Works matching AU Pao, William

Results: 62

Induction of BIM Is Essential for Apoptosis Triggered by EGFR Kinase Inhibitors in Mutant EGFR-Dependent Lung Adenocarcinomas.

Published in:

PLoS Medicine, 2007, v. 4, n. 10, p. e294, doi. 10.1371/journal.pmed.0040294

By:

Yixuan Gong;
Somwar, Romel;
Politi, Katerina;
Balak, Marissa;
Chmielecki, Juliann;
Xuejun Jiang;
Pao, William

Publication type:

Article

Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain.

Published in:

PLoS Medicine, 2005, v. 2, n. 3, p. 225, doi. 10.1371/journal.pmed.0020073

By:

Pao, William;
Miller, Vincent A.;
Politi, Katerina A.;
Riely, Gregory J.;
Somwar, Romel;
Zakowski, Maureen F.;
Kris, Mark G.;
Varmus, Harold

Publication type:

Article

KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib.

Published in:

PLoS Medicine, 2005, v. 2, n. 1, p. 57, doi. 10.1371/journal.pmed.0020017

By:

Pao, William;
Wang, Theresa Y.;
Riely, Gregory J.;
Miller, Vincent A.;
Qiulu Pan;
Ladanyi, Marc;
Zakowski, Maureen F.;
Heelan, Robert T.;
Kris, Mark G.;
Varmus, Harold E.

Publication type:

Article

Fully coupled modeling of seabed subsidence and reservoir compaction of North Sea oil fields.

Published in:

Hydrogeology Journal, 2003, v. 11, n. 1, p. 142, doi. 10.1007/s10040-002-0239-z

By:

Lewis, Roland W.;
Makurat, Axel;
Pao, William K. S.

Publication type:

Article

Patterns and processes of somatic mutations in nine major cancers.

Published in:

BMC Medical Genomics, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1755-8794-7-11

By:

Peilin Jia;
William Pao;
Zhongming Zhao

Publication type:

Article

Anchored multiplex PCR for targeted next-generation sequencing.

Published in:

Nature Medicine, 2014, v. 20, n. 12, p. 1479, doi. 10.1038/nm.3729

By:

Zheng, Zongli;
Liebers, Matthew;
Zhelyazkova, Boryana;
Cao, Yi;
Panditi, Divya;
Lynch, Kerry D;
Chen, Juxiang;
Robinson, Hayley E;
Shim, Hyo Sup;
Chmielecki, Juliann;
Pao, William;
Engelman, Jeffrey A;
Iafrate, A John;
Le, Long Phi

Publication type:

Article

Chipping away at the lung cancer genome.

Published in:

Nature Medicine, 2012, v. 18, n. 3, p. 349, doi. 10.1038/nm.2697

By:

Pao, William;
Hutchinson, Katherine E

Publication type:

Article

Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies.

Published in:

Nature Genetics, 2010, v. 42, n. 1, p. 77, doi. 10.1038/ng.491

By:

Veeriah, Selvaraju;
Taylor, Barry S.;
Meng, Shasha;
Fang Fang;
Yilmaz, Emrullah;
Vivanco, Igor;
Janakiraman, Manickam;
Schultz, Nikolaus;
Hanrahan, Aphrothiti J.;
Pao, William;
Ladanyi, Marc;
Sander, Chris;
Heguy, Adriana;
Holland, Eric C.;
Paty, Philip B.;
Mischel, Paul S.;
Liau, Linda;
Cloughesy, Timothy F.;
Mellinghoff, Ingo K.;
Solit, David B.

Publication type:

Article

Morphologic Features of Adenocarcinoma of the Lung Predictive of Response to the Epidermal Growth Factor Receptor Kinase Inhibitors Erlotinib and Gefitinib.

Published in:

Archives of Pathology & Laboratory Medicine, 2009, v. 133, n. 3, p. 470, doi. 10.5858/133.3.470

By:

Zakowski, Maureen F.;
Hussain, Sanaa;
Pao, William;
Ladanyi, Marc;
Ginsberg, Michelle S.;
Heelan, Robert;
Miller, Vincent A.;
Rusch, Valerie W.;
Kris, Mark G.

Publication type:

Article

Modified Yield Power-Law fluid flow in narrow annuli with inner rotating pipe.

Published in:

Canadian Journal of Chemical Engineering, 2015, v. 93, n. 1, p. 150, doi. 10.1002/cjce.22100

By:

Ofei, Titus Ntow;
Irawan, Sonny;
Pao, William;
Osgouei, Reza Ettehadi

Publication type:

Article

A Preliminary Numerical Investigation of Thermal Mixing Efficiency in T-Junctions with Different Flow Configurations.

