Works matching DE "INSULIN receptors"

Results: 2593

GLP-1R in diabetes mellitus: from basic discovery to therapeutics development.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1610512

By:

Li, Shujun;
Huang, Nanqu;
Wang, Mei;
Huang, Wendi;
Luo, Yong;
Huang, Juan

Publication type:

Article

BACE1 Inhibition Protects Against Type 2 Diabetes Mellitus by Restoring Insulin Receptor in Mice.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5100, doi. 10.3390/ijms26115100

By:

Lin, Tingting;
Liang, Ting;
Shen, Yong;
Gao, Feng

Publication type:

Article

Association of Some Hormones with Anthropometric Measurements in Women.

Published in:

Iraqi Journal of Science, 2025, v. 66, n. 4, p. 1451, doi. 10.24996/ijs.2025.66.4.5

By:

Mohammad, Fatima A.;
Abdulkareem, Nadia Ghassan

Publication type:

Article

Antidiabetic GLP-1 Receptor Agonists Have Neuroprotective Properties in Experimental Animal Models of Alzheimer's Disease.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 614, doi. 10.3390/ph18050614

By:

Urkon, Melinda;
Ferencz, Elek;
Szász, József Attila;
Szabo, Monica Iudita Maria;
Orbán-Kis, Károly;
Szatmári, Szabolcs;
Nagy, Előd Ernő

Publication type:

Article

Interaction Between Dietary Fiber Intake and MTNR1B rs10830963 Polymorphism on Glycemic Profiles in Young Brazilian Adults.

Published in:

Genes, 2025, v. 16, n. 5, p. 497, doi. 10.3390/genes16050497

By:

Lima, Ana Carolina da Silva;
Cruvinel, Nathália Teixeira;
Silva, Nara Rubia da;
Mendes, Marcela Moraes;
Duarte, Amélia Cristina Stival;
Coelho, Alexandre Siqueira Guedes;
Vimaleswaran, Karani S.;
Horst, Maria Aderuza

Publication type:

Article

PTEN is a protein tyrosine phosphatase for IRS1.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 522, doi. 10.1038/nsmb.2828

By:

Shi, Yuji;
Wang, Junru;
Chandarlapaty, Sarat;
Cross, Justin;
Thompson, Craig;
Rosen, Neal;
Jiang, Xuejun

Publication type:

Article

Grb-ing hold of insulin signaling.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 8, p. 803, doi. 10.1038/nsmb0809-803

By:

Ceccarelli, Derek F. J.;
Sicheri, Frank

Publication type:

Article

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 3, p. 251, doi. 10.1038/nsmb.1388

By:

Jinhua Wu;
Tseng, Yolanda D.;
Chong-Feng Xu;
Neubert, Thomas A.;
White, Morris F.;
Hubbard, Stevan R.

Publication type:

Article

When a domain is not a domain.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 3, p. 224, doi. 10.1038/nsmb0308-224

By:

Park, Sang Youn;
Shoelson, Steven E.

Publication type:

Article

Prevalence of the insulin receptor substrate-1(IRS-1) Gly972Arg and the insulin receptor substrate-2(IRS-2) Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women.

Published in:

Journal of Assisted Reproduction & Genetics, 2012, v. 29, n. 2, p. 195, doi. 10.1007/s10815-011-9693-7

By:

Rashidi, Batool;
Azizy, Leila;
Najmeddin, Farhad;
Azizi, Ebrahim

Publication type:

Article

Influence of gene variants related to calcium homeostasis on biochemical parameters of women with polycystic ovary syndrome.

