Works matching DE "SAQUINAVIR"

Results: 45

Use of Nonrecommended Antivirals Among Medicare Beneficiaries With HIV.

Published in:

JAMA Network Open, 2025, v. 8, n. 4, p. e258296, doi. 10.1001/jamanetworkopen.2025.8296

By:

Figueroa, Jose F.;
Dai, Dannie;
Ebem, Florence;
Duggan, Ciara;
Chu, Jacqueline;
Luu, Grace;
Phelan, Jessica;
Gandhi, Rajesh T.;
Orav, E. John;
Hyle, Emily P.

Publication type:

Article

Comparative Single Dose Pharmacokinetics and Bioavailability Studies of Saquinavir, Ritonavir and their Optimized Cyclodextrin Complexes after Oral Administration into Rats using LC-MS/MS.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2018, v. 52, n. 4, p. 587, doi. 10.5530/ijper.52.4.68

By:

Sogai, Bharani S.;
Narayansetty, Vikram B.;
Kolapalli, Ramana Murthy V.

Publication type:

Article

HIV protease inhibitors in pulmonary hypertension: rationale and design of a pilot trial in idiopathic pulmonary arterial hypertension.

Published in:

Pulmonary Circulation, 2015, v. 5, n. 3, p. 538, doi. 10.1086/682426

By:

Ying Li;
Xiao-hui Li;
Zai-xin Yu;
Jing-jing Cai;
Billiar, Timothy R.;
Chen, Alex F.;
Ben Lv;
Zi-ying Chen;
Zhi-jun Huang;
Guo-ping Yang;
Jie Song;
Bin Liu;
Hong Yuan

Publication type:

Article

No-Modified Saquinavir is Equally Efficient Against Doxorubicin Sensitive and Resistant Non-Small Cell Lung Carcinoma Cells / MODIFIKOVANA KOVANA FORMA SAKVINAVIRA EFIKASNO SU PRIMI RA RAST ĆELIJA NESITNOĆELIJSKOG KARCINOMA PLUĆA RAZLIČITE OSETUIVOSTI NA DOKSORUBICIN

Published in:

Journal of Medical Biochemistry, 2013, v. 32, n. 4, p. 406, doi. 10.2478/jomb-2013-0050

By:

Mijatović, Sanja;
Pešić, Milica;
Mojić, Marija;
Banković, Jasna;
Miljković, Đorde;
Fagone, Paolo;
Mangano, Katia;
Nicoletti, Ferdinando;
McCubrey, James;
Tanić, Nikola;
Maksimović-Ivanić, Danijela

Publication type:

Article

The efficacy and tolerability of combination antiretroviral therapy in pregnancy: infant and maternal outcome.

Published in:

2000

By:

Clarke, S M;
Mulcahy, F;
Healy, C M;
Condon, S;
Butler, K M

Publication type:

journal article

Gynaecomastia associated with combination antiretroviral therapy including protease inhibitors for human immunodeficiency virus infection.

Published in:

1999

By:

Post, Jeffrey J.;
Post, J J

Publication type:

journal article

Gynaecomastia associated with saquinavir therapy.

Published in:

1999

By:

Donovan, Basil;
Bodsworth, Neil J.;
Mulhall, Brian P.;
Allen, Debbie;
Donovan, B;
Bodsworth, N J;
Mulhall, B P;
Allen, D

Publication type:

journal article

New-Onset Saquinavir-Induced Diabetes.

Published in:

Diabetes Care, 2013, v. 36, n. 12, p. e199, doi. 10.2337/dc13-1645

By:

VAN ZOELEN, MARIEKE A. D.;
HOEPELMAN, A. I. M.;
DE VALK, H. W.

Publication type:

Article

Drug binding dynamics of the dimeric SARS-CoV-2 main protease, determined by molecular dynamics simulation.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74099-5

By:

Komatsu, Teruhisa S.;
Okimoto, Noriaki;
Koyama, Yohei M.;
Hirano, Yoshinori;
Morimoto, Gentaro;
Ohno, Yousuke;
Taiji, Makoto

Publication type:

Article

INFLUENCE OF POMEGRANATE JUICE ON THE CYP3A4-MEDIATED METABOLISM AND P-GLYCOPROTEIN MEDIATED TRANSPORT OF SAQUINAVIR IN VIVO AND EX VIVO MODELS.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2016, v. 27, n. 3, p. 152, doi. 10.14499/indonesianjpharm27iss3pp152

By:

Vemulapalli, Sridhar;
Mullapudi, Surya Sandeep;
Pingili, Ravindrababu;
Kothapalli, Ramya;
Kondru, Sivaramakrishna;
Kilaru, Naveenbabu

Publication type:

Article

The antiretroviral agent saquinavir enhances hTERT expression and telomerase activity in human T leukaemia cells in vitro.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2013, v. 32, n. 1, p. 1, doi. 10.1186/1756-9966-32-38

By:

Adamo, Riccardo;
Comandini, Alessandro;
Aquino, Angelo;
Bonmassar, Laura;
Guglielmi, Loredana;
Bonmassar, Enzo;
Franzese, Ornella

Publication type:

Article

Garlic: A brief overview of its interaction with chemical drugs.

Published in:

Plant Biotechnology Persa, 2020, p. 31, doi. 10.52547/pbp.2.2.31

By:

Eftekhari, Zohre

Publication type:

Article

Nonprogressive CMV retinitis in AIDS patients with protease inhibitors therapy for AIDS.

Published in:

1997

By:

Ortega-Larrocea, Gabriela;
Feregrino-Goyos, Manuel;
Ortega-Larrocea, G;
Feregrino-Goyos, M

Publication type:

journal article

Crystal structure of the retroviral protease‐like domain of a protozoal DNA damage‐inducible 1 protein.

Published in:

FEBS Open Bio, 2018, v. 8, n. 9, p. 1379, doi. 10.1002/2211-5463.12491

By:

Kumar, Sushant;
Suguna, Kaza

Publication type:

Article

Mechanisms of Pharmacokinetic Enhancement Between Ritonavir and Saquinavir; Micro/Small Dosing Tests Using Midazolam (CYP3A4), Fexofenadine (p-Glycoprotein), and Pravastatin (OATP1B1) as Probe Drugs Mechanisms of Pharmacokinetic Enhancement Between Ritonavir and Saquinavir; Micro/Small Dosing Tests Using Midazolam (CYP3A4), Fexofenadine (p-Glycoprotein), and Pravastatin (OATP1B1) as Probe Drugs

Published in:

Journal of Clinical Pharmacology, 2013, v. 53, n. 6, p. 654, doi. 10.1002/jcph.62

By:

Ieiri, Ichiro;
Tsunemitsu, Shyohei;
Maeda, Kazuya;
Ando, Yukie;
Izumi, Noritomo;
Kimura, Miyuki;
Yamane, Naoe;
Okuzono, Tsuyoshi;
Morishita, Mariko;
Kotani, Naoki;
Kanda, Eri;
Deguchi, Mariko;
Matsuguma, Kyoko;
Matsuki, Shunji;
Hirota, Takeshi;
Irie, Shin;
Kusuhara, Hiroyuki;
Sugiyama, Yuichi

Publication type:

Article

Identification of degradation products of saquinavir mesylate by ultra-high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry and its application to quality control.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2017, v. 31, n. 9, p. 771, doi. 10.1002/rcm.7842

By:

Thummar, Mohit;
Patel, Prinesh N.;
Petkar, Arun L.;
Swain, Debasish;
Srinivas, R.;
Samanthula, Gananadhamu

Publication type:

Article

Structural Basis of Why Nelfinavir-Resistant D30N Mutant of HIV-1 Protease Remains Susceptible to Saquinavir.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 3, p. 302, doi. 10.1111/cbdd.12494

By:

Prashar, Vishal;
Bihani, Subhash C.;
Ferrer, Jean ‐ Luc;
Hosur, Madhusoodan V.

Publication type:

Article

Enhancement of cellular uptake, transport and oral absorption of protease inhibitor saquinavir by nanocrystal formulation.

Published in:

Acta Pharmacologica Sinica, 2015, v. 36, n. 9, p. 1151, doi. 10.1038/aps.2015.53

By:

He, Yuan;
Xia, Deng-ning;
Li, Qiu-xia;
Tao, Jin-song;
Gan, Yong;
Wang, Chi

Publication type:

Article

Saquinavir Induced Suicidal Death of Human Erythrocytes.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2015, v. 37, n. 5, p. 1973, doi. 10.1159/000438558

By:

Waibel, Sabrina;
Bissinger, Rosi;
Bouguerra, Ghada;
abbès, Salem;
Lang, Florian

Publication type:

Article

Inhibition of MMP-9 expression by ritonavir or saquinavir is associated with inactivation of the AKT/Fra-1 pathway in cervical intraepithelial neoplasia cells.