Published in:

International Journal of Heat & Technology, 2021, v. 39, n. 5, p. 1590, doi. 10.18280/ijht.390522

By:

Nuruzzaman, Md;
Pao, William;
Ejaz, Faheem;
Ya, Hamdan

Publication type:

Article

JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors.

Published in:

Science Signaling, 2016, v. 9, n. 421, p. 1, doi. 10.1126/scisignal.aac8460

By:

Gao, Sizhi P.;
Qing Chang;
Ninghui Mao;
Daly, Laura A.;
Vogel, Robert;
Chan, Tyler;
Shu Hui Liu;
Bournazou, Eirini;
Schori, Erez;
Haiying Zhang;
Brewer, Monica Red;
Pao, William;
Morris, Luc;
Ladanyi, Marc;
Arcila, Maria;
Manova-Todorova, Katia;
de Stanchina, Elisa;
Norton, Larry;
Levine, Ross L.;
Altan-Bonnet, Gregoire

Publication type:

Article

Consensus Rules in Variant Detection from Next-Generation Sequencing Data.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038470

By:

Peilin Jia;
Fei Li;
Jufeng Xia;
Haiquan Chen;
Hongbin Ji;
William Pao;
Zhongming Zhao

Publication type:

Article

Routine Multiplex Mutational Profiling of Melanomas Enables Enrollment in Genotype-Driven Therapeutic Trials.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035309

By:

Lovly, Christine M.;
Dahlman, Kimberly Brown;
Fohn, Laurel E.;
Su, Zengliu;
Dias-Santagata, Dora;
Hicks, Donna J.;
Hucks, Donald;
Berry, Elizabeth;
Terry, Charles;
Duke, MarKeesa;
Su, Yingjun;
Sobolik-Delmaire, Tammy;
Richmond, Ann;
Kelley, Mark C.;
Vnencak-Jones, Cindy L.;
Iafrate, A. John;
Sosman, Jeffrey;
Pao, William

Publication type:

Article

Spectrum of Oncogenic Driver Mutations in Lung Adenocarcinomas from East Asian Never Smokers.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028204

By:

Chenguang Li;
Rong Fang;
Yihua Sun;
Xiangkun Han;
Fei Li;
Bin Gao;
Iafrate, A. John;
Xin- Yuan Liu;
William Pao;
Haiquan Chen;
Hongbin Ji

Publication type:

Article

High Expression Levels of Total IGF-1R and Sensitivity of NSCLC Cells In Vitro to an Anti-IGF-1R Antibody (R1507).

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007273

By:

Yixuan Gong;
Evelyn Yao;
Shen, Ronglai;
Goel, Aviva;
Arcila, Maria;
Teruya-Feldstein, Julie;
Zakowski, Maureen F.;
Frankel, Stanley;
Peifer, Martin;
Thomas, Roman K.;
Ladanyi, Marc;
Pao, William

Publication type:

Article

Twice weekly pulse and daily continuous-dose erlotinib as initial treatment for patients with epidermal growth factor receptor-mutant lung cancers and brain metastases.

Published in:

2018

By:

Arbour, Kathryn C.;
Kris, Mark G.;
Riely, Gregory J.;
Ni, Ai;
Beal, Kathryn;
Daras, Mariza;
Hayes, Sara A.;
Young, Robert J.;
Rodriguez, Christopher R.;
Ahn, Linda;
Pao, William;
Yu, Helena A.

Publication type:

journal article

Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas.

Published in:

Cancer (0008543X), 2013, v. 119, n. 2, p. 356, doi. 10.1002/cncr.27730

By:

Johnson, Melissa L.;
Sima, Camelia S.;
Chaft, Jamie;
Paik, Paul K.;
Pao, William;
Kris, Mark G.;
Ladanyi, Marc;
Riely, Gregory J.

Publication type:

Article

CUSTOM-SEQ: a prototype for oncology rapid learning in a comprehensive EHR environment.

Published in:

2016

By:

Warner, Jeremy L.;
Wang, Lucy;
Pao, William;
Sosman, Jeffrey A.;
Atreya, Ravi V.;
Carney, Pam;
Levy, Mia A.

Publication type:

journal article

Influence of Sand Fines Transport Velocity on Erosion-Corrosion Phenomena of Carbon Steel 90-Degree Elbow.

