Works matching DE "ANTINEOPLASTIC agents"

Results: 5000

Ethyl β-carboline-3-carboxylate targets PRDX5/c-Jun axis for novel therapeutic strategy against cervical cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03306-4

By:

Xiao, Wan-Qiu;
Lee, Dong-Hun;
Kim, Hakjin;
Zhang, Hui-Na;
Feng, Yao-Yuan;
Jin, Ying-Hua;
Jin, Mei-Hua;
Han, Ying-Hao;
Kwon, Taeho;
Sun, Hu-Nan

Publication type:

Article

Beta cyclodextrin stabilized cupric oxide nanoparticles assisted thermal therapy for lung tumor and its effective in vitro anticancer activity.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96578-3

By:

Rajeeve, Anakha D.;
Veetil, Vyshnavi T.;
Palaniyappan, Sabarinathan;
Yamuna, Ramasamy;
Bhalla, Vishal

Publication type:

Article

Inhibition of human N myristoyltransferase 1 as a strategy to suppress cancer progression driven by myristoylation.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13529-8

By:

Alshahrani, Mohammed Merae

Publication type:

Article

Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11450-8

By:

Yuan, Fanli;
Wang, Hanliang;
Wang, Shuowang;
Wang, Jin;
Li, Junwei;
Shen, Yingying;
Lin, Jianjun;
Guo, Jufeng;
Cai, Lingzhi

Publication type:

Article

Synthesis and biological activity study of tanshinone I-pyridinium salt derivatives.

Published in:

Natural Products & Bioprospecting, 2025, v. 15, n. 1, p. 1, doi. 10.1007/s13659-025-00534-7

By:

Zhao, Huimin;
Wang, Yuyang;
Liu, Zining;
Lin, Lin;
Xiang, Jiasi;
Zhu, Zihao;
Yang, Xiongli;
Fang, Yongsheng;
Kong, Lingmei;
Li, Yan

Publication type:

Article

Correction: Severe thrombocytopenia induced by niraparib in ovarian cancer patients: a case report and literature review.

Published in:

2025

By:

Li, Jiajun;
Yang, Jiaxi;
Wang, Ying

Publication type:

Correction Notice

Severe thrombocytopenia induced by niraparib in ovarian cancer patients: a case report and literature review.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1542646

By:

Li, Jiajun;
Yang, Jiaxi;
Wang, Ying

Publication type:

Article

Cadonilimab as second-line therapy in immunotherapy-resistant squamous NSCLC: a case report and review.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1627147

By:

Qiu, Shuo;
Shi, Mingtao;
Chen, Zhiying;
Wang, Jing;
Cui, Huanliang;
Zhang, Yongchun

Publication type:

Article

Efficacy and safety of lenvatinib plus transarterial chemoembolization with or without programmed death-1 inhibitors in the treatment of intermediate or advanced hepatocellular carcinoma: a systematic review and meta-analysis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586914

By:

Lei, Yongfa;
Liang, Xiaotian;
Zhu, Hua;
Wang, Jin;
Zhang, Xiaochen;
Duan, Siliang;
Liang, Weiming

Publication type:

Article

Development of Starch-g-Oleic Acid, Gelatin and Alginate Based Magnetic Core-Shell Hydrogel Beads as Dual-Stimuli Responsive and Synergistic Tumour-Targeting Drug Delivery System.

Published in:

Journal of Polymers & the Environment, 2025, v. 33, n. 8, p. 3824, doi. 10.1007/s10924-025-03618-0

By:

Sampath, Buvana;
Charles, Julie

Publication type:

Article

Phytochemical Characterization of Persicaria longiseta Inflorescence Biomass and Its Biological Activities.

Published in:

BioResources, 2025, v. 20, n. 3, p. 6299, doi. 10.15376/biores.20.3.6299-6316

By:

Meganid, Abeer S.;
Amin, Mohamed A.

Publication type:

Article

SYNTHESIS OF NEW NITROGEN BRIDGED OXINDOLE AND ITS DERIVATIVES: A REVIEW OF RECENT PROGRESS IN BIOLOGICAL ACTIVITIES.

Published in:

Pharma Science Monitor, 2025, v. 16, n. 2, p. 1

By:

Korat, Haresh;
Gorasiya, Purvisha;
Kasar, Sujata;
Akbari, Bhavesh;
Korat, Rashmi;
Shah, Birenkumar

Publication type:

Article

Anticancer potential of 2,2′-bipyridine hydroxamic acid derivatives in head and neck cancer therapy.

