Works matching DE "TARGETED drug delivery"

Results: 5000

Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1053, doi. 10.3390/biomedicines13051053

By:

Otoda, Toshiki;
Aihara, Ken-ichi;
Takayama, Tadateru

Publication type:

Article

Design, Fabrication, and Experimental Validation of Optical Microbots.

Published in:

Actuators, 2025, v. 14, n. 5, p. 229, doi. 10.3390/act14050229

By:

Konara, Menaka;
Pokharel, Mishal;
Sagar, Md Mainuddin;
Kim, Yeongjin;
Park, Kihan

Publication type:

Article

The Role of Selected Flavonoids in Modulating Neuroinflammation in Alzheimer's Disease: Mechanisms and Therapeutic Potential.

Published in:

Brain Sciences (2076-3425), 2025, v. 15, n. 5, p. 485, doi. 10.3390/brainsci15050485

By:

Kruszka, Joanna;
Martyński, Jakub;
Szewczyk-Golec, Karolina;
Woźniak, Alina;
Nuszkiewicz, Jarosław

Publication type:

Article

Biosynthesis of silver nanoparticles from plant extracts: a comprehensive review focused on anticancer therapy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1600347

By:

Pandey, Pratibha;
Lakhanpal, Sorabh;
Bishoyi, Ashok Kumar;
Jyothi, S. Renuka;
Mishra, Swati;
Verma, Meenakshi;
Singh, Ajay;
Alam, Mir Waqas;
Rab, Safia Obaidur;
Saeed, Mohd;
Khan, Fahad

Publication type:

Article

Nanocarrier-based targeted drug delivery for Alzheimer's disease: addressing neuroinflammation and enhancing clinical translation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1591438

By:

Wang, Kang;
Yang, Rongying;
Li, Jing;
Wang, Haitao;
Wan, Li;
He, Jiale

Publication type:

Article

Next-Generation Hydrogel Design: Computational Advances in Synthesis, Characterization, and Biomedical Applications.

Published in:

Polymers (20734360), 2025, v. 17, n. 10, p. 1373, doi. 10.3390/polym17101373

By:

Fareed, Muhammad Mazhar;
Shityakov, Sergey

Publication type:

Article

Targeted Drug Delivery to the Spleen and Its Implications for the Prevention and Treatment of Cancer.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 651, doi. 10.3390/pharmaceutics17050651

By:

Khalil, Ikramy A.;
Faheem, Ahmed;
El-Tanani, Mohamed

Publication type:

Article

Ocular Drug Delivery: Emerging Approaches and Advances.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 599, doi. 10.3390/pharmaceutics17050599

By:

Gade, Shilpkala;
So, Yin;
Mishra, Deepakkumar;
Baviskar, Shubhamkumar M.;
Assiri, Ahmad A.;
Glover, Katie;
Sheshala, Ravi;
Vora, Lalitkumar K.;
Thakur, Raghu Raj Singh

Publication type:

Article

An Inhaled Nanoemulsion Encapsulating a Herbal Drug for Non-Small Cell Lung Cancer (NSCLC) Treatment.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 540, doi. 10.3390/pharmaceutics17050540

By:

Quadros, Mural;
Goyal, Mimansa;
Chauhan, Gautam;
Gadhave, Dnyandev;
Gupta, Vivek

Publication type:

Article

A Novel Squalenoylated Temozolomide Nanoparticle with Long Circulating Properties Reverses Drug Resistance in Glioblastoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4723, doi. 10.3390/ijms26104723

By:

Feng, Jiao;
Wen, Chengyong;
Zhang, Xiao;
Zhu, Xiaolong;
Ma, Mengmeng;
Zhao, Xiaohong;
Sui, Xinbing

Publication type:

Article

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 22, p. 1, doi. 10.1002/adfm.202425394

By:

Dwivedy, Abhisek;
Baskaran, Dhyanesh;
Sharma, Gaurav;
Hong, Wei;
Gandavadi, Dhanush;
Krissanaprasit, Abhichart;
Han, Joonsu;
Liu, Yusheng;
Zimmers, Zack;
Mafokwane, Tshepo;
Hayah, Ichrak;
Chauhan, Neha;
Zheng, Mengxi;
Yao, Sherwood;
Fraser, Keith;
Decker, John S.;
Jin, Xiaohe;
Wang, Hua;
Friedman, Adam D.;
Wang, Xing

Publication type:

Article

Surface-modified liposomal in-situ nasal gel enhances brain targeting of berberine hydrochloride for Alzheimer's therapy: optimization and in vivo studies.

