Title

Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion.

Authors

Yahalom-Ronen, Yfat; Rajchman, Dana; Sarig, Rachel; Geiger, Benjamin; Tzahor, Eldad

Abstract

The article discusses a study which explores the role of mechanical properties of a network of proteins called matrix in the regulation of cardiomyocyte (CM) maturation in newborn rodents.

Subjects

PROTEINS; HEART cells; RODENT physiology

Publication

eLife, 2015, p1

ISSN

2050-084X

Publication type

Academic Journal

DOI

10.7554/eLife.07455