chaperones vs. oxidative stress in the pathobiology of ischemic stroke.
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- Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1513084
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- Publication type:
- Article
The Effects of Terminal Tagging on Homomeric Interactions of the Sigma 1 Receptor.
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- Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01356
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- Publication type:
- Article
Long-Term Haloperidol Treatment Prolongs QT Interval and Increases Expression of Sigma 1 and IP<sub>3</sub> Receptors in Guinea Pig Hearts.
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- Tohoku Journal of Experimental Medicine, 2015, v. 236, n. 3, p. 199, doi. 10.1620/tjem.236.199
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- Article
High specific activity tritium labelling of some sigma-1 receptor agonists.
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- Journal of Radioanalytical & Nuclear Chemistry, 2012, v. 292, n. 1, p. 19, doi. 10.1007/s10967-011-1369-3
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- Publication type:
- Article
The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation.
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- Inflammation Research, 2014, v. 63, n. 3, p. 231, doi. 10.1007/s00011-013-0692-2
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- Publication type:
- Article
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
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- Archives of Toxicology, 2024, v. 98, n. 10, p. 3323, doi. 10.1007/s00204-024-03805-3
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- Publication type:
- Article
Cocaine inhibits store-operated Ca<sup>2+</sup> entry in brain microvascular endothelial cells: critical role for sigma-1 receptors.
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- Biochemical Journal, 2016, v. 473, n. 1, p. 1, doi. 10.1042/BJ20150934
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- Publication type:
- Article
The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands.
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- Biochemical Journal, 2015, v. 466, n. 2, p. 263, doi. 10.1042/BJ20141321
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- Publication type:
- Article
Mechanisms and treatments of methamphetamine and HIV-1 co-induced neurotoxicity: a systematic review.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1423263
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- Publication type:
- Article
Sigma receptor type 1 knockout mice show a mild deficit in plasticity but no significant change in synaptic transmission in the CA1 region of the hippocampus.
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- Journal of Neurochemistry, 2016, v. 138, n. 5, p. 700, doi. 10.1111/jnc.13695
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- Publication type:
- Article
Effects of the selective sigma-1 receptor antagonist S1 RA on formalin-induced pain behavior and neurotransmitter release in the spinal cord in rats.
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- Journal of Neurochemistry, 2014, v. 129, n. 3, p. 484, doi. 10.1111/jnc.12648
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- Publication type:
- Article
Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells.
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- Journal of Neurochemistry, 2007, v. 102, n. 3, p. 812, doi. 10.1111/j.1471-4159.2007.04533.x
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- Publication type:
- Article
Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone.
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- Molecular Pain, 2022, p. 1, doi. 10.1177/17448069211069255
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- Publication type:
- Article
ALSUntangled #71: Nuedexta.
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- Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024, v. 25, n. 1/2, p. 218, doi. 10.1080/21678421.2023.2239292
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- Publication type:
- Article
Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-94079-7
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- Publication type:
- Article
Sigma-1 receptor ligand PD144418 and sigma-2 receptor ligand YUN-252 attenuate the stimulant effects of methamphetamine in mice.
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- Psychopharmacology, 2019, v. 236, n. 11, p. 3147, doi. 10.1007/s00213-019-05268-2
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- Publication type:
- Article
The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats.
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- Psychopharmacology, 2016, v. 233, n. 7, p. 1269, doi. 10.1007/s00213-016-4209-x
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- Publication type:
- Article
Sigma 1 receptor activation regulates brain-derived neurotrophic factor through NR2A-CaMKIV-TORC1 pathway to rescue the impairment of learning and memory induced by brain ischaemia/reperfusion.
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- Psychopharmacology, 2015, v. 232, n. 10, p. 1779, doi. 10.1007/s00213-014-3809-6
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- Publication type:
- Article
Dose-dependent sigma-1 receptor occupancy by donepezil in rat brain can be assessed with C-SA4503 and microPET.
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- Psychopharmacology, 2014, v. 231, n. 20, p. 3997, doi. 10.1007/s00213-014-3533-2
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- Publication type:
- Article