Published in:

Journal of Liposome Research, 2025, v. 35, n. 2, p. 135, doi. 10.1080/08982104.2024.2431908

By:

Bahndare, Sejal;
Mathure, Dyandevi;
Ranpise, Hemantkumar;
Salunke, Malati;
Awasthi, Rajendra

Publication type:

Article

Silver Nanoparticles for Biosensing and Drug Delivery: A Mechanical Study on DNA Interaction.

Published in:

Biosensors (2079-6374), 2025, v. 15, n. 5, p. 331, doi. 10.3390/bios15050331

By:

Nemčeková, Katarína;
Dudoňová, Patrícia;
Holka, Tomáš;
Balážová, Sabína;
Hornychová, Michaela;
Szebellaiová, Viktória;
Naumowicz, Monika;
Gemeiner, Pavol;
Mackuľak, Tomáš;
Gál, Miroslav;
Svitková, Veronika

Publication type:

Article

Targeting the Ophthalmic Diseases Using Extracellular Vesicles 'Exosomes': Current Insights on Their Clinical Approval and Present Trials.

Published in:

2025

By:

Hanxiang Yu;
Jinsong Wu;
Gaoxiang Pan

Publication type:

Literature Review

Energetic dissection of Gleevec's selectivity toward human tyrosine kinases.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 10, p. 848, doi. 10.1038/nsmb.2891

By:

Agafonov, Roman V;
Wilson, Christopher;
Otten, Renee;
Buosi, Vanessa;
Kern, Dorothee

Publication type:

Article

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 11, p. 1204, doi. 10.1038/nsmb.2139

By:

Cheng, Zhihong;
Biechele, Travis;
Wei, Zhiyi;
Morrone, Seamus;
Moon, Randall T;
Wang, Liguo;
Xu, Wenqing

Publication type:

Article

Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 846, doi. 10.1038/nsmb.2068

By:

Kosloff, Mickey;
Travis, Amanda M.;
Bosch, Dustin E.;
Siderovski, David P.;
Arshavsky, Vadim Y.

Publication type:

Article

Divide and conquer: the E2 active site.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 6, p. 474, doi. 10.1038/nsmb0606-474

By:

Knipscheer, Puck;
Sixma, Titia K

Publication type:

Article

Glycogen Synthase Kinase-3: A New Therapeutic Target in Mood Disorders.

Published in:

Klinik Psikofarmakoloji Bulteni, 2013, v. 23, n. 2, p. 193, doi. 10.5455/bcp.20130624022007

By:

Aricioglu, Feyza;
Gumru, Salih

Publication type:

Article

Novel Targets for Development of Drugs for Treating Schizophrenia: Focus on Glycine, D-Serine and Nitric Oxide.

Published in:

Klinik Psikofarmakoloji Bulteni, 2013, v. 23, n. 2, p. 129, doi. 10.5455/bcp.20130629042437

By:

Dhami, Kamaldeep;
MacKay, Marnie;
Maia-de-Oliveira, Joao Paulo;
Hallak, Jaime;
Todd, Kathryn;
Baker, Glen;
Dursun, Serdar

Publication type:

Article

Recent advance in functionalized mesoporous silica nanoparticles with stimuli-responsive polymer brush for controlled drug delivery.

Published in:

Soft Materials, 2022, v. 20, n. 3, p. 364, doi. 10.1080/1539445X.2022.2028831

By:

Alfhaid, Latifah Hamad K.

Publication type:

Article

Development of Peptide Conjugated Chlorogenic Acid Nanoassemblies for Targeting Tumorigenic Cells.

Published in:

Soft Materials, 2015, v. 13, n. 3, p. 150, doi. 10.1080/1539445X.2015.1045076

By:

Sortino, Rachel M.;
Romanelli, Steven M.;
Knoll, Grant A.;
Banerjee, Ipsita A.

Publication type:

Article

The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 7, p. 482, doi. 10.1038/nrmicro3046

By:

Bartenschlager, Ralf;
Lohmann, Volker;
Penin, Francois

Publication type:

Article

Riboswitching off bacterial growth.

Published in:

Nature Reviews Microbiology, 2007, v. 5, n. 2, p. 88, doi. 10.1038/nrmicro1603

By:

Owens, Joanna

Publication type:

Article

Is IL-10 a Good Target to Inhibit Choroidal Neovascularisation in Age-Related Macular Disease?

Published in:

2006

By:

Lightman, Sue;
Calder, Virginia

Publication type:

Editorial

Relationship between serum progesterone (P) levels and pregnancy outcome: lessons from artificial cycles when using vaginal natural micronized progesterone.