Published in:

Journal of Computer-Aided Molecular Design, 2025, v. 39, n. 1, p. 1, doi. 10.1007/s10822-025-00640-1

By:

Shetty, Manasa Gangadhar;
Dey, Bipasa;
Pai, Padmini;
Sundara, Babitha Kampa;
Satyamoorthy, Kapaettu;
Oruganti, Srinivas;
Nayak, Usha Yogendra;
Ashwini, T.

Publication type:

Article

Chelidonine inhibits melanoma cell malignancy by inactivating TLR4/NF-κB and PI3K/AKT signaling pathways.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 4, p. 509, doi. 10.4196/kjpp.24.383

By:

Yu Zhou;
Han Han;
Peng Li;
Wei Wei

Publication type:

Article

Wogonin inhibits radiation-induced DNA damage repair in hepatocellular carcinoma cells by upregulating p21.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 4, p. 419, doi. 10.4196/kjpp.24.213

By:

Xiao Xu;
Yonghong Qian;
Shusheng Zhu;
Hu Tian;
Pingping Zhai;
Shimin Zhu;
Jingjing Wang;
Lei Xie;
Songbing Qin

Publication type:

Article

Discovery of novel and potent celastrol derivatives as PRDX1 inhibitors for cancer therapy through structure-based virtual screening.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1625604

By:

Guan, Lixia;
Geng, Yifei;
Wang, Yuting;
Niu, Miao-Miao;
Shi, Kun

Publication type:

Article

Dual PI3K/mTOR inhibitor NVP-BEZ235 induces cell cycle arrest via autophagy mediated protein degradation of RPL19 in nephroblastoma cell.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588722

By:

Gao, Yan;
Xing, Xinran;
Cai, Ruizhi;
Liu, Dong;
Feng, Qili;
Luo, Jiaqi;
Zhu, Yongzhao;
Su, Zeli

Publication type:

Article

SLFN11: a pan-cancer biomarker for DNA-targeted drugs sensitivity and therapeutic strategy guidance.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1582738

By:

Zhou, Kunzhong;
Li, Yuewen;
Wang, Weifang;
Chen, Yilin;
Qian, Bingyan;
Liang, Yiteng;
Li, Hongmei;
Xu, Ruiting;
Zhuang, Li

Publication type:

Article

Fabrication, biodistribution, and toxicological evaluation of mesoporous silica nanoparticles based on preclinical studies intended for cancer therapy: A review.

Published in:

Journal of Applied Pharmaceutical Science, 2025, v. 15, n. 7, p. 1, doi. 10.7324/JAPS.2025.220858

By:

Esa, Muhammad;
Kaewpaiboon, Sunisa;
Srichana, Teerapol

Publication type:

Article

dentifying Anti-cancer Effects and Exploring the Mechanism of an MPS1/TTK Inhibitor in Gastric Cancer.

Published in:

Cancer Research & Treatment, 2025, v. 57, n. 3, p. 803, doi. 10.4143/crt.2024.780

By:

Kim, Eunseo;
Kwon, Woo Sun;
Kim, Tae Soo;
Hwang, Jihyun;
Kim, Sunghwan;
Rha, Sun Young

Publication type:

Article

Fraction of Cancer Attributable to Carcinogenic Drugs in Korea from 2015 to 2030.

Published in:

Cancer Research & Treatment, 2025, v. 57, n. 3, p. 635, doi. 10.4143/crt.2024.644

By:

Lim, Woojin;
Sung, Soseul;
Hong, Youjin;
Moon, Sungji;
Lee, Sangjun;
Kim, Kyungsik;
Lee, Jung Eun;
Kim, Inah;
Ko, Kwang-Pil;
Park, Sue K.

Publication type:

Article

The Histone Deacetylase Inhibitor Entinostat Mediates HER2 Downregulation in Gastric Cancer, Providing the Basis for Its Particular Efficacy in HER2-Amplified Tumors and in Combination Therapies.

Published in:

Cancer Research & Treatment, 2025, v. 57, n. 3, p. 781, doi. 10.4143/crt.2024.546

By:

Zenz, Tamara;
Jenke, Robert;
Thieme, René;
Kahl, Tim;
Borchardt, Hannes;
Gockel, Ines;
Hansen, Finn K.;
Aigner, Achim;
Büch, Thomas R. H.