Published in:

Journal of Assisted Reproduction & Genetics, 2011, v. 28, n. 3, p. 225, doi. 10.1007/s10815-010-9506-4

By:

Ranjzad, Fariba;
Mahban, Aidin;
Irani Shemirani, Atena;
Mahmoudi, Touraj;
Vahedi, Mohsen;
Nikzamir, Abdolrahim;
Zali, Mohammad

Publication type:

Article

Effects of silibinin on apoptosis and insulin secretion in rat RINm5F pancreatic β-cells.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 3, p. 201, doi. 10.1080/10520295.2022.2154840

By:

Mazraesefidi, Maryam;
Mahmoodi, Mehdi;
Hajizadeh, Mohammadreza

Publication type:

Article

Expression of IRS2 in the female reproductive system during the estrous cycle in mice.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 3, p. 187, doi. 10.1080/10520295.2022.2153167

By:

Wang, Zhongli;
Yi, Benyi;
Gan, Lijun;
Li, Xiuli;
Liu, Xiuxiu;
Lv, Qizhuang;
Yang, Lei

Publication type:

Article

Silibinin and ellagic acid increase the expression of insulin receptor substrate 1 protein in ultraviolet irradiated rat skin.

Published in:

Biotechnic & Histochemistry, 2020, v. 95, n. 8, p. 641, doi. 10.1080/10520295.2020.1753238

By:

Gorgisen, G.;
Ozkol, H.;
Tuluce, Y.;
Arslan, A.;
Ecer, Y.;
Keskin, S.;
Kaya, Z.;
Ragbetli, M C.

Publication type:

Article

Insulin receptor is expressed in normal canine mammary gland and benign adenomas but decreased in metastatic canine mammary carcinomas similar to human breast cancer R. Klopfleisch et al.

Published in:

Veterinary & Comparative Oncology, 2010, v. 8, n. 4, p. 293, doi. 10.1111/j.1476-5829.2009.00232.x

By:

Klopfleisch, R.;
Hvid, H.;
Klose, P.;
Da Costa, A.;
Gruber, A. D.

Publication type:

Article

IRS gene polymorphisms in Turkish patients with late-onset Alzheimer's disease.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10352-2

By:

Ozkan, Hulya;
Yildiz, Mustafa;
Ustundag, Ayten;
Kara, Ismail;
Guldiken, Baburhan;
Sut, Necdet;
Sipahi, Tammam

Publication type:

Article

The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na+/K+-ATPase.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09451-3

By:

Banjac, Katarina;
Obradovic, Milan;
Zafirovic, Sonja;
Essack, Magbubah;
Gluvic, Zoran;
Sunderic, Milos;
Nedic, Olgica;
Isenovic, Esma R.

Publication type:

Article

Insulin nucleation kinetics in an oscillatory flow-based platform: Protein crystallization as a highly reproducible separation process.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2024, v. 203, p. 453, doi. 10.1016/j.cherd.2024.01.057

By:

Ferreira, Joana;
Araújo, Sofia;
Ferreira, António;
Teixeira, José;
de Campos, João Moreira;
Rocha, Fernando;
Castro, Filipa

Publication type:

Article

Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells.

Published in:

Amino Acids, 2023, v. 55, n. 3, p. 413, doi. 10.1007/s00726-022-03230-9

By:

Matthews, Joseph J.;
Turner, Mark D.;
Santos, Livia;
Elliott-Sale, Kirsty J.;
Sale, Craig

Publication type:

Article

Insulin Receptor and Glucose Transporters in the Mammalian Cochlea.

Published in:

2019

By:

Huerzeler, Nathan;
Petkovic, Vesna;
Sekulic-Jablanovic, Marijana;
Kucharava, Krystsina;
Wright, Matthew B.;
Bodmer, Daniel;
Wright, Matthew B

Publication type:

journal article

Michael D. Waterfield.

Published in:

Biochemical Journal, 2023, v. 480, n. 18, p. 1475, doi. 10.1042/BCJ20230368

By:

Downward, Julian;
Parker, Peter J.;
Vanhaesebroeck, Bart

Publication type:

Article

Methylglyoxal induces multiple serine phosphorylation in insulin receptor substrate 1 via the TAK1–p38–mTORC1 signaling axis in adipocytes.