Published in:

Oncology Letters, 2017, v. 13, n. 5, p. 2903, doi. 10.3892/ol.2017.5835

By:

BACIGALUPO, ILARIA;
PALLADINO, CLELIA;
LEONE, PATRIZIA;
TOSCHI, ELENA;
SGADARI, CECILIA;
ENSOLI, BARBARA;
BARILLARI, GIOVANNI

Publication type:

Article

The HIV-protease inhibitor saquinavir reduces proliferation, invasion and clonogenicity in cervical cancer cell lines.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2493, doi. 10.3892/ol.2016.5008

By:

BANDIERA, ELISABETTA;
TODESCHINI, PAOLA;
ROMANI, CHIARA;
ZANOTTI, LAURA;
ERBA, EUGENIO;
COLMEGNA, BENEDETTA;
BIGNOTTI, ELIANA;
SANTIN, ALESSANDRO DAVIDE;
SARTORI, ENRICO;
ODICINO, FRANCO EDOARDO;
PECORELLI, SERGIO;
TASSI, RENATA ALESSANDRA;
RAVAGGI, ANTONELLA

Publication type:

Article

Effect of ritonavir on saquinavir metabolism.

Published in:

2000

By:

Buss, N

Publication type:

commentary

Deciphering the targets of retroviral protease inhibitors in Plasmodium berghei.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201556

By:

Onchieku, Noah Machuki;
Mogire, Reagan;
Ndung'u, Loise;
Mwitari, Peter;
Kimani, Francis;
Matoke-Muhia, Damaris;
Kiboi, Daniel;
Magoma, Gabriel

Publication type:

Article

Saquinavir mesylate: prolongation of QT and PR intervals.

Published in:: WHO Drug Information, 2010, v. 24, n. 2, p. 106
Publication type:: Article

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC.

Published in:

2009

By:

Liptrott, N. J.;
Penny, M.;
Bray, P. G.;
Sathish, J.;
Khoo, S. H.;
Back, D. J.;
Owen, A.

Publication type:

journal article

Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways.

Published in:

Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/7083528

By:

Yu, Zhuang;
Tong, Yao;
Zhang, Renlingzi;
Ding, Xibing;
Li, Quan

Publication type:

Article

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment.

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-58

By:

Dallas, Shannon;
Block, Michelle L.;
Thompson, Deborah M.;
Bonini, Marcelo G.;
Ronaldson, Patrick T.;
Bendayan, Reina;
Miller, David S.

Publication type:

Article

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment.

Published in:

2013

By:

Dallas, Shannon;
Block, Michelle L;
Thompson, Deborah M;
Bonini, Marcelo G;
Ronaldson, Patrick T;
Bendayan, Reina;
Miller, David S

Publication type:

journal article

DEVELOPMENT, CHARACTERIZATION AND BRAIN DISTRIBUTION STUDIES OF NANOSTRUCTURED LIPID CARRIER CONTAINING SAQUINAVIR MESYLATE FOR NASAL ADMINISTRATION.

Published in:

Indian Drugs, 2017, v. 54, n. 9, p. 38, doi. 10.53879/id.54.09.10309

By:

H. S., Mahajan;
M. I., Patel

Publication type:

Article

Nanoemulsion-based intranasal drug delivery system of saquinavir mesylate for brain targeting.

Published in:

Drug Delivery, 2014, v. 21, n. 2, p. 148, doi. 10.3109/10717544.2013.838014

By:

Mahajan, Hitendra S.;
Mahajan, Milind S.;
Nerkar, Pankaj P.;
Agrawal, Anshuman

Publication type:

Article

Saquinavir Loaded Acetalated Dextran Microconfetti - a Long Acting Protease Inhibitor Injectable.

Published in:

Pharmaceutical Research, 2016, v. 33, n. 8, p. 1998, doi. 10.1007/s11095-016-1936-y

By:

Collier, Michael;
Gallovic, Matthew;
Bachelder, Eric;
Sykes, Craig;
Kashuba, Angela;
Ainslie, Kristy

Publication type:

Article

Saquinavir- NO Inhibits IL-6 Production in Macrophages.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 115, n. 6, p. 499, doi. 10.1111/bcpt.12268

By:

Momčilović, Miljana;
Mangano, Katia;
Jevtić, Bojan;
Mammana, Santa;
Stošić‐Grujičić, Stanislava;
Nicoletti, Ferdinando;
Miljković, Djordje

Publication type:

Article

Enhancement of saquinavir absorption and accumulation through the formation of solid drug nanoparticles.