Publication type:

Article

Phytoextract-mediated Cupper nanoparticles via Acacia saligna: synthesis, characterization and in vitro anticancer and apoptosis inducing effects.

Published in:

Bioresources & Bioprocessing, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40643-025-00918-0

By:

Abdullah, Fuad O.

Publication type:

Article

Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models.

Published in:

Science Translational Medicine, 2025, v. 17, n. 810, p. 1, doi. 10.1126/scitranslmed.adn5400

By:

Zhou, Xinyue;
Moreira, Steven;
Restelli, Cecilia;
Wang, Hong;
Jahangiri, Soheil;
Aryal, Sajesan;
Tsao, Emily;
Zhang, Pengcheng;
Niu, Mingming;
Kumar, Harish;
Balde, Zaldy;
Vujovic, Ana;
Liu, Lina;
Wong, Nicholas;
Arruda, Andrea;
Minden, Mark D.;
Zhou, Yang;
Ravi, Bhatia;
Qi, Jun;
Li, Chunliang

Publication type:

Article

Ipatasertib combined with non-taxane chemotherapy for patients with previously treated advanced triple-negative breast cancer: the PATHFINDER phase IIa trial.

Published in:

Breast Cancer Research, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s13058-025-02089-4

By:

López-Miranda, Elena;
Pérez-García, Jose Manuel;
Gión, María;
Ribelles, Nuria;
Cortez-Castedo, Patricia;
Alonso-Romero, José Luis;
García, María Martínez;
González-Santiago, Santiago;
Bermejo, Begoña;
Morales, Serafín;
Carañana, Vicente;
Garrigós, Laia;
Fernández-Pinto, Melissa;
García-Vicente, Silvia;
Garcia-Sanz, Alicia;
Mena-Molina, Arnau;
Boix, Olga;
Alcalá-López, Daniel;
Llombart-Cussac, Antonio;
Cortés, Javier

Publication type:

Article

In vitro Evaluation of the Combinatory Antibacterial and Antiproliferative Effects of Ciprofloxacin and Curcumin–Quercetin Mixture.

Published in:

Applied Biochemistry & Microbiology, 2025, v. 61, n. 4, p. 711, doi. 10.1134/S0003683824608060

By:

Güran, M.;
Altundağ, E. M.;
Şanlıtürk, G.;
Ustürk, S.

Publication type:

Article

Hemorrhagic Gastropathy From Paclitaxel-Carboplatin Combination Chemotherapy.

Published in:

ACG Case Reports Journal, 2025, v. 12, n. 9, p. 1, doi. 10.14309/crj.0000000000001780

By:

Onyirioha, Kristeen;
Balakrishnan, Maya

Publication type:

Article

IncRNA 编码产物在癌症应用的研究进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 7, p. 1715, doi. 10.3969/j.issn.1009-5519.2025.07.038

By:

邢佳妮;
张瑞;
梁枫

Publication type:

Article

Ivabradine induces RAD51 degradation, potentiating PARP inhibitor efficacy in non-germline BRCA pathogenic variant triple-negative breast cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06902-8

By:

Tsoi, Ho;
Leung, George Man Hong;
Man, Ellen Pui Sum;
You, Chan Ping;
Cheung, Koei Ho Lam;
Chan, Kelvin Yuen Kwong;
Gong, Chun;
Huen, Michael Shing Yan;
Khoo, Ui Soon

Publication type:

Article

DrugBERT: a BERT-based approach integrating LDA topic embedding and efficacy-aware mechanism for predicting anti-tumor drug efficacy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06795-7

By:

Zhu, Weiwei;
Jiang, Xiaodong;
Zhang, Lei;
Zhou, Peng;
Xie, Xinping;
Wang, Hongqiang

Publication type:

Article

Enhanced homing and efficacy of HER2-CAR T cells via CXCR5/CCR6 co-expression for HER2-positive NSCLC.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06866-9

By:

Hu, Xiaoyuan;
Ge, Chunlei;
Huang, Caixiu;
He, Dan;
Yao, Xiaoxuan;
Cheng, Jiaxing;
Guo, Jiyin;
Li, Ke;
Ye, Yunshan;
Li, Li;
Xia, Jianchuan;
Li, Tao;
Yao, Hong

Publication type:

Article

Synergistic anticancer effect of CDRI-08 and abiraterone acetate against castration resistant prostate cancer targeting PI3K/Akt pathway.

