Works matching DE "ALLOSTERIC regulation"
Results: 1511
Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 1, p. 37, doi. 10.1038/nsmb.2924
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- Publication type:
- Article
Mechanism of allosteric activation of SAMHD1 by dGTP.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 11, p. 1304, doi. 10.1038/nsmb.2692
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- Publication type:
- Article
Defining the structural relationship between kainate-receptor deactivation and desensitization.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1054, doi. 10.1038/nsmb.2654
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- Publication type:
- Article
Allosteric mechanism of water-channel gating by Ca<sup>2+</sup>-calmodulin.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1085, doi. 10.1038/nsmb.2630
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- Publication type:
- Article
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 876, doi. 10.1038/nsmb.2595
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- Publication type:
- Article
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 900, doi. 10.1038/nsmb.2583
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- Publication type:
- Article
Allostery through DNA.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 410, doi. 10.1038/nsmb0413-410
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- Publication type:
- Article
Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 477, doi. 10.1038/nsmb.2522
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- Article
Structure and function of long noncoding RNAs in epigenetic regulation.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 3, p. 300, doi. 10.1038/nsmb.2480
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- Article
Protective degradation.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 13, doi. 10.1038/nsmb.2493
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- Publication type:
- Article
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 938, doi. 10.1038/nsmb.2367
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- Publication type:
- Article
AMP-activated protein kinase undergoes nucleotide-dependent conformational changes.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 716, doi. 10.1038/nsmb.2319
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- Publication type:
- Article
Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 437, doi. 10.1038/nsmb.2002
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- Publication type:
- Article
Mechanics of Hsp70 chaperones enables differential interaction with client proteins.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 345, doi. 10.1038/nsmb.2006
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- Publication type:
- Article
Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 316, doi. 10.1038/nsmb.2007
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- Publication type:
- Article
Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 288, doi. 10.1038/nsmb.1978
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- Publication type:
- Article
Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins.
- Published in:
- Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 364, doi. 10.1038/nsmb.1990
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- Publication type:
- Article
Enhanced interrogation: emerging strategies for cell signaling inhibition.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 646, doi. 10.1038/nsmb0610-646
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- Publication type:
- Article
Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome.
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- Nature Structural & Molecular Biology, 2009, v. 16, n. 2, p. 219, doi. 10.1038/nsmb.1547
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- Publication type:
- Article
Mapping a molecular link between allosteric inhibition and activation of the glycine receptor.
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- Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1084, doi. 10.1038/nsmb.1492
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- Publication type:
- Article
Factor B structure provides insights into activation of the central protease of the complement system.
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- Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 224, doi. 10.1038/nsmb1210
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- Publication type:
- Article
Dynamically driven protein allostery.
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- Nature Structural & Molecular Biology, 2006, v. 13, n. 9, p. 831, doi. 10.1038/nsmb1132
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- Publication type:
- Article
Disorder-order folding transitions underlie catalysis in the helicase motor of SecA.
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- Nature Structural & Molecular Biology, 2006, v. 13, n. 7, p. 594, doi. 10.1038/nsmb1108
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- Publication type:
- Article
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
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- Nature Structural & Molecular Biology, 2004, v. 11, n. 8, p. 747, doi. 10.1038/nsmb796
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- Publication type:
- Article
Allosteric inhibition of protein tyrosine phosphatase 1B.
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- Nature Structural & Molecular Biology, 2004, v. 11, n. 8, p. 730, doi. 10.1038/nsmb803
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- Publication type:
- Article
Correction: LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains.
- Published in:
- 2025
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- Publication type:
- Correction Notice
Integrated data-driven and experimental approaches to accelerate lead optimization targeting SARS-CoV-2 main protease.
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- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 8, p. 339, doi. 10.1007/s10822-023-00509-1
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- Publication type:
- Article
Computational insights into the molecular mechanisms of differentiated allosteric modulation at the mu opioid receptor by structurally similar bitopic modulators.
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- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 8, p. 879, doi. 10.1007/s10822-020-00309-x
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- Publication type:
- Article
Druggable exosites of the human kino-pocketome.