Published in:

2020

By:

Labarta, Elena

Publication type:

Letter

The role of companion animal models in radiopharmaceutical development and translation.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 2, p. 165, doi. 10.1111/vco.12969

By:

Maitz, Charles A.;
Bryan, Jeffrey N.

Publication type:

Article

A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 3, p. 324, doi. 10.1111/vco.12551

By:

Khammanivong, Ali;
Saha, Jhuma;
Spartz, Angela K.;
Sorenson, Brent S.;
Bush, Alexander G.;
Korpela, Derek M.;
Gopalakrishnan, Raj;
Jonnalagadda, Shirisha;
Mereddy, Venkatram R.;
O'Brien, Timothy D.;
Drewes, Lester R.;
Dickerson, Erin B.

Publication type:

Article

p62/SQSTM1 expression in canine mammary tumours: Evolutionary notes.

Published in:

Veterinary & Comparative Oncology, 2019, v. 17, n. 4, p. 570, doi. 10.1111/vco.12523

By:

Mariotti, Francesca;
Magi, Gian Enrico;
Gavazza, Alessandra;
Vincenzetti, Silvia;
Komissarov, Andrey;
Shneider, Alex;
Venanzi, Franco Maria

Publication type:

Article

Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy.

Published in:

Veterinary & Comparative Oncology, 2012, v. 10, n. 3, p. 163, doi. 10.1111/j.1476-5829.2012.00342.x

By:

Bavcar, S.;
Argyle, D. J.

Publication type:

Article

Domainex Expands Breast Cancer Drug Discovery Deal with ICR.

Published in:

Bio-IT World, 2010, v. 9, n. 3, p. D5

By:

DAVIES, KEVIN

Publication type:

Article

Rhythm and Blues: The Case for Allosteric Modulators.

Published in:

Bio-IT World, 2010, v. 9, n. 3, p. 46

By:

DAVIES, KEVIN

Publication type:

Article

Molecular Snipers Set Sights on Multiple Targets.

Published in:

Bio-IT World, 2004, v. 3, n. 2, p. 18

By:

Branca, Malorye A.

Publication type:

Article

Targeted Medicine via Molecular Diagnostics.

Published in:

Bio-IT World, 2003, v. 2, n. 11, p. 52

By:

Ordoñez, Kathy

Publication type:

Article

Dual‐Stimuli‐Activatable Hybrid Prodrug for the Self‐Immolative Delivery of an Anticancer Agent and Hydrogen Sulfide with Turn‐On Fluorescence.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 66, p. 1, doi. 10.1002/chem.202302197

By:

Sufian, Abu;
Badirujjaman, Md.;
Barman, Pallavi;
Bhabak, Krishna P.

Publication type:

Article

Controlling Morphologies of Redox‐Responsive Polymeric Nanocarriers for a Smart Drug Delivery System.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 34, p. 1, doi. 10.1002/chem.202300594

By:

Lee, Chae Gyu;
Kwon, Tae‐Hyuk

Publication type:

Article

Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate‐Caged Guanidine Lipid.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 46, p. 1, doi. 10.1002/chem.202201057

By:

Lou, Jinchao;
Qualls, Megan L.;
Hudson, Macy M.;
McBee, Dillon P.;
Baccile, Joshua A.;
Best, Michael D.

Publication type:

Article

Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic Development.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 5, p. 1487, doi. 10.1002/chem.201905385

By:

Buckton, Laura K.;
Rahimi, Marwa N.;
McAlpine, Shelli R.

Publication type:

Article

Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction**.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 64, p. 14585, doi. 10.1002/chem.202002250

By:

Mancini, Federica;
Unver, M. Yagiz;
Elgaher, Walid A. M.;
Jumde, Varsha R.;
Alhayek, Alaa;
Lukat, Peer;
Herrmann, Jennifer;
Witte, Martin D.;
Köck, Matthias;
Blankenfeldt, Wulf;
Müller, Rolf;
Hirsch, Anna K. H.

