Works matching DE "DRUG lipophilicity"
Results: 681
Antioxidative Properties of Vanillic Acid Esters in Multiple Antioxidant Assays.
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- Bioscience, Biotechnology & Biochemistry, 2012, v. 76, n. 2, p. 314, doi. 10.1271/bbb.110700
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Structure-Activity Relationship of Anthelmintic Cyclooctadepsipeptides.
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- Bioscience, Biotechnology & Biochemistry, 2011, v. 75, n. 7, p. 1354, doi. 10.1271/bbb.110129
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Relating Conformational Equilibria to Conformer‐Specific Lipophilicities: New Opportunities in Drug Discovery.
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- Angewandte Chemie, 2022, v. 134, n. 7, p. 1, doi. 10.1002/ange.202114862
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Comparative pharmacokinetics and pharmacodynamics of propranolol and atenolol in normolipaemic and hyperlipidaemic obese subjects.
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- Biopharmaceutics & Drug Disposition, 2003, v. 24, n. 5, p. 211
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Synthesis, Kinetics and Pharmacological Comparison of a Mutual Prodrug of Mefenamic Acid to Related Physical Mixture.
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- Pharmaceutical Chemistry Journal, 2014, v. 48, n. 4, p. 253, doi. 10.1007/s11094-014-1089-4
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Studies of the Lipophilic Components of a Dense Extract of the Herb Alfredia Cernua and its Nootropic Properties.
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- Pharmaceutical Chemistry Journal, 2014, v. 48, n. 3, p. 181, doi. 10.1007/s11094-014-1074-y
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Prediction of the Octanol-Water Partition Coefficients of N-Aryl-Substituted Anthranilic Acid Derivatives.
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- Pharmaceutical Chemistry Journal, 2014, v. 47, n. 12, p. 660, doi. 10.1007/s11094-014-1027-5
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Acute toxicity evaluation upon intravenous injection into mice: interspecies correlations, lipophilicity parameters, and physicochemical descriptors.
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- Pharmaceutical Chemistry Journal, 2012, v. 46, n. 2, p. 69, doi. 10.1007/s11094-012-0736-x
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Synthesis and antimicrobial activity of pyrimidinophanes with two uracil units and bridging nitrogen atoms.
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- Pharmaceutical Chemistry Journal, 2009, v. 43, n. 8, p. 448, doi. 10.1007/s11094-009-0331-y
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Bioavailability of coenzyme Q<sub>10</sub> in various pharmaceutical formulations.
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- Pharmaceutical Chemistry Journal, 2009, v. 43, n. 8, p. 468, doi. 10.1007/s11094-009-0330-z
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Lipophilicity of organic compounds calculated using structural similarity and molecular physicochemical descriptors.
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- Pharmaceutical Chemistry Journal, 2009, v. 43, n. 5, p. 258, doi. 10.1007/s11094-009-0280-5
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Composition of the lipophilic fraction of stinging nettle ( Urtica dioica L. and U. urens L.) homeopathic matrix tinctures.
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- Pharmaceutical Chemistry Journal, 2008, v. 42, n. 12, p. 699, doi. 10.1007/s11094-009-0204-4
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Experimental Adaptation of Staphylococcus Aureus to Sulfuryl Derivatives of Benzazolides.
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- Pharmaceutical Chemistry Journal, 2008, v. 42, n. 7, p. 377, doi. 10.1007/s11094-008-0136-4
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New approach to studying liposomes: Staining for visualization and determination of trapping efficiency by spectrophotometry using neutral red.
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- Pharmaceutical Chemistry Journal, 2007, v. 41, n. 5, p. 285, doi. 10.1007/s11094-007-0064-8
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Synthesis of anti-HIV nucleoside conjugates with lipophilic diol compounds.
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- Pharmaceutical Chemistry Journal, 2006, v. 40, n. 5, p. 276, doi. 10.1007/s11094-006-0108-5
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Isolation of saponins from table beetroot and primary evaluation of their pharmacological activity.
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- Pharmaceutical Chemistry Journal, 2005, v. 39, n. 12, p. 650, doi. 10.1007/s11094-006-0038-2
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Optimization of the Composition and Technology of Diazoline Tablets.
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- Pharmaceutical Chemistry Journal, 2005, v. 39, n. 8, p. 437, doi. 10.1007/s11094-005-0176-y
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Peculiarities in the Mass Transfer of Lipophilic Biologically Active Substances Isolated from Raw Plant Materials with a Two-Phase Extractant System.
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- Pharmaceutical Chemistry Journal, 2003, v. 37, n. 8, p. 425, doi. 10.1023/A:1027360014257
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Recent Advances in Improving the Bioavailability of Hydrophobic/Lipophilic Drugs and Their Delivery via Self-Emulsifying Formulations.
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- Colloids & Interfaces, 2023, v. 7, n. 1, p. 16, doi. 10.3390/colloids7010016
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Assessment of the matrix effect in quantifying lipophilic toxins in seafood.
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- Veterinarska Stanica, 2024, v. 55, n. 6, p. 611, doi. 10.46419/vs.55.6.5
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Baseline Lipophilicity Relationships in Human Cytochromes P450 Associated with Drug Metabolism.
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- Drug Metabolism Reviews, 2003, v. 35, n. 1, p. 1, doi. 10.1081/DMR-120018245
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220. ATYPICAL ENZYME KINETICS OBSERVED WITH CYTOCHROME P450 2C9.
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- 2002
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- Abstract
Leadlikeness and structural diversity of synthetic screening libraries.