Published in:

Iranian Journal of Basic Medical Sciences, 2025, v. 28, n. 9, p. 1163, doi. 10.22038/ijbms.2025.85330.18441

By:

Jonnalagadda, Bhavana;
Arockiasamy, Sumathy

Publication type:

Article

Development of some 1,2,3-triazole-based complexes incorporating hydroxy and acetamide groups: Synthesis, characterization, DFT calculation, and biological screening supported by molecular docking approach.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 7, p. 1, doi. 10.25259/AJC_162_2024

By:

Qasem, Hamza A.

Publication type:

Article

Integrated screening of Indonesian marine natural products as anticancer candidates through ADMET-clustering analysis, molecular docking, and molecular dynamics simulation.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 6, p. 1, doi. 10.25259/AJC_84_2024

By:

Rasyid, Herlina;
Maharani, Rani;
Kusumawati, Yuly;
Kartikowati, Christina Wahyu;
Umaningrum, Dewi;
Syahrir, Nur Hilal A;
Musa, Bulkis;
Siswanto, Siswanto;
Bahrun, Bahrun;
Massi, Muhammad Nasrum

Publication type:

Article

Exploring the therapeutic potential of benzodioxane carboxylic acid-based hydrazones: Structural, computational, and biological insights.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 6, p. 1, doi. 10.25259/AJC_129_2025

By:

Rafique, Aisha;
Sajid Hamid Akash, Muhammad;
Rehman, Kanwal

Publication type:

Article

Designing and immobilizing gold nanoparticles over a lignosulfonate/starch composite for Suzuki-Miyaura coupling reactions, and investigation of its anti-pancreatic and anti-hepatitis cancer effects.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 5, p. 1, doi. 10.25259/AJC_204_2025

By:

Zhang, Hui;
Liu, Aixiang;
El-Kott, Attalla F.;
Hu, Yong;
Zhang, Mingyi;
Alshehri, Ali S.;
Morsy, Kareem;
Feng, Xielin;
Hou, Guimin

Publication type:

Article

Synthesis of new pyrazine-thiazole analogs: Molecular modeling, anticancer activity, and pharmacokinetic properties.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 3, p. 1, doi. 10.25259/AJC_300_2024

By:

Alomari, Khadra B.;
Siddiq, Hind A.;
Qurban, Jihan;
Alrefaei, Abdulmajeed F.;
Bayazeed, Abrar;
Alshammari, Nawaa Ali H.;
Katouah, Hanadi A.;
El-Metwaly, Nashwa M.

Publication type:

Article

Integrated HTS2, UPLC-MS/MS, and network pharmacology identifies Bruceae Fructus waste as potential source of flavonoids and quassinoids for inhibiting breast cancer.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 3, p. 1, doi. 10.25259/AJC_23_2024

By:

Yu, Xiankuo;
Xiang, Lei;
An, Jun;
Li, Shengrong;
Hu, Chao;
Gui, Yu;
Wang, Yumei;
Bao, Xilinqiqige;
Wang, Dong

Publication type:

Article

Design, synthesis, biological evaluation, and in silico study of quinazoline-based dual inhibitors targeting EGFR and VEGFR-2 for cancer therapy.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 3, p. 1, doi. 10.25259/AJC_6_2025

By:

Altharawi, Ali;
Alossaimi, Manal A.;
Aldakhil, Taibah

Publication type:

Article

Investigating chlorothiophene-based chalcones as anticancer agents: Synthesis, biological evaluation, and computational insight via the p53-targeted pathway.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 2, p. 1, doi. 10.25259/AJC_31_2024

By:

Wulan, Fia Fathiana;
Astuti, Endang;
Prasetyo, Niko;
Kumar, Naresh;
Wahyuningsih, Tutik Dwi

Publication type:

Article

Inhibition of TFF3 improves the infiltration and function of CD8<sup>+</sup> T cells by downregulating the expression of PD-L1 in colorectal cancer.

Published in:

International Journal of Colorectal Disease, 2025, v. 40, n. 1, p. 1, doi. 10.1007/s00384-025-04964-0

By:

Pan, Xiaoxue;
Li, Jichang;
Zhu, Jing;
Wang, Xin;
Liu, Yucun;
Chen, Shanwen;
Wang, Pengyuan

Publication type:

Article

Trastuzumab plus lapatinib or chemotherapy in patients with HER2-overexpressed advanced breast cancer: a randomized, phase II trial (GIM12-TYPHER).