Publication type:

Article

Alternating Magnetic Field Controlled Targeted Drug Delivery Based on Graphene Oxide‐Grafted Nanosupramolecules.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 60, p. 13698, doi. 10.1002/chem.202003328

By:

Zhang, Bing;
Yu, Qilin;
Liu, Yu

Publication type:

Article

Highly Selective Binding and Inhibition of Pyr‐His‐Pro‐NH<sub>2</sub> (TRH) Function using a Polypyridinyl Macrocyclic Receptor with an Amphiphilic Cavity.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 43, p. 9466, doi. 10.1002/chem.202000888

By:

Hou, Chao‐Ping;
Yang, Jian;
Zhang, Lei;
Ma, Zhen‐Hua;
Li, Qian;
Xiang, Jun‐Feng;
Gong, Han‐Yuan

Publication type:

Article

Nanobody‐Ferritin Conjugate for Targeted Photodynamic Therapy.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 33, p. 7442, doi. 10.1002/chem.202000075

By:

Liu, Manman;
Zhu, Yang;
Wu, Tiantian;
Cheng, Junjie;
Liu, Yangzhong

Publication type:

Article

Magnetic Hybrid Wax Nanocomposites as Externally Controlled Theranostic Vehicles: High MRI Enhancement and Synergistic Magnetically Assisted Thermo/Chemo Therapy.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 20, p. 4531, doi. 10.1002/chem.201904709

By:

Moura, Carolina L.;
Gallo, Juan;
García‐Hevia, Lorena;
Pessoa, Otília D. L.;
Ricardo, Nágila M. P. S.;
Bañobre‐López, Manuel

Publication type:

Article

Titelbild: Autocrine-Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries (Angew. Chem. 32/2016).

Published in:

Angewandte Chemie, 2016, v. 128, n. 32, p. 9245, doi. 10.1002/ange.201604909

By:

Zhang, Hongkai;
Du, Mingjuan;
Xie, Jia;
Liu, Xiao;
Sun, Jingying;
Wang, Wei;
Xin, Xiu;
Possani, Lourival D.;
Yea, Kyungmoo;
Lerner, Richard A.

Publication type:

Article

A Drug-Free Tumor Therapy Strategy: Cancer-Cell-Targeting Calcification.

Published in:

Angewandte Chemie, 2016, v. 128, n. 17, p. 5311, doi. 10.1002/ange.201601364

By:

Zhao, Ruibo;
Wang, Ben;
Yang, Xinyan;
Xiao, Yun;
Wang, Xiaoyu;
Shao, Changyu;
Tang, Ruikang

Publication type:

Article

Organometallic Rhenium Complexes Divert Doxorubicin to the Mitochondria.

Published in:

Angewandte Chemie, 2016, v. 128, n. 8, p. 2842, doi. 10.1002/ange.201511432

By:

Imstepf, Sebastian;
Pierroz, Vanessa;
Rubbiani, Riccardo;
Felber, Michael;
Fox, Thomas;
Gasser, Gilles;
Alberto, Roger

Publication type:

Article

Multidimensional De Novo Design Reveals 5-HT<sub>2B</sub> Receptor-Selective Ligands.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1571, doi. 10.1002/ange.201410201

By:

Rodrigues, Tiago;
Hauser, Nadine;
Reker, Daniel;
Reutlinger, Michael;
Wunderlin, Tiffany;
Hamon, Jacques;
Koch, Guido;
Schneider, Gisbert

Publication type:

Article

Multitarget Drug Discovery for Alzheimer's Disease: Triazinones as BACE-1 and GSK-3β Inhibitors.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1598, doi. 10.1002/ange.201410456

By:

Prati, Federica;
De Simone, Angela;
Bisignano, Paola;
Armirotti, Andrea;
Summa, Maria;
Pizzirani, Daniela;
Scarpelli, Rita;
Perez, Daniel I.;
Andrisano, Vincenza;
Perez-Castillo, Ana;
Monti, Barbara;
Massenzio, Francesca;
Polito, Letizia;
Racchi, Marco;
Favia, Angelo D.;
Bottegoni, Giovanni;
Martinez, Ana;
Bolognesi, Maria Laura;
Cavalli, Andrea

Publication type:

Article

Mitochondria-Targeted Cancer Therapy Using a Light-Up Probe with Aggregation-Induced-Emission Characteristics.

Published in:

Angewandte Chemie, 2014, v. 126, n. 51, p. 14449, doi. 10.1002/ange.201408897

By:

Hu, Qinglian;
Gao, Meng;
Feng, Guangxue;
Liu, Bin

Publication type:

Article

Organocatalytic and Scalable Synthesis of the Anti-Influenza Drugs Zanamivir, Laninamivir, and CS-8958.

Published in:

Angewandte Chemie, 2014, v. 126, n. 50, p. 14105, doi. 10.1002/ange.201408138

By:

Tian, Junshan;
Zhong, Jiankang;
Li, Yunsheng;
Ma, Dawei

Publication type:

Article