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- Plant Foods for Human Nutrition, 2006, v. 61, n. 3, p. 377, doi. 10.1007/s11030-006-9040-6
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SVM approach for predicting LogP.
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- Plant Foods for Human Nutrition, 2006, v. 61, n. 3, p. 301, doi. 10.1007/s11030-006-9036-2
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Review of advances in the thin layer chromatography of pesticides: 2004-2006.
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- Journal of Environmental Science & Health. Part B. Pesticides, Food Contaminants & Agricultural Wastes, 2007, v. 42, n. 4, p. 429, doi. 10.1080/03601230701316440
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- Article
Synthesis and anticancer and lipophilic properties of 10-dialkylaminobutynyl derivatives of 1,8- and 2,7-diazaphenothiazines.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1132, doi. 10.3109/14756366.2015.1101092
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Synthesis, antiviral activity and structure–activity relationship of 1-(1-aryl-4,5-dihydro-1 H -imidazoline)-3-chlorosulfonylureas and products of their cyclization.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 5, p. 787, doi. 10.3109/14756366.2015.1069287
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The synthesis and biological activity of lipophilic derivatives of bicine conjugated with N<sup>3</sup>-(4-methoxyfumaroyl)- L-2,3-diaminopropanoic acid (FMDP)-an inhibitor of glucosamine-6-phosphate synthase.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2012, v. 27, n. 2, p. 167, doi. 10.3109/14756366.2011.582039
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Synthesis of new 8( S)-HETE analogs and their biological evaluation as activators of the PPAR nuclear receptors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 5, p. 653, doi. 10.3109/14756360903468171
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Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 5, p. 679, doi. 10.3109/14756360903514149
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Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2008, v. 23, n. 2, p. 213, doi. 10.1080/14756360701504826
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Anti-inflammatory and antioxidant activity of coumarins designed as potential fluorescent zinc sensors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 3, p. 287, doi. 10.1080/14756360601073914
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Quantitative structure-activity relationships (QSARs) in inhibitors of various cytochromes P450: The importance of compound lipophilicity.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 1, p. 1, doi. 10.1080/14756360600952183
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Lipophilicity Relationships in Inhibitors of CYP2C9 and CYP2C19 Enzymes.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2006, v. 21, n. 4, p. 385, doi. 10.1080/14756360600703313
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- Article
Inhibition of Butyrylcholinesterase by Phenothiazine Derivatives.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2002, v. 17, n. 3, p. 197, doi. 10.1080/1475636021000003165
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Prescription of lipophilic statins to Alzheimer's disease patients: some controversies to consider.
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- Neurological Sciences, 2011, v. 32, n. 2, p. 195, doi. 10.1007/s10072-010-0440-0
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- Article
氮酮对不同亲脂性中药有效成分的经皮促透作用研究.
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- Journal of Beijing University of Traditional Chinese Medicine, 2016, v. 39, n. 2, p. 155, doi. 10.3969/j.issn.1006-2157.2016.02.014
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Influence of the application area on finite dose permeation in relation to drug type applied.
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- Experimental Dermatology, 2012, v. 21, n. 3, p. 233, doi. 10.1111/j.1600-0625.2011.01424.x
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Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage.
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- Experimental Dermatology, 2007, v. 16, n. 11, p. 927, doi. 10.1111/j.1600-0625.2007.00616.x
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A novel lipophilic amiloride derivative efficiently kills chemoresistant breast cancer cells.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-71181-0
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- Article
Pharmacokinetics of anti-Mycobacterium avium-intracellulare disease drugs in silkworms.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-68248-3
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Current and Future Nano-Carrier-Based Approaches in the Treatment of Alzheimer's Disease.
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- Brain Sciences (2076-3425), 2023, v. 13, n. 2, p. 213, doi. 10.3390/brainsci13020213
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FC-57 Interspecies differences in the percutaneous permeation of substances with various lipophilicities.
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- 2004
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- Abstract
Pharmacokinetic/Pharmacodynamic Profile of Posaconazole.
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- Clinical Pharmacokinetics, 2010, v. 49, n. 6, p. 379
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- Article
Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic drugs.
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- International Journal of Pharmaceutical Investigation, 2015, v. 5, n. 4, p. 182, doi. 10.4103/2230-973X.167661
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A perspective overview on lipospheres as lipid carrier systems.
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- International Journal of Pharmaceutical Investigation, 2014, v. 4, n. 4, p. 149, doi. 10.4103/2230-973X.143112
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- Article
3D-QSAR COMFA, COMSIA STUDIES ON PYRAZOLO-FUSED AZADECALINS DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR ANTAGONISTS.
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- Pharma Science Monitor, 2012, v. 3, n. 4, p. 2027
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- Article
BIOLOGICAL ACTIVITIES OF FEW NITROGEN HETEROCYLES USING PASS AND LIPOPHILICITY USING ADME BOXES.
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- Pharma Science Monitor, 2012, v. 3, n. 4, p. 1994
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Augmented reduction of islet β-cell mass in Goto-Kakizaki rats fed high-fat diet and its suppression by pitavastatin treatment.
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- Journal of Diabetes Investigation, 2012, v. 3, n. 3, p. 235, doi. 10.1111/j.2040-1124.2011.00173.x
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- Article
Lipofi lik Ajan Toksisitesinde Yeni Ufuklar.
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- Journal of Academic Emergency Medicine / Akademik Acil Tip Olgu Sunumlari Dergisi, 2011, v. 10, n. 2, p. 80, doi. 10.5152/jaem.2011.019
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- Article