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf200

By:

Angelis, Carmine De;
Pagliuca, Martina;
Magnolfi, Emanuela;
Mansutti, Mauro;
Ballatore, Zelmira;
Laurentiis, Michelino De;
Bordonaro, Roberto;
Leonardi, Vita;
Bruzzese, Dario;
Caputo, Roberta;
Mosconi, Anna Maria;
Cinieri, Saverio;
Fabi, Alessandra;
Mastro, Lucia Del;
Puglisi, Fabio;
Placido, Sabino De;
Giuliano, Mario;
Arpino, Grazia

Publication type:

Article

Phase II study of avelumab and trastuzumab with FOLFOX chemotherapy in previously untreated HER2-amplified metastatic gastroesophageal adenocarcinoma.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf195

By:

Lee, Michael S;
Chao, Joseph;
Mulcahy, Mary F;
Kasi, Pashtoon M;
Alistar, Angela T;
Mukherjee, Sarbajit;
Akce, Mehmet;
Moore, Dominic T;
McRee, Autumn J;
Somasundaram, Ashwin

Publication type:

Article

New tool in the toolbox: patient selection for zolbetuximab in advanced treatment-naïve gastric/gastroesophageal junction adenocarcinoma.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf185

By:

Grewal, Udhayvir S;
Brown, Timothy J

Publication type:

Article

Long-term safety analysis of pooled data for tislelizumab as monotherapy or in combination with chemotherapy in patients with advanced cancers.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf177

By:

Zhou, Caicun;
Huang, Rose;
Yuan, Yuan;
Schnell, Patrick;
Wu, John;
Kadva, Alysha;
Mehmeti, Jola;
Ajani, Jaffer

Publication type:

Article

Patient-reported tolerance of 90 days of preoperative endocrine therapy: results from the preoperative window of endocrine therapy to inform radiation therapy decisions trial.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf172

By:

Millard, Trish;
Turkheimer, Lena M;
Schlefman, Jenna;
Petroni, Gina R;
Brighton, David;
Showalter, Shayna L

Publication type:

Article

Cartoon: multicenter prospective observational study of Cardiovascular Toxicity of Trifluridine/Tipiracil in metastatic colorectal cancer.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf178

By:

Leone, Francesco;
Fiamma, Valeria;
Crivelli, Francesca;
Paris, Myriam Katja;
Forti, Laura Giovanna;
Brizzi, Maria Pia;
Sperti, Elisa;
Laface, Rosa;
Tober, Nastassja;
Salerno, Flavio;
Traverso, Elena Silvia;
Parlagreco, Elena;
Nepote, Alessandro;
Giuli, Angelo;
Bonessio, Elisa;
Nicolì, Elena;
Bertola, Benedetta;
Montagnani, Francesco

Publication type:

Article

First-line treatment with HDACis plus tislelizumab combined with chemotherapy in advanced NSCLC: a single-arm phase II study.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf155

By:

Wang, Lijie;
Gao, Ming;
Wang, Ting;
Cui, Pengfei;
Chen, Guangying;
Han, Xiao;
Ma, Zhiqiang;
Yang, Wenyu;
Jing, Fangfang;
Ma, Junxun;
Zhang, Fan;
Tao, Haitao;
Hu, Yi

Publication type:

Article

Immune-mediated adverse events in the randomized phase 3 TOPAZ-1 study of durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf148

By:

Antonuzzo, Lorenzo;
Takahashi, Hidenori;
Park, Joon Oh;
Sookprasert, Aumkhae;
Gillmore, Roopinder;
Yang, Sheng-Shun;
Cundom, Juan;
Petrova, Mila;
Vaccaro, Gina;
Holmblad, Marielle;
Żotkiewicz, Magdalena;
Wang, Julie;
Rokutanda, Nana;
Oh, Do-Youn

Publication type:

Article

Colorectal cancer in pregnancy: case discussions and real-world data as well as literature review on current knowledge.

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf097

By:

Poulgrain, Suzanne;
Gibbons, Ted;
O'Leary, Cian;
Feng, Sophie;
Jain, Vikram;
O'Leary, Connor Gerard

Publication type:

Article