Published in:

Metals (2075-4701), 2020, v. 10, n. 5, p. 626, doi. 10.3390/met10050626

By:

Khan, Rehan;
H. Ya, Hamdan;
Pao, William;
bin Abdullah, Mohamad Zaki;
Dzubir, Faizul Azly

Publication type:

Article

An Experimental Study on the Erosion-Corrosion Performance of AISI 1018 Carbon Steel and AISI 304L Stainless Steel 90-Degree Elbow Pipe.

Published in:

Metals (2075-4701), 2019, v. 9, n. 12, p. 1260, doi. 10.3390/met9121260

By:

Khan, Rehan;
H. Ya, Hamdan;
Pao, William

Publication type:

Article

Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs.

Published in:

JAMA: Journal of the American Medical Association, 2014, v. 311, n. 19, p. 1998, doi. 10.1001/jama.2014.3741

By:

Kris, Mark G.;
Johnson, Bruce E.;
Berry, Lynne D.;
Kwiatkowski, David J.;
Iafrate, A. John;
Wistuba, Ignacio I.;
Varella-Garcia, Marileila;
Franklin, Wilbur A.;
Aronson, Samuel L.;
Pei-Fang Su;
Yu Shyr;
Camidge, D. Ross;
Sequist, Lecia V.;
Glisson, Bonnie S.;
Khuri, Fadlo R.;
Garon, Edward B.;
Pao, William;
Rudin, Charles;
Schiller, Joan;
Haura, Eric B.

Publication type:

Article

Phase 1 Trial of Everolimus and Gefitinib in Patients With Advanced Nonsmall-Cell Lung Cancer.

Published in:

Cancer (0008543X), 2007, v. 110, n. 3, p. 599, doi. 10.1002/cncr.22816

By:

Milton, Daniel T.;
Riely, Gregory J.;
Azzoli, Christopher G.;
Gomez, Jorge E.;
Heelan, Robert T.;
Kris, Mark G.;
Krug, Lee M.;
Pao, William;
Pizzo, Barbara;
Rizvi, Naiyer A.;
Miller, Vincent A.

Publication type:

Article

A phase I/II study of weekly high‐dose erlotinib in previously treated patients with nonsmall cell lung cancerPresented in part at the 2004 American Society of Clinical Oncology Meeting, New Orleans, Louisiana, June 5–8, 2004.

Published in:

Cancer (0008543X), 2006, v. 107, n. 5, p. 1034

By:

Daniel T. Milton;
Christopher G. Azzoli;
Robert T. Heelan;
Ennapadam Venkatraman;
Jorge E. Gomez;
Mark G. Kris;
Lee M. Krug;
William Pao;
Naiyer A. Rizvi;
Megan Dunne;
Vincent A. Miller

Publication type:

Article

Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.

Published in:

2009

By:

Regales, Lucia;
Gong, Vixuan;
Shen, Ronglai;
de Stanchina, Elisa;
Vivanco, Igor;
Goel, Aviva;
Koutcher, Jason A.;
Spassova, Maria;
Ouerfelli, Ouathek;
Mellinghoff, Ingo K.;
Zakowski, Maureen F.;
Politi, Katerina A.;
Pao, William;
Gong, Yixuan

Publication type:

journal article

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Published in:

2007

By:

Gao, Sizhi Paul;
Mark, Kevin G;
Leslie, Kenneth;
Pao, William;
Motoi, Noriko;
Gerald, William L;
Travis, William D;
Bornmann, William;
Veach, Darren;
Clarkson, Bayard;
Bromberg, Jacqueline F

Publication type:

journal article

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3846, doi. 10.1172/JCI31871

By:

Sizhi Paul Gao;
Mark, Kevin G.;
Leslie, Kenneth;
Pao, William;
Motoi, Noriko;
Gerald, William L.;
Travis, William D.;
Bornmann, William;
Veach, Darren;
Clarkson, Bayard;
Bromberg, Jacqueline F.

Publication type:

Article

Predicting Sensitivity of Non—Small-Cell Lung Cancer to Gefitinib: Is There a Role for P-Akt?

Published in:

JNCI: Journal of the National Cancer Institute, 2004, v. 96, n. 15, p. 1117, doi. 10.1093/jnci/djh244

By:

Pao, William;
Miller, Vincent A.;
Venkatraman, Ennapadam;
Kris, Mark G.

Publication type:

Article

Characterizing Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in an EGFR Mutant Lung Adenocarcinoma Cell Line.

Published in:

Vanderbilt Undergraduate Research Journal, 2013, v. 9, p. 1

By:

Jing Sun;
Kadoaki Ohashi;
Pao, William

Publication type:

Article

High dose weekly erlotinib achieves therapeutic concentrations in CSF and is effective in leptomeningeal metastases from epidermal growth factor receptor mutant lung cancer.