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- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 3, p. 219, doi. 10.1007/s10822-019-00276-y
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- Publication type:
- Article
Two-track virtual screening approach to identify both competitive and allosteric inhibitors of human small C-terminal domain phosphatase 1.
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- Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 8, p. 743, doi. 10.1007/s10822-017-0037-2
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- Publication type:
- Article
Allosteric modulation model of the mu opioid receptor by herkinorin, a potent not alkaloidal agonist.
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- Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 5, p. 467, doi. 10.1007/s10822-017-0016-7
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- Publication type:
- Article
Structural dynamics of native and V260E mutant C-terminal domain of HIV-1 integrase.
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- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 4, p. 371, doi. 10.1007/s10822-015-9830-y
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- Publication type:
- Article
Design of a colicin E7 based chimeric zinc-finger nuclease.
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- Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 8, p. 841, doi. 10.1007/s10822-014-9765-8
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- Publication type:
- Article
SAMPL4 & DOCK3.7: lessons for automated docking procedures.
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- Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 3, p. 201, doi. 10.1007/s10822-014-9722-6
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- Publication type:
- Article
Modeling activated states of GPCRs: the rhodopsin template.
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- Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 437, doi. 10.1007/s10822-006-9061-3
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- Publication type:
- Article
Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.
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- Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 405, doi. 10.1007/s10822-006-9053-3
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- Publication type:
- Article
Modeling activated states of GPCRs: the rhodopsin template.
- Published in:
- Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 437, doi. 10.1007/s10822-006-9061-3
- By:
- Publication type:
- Article
Identification of the Same Na-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions.
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- Journal of Molecular Evolution, 2015, v. 81, n. 5/6, p. 225, doi. 10.1007/s00239-015-9715-7
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- Publication type:
- Article
Calcimimetic and Calcilytic Drugs: Feats, Flops, and Futures.
- Published in:
- 2016
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- Publication type:
- journal article
Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift.
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- Pflügers Archiv: European Journal of Physiology, 2009, v. 458, n. 5, p. 877, doi. 10.1007/s00424-009-0687-6
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- Publication type:
- Article
In vivo investigations on the cholinesterase-inhibiting effects of tricyclic quinazolinimines: Scopolamine-induced cognitive impairments in rats are attenuated at low dosage and reinforced at higher dosage.
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- Pflügers Archiv: European Journal of Physiology, 2008, v. 455, n. 5, p. 895, doi. 10.1007/s00424-007-0325-0
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- Publication type:
- Article
Allosteric effects of external K<sup>+</sup> ions mediated by the aspartate of the GYGD signature sequence in the Kv2.1 K<sup>+</sup> channel.
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- Pflügers Archiv: European Journal of Physiology, 2006, v. 451, n. 6, p. 776, doi. 10.1007/s00424-005-1515-2
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- Publication type:
- Article
Allosteric receptor activation by the plant peptide hormone phytosulfokine.
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- Nature, 2015, v. 525, n. 7568, p. 265, doi. 10.1038/nature14858
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- Publication type:
- Article
Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.
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- Nature, 2015, v. 523, n. 7558, p. 111, doi. 10.1038/nature14405
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- Publication type:
- Article
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
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- Nature, 2015, v. 520, n. 7548, p. 511, doi. 10.1038/nature14367
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- Publication type:
- Article
Programmable RNA recognition and cleavage by CRISPR/Cas9.
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- Nature, 2014, v. 516, n. 7530, p. 263, doi. 10.1038/nature13769
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- Publication type:
- Article
High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
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- Nature, 2014, v. 513, n. 7516, p. 124, doi. 10.1038/nature13494
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- Publication type:
- Article
Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA.
- Published in:
- Nature, 2014, v. 512, n. 7513, p. 213, doi. 10.1038/nature13380
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- Publication type:
- Article
Structure of the human P2Y<sub>12</sub> receptor in complex with an antithrombotic drug.
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- Nature, 2014, v. 509, n. 7498, p. 115, doi. 10.1038/nature13083
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- Publication type:
- Article
The ensemble nature of allostery.
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- Nature, 2014, v. 508, n. 7496, p. 331, doi. 10.1038/nature13001
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- Publication type:
- Article