Published in:

Biochemical Journal, 2022, v. 479, n. 21, p. 2279, doi. 10.1042/BCJ20220271

By:

Su-Ping Ng;
Wataru Nomura;
Haruya Takahashi;
Kazuo Inoue;
Teruo Kawada;
Tsuyoshi Goto;
Yoshiharu Inoue

Publication type:

Article

Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells.

Published in:

Biochemical Journal, 2022, v. 479, n. 16, p. 1709, doi. 10.1042/BCJ20220184

By:

Murugesan, Gavuthami;
Prescott, Alan R.;
Toth, Rachel;
Campbell, David G.;
Wells, Claire M.;
MacKintosh, Carol

Publication type:

Article

GLUT4 On the move.

Published in:

Biochemical Journal, 2022, v. 479, n. 3, p. 445, doi. 10.1042/BCJ20210073

By:

Fazakerley, Daniel J.;
Koumanov, Francoise;
Holman, Geoffrey D.

Publication type:

Article

LMBD1 protein participates in cell mitosis by regulating microtubule assembly.

Published in:

Biochemical Journal, 2021, v. 478, n. 12, p. 2321, doi. 10.1042/BCJ20210070

By:

Chiao-Yin Sun;
Chang, Shin C.;
Hsiu-Po Wang;
Yu-Jung Lee;
Kuei-Hsiang Pan;
Chieh-Liang Lin;
Yu-Ting Hsieh;
Yng-Cun Ta;
Yau-Hung Chen;
Ming-Fu Chang

Publication type:

Article

The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α1-adrenergic receptors.

Published in:

Biochemical Journal, 2021, v. 478, n. 11, p. 2059, doi. 10.1042/BCJ20210144

By:

Meijles, Daniel N.;
Fuller, Stephen J.;
Cull, Joshua J.;
Alharbi, Hajed O.;
Cooper, Susanna T. E.;
Sugden, Peter H.;
Clerk, Angela

Publication type:

Article

Complexin-2 redistributes to the membrane of muscle cells in response to insulin and contributes to GLUT4 translocation.

Published in:

Biochemical Journal, 2021, v. 478, n. 2, p. 407, doi. 10.1042/BCJ20200542

By:

Pavarotti, Martin Alejandro;
Tokarz, Victoria;
Frendo-Cumbo, Scott;
Bilan, Philip J.;
Zhi Liu;
Zanni-Ruiz, Emilia;
Mayorga, Luis Segundo;
Klip, Amira

Publication type:

Article

Network-based comparison of temporal gene expression patterns.

Published in:

Bioinformatics, 2010, v. 26, n. 23, p. 2944, doi. 10.1093/bioinformatics/btq561

By:

Huang, Wei;
Cao, Xiaoyi;
Zhong, Sheng

Publication type:

Article

HT22 cell differentiation reduces insulin receptor levels.

Published in:

Pamukkale Medical Journal, 2024, v. 17, n. 1, p. 79, doi. 10.31362/patd.1338766

By:

Ata, Melek Tunç;
Altıntaş, Fatih

Publication type:

Article

Comparison of phytooestrogen-coumestrol and oestrone effects on the liver membranes insulin receptors in ovariectomized female rats.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1993, v. 51, n. 2, p. 219, doi. 10.1007/BF00198884

By:

Nogowski, L.;
Maćkowiak, P.;
Nowak, K.

Publication type:

Article

Cargo receptor Surf4 regulates endoplasmic reticulum export of proinsulin in pancreatic β-cells.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03417-6

By:

Saegusa, Keiko;
Matsunaga, Kohichi;
Maeda, Miharu;
Saito, Kota;
Izumi, Tetsuro;
Sato, Ken

Publication type:

Article

Rabson-Mendenhall Syndrome: Analysis of the Clinical Characteristics and Gene Mutations in 42 Patients.