Published in:

2010

By:

Clarke, Jennifer L.;
William Pao;
Nian Wu;
Miller, Vincent A.;
Lassman, Andrew B.

Publication type:

Report

Application of next generation sequencing to human gene fusion detection: computational tools, features and perspectives.

Published in:

Briefings in Bioinformatics, 2013, v. 14, n. 4, p. 506, doi. 10.1093/bib/bbs044

By:

Wang, Qingguo;
Xia, Junfeng;
Jia, Peilin;
Pao, William;
Zhao, Zhongming

Publication type:

Article

Design of Helical Capacitance Sensor for Holdup Measurement in Two-Phase Stratified Flow: A Sinusoidal Function Approach.

Published in:

Sensors (14248220), 2016, v. 16, n. 7, p. 1032, doi. 10.3390/s16071032

By:

Lim, Lam Ghai;
Pao, William K. S.;
Hamid, Nor Hisham;
Tang, Tong Boon

Publication type:

Article

Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.

Published in:

Genes, Chromosomes & Cancer, 2012, v. 51, n. 1, p. 54, doi. 10.1002/gcc.20930

By:

Chmielecki, Juliann;
Peifer, Martin;
Viale, Agnes;
Hutchinson, Katherine;
Giltnane, Jennifer;
Socci, Nicholas D.;
Hollis, Clayton J.;
Dean, Rebecca S.;
Yenamandra, Ashwini;
Jagasia, Madan;
Kim, Annette S.;
Davé, Utpal P.;
Thomas, Roman K.;
Pao, William

Publication type:

Article

MET Exon 14 Skipping in Non-Small Cell Lung Cancer.

Published in:

Oncologist, 2016, v. 21, n. 4, p. 481, doi. 10.1634/theoncologist.2015-0510

By:

Heist, Rebecca S.;
Shim, Hyo Sup;
Gingipally, Shalini;
Mino‐Kenudson, Mari;
Le, Long;
Gainor, Justin F.;
Zheng, Zongli;
Aryee, Martin;
Xia, Junfeng;
Jia, Peilin;
Jin, Hailing;
Zhao, Zhongming;
Pao, William;
Engelman, Jeffrey A.;
Iafrate, A. John

Publication type:

Article

Enabling a Genetically Informed Approach to Cancer Medicine: A Retrospective Evaluation of the Impact of Comprehensive Tumor Profiling Using a Targeted Next-Generation Sequencing Panel.

Published in:

Oncologist, 2014, v. 19, n. 6, p. 616, doi. 10.1634/theoncologist.2014-0011

By:

Johnson, Douglas B.;
Dahlman, Kimberly H.;
Knol, Jared;
Gilbert, Jill;
Puzanov, Igor;
Means‐Powell, Julie;
Balko, Justin M.;
Lovly, Christine M.;
Murphy, Barbara A.;
Goff, Laura W.;
Abramson, Vandana G.;
Crispens, Marta A.;
Mayer, Ingrid A.;
Berlin, Jordan D.;
Horn, Leora;
Keedy, Vicki L.;
Reddy, Nishitha M.;
Arteaga, Carlos L.;
Sosman, Jeffrey A.;
Pao, William

Publication type:

Article

Effect of Sand Fines Concentration on the Erosion-Corrosion Mechanism of Carbon Steel 90° Elbow Pipe in Slug Flow.

Published in:

Materials (1996-1944), 2020, v. 13, n. 20, p. 4601, doi. 10.3390/ma13204601

By:

Khan, Rehan;
H. Ya, Hamdan;
Pao, William;
Majid, Mohd Amin Abd;
Ahmed, Tauseef;
Ahmad, Amir;
Alam, Mohammad Azad;
Azeem, M.;
Iftikhar, Hassan

Publication type:

Article

Erosion–Corrosion of 30°, 60°, and 90° Carbon Steel Elbows in a Multiphase Flow Containing Sand Particles.

Published in:

Materials (1996-1944), 2019, v. 12, n. 23, p. 3898, doi. 10.3390/ma12233898

By:

Khan, Rehan;
Ya, Hamdan H.;
Pao, William;
Khan, Armaghan

Publication type:

Article

Primary extracranial neuroblastoma with central nervous system metastases characterization by clinicopathologic findings and neuroimaging.

