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- Title
Primidone in the treatment of the long QT syndrome: QT shortening and ventricular arrhythmia suppression.
- Authors
DeSilvey, D L; Moss, A J
- Abstract
We studied a family with the long QT syndrome. The initial case was in a patient who presented with seizures, ventricular fibrillation, and syncope. After a trial of conventional modalities of treatment including left stellate ganglionectomy, primidone (Mysoline) therapy was initiated. This drug has been successful in suppressing ventricular arrhythmias and shortening the QT interval over a 2-year follow-up period. Two additional family members with QT prolongation have been treated with primidone. During an 8-month follow-up, electrocardiographic and Holter recordings showed shortening of the QT interval.
- Publication
Annals of internal medicine, 1980, Vol 93, Issue 1, p53
- ISSN
0003-4819
- Publication type
Journal Article
- DOI
10.7326/0003-4819-93-1-53