Published in:

Journal of the Endocrine Society, 2024, v. 8, n. 8, p. 1, doi. 10.1210/jendso/bvae123

By:

Gong, Wenfeng;
Chen, Wenzhe;
Dong, Jianjun;
Liao, Lin

Publication type:

Article

灵芝醇提物对改善 3T3-L1 脂肪细胞胰岛素抵抗的作用.

Published in:

Food Research & Development, 2022, v. 43, n. 12, p. 22, doi. 10.12161/j.issn.1005-6521.2022.12.004

By:

谭孟芳;
康信聪;
周佳丽;
杨兰;
刘东波

Publication type:

Article

The multifaceted role of cytochrome P450-Derived arachidonic acid metabolites in diabetes and diabetic cardiomyopathy.

Published in:

Drug Metabolism Reviews, 2022, v. 54, n. 2, p. 141, doi. 10.1080/03602532.2022.2051045

By:

Isse, Fadumo Ahmed;
El-Sherbeni, Ahmed A.;
El-Kadi, Ayman O. S.

Publication type:

Article

Mechanistic evaluation of Jiu Wei Qing Zhi Gao in non-alcoholic fatty liver disease: insights from network Pharmacology and experimental validation.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00427-2

By:

Chen, Qinlei;
Hu, Qianfeng;
Zhang, Fan;
Lu, Weiting;
Yuan, Zheng;
Qiao, Fei

Publication type:

Article

Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 12, p. 2033, doi. 10.3390/jcm8122033

By:

Bourebaba, Lynda;
Marycz, Krzysztof

Publication type:

Article

Effects of estrogens in mitochondria: An approach to type 2 diabetes.

Published in:

AIMS Molecular Science, 2024, v. 11, n. 1, p. 72, doi. 10.3934/molsci.2024006

By:

Ruiz-Romero, Geovanni Alberto;
Álvarez-Delgado, Carolina

Publication type:

Article

Alzheimer's disease: Is there a relationship between brain reninangiotensin system, estradiol and glucose transporter-4 (GLUT-4)?

Published in:

AIMS Molecular Science, 2023, v. 10, n. 2, p. 37, doi. 10.3934/molsci.2023004

By:

Carrera-González, María Pilar;
Ramírez-Expósito, María Jesús;
Guerrero-González, Carmen;
Martínez-Martos, José Manuel

Publication type:

Article

(1′ S)-1′-Acetoxyeugenol Acetate Enhances Glucose-Stimulated Insulin Secretion.

Published in:

Plants (2223-7747), 2023, v. 12, n. 3, p. 579, doi. 10.3390/plants12030579

By:

Lee, Dahae;
Son, So-Ri;
Qi, Yutong;
Kang, Ki Sung;
Jang, Dae Sik

Publication type:

Article

(-)-Leucophyllone, a Tirucallane Triterpenoid from Cornus walteri , Enhances Insulin Secretion in INS-1 Cells.

Published in:

Plants (2223-7747), 2021, v. 10, n. 3, p. 431, doi. 10.3390/plants10030431

By:

Lee, Dahae;
Kim, Ki Hyun;
Jang, Taesu;
Kang, Ki Sung;
Maggi, Filippo

Publication type:

Article

Psoriatic Arthritis and Diabetes Mellitus: A Narrative Review.

Published in:

Rheumatology & Therapy, 2020, v. 7, n. 2, p. 271, doi. 10.1007/s40744-020-00206-7

By:

Dal Bello, Giacomo;
Gisondi, Paolo;
Idolazzi, Luca;
Girolomoni, Giampiero

Publication type:

Article

Upregulated insulin receptor tyrosine kinase substrate promotes the proliferation of colorectal cancer cells via the bFGF/AKT signaling pathway.