Published in:

BMC Pharmacology & Toxicology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s40360-018-0275-5

By:

Kigen, Gabriel;
Edwards, Geoffrey

Publication type:

Article

A Case of Nephrotic Syndrome, Showing Evidence of Response to Saquinavir.

Published in:

Case Reports in Nephrology, 2015, v. 2015, p. 1, doi. 10.1155/2015/512549

By:

Walters, Giles;
Choudhury, Faisal A.;
Nanayakkara, Budhima

Publication type:

Article

Saquinavir. Clinical pharmacology and efficacy.

Published in:

1998

By:

Vella, S.;
Floridia, M.

Publication type:

journal article

Specific Increase in MDR1 Mediated Drug-Efflux in Human Brain Endothelial Cells following Co-Exposure to HIV-1 and Saquinavir.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0075374

By:

Roy, Upal;
Bulot, Christine;
Honer zu Bentrup, Kerstin;
Mondal, Debasis

Publication type:

Article

Protease inhibitors modulate apoptosis in mesangial cells derived from a mouse model of HIVAN.

Published in:

2004

By:

Mongia, Anil;
Bhaskaran, Madhu;
Reddy, Krishna;
Manjappa, Nagarathna;
Baqi, Noosha;
Singhal, Pravin C

Publication type:

journal article

Comparison of two drug safety signals in a pharmacovigilance data mining framework.

Published in:

2016

By:

Tubert-Bitter, Pascale;
Bégaud, Bernard;
Ahmed, Ismaïl

Publication type:

journal article

Formulation of saquinavir mesylate loaded microparticle by counterion induced aggregation method: Approach by hyperosmotic technique.

Published in:

Drug Invention Today, 2013, v. 5, n. 3, p. 259, doi. 10.1016/j.dit.2013.07.002

By:

Roy, Harekrishna;
Brahma, Chandan Kumar;
Kumar, Ravi;
Nandi, Sisir

Publication type:

Article

Cationic solid lipid nanoparticles with cholesterol-mediated surface layer for transporting saquinavir to the brain.

Published in:

Biotechnology Progress, 2014, v. 30, n. 1, p. 198, doi. 10.1002/btpr.1834

By:

Kuo, Yung‐Chih;
Wang, Cheng‐Chin

Publication type:

Article

Simultaneous determination of lopinavir, saquinavir and ritonavirin in human plasma using liquid chromatography - ion trap mass spectrometry.

Published in:

European Journal of Translational & Clinical Medicine, 2021, v. 4, n. 2, p. 60, doi. 10.31373/ejtcm/139693

By:

Lipiński, Marcin;
Bielawski, Krzysztof P.;
Słomińska, Ewa M.;
Smoleński, Ryszard T.

Publication type:

Article

Effect of a Modified Saquinavir/Ritonavir Dosing Regimen with Lower Dose Lead-In Phase on QTc Interval, Pharmacokinetics, Antiviral Activity and Safety in Treatment-Naïve HIV-1-Infected Patients.

Published in:

Drugs in R&D, 2015, v. 15, n. 1, p. 141, doi. 10.1007/s40268-015-0087-7

By:

Kulkarni, Rohit;
Morcos, Peter;
Boffito, Marta;
Jackson, Akil;
Pozniak, Anton;
Giraudon, Mylene;
Abelardo, Maria;
Patel, Indravadan

Publication type:

Article

Computational drug repurposing study of antiviral drugs against main protease, RNA polymerase, and spike proteins of SARS-CoV-2 using molecular docking method.

Published in:

Journal of Basic & Clinical Physiology & Pharmacology, 2022, v. 33, n. 1, p. 85, doi. 10.1515/jbcpp-2020-0369

By:

Jalalvand, Alireza;
Khatouni, Somayeh Behjat;
Najafi, Zahra Bahri;
Fatahinia, Foroozan;
Ismailzadeh, Narges;
Farahmand, Behrokh

Publication type:

Article

MIMS - UPDATES.

Published in:: Australian Journal of Pharmacy, 2017, v. 98, p. 20
Publication type:: Article

Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy.

Published in:

2002

By:

Gan, Seng Khee;
Samaras, Katherine;
Thompson, Campbell H.;
Kraegen, Edward W.;
Carr, Andrew;
Cooper, David A.;
Chisholm, Donald J.

Publication type:

journal article