Published in:

1991

By:

Kellie, Stewart J.;
Ann Hayes, F.;
Bowman, Laura;
Kovnar, Edward H.;
Langston, James;
Jenkins, Jesse J.;
Pao, William J.;
Ducos, Raphael;
Green, Alexander A.;
Kellie, S J;
Hayes, F A;
Bowman, L;
Kovnar, E H;
Langston, J;
Jenkins, J J 3rd;
Pao, W J;
Ducos, R;
Green, A A

Publication type:

journal article

Comparable rate of EGFR kinase domain mutation in lung adenocarcinomas from Chinese male and female never-smokers.

Published in:

2010

By:

Yi-hua SUN;
Rong FANG;
Bin GAO;
Xiang-kun HAN;
Jun-hua ZHANG;
PAO, William;
Hai-quan CHEN;
Hong-bin JI

Publication type:

Letter

Characterization of breast cancers with PI3K mutations in an academic practice setting using SNaPshot profiling.

Published in:

Breast Cancer Research & Treatment, 2014, v. 145, n. 2, p. 389, doi. 10.1007/s10549-014-2945-3

By:

Abramson, Vandana;
Cooper Lloyd, M.;
Ballinger, Tarah;
Sanders, Melinda;
Du, Liping;
Lai, Darson;
Su, Zengliu;
Mayer, Ingrid;
Levy, Mia;
LaFrance, Delecia;
Vnencak-Jones, Cindy;
Shyr, Yu;
Dahlman, Kimberly;
Pao, William;
Arteaga, Carlos

Publication type:

Article

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer.

Published in:

2010

By:

Pao, William;
Chmielecki, Juliann

Publication type:

journal article

DESIGN AND DEVELOPMENT OF FANGER MODEL AND FUZZY LOGIC BASED CONTROLLER FOR AIR CONDITIONERS.

Published in:

e-BANGI Journal, 2019, v. 16, n. 3, p. 1

By:

Keh-Kim Kee;
Robin, Angelo Emanuel;
Pao, William K. S.

Publication type:

Article

Germinal center formation in mice lacking αβ T cells.

Published in:

European Journal of Immunology, 1996, v. 26, n. 7, p. 1603, doi. 10.1002/eji.1830260729

By:

Dianda, Lee;
Gulbranson-Judge, Adam;
Pao, William;
Hayday, Adrian C.;
Maclennan, Ian C. M.;
Owen, Michael J.

Publication type:

Article

A MULTIPHASE FLOW LOOP DESIGN FOR INVESTIGATING THE PARTIAL PHASE SEPARATION IN A PIPE TEE.

Published in:

Acta Polytecnica: Journal of Advanced Engineering, 2019, v. 59, n. 4, p. 399, doi. 10.14311/AP.2019.59.0399

By:

SAIEED, AHMED;
MEMON, ZEESHAN QADIR;
TRAN, MINH CONG;
SOON, WILLIAM PAO KING

Publication type:

Article

Dose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer Patients.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141665

By:

Liu, Lin L.;
Li, Fei;
Pao, William;
Michor, Franziska

Publication type:

Article

Effects of Selection of Inlet Perturbations, Multiphase and Turbulence Equations on Slug Flow Characteristics Using Altair ® AcuSolve™.

Published in:

Processes, 2021, v. 9, n. 12, p. 2152, doi. 10.3390/pr9122152

By:

Abdul Basith, Mohammad Sobir;
Sallih, Nabihah;
Soon, William Pao King;
Shibano, Shinji Thomas;
Singh, Ramesh;
Sulong, Mohd Ayub

Publication type:

Article

MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis.

Published in:

Genome Biology, 2014, v. 15, n. 10, p. 1, doi. 10.1186/s13059-014-0489-9

By:

Peilin Jia;
Quan Wang;
Qingxia Chen;
Hutchinson, Katherine E.;
William Pao;
Zhongming Zhao

Publication type:

Article

Investigation of the liquid carryovers in the branching T-junction, based on historical data.

Published in:

Petroleum Science & Technology, 2024, v. 42, n. 17, p. 2133, doi. 10.1080/10916466.2022.2158198

By:

Ejaz, Faheem;
Pao, William;
Ali, Hafiz Muhammad;
Saieed, Ahmed

Publication type:

Article

Escaping ALK Inhibition: Mechanisms of and Strategies to Overcome Resistance.

Published in:

Science Translational Medicine, 2012, v. 4, n. 120, p. 1, doi. 10.1126/scitranslmed.3003728

By:

Lovly, Christine M.;
Pao, William

Publication type:

Article

Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies.

Published in:

Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0408-2

By:

Hartmaier, Ryan J.;
Charo, Jehad;
Fabrizio, David;
Goldberg, Michael E.;
Albacker, Lee A.;
Pao, William;
Chmielecki, Juliann

Publication type:

Article