Published in:

Gastroenterology Report, 2021, v. 9, n. 2, p. 166, doi. 10.1093/gastro/goaa032

By:

Wang, Song;
Liu, Zheng;
Ma, Yi-Ming;
Guan, Xu;
Jiang, Zheng;
Sun, Peng;
Liu, En-Rui;
Zhang, Yu-Kun;
Wang, Hong-Ying;
Wang, Xi-Shan

Publication type:

Article

EFFECT OF BIOACTIVE EXTRACTS WITH HIGH CYTOKININS CONTENT FROM MICELIAL BIOMASS OF HERICIUM CORALLOIDES AND FOMITOPSIS OFFICINALIS ON TUMOR CELLS IN VITRO.

Published in:

Bulletin of Taras Shevchenko National University of Kyiv / Vestnik Kievskogo Nacional'Nogo Universiteta Imeni Tarasa Ševčenko, 2019, v. 79, n. 3, p. 31, doi. 10.17721/1728_2748.2019.79.31-37

By:

Vedenicheva, N.;
Kosakivska, I.;
Kholodny, M. G.;
Garmanchuk, L.;
Ostapchenko, L.

Publication type:

Article

Klotho plays a critical role in clear cell renal cell carcinoma progression and clinical outcome.

Published in:

Korean Journal of Physiology & Pharmacology, 2016, v. 20, n. 3, p. 297, doi. 10.4196/kjpp.2016.20.3.297

By:

Ji-Hee Kim;
Kyu-Hee Hwang;
Sayamaa Lkhagvadorj;
Jae Hung Jung;
Hyun Chul Chung;
Kyu-Sang Park;
In Deok Kong;
Minseob Eom;
Seung-Kuy Cha

Publication type:

Article

АСПЕКТИ НА БИОИКОНОФИЗИЧНА ФАРМАКОЛОГИЯ В ЛЕЧЕНИЕТО НА ЗАХАРЕН ДИАБЕТ.

Published in:

Management & Education / Upravlenie i Obrazovanie, 2021, v. 17, n. 6, p. 198

By:

Петров, Михай

Publication type:

Article

Variants of Insulin-Signaling Inhibitor Genes in Type 2 Diabetes and Related Metabolic Abnormalities.

Published in:

International Journal of Genomics, 2013, p. 1, doi. 10.1155/2013/376454

By:

de Lorenzo, Carlo;
Greco, Annalisa;
Fiorentino, Teresa Vanessa;
Mannino, Gaia Chiara;
Hribal, Marta Letizia

Publication type:

Article

Distinct Effects of Carrageenan and High-Fat Consumption on the Mechanisms of Insulin Resistance in Nonobese and Obese Models of Type 2 Diabetes.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/9582714

By:

Bhattacharyya, Sumit;
Feferman, Leo;
Tobacman, Joanne K.

Publication type:

Article

Alterations in insulin receptor signalling in the rat epitrochlearis muscle upon cessation of voluntary exercise.

Published in:

Journal of Physiology, 2005, v. 562, n. 3, p. 829, doi. 10.1113/jphysiol.2004.073593

By:

Kump, David S.;
Booth, Frank W.

Publication type:

Article

Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.

Published in:

Experimental Physiology, 2013, v. 98, n. 2, p. 526, doi. 10.1113/expphysiol.2012.066357

By:

Ching, James Kain;
Luebbert, Stephen H.;
Collins IV, Roy L.;
Zhang, Zhihong;
Marupudi, Nandhini;
Banerjee, Sankha;
Hurd, Robin D.;
Ralston, Lyle;
Fisher, Jonathan S.

Publication type:

Article

MicroRNA-126 inhibits the migration and invasion of endometrial cancer cells by targeting insulin receptor substrate 1.

Published in:

Oncology Letters, 2021, v. 22, n. 3, p. N.PAG, doi. 10.3892/ol.2021.12906

By:

Zhao, Xiumin;
Zhu, Danyang;
Lu, Cailing;
Yan, Dewen;
Li, Lifeng;
Chen, Zhoufang

Publication type:

Article